{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T14:27:22Z","timestamp":1792074442377,"version":"4.4.0"},"reference-count":43,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2024,2,1]],"date-time":"2024-02-01T00:00:00Z","timestamp":1706745600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,2,1]],"date-time":"2024-02-01T00:00:00Z","timestamp":1706745600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2023,10,19]],"date-time":"2023-10-19T00:00:00Z","timestamp":1697673600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100019375","name":"Universitas Udayana","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100019375","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100017094","name":"Department of Internal Medicine, University of Utah","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100017094","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["AJOG Global Reports"],"published-print":{"date-parts":[[2024,2]]},"DOI":"10.1016\/j.xagr.2023.100285","type":"journal-article","created":{"date-parts":[[2023,10,26]],"date-time":"2023-10-26T11:49:00Z","timestamp":1698320940000},"page":"100285","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":7,"title":["The role of probiotics and synbiotics on treatment of gestational diabetes: systematic review and meta-analysis"],"prefix":"10.1016","volume":"4","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3474-5647","authenticated-orcid":false,"given":"Arresta Vitasatria","family":"Suastika","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"I Gde Raka","family":"Widiana","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ni Nengah Dwi","family":"Fatmawati","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ketut","family":"Suastika","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ivana Beatrice","family":"Paulus","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"I Nengah","family":"Sujaya","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.xagr.2023.100285_bib0001","unstructured":"World Health Organization. Diagnostic criteria and classification of hyperglycaemia first detected in pregnancy. Available at: https:\/\/apps.who.int\/iris\/handle\/10665\/85975. Accessed July 20, 2023."},{"key":"10.1016\/j.xagr.2023.100285_bib0002","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1007\/s11892-015-0699-x","article-title":"Prevalence of gestational diabetes and risk of progression to Type 2 diabetes: a global perspective","volume":"16","author":"Zhu","year":"2016","journal-title":"Curr Diab Rep"},{"key":"10.1016\/j.xagr.2023.100285_bib0003","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1038\/s41572-019-0098-8","article-title":"Gestational diabetes mellitus","volume":"5","author":"McIntyre","year":"2019","journal-title":"Nat Rev Dis Primers"},{"key":"10.1016\/j.xagr.2023.100285_bib0004","doi-asserted-by":"crossref","first-page":"417","DOI":"10.1136\/pgmj.2010.109157","article-title":"Diabetes in pregnancy: health risks and management","volume":"87","author":"Ali","year":"2011","journal-title":"Postgrad Med J"},{"key":"10.1016\/j.xagr.2023.100285_bib0005","first-page":"91","article-title":"Impact of fetal reduction on the incidence of gestational diabetes","volume":"99","author":"Sivan","year":"2002","journal-title":"Obstet Gynecol"},{"key":"10.1016\/j.xagr.2023.100285_bib0006","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1177\/2042018815577039","article-title":"The role of adipokines in gestational diabetes mellitus","volume":"6","author":"Al-Badri","year":"2015","journal-title":"Ther Adv Endocrinol Metab"},{"key":"10.1016\/j.xagr.2023.100285_bib0007","unstructured":"food and agriculture organization, World Health Organization. Probiotics in food health and nutritional properties and guidelines for evaluation; 2006. https:\/\/www.fao.org\/3\/a0512e\/a0512e.pdf."