{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T03:54:57Z","timestamp":1792036497708,"version":"4.4.0"},"reference-count":42,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,2,1]],"date-time":"2026-02-01T00:00:00Z","timestamp":1769904000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,2,1]],"date-time":"2026-02-01T00:00:00Z","timestamp":1769904000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,12,25]],"date-time":"2025-12-25T00:00:00Z","timestamp":1766620800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/100008102","name":"University of Cincinnati","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100008102","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100017094","name":"Department of Internal Medicine, University of Utah","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100017094","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["World Neurosurgery"],"published-print":{"date-parts":[[2026,2]]},"DOI":"10.1016\/j.wneu.2025.124775","type":"journal-article","created":{"date-parts":[[2026,1,2]],"date-time":"2026-01-02T23:51:43Z","timestamp":1767397903000},"page":"124775","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":1,"special_numbering":"C","title":["Intracranial Candida Auris Infection: A Case Report and Scoping Review"],"prefix":"10.1016","volume":"206","author":[{"ORCID":"https:\/\/orcid.org\/0009-0005-4633-8423","authenticated-orcid":false,"given":"Gabriel L.","family":"Jelkin","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Allie L.","family":"Heineman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0009-9830-4187","authenticated-orcid":false,"given":"Henry T.","family":"Beckett","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christopher M.","family":"Goddard","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7103-971X","authenticated-orcid":false,"given":"Laura B.","family":"Ngwenya","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.wneu.2025.124775_bib1","series-title":"StatPearls Publishing Copyright \u00a9 2025","article-title":"Candida auris. StatPearls","author":"Sikora","year":"2025"},{"key":"10.1016\/j.wneu.2025.124775_bib2","doi-asserted-by":"crossref","DOI":"10.1093\/mmy\/myae042","article-title":"Candida auris-a systematic review to inform the world health organization fungal priority pathogens list","volume":"62","author":"Kim","year":"2024","journal-title":"Med Mycol"},{"key":"10.1016\/j.wneu.2025.124775_bib3","doi-asserted-by":"crossref","DOI":"10.1371\/journal.ppat.1008921","article-title":"Candida auris: epidemiology, biology, antifungal resistance, and virulence","volume":"16","author":"Du","year":"2020","journal-title":"Plos Pathog"},{"key":"10.1016\/j.wneu.2025.124775_bib4","doi-asserted-by":"crossref","DOI":"10.3390\/microorganisms9102177","article-title":"What do we know about candida auris? State of the art, knowledge gaps, and future directions","volume":"9","author":"Garcia-Bustos","year":"2021","journal-title":"Microorganisms"},{"key":"10.1016\/j.wneu.2025.124775_bib5","doi-asserted-by":"crossref","DOI":"10.3390\/microorganisms12050927","article-title":"Candida auris outbreaks: current status and future perspectives","volume":"12","author":"De Gaetano","year":"2024","journal-title":"Microorganisms"},{"key":"10.1016\/j.wneu.2025.124775_bib6","doi-asserted-by":"crossref","DOI":"10.1093\/femspd\/ftaa034","article-title":"Candida auris: a fungus with identity crisis","volume":"78","author":"Vila","year":"2020","journal-title":"Pathog Dis"},{"key":"10.1016\/j.wneu.2025.124775_bib7","first-page":"323","article-title":"Candida auris: the new fungal threat","volume":"31","author":"Pallotta","year":"2023","journal-title":"Infez Med"},{"key":"10.1016\/j.wneu.2025.124775_bib8","article-title":"Cerebrospinal drain infection by Candida auris: a case report and review of the literature","volume":"10","author":"Halioti","year":"2024","journal-title":"J Fungi (Basel)"},{"key":"10.1016\/j.wneu.2025.124775_bib9","doi-asserted-by":"crossref","first-page":"84","DOI":"10.1016\/j.riam.2021.03.004","article-title":"AmBisome, tres