{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T20:59:46Z","timestamp":1791233986127,"version":"4.1.0"},"reference-count":27,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,3,16]],"date-time":"2026-03-16T00:00:00Z","timestamp":1773619200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["World Neurosurgery"],"published-print":{"date-parts":[[2026,6]]},"DOI":"10.1016\/j.wneu.2026.124926","type":"journal-article","created":{"date-parts":[[2026,3,18]],"date-time":"2026-03-18T17:29:58Z","timestamp":1773854998000},"page":"124926","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"C","title":["Lumbar Spinal Stenosis in Patients with Acromegaly: An MRI-Based Case-Control Study"],"prefix":"10.1016","volume":"210","author":[{"given":"Tong","family":"Niu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaopeng","family":"Guo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yanyan","family":"Bian","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bing","family":"Xing","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yipeng","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jianguo","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.wneu.2026.124926_bib1","doi-asserted-by":"crossref","first-page":"3933","DOI":"10.1210\/jc.2014-2700","article-title":"Acromegaly: an Endocrine Society Clinical Practice Guideline","volume":"99","author":"Katznelson","year":"2014","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1016\/j.wneu.2026.124926_bib2","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1007\/s11102-013-0464-6","article-title":"Increased clinical symptoms of acromegalic arthropathy in patients with long-term disease control: a prospective follow-up study","volume":"17","author":"Claessen","year":"2014","journal-title":"Pituitary"},{"key":"10.1016\/j.wneu.2026.124926_bib3","doi-asserted-by":"crossref","first-page":"552","DOI":"10.1007\/s11102-019-00966-8","article-title":"Arthropathy in acromegaly: a questionnaire-based estimation of motor disability and its relation with quality of life and work productivity","volume":"22","author":"Fatti","year":"2019","journal-title":"Pituitary"},{"key":"10.1016\/j.wneu.2026.124926_bib4","doi-asserted-by":"crossref","first-page":"713","DOI":"10.1016\/j.rdc.2010.09.004","article-title":"Arthropathy in acromegaly","volume":"36","author":"Killinger","year":"2010","journal-title":"Rheum Dis Clin North Am"},{"key":"10.1016\/j.wneu.2026.124926_bib5","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1530\/EJE-08-0845","article-title":"High prevalence of arthropathy, according to the definitions of radiological and clinical osteoarthritis, in patients with long-term cure of acromegaly: a case\u2013control study","volume":"160","author":"Wassenaar","year":"2009","journal-title":"Eur J Endocrinol"},{"key":"10.1016\/j.wneu.2026.124926_bib6","doi-asserted-by":"crossref","first-page":"320","DOI":"10.1136\/ard.2010.131698","article-title":"Arthropathy in long-term cured acromeagaly is characterised by osteophytes without joint space narrowing: a comparison with generalised osteoarthritis","volume":"70","author":"Wassenaar","year":"2011","journal-title":"Ann Rheum Dis"},{"key":"10.1016\/j.wneu.2026.124926_bib7","doi-asserted-by":"crossref","first-page":"622","DOI":"10.1007\/s11102-022-01233-z","article-title":"Clinical and radiographic assessment of peripheral joints in controlled acromegaly","volume":"25","author":"Pelsma","year":"2022","journal-title":"Pituitary"},{"key":"10.1016\/j.wneu.2026.124926_bib8","doi-asserted-by":"crossref","DOI":"10.1136\/bcr-2024-262123","article-title":"Cervical osteophyte complex causing compressive myelopathy leading to a diagnosis of acromegaly","volume":"18","author":"Lalwani","year":"2025","journal-title":"BMJ Case Rep"},{"key":"10.1016\/j.wneu.2026.124926_bib9","doi-asserted-by":"crossref","first-page":"598","DOI":"10.1210\/jc.2003-031283","article-title":"Acromegalic axial arthropathy: a clinical case-control study","volume":"89","author":"Scarpa","year":"2004","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1016\/j.wneu.2026.124926_bib10","doi-asserted-by":"crossref","first-page":"2093","DOI":"10.2169\/internalmedicine.0763-22","article-title":"Lumbar spinal canal stenosis in acromegaly: a case report and literature review","volume":"62","author":"Yoshizawa","year":"2022","journal-title":"Intern Med"},{"key":"10.1016\/j.wneu.2026.124926_bib11","doi-asserted-by":"crossref","first-page":"145","DOI":"10.3171\/jns.1982.56.1.0145","article-title":"Acromegaly and spinal stenosis. Case report","volume":"56","author":"Epstein","year":"1982","journal-title":"J Neurosurg"},{"key":"10.1016\/j.wneu.2026.124926_bib12","doi-asserted-by":"crossref","first-page":"1033","DOI":"10.1007\/s00256-011-1102-x","article-title":"A new grading system of lumbar central canal stenosis on MRI: an easy and reliable method","volume":"40","author":"Guen","year":"2011","journal-title":"Skeletal Radiol"},{"key":"10.1016\/j.wneu.2026.124926_bib13","doi-asserted-by":"crossref","first-page":"1095","DOI":"10.2214\/AJR.09.2772","article-title":"A practical MRI grading system for lumbar foraminal stenosis","volume":"194","author":"Lee","year":"2010","journal-title":"AJR Am J Roentgenol"},{"key":"10.1016\/j.wneu.2026.124926_bib14","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1186\/1471-2474-12-175","article-title":"Quantitative radiologic criteria for the diagnosis of lumbar