},{"key":"10.1016\/j.xagr.2023.100285_bib0008","doi-asserted-by":"crossref","first-page":"1401","DOI":"10.1093\/jn\/125.6.1401","article-title":"Dietary modulation of the human colonic microbiota: introducing the concept of prebiotics","volume":"125","author":"Gibson","year":"1995","journal-title":"J Nutr"},{"key":"10.1016\/j.xagr.2023.100285_bib0009","first-page":"58","article-title":"Health effects of probiotics and prebiotics Aa literature review on human studies","volume":"45","author":"Andersson","year":"2001","journal-title":"Nutr Res"},{"key":"10.1016\/j.xagr.2023.100285_bib0010","doi-asserted-by":"crossref","first-page":"1227","DOI":"10.1007\/s12602-018-9490-z","article-title":"The effects of probiotic supplementation on genetic and metabolic profiles in patients with gestational diabetes mellitus: a randomized, double-blind, placebo-controlled trial","volume":"11","author":"Babadi","year":"2019","journal-title":"Probiotics Antimicrob Proteins"},{"key":"10.1016\/j.xagr.2023.100285_bib0011","doi-asserted-by":"crossref","first-page":"496","DOI":"10.1007\/s12602-017-9313-7","article-title":"The effects of synbiotic supplementation on pregnancy outcomes in gestational diabetes","volume":"10","author":"Karamali","year":"2018","journal-title":"Probiotics Antimicrob Proteins"},{"key":"10.1016\/j.xagr.2023.100285_bib0012","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1186\/s12884-017-1629-5","article-title":"Pregnancy outcomes in women taking probiotics or prebiotics: a systematic review and meta-analysis","volume":"18","author":"Jarde","year":"2018","journal-title":"BMC Pregnancy Childbirth"},{"key":"10.1016\/j.xagr.2023.100285_bib0013","doi-asserted-by":"crossref","first-page":"1499","DOI":"10.1002\/mnfr.201000605","article-title":"Dietary-resistant starch improves maternal glycemic control in Goto-Kakizaki rat","volume":"55","author":"Shen","year":"2011","journal-title":"Mol Nutr Food Res"},{"key":"10.1016\/j.xagr.2023.100285_bib0014","doi-asserted-by":"crossref","first-page":"587","DOI":"10.1016\/j.jand.2018.12.013","article-title":"The effects of prebiotics and substances with prebiotic properties on metabolic and inflammatory biomarkers in individuals with type 2 diabetes mellitus: a systematic review","volume":"120","author":"Colantonio","year":"2020","journal-title":"J Acad Nutr Diet"},{"key":"10.1016\/j.xagr.2023.100285_bib0015","doi-asserted-by":"crossref","first-page":"7577","DOI":"10.1007\/s13197-015-1921-1","article-title":"Probiotics, prebiotics and Synbiotics- a review","volume":"52","author":"Pandey","year":"2015","journal-title":"J Food Sci Technol"},{"key":"10.1016\/j.xagr.2023.100285_bib0016","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1016\/j.diabres.2018.02.008","article-title":"The effects of synbiotic supplementation on insulin resistance\/sensitivity, lipid profile and total antioxidant capacity in women with gestational diabetes mellitus: a randomized double blind placebo controlled clinical trial","volume":"138","author":"Nabhani","year":"2018","journal-title":"Diabetes Res Clin Pract"},{"key":"10.1016\/j.xagr.2023.100285_bib0017","doi-asserted-by":"crossref","first-page":"1128","DOI":"10.1080\/14767058.2017.1310193","article-title":"The effects of probiotic supplementation on biomarkers of inflammation, oxidative stress and pregnancy outcomes in gestational diabetes","volume":"31","author":"Badehnoosh","year":"2018","journal-title":"J Matern Fetal Neonatal Med"},{"key":"10.1016\/j.xagr.2023.100285_bib0018","series-title":"GRADE Handbook. Handbook for grading the quality of evidence and the strength of recommendations using the GRADE approach Guyatt G, Oxman A, eds","year":"2013"},{"key":"10.1016\/j.xagr.2023.100285_bib0019","series-title":"Cochrane Handbook for Systematic Reviews of Interventions","article-title":"Chapter 10. Analysing data and undertaking meta-analyses","author":"Deeks","year":"2022"},{"key":"10.1016\/j.xagr.2023.100285_bib0020","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1111\/jdi.12863","article-title":"Effects of probiotic supplements on insulin resistance in gestational diabetes mellitus: a double-blind randomized controlled trial","volume":"10","author":"Kijmanawat","year":"2019","journal-title":"J Diabetes Investig"},{"key":"10.1016\/j.xagr.2023.100285_bib0021","doi-asserted-by":"crossref","DOI":"10.1155\/2016\/5190846","article-title":"Effects of a multispecies probiotic mixture on glycemic control and inflammatory status in women with gestational diabetes: a randomized controlled clinical trial","volume":"2016","author":"Jafarnejad","year":"2016","journal-title":"J Nutr Metab"},{"key":"10.1016\/j.xagr.2023.100285_bib0022","article-title":"Impact of probiotics in women with gestational diabetes mellitus on metabolic health: a randomized controlled trial","volume":"212","author":"Lindsay","year":"2015","journal-title":"Am