{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,12]],"date-time":"2026-10-12T20:30:14Z","timestamp":1791837014857,"version":"4.3.4"},"reference-count":38,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T00:00:00Z","timestamp":1788220800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T00:00:00Z","timestamp":1788220800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,7,17]],"date-time":"2026-07-17T00:00:00Z","timestamp":1784246400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["World Neurosurgery"],"published-print":{"date-parts":[[2026,9]]},"DOI":"10.1016\/j.wneu.2026.125204","type":"journal-article","created":{"date-parts":[[2026,7,23]],"date-time":"2026-07-23T15:31:19Z","timestamp":1784820679000},"page":"125204","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":1,"special_numbering":"C","title":["Anatomical and Temporal Blind Spots Explain the High False-Negative Rate of Motor Evoked Potential Monitoring in Glioma Surgery: A Single-Center Analysis of 106 Consecutive Patients"],"prefix":"10.1016","volume":"213","author":[{"ORCID":"https:\/\/orcid.org\/0009-0001-4830-6274","authenticated-orcid":false,"given":"Hui","family":"Zhou","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xudong","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wanqi","family":"Luo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0001-3324-2255","authenticated-orcid":false,"given":"Xin","family":"Liao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.wneu.2026.125204_bib1","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1016\/B978-0-12-819826-1.00013-2","article-title":"Intraoperative mapping and monitoring during brain tumor surgeries","volume":"186","author":"Seidel","year":"2022","journal-title":"Handb Clin Neurol"},{"key":"10.1016\/j.wneu.2026.125204_bib2","doi-asserted-by":"crossref","first-page":"2559","DOI":"10.1200\/JCO.2011.38.4818","article-title":"Impact of intraoperative stimulation brain mapping on glioma surgery outcome: a meta-analysis","volume":"30","author":"De Witt Hamer","year":"2012","journal-title":"J Clin Oncol"},{"key":"10.1016\/j.wneu.2026.125204_bib3","doi-asserted-by":"crossref","first-page":"582","DOI":"10.3171\/jns.2007.106.4.582","article-title":"Motor tract monitoring during insular glioma surgery","volume":"106","author":"Neuloh","year":"2007","journal-title":"J Neurosurg"},{"key":"10.1016\/j.wneu.2026.125204_bib4","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1097\/WNP.0000000000000227","article-title":"Prognostic values of motor evoked potentials in insular, precental, or postcentral resections","volume":"33","author":"Boex","year":"2016","journal-title":"J Clin Neurophysiol"},{"key":"10.1016\/j.wneu.2026.125204_bib5","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1007\/s11060-022-04229-8","article-title":"Short and long-term prognostic value of intraoperative motor evoked potentials in brain tumor patients: a case series of 121 brain tumor patients","volume":"161","author":"Silverstein","year":"2023","journal-title":"J Neurooncol"},{"key":"10.1016\/j.wneu.2026.125204_bib6","doi-asserted-by":"crossref","first-page":"1060","DOI":"10.1227\/NEU.0b013e31823f5ade","article-title":"Predictive value and safety of intraoperative neurophysiological monitoring with motor evoked potentials in glioma surgery","volume":"70","author":"Krieg","year":"2012","journal-title":"Neurosurgery"},{"key":"10.1016\/j.wneu.2026.125204_bib7","doi-asserted-by":"crossref","first-page":"829","DOI":"10.3171\/2013.5.JNS121981","article-title":"Postoperative ischemic changes after glioma resection identified by diffusion-weighted magnetic resonance imaging and their association with intraoperative motor evoked potentials","volume":"119","author":"Gempt","year":"2013","journal-title":"J