retos: infecci\u00f3n por Candida auris, infecci\u00f3n del sistema nervioso central e infecci\u00f3n asociada a biopel\u00edculas","volume":"38","author":"Ruiz-Gait\u00e1n","year":"2021","journal-title":"Rev Iberoam Micol"},{"key":"10.1016\/j.wneu.2025.124775_bib10","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1016\/j.mmcr.2018.08.005","article-title":"Successful treatment of C. auris shunt infection with intraventricular caspofungin","volume":"22","author":"Singhal","year":"2018","journal-title":"Med Mycol Case Rep"},{"key":"10.1016\/j.wneu.2025.124775_bib11","doi-asserted-by":"crossref","first-page":"149","DOI":"10.4103\/mamcjms.mamcjms_35_18","article-title":"Ventriculoperitoneal shunt-associated meningitis caused by Candida auris: a case report","volume":"4","author":"Chawla","year":"2018","journal-title":"MAMC J Med Sci"},{"key":"10.1016\/j.wneu.2025.124775_bib12","doi-asserted-by":"crossref","first-page":"467","DOI":"10.7326\/M18-0850","article-title":"PRISMA extension for scoping reviews (PRISMA-ScR): checklist and explanation","volume":"169","author":"Tricco","year":"2018","journal-title":"Ann Intern Med"},{"key":"10.1016\/j.wneu.2025.124775_bib13","doi-asserted-by":"crossref","first-page":"2119","DOI":"10.11124\/JBIES-20-00167","article-title":"Updated methodological guidance for the conduct of scoping reviews","volume":"18","author":"Peters","year":"2020","journal-title":"JBI Evid Synth"},{"key":"10.1016\/j.wneu.2025.124775_bib14","doi-asserted-by":"crossref","DOI":"10.1097\/01.ccm.0001000268.74218.2b","article-title":"523: intrathecal caspofungin: a last resort therapy for resistant candida auris ventriculitis","volume":"52","author":"Bashall","year":"2024","journal-title":"Crit Care Med"},{"key":"10.1016\/j.wneu.2025.124775_bib15","article-title":"Beware of candida auris: an emerging fungal pathogen that made its way into Mississippi","volume":"35","author":"Brar HSN","year":"2020","journal-title":"J Gen Intern Med"},{"key":"10.1016\/j.wneu.2025.124775_bib16","article-title":"Successful treatment of Candida auris Ventriculitis with intravenous liposomal Amphotericin B and oral flucytosine: a case report","volume":"12","author":"Kang","year":"2025","journal-title":"Open Forum Infect Dis"},{"key":"10.1016\/j.wneu.2025.124775_bib17","doi-asserted-by":"crossref","first-page":"409","DOI":"10.1016\/j.jinf.2019.02.004","article-title":"Neurosurgical device-associated infections due to Candida auris - three cases from a single tertiary center","volume":"78","author":"Khatamzas","year":"2019","journal-title":"J Infect"},{"key":"10.1016\/j.wneu.2025.124775_bib18","doi-asserted-by":"crossref","first-page":"167","DOI":"10.14192\/kjicp.2023.28.1.167","article-title":"Infection of the cavernous sinus caused by Candida Auris","volume":"28","author":"Lee","year":"2023","journal-title":"Korean J Healthc Assoc Infect Control Prev"},{"key":"10.1016\/j.wneu.2025.124775_bib19","doi-asserted-by":"crossref","DOI":"10.1016\/j.ijmmb.2024.100555","article-title":"Challenges in management of Candida auris meningitis secondary to infected ventriculoperitoneal shunt - a case report","volume":"48","author":"Sridharan","year":"2024","journal-title":"Indian J Med Microbiol"},{"key":"10.1016\/j.wneu.2025.124775_bib20","doi-asserted-by":"crossref","first-page":"818","DOI":"10.1038\/s41579-023-00960-9","article-title":"The rapid emergence of antifungal-resistant human-pathogenic fungi","volume":"21","author":"Lockhart","year":"2023","journal-title":"Nat Rev Microbiol"},{"key":"10.1016\/j.wneu.2025.124775_bib21","doi-asserted-by":"crossref","first-page":"1347","DOI":"10.1007\/s00701-011-0990-9","article-title":"Candida infection of the central nervous system following neurosurgery: a 12-year review","volume":"153","author":"O'Brien","year":"2011","journal-title":"Acta Neurochir (Wien)"},{"key":"10.1016\/j.wneu.2025.124775_bib22","doi-asserted-by":"crossref","DOI":"10.1128\/CMR.00029-17","article-title":"Candida