J Obstet Gynecol"},{"key":"10.1016\/j.xagr.2023.100285_bib0023","doi-asserted-by":"crossref","first-page":"234","DOI":"10.1016\/j.diabet.2016.04.009","article-title":"Effects of probiotic supplementation on glycaemic control and lipid profiles in gestational diabetes: a randomized, double-blind, placebo-controlled trial","volume":"42","author":"Karamali","year":"2016","journal-title":"Diabetes Metab"},{"key":"10.1016\/j.xagr.2023.100285_bib0024","first-page":"581","article-title":"Effect of probiotic supplements in women with gestational diabetes mellitus on inflammation and oxidative stress biomarkers: a randomized clinical trial","volume":"27","author":"Hajifaraji","year":"2018","journal-title":"Asia Pac J Clin Nutr"},{"key":"10.1016\/j.xagr.2023.100285_bib0025","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1186\/s41043-015-0034-9","article-title":"Is there a value for probiotic supplements in gestational diabetes mellitus? A randomized clinical trial","volume":"33","author":"Dolatkhah","year":"2015","journal-title":"J Health Popul Nutr"},{"key":"10.1016\/j.xagr.2023.100285_bib0026","doi-asserted-by":"crossref","first-page":"1394","DOI":"10.1017\/S0007114516003457","article-title":"The effects of synbiotic supplementation on markers of insulin metabolism and lipid profiles in gestational diabetes: a randomised, double-blind, placebo-controlled trial","volume":"116","author":"Ahmadi","year":"2016","journal-title":"Br J Nutr"},{"key":"10.1016\/j.xagr.2023.100285_bib0027","doi-asserted-by":"crossref","first-page":"2098","DOI":"10.1016\/j.clnu.2018.10.028","article-title":"The effects of vitamin D and probiotic co-supplementation on glucose homeostasis, inflammation, oxidative stress and pregnancy outcomes in gestational diabetes: a randomized, double-blind, placebo-controlled trial","volume":"38","author":"Jamilian","year":"2019","journal-title":"Clin Nutr"},{"key":"10.1016\/j.xagr.2023.100285_bib0028","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1016\/j.clnesp.2022.02.010","article-title":"The effects of selenium plus probiotics supplementation on glycemic status and serum lipoproteins in patients with gestational diabetes mellitus: a randomized, double-blind, placebo-controlled trial","volume":"48","author":"Amirani","year":"2022","journal-title":"Clin Nutr ESPEN"},{"key":"10.1016\/j.xagr.2023.100285_bib0029","doi-asserted-by":"crossref","first-page":"461","DOI":"10.3390\/nu9050461","article-title":"Effect of probiotics on metabolic outcomes in pregnant women with gestational diabetes: a systematic review and meta-analysis of randomized controlled trials","volume":"9","author":"Taylor","year":"2017","journal-title":"Nutrients"},{"key":"10.1016\/j.xagr.2023.100285_bib0030","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1080\/14767058.2017.1376318","article-title":"Efficacy of probiotic supplement for gestational diabetes mellitus: a systematic review and meta-analysis","volume":"32","author":"Pan","year":"2019","journal-title":"J Matern Fetal Neonatal Med"},{"key":"10.1016\/j.xagr.2023.100285_bib0031","doi-asserted-by":"crossref","first-page":"17796","DOI":"10.1038\/s41598-020-74773-8","article-title":"Improvement of glucose metabolism in pregnant women through probiotic supplementation depends on gestational diabetes status: meta-analysis","volume":"10","author":"\u0141agowska","year":"2020","journal-title":"Sci Rep"},{"key":"10.1016\/j.xagr.2023.100285_bib0032","doi-asserted-by":"crossref","DOI":"10.1155\/2021\/9830200","article-title":"Probiotic supplements improve blood glucose and insulin resistance\/sensitivity among healthy and GDM pregnant women: a systematic review and meta-analysis of randomized controlled trials","volume":"2021","author":"Pan","year":"2021","journal-title":"Evid Based Complement Alternat Med"},{"key":"10.1016\/j.xagr.2023.100285_bib0033","doi-asserted-by":"crossref","first-page":"12216","DOI":"10.1038\/s41598-018-30735-9","article-title":"Changes in the gut microbiota composition during pregnancy in patients with gestational diabetes mellitus (GDM)","volume":"8","author":"Ferrocino","year":"2018","journal-title":"Sci Rep"},{"key":"10.1016\/j.xagr.2023.100285_bib0034","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1186\/s40168-018-0472-x","article-title":"Gestational diabetes is associated with change in