Neurosurg"},{"key":"10.1016\/j.wneu.2026.125204_bib8","doi-asserted-by":"crossref","first-page":"768","DOI":"10.1093\/neuros\/nyx554","article-title":"The impact of diffusion tensor imaging fiber tracking of the corticospinal tract based on navigated transcranial magnetic stimulation on surgery of motor-eloquent brain lesions","volume":"83","author":"Raffa","year":"2018","journal-title":"Neurosurgery"},{"key":"10.1016\/j.wneu.2026.125204_bib9","doi-asserted-by":"crossref","first-page":"419","DOI":"10.1007\/s00701-024-06308-3","article-title":"Preoperative nTMS analysis: a sensitive tool to detect imminent motor deficits in brain tumor patients","volume":"166","author":"Moritz","year":"2024","journal-title":"Acta Neurochir (Wien)"},{"key":"10.1016\/j.wneu.2026.125204_bib10","doi-asserted-by":"crossref","first-page":"795","DOI":"10.3171\/2015.8.JNS151439","article-title":"A novel threshold criterion in transcranial motor evoked potentials during surgery for gliomas close to the motor pathway","volume":"125","author":"Abboud","year":"2016","journal-title":"J Neurosurg"},{"key":"10.1016\/j.wneu.2026.125204_bib11","doi-asserted-by":"crossref","DOI":"10.3389\/fonc.2022.963669","article-title":"Transcranial versus direct electrical stimulation for intraoperative motor-evoked potential monitoring: prognostic value comparison in asleep brain tumor surgery","volume":"12","author":"Vigan\u00f2","year":"2022","journal-title":"Front Oncol"},{"key":"10.1016\/j.wneu.2026.125204_bib12","doi-asserted-by":"crossref","DOI":"10.3389\/fonc.2021.676626","article-title":"Preoperative nTMS and intraoperative neurophysiology - a comparative analysis in patients with motor-eloquent glioma","volume":"11","author":"Rosenstock","year":"2021","journal-title":"Front Oncol"},{"key":"10.1016\/j.wneu.2026.125204_bib13","doi-asserted-by":"crossref","first-page":"2291","DOI":"10.1016\/j.clinph.2013.07.025","article-title":"Intraoperative motor evoked potential monitoring\u2013a position statement by the American Society of Neurophysiological Monitoring","volume":"124","author":"Macdonald","year":"2013","journal-title":"Clin Neurophysiol"},{"key":"10.1016\/j.wneu.2026.125204_bib14","doi-asserted-by":"crossref","first-page":"593","DOI":"10.3171\/jns.2007.106.4.593","article-title":"Clinical impact of integrated functional neuronavigation and subcortical electrical stimulation to preserve motor function during resection of brain tumors","volume":"106","author":"Mikuni","year":"2007","journal-title":"J Neurosurg"},{"key":"10.1016\/j.wneu.2026.125204_bib15","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1146\/annurev.ne.09.030186.002041","article-title":"Parallel organization of functionally segregated circuits linking basal ganglia and cortex","volume":"9","author":"Alexander","year":"1986","journal-title":"Annu Rev Neurosci"},{"key":"10.1016\/j.wneu.2026.125204_bib16","doi-asserted-by":"crossref","first-page":"750","DOI":"10.1038\/nn1075","article-title":"Non-invasive mapping of connections between human thalamus and cortex using diffusion imaging","volume":"6","author":"Behrens","year":"2003","journal-title":"Nat Neurosci"},{"key":"10.1016\/j.wneu.2026.125204_bib17","doi-asserted-by":"crossref","DOI":"10.1101\/cshperspect.a009621","article-title":"Functional neuroanatomy of the basal ganglia","volume":"2","author":"Lanciego","year":"2012","journal-title":"Cold Spring Harb Perspect Med"},{"key":"10.1016\/j.wneu.2026.125204_bib18","doi-asserted-by":"crossref","first-page":"871","DOI":"10.1212\/WNL.57.5.871","article-title":"Role of the supplementary motor area in motor deficit following medial frontal lobe surgery","volume":"57","author":"Krainik","year":"2001","journal-title":"Neurology"},{"key":"10.1016\/j.wneu.2026.125204_bib19","first-page":"297","article-title":"Somatotopy of the supplementary motor area: evidence from correlation of the