spinal stenosis: a systematic literature review","volume":"12","author":"Steurer","year":"2011","journal-title":"BMC Musculoskelet Disord"},{"key":"10.1016\/j.wneu.2026.124926_bib15","doi-asserted-by":"crossref","first-page":"775","DOI":"10.1159\/000511811","article-title":"Vertebral fractures associated with spinal sagittal imbalance and quality of life in acromegaly: a radiographic study with EOS 2D\/3D technology","volume":"111","author":"Cellini","year":"2021","journal-title":"Neuroendocrinology"},{"key":"10.1016\/j.wneu.2026.124926_bib16","doi-asserted-by":"crossref","first-page":"601","DOI":"10.1007\/s11102-019-00991-7","article-title":"The acromegalic spine: fractures, deformities and spinopelvic balance","volume":"22","author":"de Azevedo Oliveira","year":"2019","journal-title":"Pituitary"},{"key":"10.1016\/j.wneu.2026.124926_bib17","doi-asserted-by":"crossref","first-page":"86","DOI":"10.1159\/000375450","article-title":"Bone and joint disorders in acromegaly","volume":"103","author":"Claessen","year":"2016","journal-title":"Neuroendocrinology"},{"key":"10.1016\/j.wneu.2026.124926_bib18","doi-asserted-by":"crossref","first-page":"2087","DOI":"10.1007\/s40618-025-02619-z","article-title":"Evaluation of bone density and microstructure by DXA, TBS and HR-pQCT: an assessment of cortical porosity and its association with vertebral fractures in patients with acromegaly","volume":"48","author":"Ornellas","year":"2025","journal-title":"J Endocrinol Invest"},{"key":"10.1016\/j.wneu.2026.124926_bib19","doi-asserted-by":"crossref","first-page":"734","DOI":"10.1016\/j.spinee.2012.11.059","article-title":"An evidence-based clinical guideline for the diagnosis and treatment of degenerative lumbar spinal stenosis (update)","volume":"13","author":"Kreiner","year":"2013","journal-title":"Spine J"},{"key":"10.1016\/j.wneu.2026.124926_bib20","doi-asserted-by":"crossref","first-page":"353","DOI":"10.1186\/s12891-021-04232-6","article-title":"Acromegaly presenting with myelopathy due to ossification of posterior longitudinal ligament: a case report","volume":"22","author":"Kamakura","year":"2021","journal-title":"BMC Musculoskelet Disord"},{"key":"10.1016\/j.wneu.2026.124926_bib21","doi-asserted-by":"crossref","first-page":"2143","DOI":"10.1007\/s00586-020-06339-1","article-title":"Prevalence of lumbar spinal stenosis in general and clinical populations: a systematic review and meta-analysis","volume":"29","author":"Jensen","year":"2020","journal-title":"Eur Spine J"},{"key":"10.1016\/j.wneu.2026.124926_bib22","doi-asserted-by":"crossref","first-page":"1103","DOI":"10.1016\/j.joca.2012.06.018","article-title":"Prevalence of symptomatic lumbar spinal stenosis and its association with physical performance in a population-based cohort in Japan: the Wakayama spine study","volume":"20","author":"Ishimoto","year":"2012","journal-title":"Osteoarthritis Cartilage"},{"key":"10.1016\/j.wneu.2026.124926_bib23","article-title":"Management of lumbar spinal stenosis","volume":"352","author":"Lurie","year":"2016","journal-title":"BMJ"},{"key":"10.1016\/j.wneu.2026.124926_bib24","doi-asserted-by":"crossref","first-page":"779","DOI":"10.1530\/EJE-16-1073","article-title":"Acromegalic arthropathy in various stages of the disease: an MRI study","volume":"176","author":"Claessen","year":"2017","journal-title":"Eur J Endocrinol"},{"key":"10.1016\/j.wneu.2026.124926_bib25","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1159\/000491729","article-title":"Locally produced IGF-1 promotes hypertrophy of the ligamentum flavum via the mTORC1 signaling pathway","volume":"48","author":"Yan","year":"2018","journal-title":"Cell Physiol Biochem"},{"key":"10.1016\/j.wneu.2026.124926_bib26","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1530\/EJE-12-0147","article-title":"Progression of acromegalic arthropathy despite long-term biochemical control: a prospective, radiological study","volume":"167","author":"Claessen","year":"2012","journal-title":"Eur J Endocrinol"},{"key":"10.1016\/j.wneu.2026.124926_bib27","doi-asserted-by":"crossref","first-page":"188","DOI":"10.1210\/clinem\/dgaa747","article-title":"Progression of acromegalic arthropathy in long-term controlled acromegaly patients: 9 years of longitudinal follow-up","volume":"106","author":"Pelsma","year":"2021","journal-title":"J Clin Endocrinol Metab"}],"container-title":["World Neurosurgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1878875026001427?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1878875026001427?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T20:28:43Z","timestamp":1791232123000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1878875026001427"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,6]]},"references-count":27,"alternative-id":["S1878875026001427"],"URL":"https:\/\/doi.org\/10.1016\/j.wneu.2026.124926","relation":{},"ISSN":["1878-8750"],"issn-type":[{"value":"1878-8750","type":"print"}],"subject":[],"published":{"date-parts":[[2026,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Lumbar Spinal Stenosis in Patients with Acromegaly: An MRI-Based Case-Control Study","name":"articletitle","label":"Article Title"},{"value":"World Neurosurgery","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.wneu.2026.124926","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 The Authors. Published by Elsevier Inc.","name":"copyright","label":"Copyright"}],"article-number":"124926"}}