auris: a Review of the Literature","volume":"31","author":"Jeffery-Smith","year":"2018","journal-title":"Clin Microbiol Rev"},{"key":"10.1016\/j.wneu.2025.124775_bib23","doi-asserted-by":"crossref","first-page":"e753","DOI":"10.1093\/cid\/ciaa1462","article-title":"Factors associated with Candida auris colonization and transmission in skilled nursing facilities with ventilator units, New York, 2016-2018","volume":"72","author":"Rossow","year":"2021","journal-title":"Clin Infect Dis"},{"key":"10.1016\/j.wneu.2025.124775_bib24","doi-asserted-by":"crossref","first-page":"387","DOI":"10.5530\/jyp.20251356","article-title":"Assessing the impact of broad-spectrum antibiotics on fungal infection rates in ICU patients: implications for patient safety","volume":"17","author":"Hadia","year":"2025","journal-title":"J Young Pharm"},{"key":"10.1016\/j.wneu.2025.124775_bib25","doi-asserted-by":"crossref","first-page":"138","DOI":"10.3389\/fcimb.2019.00138","article-title":"Exploring the \"Multiple-Hit Hypothesis\" of neurodegenerative disease: bacterial infection comes up to bat","volume":"9","author":"Patrick","year":"2019","journal-title":"Front Cell Infect Microbiol"},{"key":"10.1016\/j.wneu.2025.124775_bib26","doi-asserted-by":"crossref","first-page":"1597","DOI":"10.1056\/NEJMra2311057","article-title":"Cryptococcal disease in diverse hosts","volume":"390","author":"Meya","year":"2024","journal-title":"N Engl J Med"},{"key":"10.1016\/j.wneu.2025.124775_bib27","doi-asserted-by":"crossref","first-page":"362","DOI":"10.1016\/S1474-4422(18)30030-9","article-title":"Advances in the diagnosis and treatment of fungal infections of the CNS","volume":"17","author":"Schwartz","year":"2018","journal-title":"Lancet Neurol"},{"key":"10.1016\/j.wneu.2025.124775_bib28","doi-asserted-by":"crossref","first-page":"e34","DOI":"10.1093\/cid\/ciw861","article-title":"2017 infectious diseases Society of America\u2019s Clinical Practice Guidelines for healthcare-associated ventriculitis and Meningitis\u2217","volume":"64","author":"Tunkel","year":"2017","journal-title":"Clin Infect Dis"},{"key":"10.1016\/j.wneu.2025.124775_bib29","doi-asserted-by":"crossref","first-page":"266","DOI":"10.1093\/mmy\/myaa051","article-title":"Central nervous system candidiasis beyond neonates: lessons from a nationwide study","volume":"59","author":"Chaussade","year":"2021","journal-title":"Med Mycol"},{"key":"10.1016\/j.wneu.2025.124775_bib30","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1016\/0002-9343(83)90084-0","article-title":"Detection of fungi in cerebrospinal fluid","volume":"75","author":"McGinnis","year":"1983","journal-title":"Am J Med"},{"key":"10.1016\/j.wneu.2025.124775_bib31","doi-asserted-by":"crossref","first-page":"11362","DOI":"10.21037\/apm-21-2577","article-title":"Candida central nervous system infection after neurosurgery: a single-institution case series and literature review","volume":"10","author":"Chen","year":"2021","journal-title":"Ann Palliat Med"},{"key":"10.1016\/j.wneu.2025.124775_bib32","doi-asserted-by":"crossref","first-page":"74","DOI":"10.1093\/mmy\/myaa035","article-title":"Challenging diagnosis of chronic cerebral fungal infection: value of (1\u21923)-\u00df-D-glucan and mannan antigen testing in cerebrospinal fluid and of cerebral ventricle puncture","volume":"59","author":"Hobson","year":"2021","journal-title":"Med Mycol"},{"key":"10.1016\/j.wneu.2025.124775_bib33","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1111\/1469-0691.12210","article-title":"Evaluation of two matrix-assisted laser desorption ionization-time of flight mass spectrometry (MALDI-TOF MS) systems for the identification of Candida species","volume":"20","author":"Lacroix","year":"2014","journal-title":"Clin Microbiol Infect"},{"key":"10.1016\/j.wneu.2025.124775_bib34","doi-asserted-by":"crossref","first-page":"e1","DOI":"10.1093\/cid\/civ933","article-title":"Clinical Practice Guideline for the management of candidiasis: 2016 