extent of surgical resection with the clinical patterns of deficit","volume":"50","author":"Fontaine","year":"2002","journal-title":"Neurosurgery"},{"key":"10.1016\/j.wneu.2026.125204_bib20","doi-asserted-by":"crossref","first-page":"992","DOI":"10.1016\/j.neuroimage.2011.03.022","article-title":"Evidence for potentials and limitations of brain plasticity using an atlas of functional resectability of WHO grade II gliomas: towards a \u201cminimal common brain\u201d","volume":"56","author":"Ius","year":"2011","journal-title":"Neuroimage"},{"key":"10.1016\/j.wneu.2026.125204_bib21","doi-asserted-by":"crossref","DOI":"10.1093\/braincomms\/fcaa226","article-title":"Long-term motor deficit in brain tumour surgery with preserved intra-operative motor-evoked potentials","volume":"3","author":"Giampiccolo","year":"2021","journal-title":"Brain Communications"},{"key":"10.1016\/j.wneu.2026.125204_bib22","first-page":"79","article-title":"Brain surgery in motor areas: the invaluable assistance of intraoperative neurophysiological monitoring","volume":"47","author":"Sala","year":"2003","journal-title":"J Neurosurg Sci"},{"key":"10.1016\/j.wneu.2026.125204_bib23","doi-asserted-by":"crossref","DOI":"10.3171\/2009.8.FOCUS09141","article-title":"Neurophysiological basis of direct cortical stimulation and applied neuroanatomy of the motor cortex: a review","volume":"27","author":"Kombos","year":"2009","journal-title":"Neurosurg Focus"},{"key":"10.1016\/j.wneu.2026.125204_bib24","doi-asserted-by":"crossref","first-page":"263","DOI":"10.3171\/jns.2007.106.2.263","article-title":"Ischemic complications associated with resection of opercular glioma","volume":"106","author":"Kumabe","year":"2007","journal-title":"J Neurosurg"},{"key":"10.1016\/j.wneu.2026.125204_bib25","doi-asserted-by":"crossref","first-page":"825","DOI":"10.3171\/JNS\/2008\/109\/11\/0825","article-title":"Resection of insular gliomas: the importance of lenticulostriate artery position","volume":"109","author":"Moshel","year":"2008","journal-title":"J Neurosurg"},{"key":"10.1016\/j.wneu.2026.125204_bib26","doi-asserted-by":"crossref","first-page":"676","DOI":"10.3171\/jns.2000.92.4.0676","article-title":"Arteries of the insula","volume":"92","author":"T\u00fcre","year":"2000","journal-title":"J Neurosurg"},{"key":"10.1016\/j.wneu.2026.125204_bib27","doi-asserted-by":"crossref","first-page":"E16","DOI":"10.3171\/2014.10.FOCUS14524","article-title":"Intraoperative monopolar mapping during 5-ALA\u2013guided resections of glioblastomas adjacent to motor eloquent areas: evaluation of resection rates and neurological outcome","volume":"37","author":"Schucht","year":"2014","journal-title":"Neurosurg Focus"},{"key":"10.1016\/j.wneu.2026.125204_bib28","doi-asserted-by":"crossref","first-page":"369","DOI":"10.3171\/jns.2004.100.3.0369","article-title":"Intraoperative subcortical stimulation mapping for hemispheric perirolandic gliomas located within or adjacent to the descending motor pathways: evaluation of morbidity and assessment of functional outcome in 294 patients","volume":"100","author":"Keles","year":"2004","journal-title":"J Neurosurg"},{"key":"10.1016\/j.wneu.2026.125204_bib29","doi-asserted-by":"crossref","first-page":"581","DOI":"10.1227\/NEU.0b013e3182181b89","article-title":"Preoperative functional mapping for rolandic brain tumor surgery: comparison of navigated transcranial magnetic stimulation to direct cortical stimulation","volume":"69","author":"Picht","year":"2011","journal-title":"Neurosurgery"},{"key":"10.1016\/j.wneu.2026.125204_bib30","doi-asserted-by":"crossref","first-page":"369","DOI":"10.1016\/j.neuroimage.2007.08.031","article-title":"Motor and language DTI fiber tracking combined with intraoperative subcortical mapping for surgical removal of