the gut microbiota composition in third trimester of pregnancy and postpartum","volume":"6","author":"Crusell","year":"2018","journal-title":"Microbiome"},{"key":"10.1016\/j.xagr.2023.100285_bib0035","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1093\/gigascience\/gix058","article-title":"Connections between the human gut microbiome and gestational diabetes mellitus","volume":"6","author":"Kuang","year":"2017","journal-title":"Gigascience"},{"key":"10.1016\/j.xagr.2023.100285_bib0036","doi-asserted-by":"crossref","first-page":"1792","DOI":"10.1017\/S0007114509993898","article-title":"Impact of maternal probiotic-supplemented dietary counselling on pregnancy outcome and prenatal and postnatal growth: a double-blind, placebo-controlled study","volume":"103","author":"Luoto","year":"2010","journal-title":"Br J Nutr"},{"key":"10.1016\/j.xagr.2023.100285_bib0037","doi-asserted-by":"crossref","DOI":"10.1155\/2019\/5364730","article-title":"Effects of probiotic supplement in pregnant women with gestational diabetes mellitus: a systematic review and meta-analysis of randomized controlled trials","volume":"2019","author":"Zhang","year":"2019","journal-title":"J Diabetes Res"},{"key":"10.1016\/j.xagr.2023.100285_bib0038","doi-asserted-by":"crossref","first-page":"937","DOI":"10.1016\/j.pcd.2021.08.005","article-title":"Probiotics and Synbiotics show clinical efficacy in treating gestational diabetes mellitus: a meta-analysis","volume":"15","author":"Zhou","year":"2021","journal-title":"Prim Care Diabetes"},{"key":"10.1016\/j.xagr.2023.100285_bib0039","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1515\/hmbci-2015-0025","article-title":"Maternal and fetal lipid metabolism under normal and gestational diabetic conditions","volume":"26","author":"Herrera","year":"2016","journal-title":"Horm Mol Biol Clin Investig"},{"key":"10.1016\/j.xagr.2023.100285_bib0040","doi-asserted-by":"crossref","first-page":"1163","DOI":"10.1194\/jlr.R100020-JLR200","article-title":"Hepatic lipase: structure\/function relationship, synthesis, and regulation","volume":"43","author":"Perret","year":"2002","journal-title":"J Lipid Res"},{"key":"10.1016\/j.xagr.2023.100285_bib0041","doi-asserted-by":"crossref","first-page":"70","DOI":"10.1515\/med-2021-0408","article-title":"Effect of gestational diabetes mellitus on lipid profile: a systematic review and meta-analysis","volume":"17","author":"Rahnemaei","year":"2022","journal-title":"Open Med (Wars)"},{"key":"10.1016\/j.xagr.2023.100285_bib0042","doi-asserted-by":"crossref","first-page":"188","DOI":"10.3389\/fcimb.2020.00188","article-title":"Gut microbiota and gestational diabetes mellitus: a review of host-gut microbiota interactions and their therapeutic potential","volume":"10","author":"Hasain","year":"2020","journal-title":"Front Cell Infect Microbiol"},{"key":"10.1016\/j.xagr.2023.100285_bib0043","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1016\/j.jnutbio.2017.08.006","article-title":"Probiotics modulate gut microbiota and improve insulin sensitivity in DIO mice","volume":"50","author":"Bagarolli","year":"2017","journal-title":"J Nutr Biochem"}],"container-title":["AJOG Global Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2666577823001272?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2666577823001272?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,13]],"date-time":"2025-11-13T02:22:14Z","timestamp":1763000534000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2666577823001272"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,2]]},"references-count":43,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2024,2]]}},"alternative-id":["S2666577823001272"],"URL":"https:\/\/doi.org\/10.1016\/j.xagr.2023.100285","relation":{},"ISSN":["2666-5778"],"issn-type":[{"value":"2666-5778","type":"print"}],"subject":[],"published":{"date-parts":[[2024,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"The role of probiotics and synbiotics on treatment of gestational diabetes: systematic review and meta-analysis","name":"articletitle","label":"Article Title"},{"value":"AJOG Global Reports","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.xagr.2023.100285","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2023 The Authors. Published by Elsevier Inc.","name":"copyright","label":"Copyright"}],"article-number":"100285"}}