update by the infectious diseases Society of America","volume":"62","author":"Pappas","year":"2016","journal-title":"Clin Infect Dis"},{"key":"10.1016\/j.wneu.2025.124775_bib35","doi-asserted-by":"crossref","DOI":"10.1128\/AAC.01626-19","article-title":"Amphotericin B penetrates into the central nervous system through focal disruption of the blood brain barrier in experimental hematogenous Candida Meningoencephalitis","volume":"63","author":"Petraitis","year":"2019","journal-title":"Antimicrob Agents Chemother"},{"key":"10.1016\/j.wneu.2025.124775_bib36","doi-asserted-by":"crossref","DOI":"10.3389\/fchem.2021.782131","article-title":"Sensitive LC-MS\/MS methods for Amphotericin B analysis in cerebrospinal fluid, plasma, plasma Ultrafiltrate, and urine: application to clinical pharmacokinetics","volume":"9","author":"Pippa","year":"2021","journal-title":"Front Chem"},{"key":"10.1016\/j.wneu.2025.124775_bib37","doi-asserted-by":"crossref","first-page":"891","DOI":"10.1093\/jac\/dkx480","article-title":"A multicentre study of antifungal susceptibility patterns among 350 Candida auris isolates (2009\u201317) in India: role of the ERG11 and FKS1 genes in azole and echinocandin resistance","volume":"73","author":"Chowdhary","year":"2018","journal-title":"J Antimicrob Chemother"},{"key":"10.1016\/j.wneu.2025.124775_bib38","doi-asserted-by":"crossref","first-page":"134","DOI":"10.1093\/cid\/ciw691","article-title":"Simultaneous emergence of multidrug-resistant Candida auris on 3 continents confirmed by whole-genome sequencing and epidemiological analyses","volume":"64","author":"Lockhart","year":"2016","journal-title":"Clin Infect Dis"},{"key":"10.1016\/j.wneu.2025.124775_bib39","doi-asserted-by":"crossref","DOI":"10.1128\/JCM.00007-19","article-title":"Insights into the unique Nature of the East Asian clade of the emerging pathogenic yeast Candida auris","volume":"57","author":"Welsh","year":"2019","journal-title":"J Clin Microbiol"},{"key":"10.1016\/j.wneu.2025.124775_bib40","doi-asserted-by":"crossref","first-page":"1022","DOI":"10.15585\/mmwr.mm7029a2","article-title":"Notes from the field: transmission of pan-resistant and echinocandin-resistant Candida auris in health care facilities - texas and the District of Columbia, January-April 2021","volume":"70","author":"Lyman","year":"2021","journal-title":"MMWR Morb Mortal Wkly Rep"},{"key":"10.1016\/j.wneu.2025.124775_bib41","article-title":"Perspectives on the use of echinocandins in the neonatal intensive care unit","volume":"13","author":"Dermitzaki","year":"2024","journal-title":"Antibiotics (Basel)"},{"key":"10.1016\/j.wneu.2025.124775_bib42","doi-asserted-by":"crossref","DOI":"10.1128\/AAC.01056-17","article-title":"In vitro interactions of echinocandins with triazoles against multidrug-resistant Candida auris","volume":"61","author":"Fakhim","year":"2017","journal-title":"Antimicrob Agents Chemother"}],"container-title":["World Neurosurgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1878875025011325?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1878875025011325?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,6,19]],"date-time":"2026-06-19T08:28:04Z","timestamp":1781857684000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1878875025011325"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,2]]},"references-count":42,"alternative-id":["S1878875025011325"],"URL":"https:\/\/doi.org\/10.1016\/j.wneu.2025.124775","relation":{},"ISSN":["1878-8750"],"issn-type":[{"value":"1878-8750","type":"print"}],"subject":[],"published":{"date-parts":[[2026,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Intracranial Candida Auris Infection: A Case Report and Scoping Review","name":"articletitle","label":"Article Title"},{"value":"World Neurosurgery","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.wneu.2025.124775","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 The Authors. Published by Elsevier Inc.","name":"copyright","label":"Copyright"}],"article-number":"124775"}}