gliomas","volume":"39","author":"Bello","year":"2008","journal-title":"Neuroimage"},{"key":"10.1016\/j.wneu.2026.125204_bib31","doi-asserted-by":"crossref","first-page":"476","DOI":"10.1016\/S1474-4422(05)70140-X","article-title":"Lessons from brain mapping in surgery for low-grade glioma: insights into associations between tumour and brain plasticity","volume":"4","author":"Duffau","year":"2005","journal-title":"Lancet Neurol"},{"key":"10.1016\/j.wneu.2026.125204_bib32","doi-asserted-by":"crossref","DOI":"10.1016\/j.wneu.2025.124185","article-title":"A prewarning signalling in motor evoked potentials monitoring for Insular glioma surgery: a preliminary study","volume":"200","author":"Bonaudo","year":"2025","journal-title":"World Neurosurg"},{"key":"10.1016\/j.wneu.2026.125204_bib33","doi-asserted-by":"crossref","first-page":"2803","DOI":"10.3390\/cancers13112803","article-title":"Motor evoked potential warning criteria in supratentorial surgery: a scoping review","volume":"13","author":"Asimakidou","year":"2021","journal-title":"Cancers (Basel)"},{"key":"10.1016\/j.wneu.2026.125204_bib34","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1016\/j.jocn.2018.08.019","article-title":"Intraoperative monitoring of motor-evoked potential for parenchymal brain tumor removal: an analysis of false-negative cases","volume":"57","author":"Umemura","year":"2018","journal-title":"J Clin Neurosci"},{"key":"10.1016\/j.wneu.2026.125204_bib35","first-page":"171","article-title":"Are there false-negative results of motor evoked potential monitoring in brain surgery? Central European Neurosurgery-Zentralblatt f\u00fcr","volume":"70","author":"Neuloh","year":"2009","journal-title":"Neurochirurgie"},{"key":"10.1016\/j.wneu.2026.125204_bib36","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1227\/01.NEU.0000249206.58601.DE","article-title":"Intraoperative subcortical languagetract mapping guides surgical removalof gliomas involving speech areas","volume":"60","author":"Bello","year":"2007","journal-title":"Neurosurgery"},{"key":"10.1016\/j.wneu.2026.125204_bib37","doi-asserted-by":"crossref","first-page":"E7","DOI":"10.3171\/2009.12.FOCUS09237","article-title":"Intraoperative electrical stimulation in awake craniotomy: methodological aspects of current practice","volume":"28","author":"Szel\u00e9nyi","year":"2010","journal-title":"Neurosurg Focus"},{"key":"10.1016\/j.wneu.2026.125204_bib38","doi-asserted-by":"crossref","first-page":"859","DOI":"10.1093\/brain\/117.4.859","article-title":"The behavioural and motor consequences of focal lesions of the basal ganglia in man","volume":"117","author":"Bhatia","year":"1994","journal-title":"Brain"}],"container-title":["World Neurosurgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1878875026004201?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1878875026004201?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,9,17]],"date-time":"2026-09-17T08:48:24Z","timestamp":1789634904000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1878875026004201"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,9]]},"references-count":38,"alternative-id":["S1878875026004201"],"URL":"https:\/\/doi.org\/10.1016\/j.wneu.2026.125204","relation":{},"ISSN":["1878-8750"],"issn-type":[{"value":"1878-8750","type":"print"}],"subject":[],"published":{"date-parts":[[2026,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Anatomical and Temporal Blind Spots Explain the High False-Negative Rate of Motor Evoked Potential Monitoring in Glioma Surgery: A Single-Center Analysis of 106 Consecutive Patients","name":"articletitle","label":"Article Title"},{"value":"World Neurosurgery","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.wneu.2026.125204","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 The Author(s). Published by Elsevier Inc.","name":"copyright","label":"Copyright"}],"article-number":"125204"}}