{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,27]],"date-time":"2026-10-27T00:35:18Z","timestamp":1793061318199,"version":"4.5.0"},"reference-count":51,"publisher":"Elsevier BV","issue":"8","license":[{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,7,2]],"date-time":"2026-07-02T00:00:00Z","timestamp":1782950400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100010296","name":"James B. Pendleton Charitable Trust","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100010296","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["cell.com","clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Cell Reports Medicine"],"published-print":{"date-parts":[[2026,8]]},"DOI":"10.1016\/j.xcrm.2026.102946","type":"journal-article","created":{"date-parts":[[2026,7,29]],"date-time":"2026-07-29T14:40:35Z","timestamp":1785336035000},"page":"102946","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":2,"title":["Persistent cytolytic CD8+ T cells recognize SARS-CoV-2 and herpesvirus epitopes in long COVID"],"prefix":"10.1016","volume":"7","author":[{"given":"Tongcui","family":"Ma","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Heeju","family":"Ryu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kailin","family":"Yin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas","family":"Dalhuisen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Douglas","family":"Robbins","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tyrine T.","family":"Bailey","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sean A.","family":"Thomas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emily A.","family":"Fehrman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J. Daniel","family":"Kelly","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeffrey N.","family":"Martin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kara L.","family":"Lynch","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sulggi A.","family":"Lee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Steven G.","family":"Deeks","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Timothy J.","family":"Henrich","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael J.","family":"Peluso","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Evan W.","family":"Newell","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5464-1976","authenticated-orcid":false,"given":"Nadia R.","family":"Roan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.xcrm.2026.102946_bib1","doi-asserted-by":"crossref","first-page":"1746","DOI":"10.1056\/NEJMsb2408466","article-title":"National Academies of Sciences E and Medicine Committee on Examining the Working Definition for Long Covid Defined","volume":"391","author":"Ely","year":"2024","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.xcrm.2026.102946_bib2","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1038\/s41579-022-00846-2","article-title":"Long COVID: major findings, mechanisms and recommendations","volume":"21","author":"Davis","year":"2023","journal-title":"Nat. Rev. Microbiol."},{"key":"10.1016\/j.xcrm.2026.102946_bib3","doi-asserted-by":"crossref","first-page":"5500","DOI":"10.1016\/j.cell.2024.07.054","article-title":"Mechanisms of long COVID and the path toward therapeutics","volume":"187","author":"Peluso","year":"2024","journal-title":"Cell"},{"key":"10.1016\/j.xcrm.2026.102946_bib4","doi-asserted-by":"crossref","first-page":"101873","DOI":"10.1016\/j.smim.2024.101873","article-title":"Systems analysis of innate and adaptive immunity in Long COVID","volume":"72","author":"Peluso","year":"2024","journal-title":"Semin. Immunol."},{"key":"10.1016\/j.xcrm.2026.102946_bib5","doi-asserted-by":"crossref","first-page":"881","DOI":"10.1016\/j.cell.2022.01.014","article-title":"Multiple early factors anticipate post-acute COVID-19 sequelae","volume":"185","author":"Su","year":"2022","journal-title":"Cell"},{"key":"10.1016\/j.xcrm.2026.102946_bib6","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1038\/s41586-023-06651-y","article-title":"Distinguishing features of long COVID identified through immune profiling","volume":"623","author":"Klein","year":"2023","journal-title":"Nature"},{"key":"10.1016\/j.xcrm.2026.102946_bib7","doi-asserted-by":"crossref","first-page":"e163669","DOI":"10.1172\/JCI163669","article-title":"Chronic viral coinfections differentially affect the likelihood of developing long COVID","volume":"133","author":"Peluso","year":"2023","journal-title":"J. Clin. Investig."},{"key":"10.1016\/j.xcrm.2026.102946_bib8","doi-asserted-by":"crossref","DOI":"10.1126\/science.adg7942","article-title":"Persistent complement dysregulation with signs of thromboinflammation in active Long Covid","volume":"383","author":"Cervia-Hasler","year":"2024","journal-title":"Science"},{"key":"10.1016\/j.xcrm.2026.102946_bib9","doi-asserted-by":"crossref","DOI":"10.1126\/scitranslmed.adk3295","article-title":"Tissue-based T cell activation and viral RNA persist for up to 2 years after SARS-CoV-2 infection","volume":"16","author":"Peluso","year":"2024","journal-title":"Sci. Transl. Med."},{"key":"10.1016\/j.xcrm.2026.102946_bib10","doi-asserted-by":"crossref","first-page":"e294","DOI":"10.1016\/S1473-3099(24)00769-2","article-title":"Targeting the SARS-CoV-2 reservoir in long COVID","volume":"25","author":"Proal","year":"2025","journal-title":"Lancet Infect. Dis."},{"key":"10.1016\/j.xcrm.2026.102946_bib11","doi-asserted-by":"crossref","first-page":"1772","DOI":"10.1038\/s41467-023-37368-1","article-title":"Post-acute sequelae of COVID-19 is characterized by diminished peripheral CD8(+)beta7 integrin(+) T cells and anti-SARS-CoV-2 IgA response","volume":"14","author":"Santa Cruz","year":"2023","journal-title":"Nat. Commun."},{"key":"10.1016\/j.xcrm.2026.102946_bib12","first-page":"720","article-title":"Alterations in T and B cell function persist in convalescent COVID-19 patients","volume":"2","author":"Shuwa","year":"2021","journal-title":"M\u00e9d. Sur"},{"key":"10.1016\/j.xcrm.2026.102946_bib13","doi-asserted-by":"crossref","first-page":"218","DOI":"10.1038\/s41590-023-01724-6","article-title":"Long COVID manifests with T cell dysregulation, inflammation and an uncoordinated adaptive immune response to SARS-CoV-2","volume":"25","author":"Yin","year":"2024","journal-title":"Nat. Immunol."},{"key":"10.1016\/j.xcrm.2026.102946_bib14","doi-asserted-by":"crossref","first-page":"442","DOI":"10.1038\/s41577-020-0348-8","article-title":"Considering how biological sex impacts immune responses and COVID-19 outcomes","volume":"20","author":"Scully","year":"2020","journal-title":"Nat. Rev. Immunol."},{"key":"10.1016\/j.xcrm.2026.102946_bib15","doi-asserted-by":"crossref","DOI":"10.1073\/pnas.2411428121","article-title":"SARS-CoV-2-specific CD8(+) T cells from people with long COVID establish and maintain effector phenotype and key TCR signatures over 2 years","volume":"121","author":"Rowntree","year":"2024","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.xcrm.2026.102946_bib16","doi-asserted-by":"crossref","first-page":"623","DOI":"10.1038\/nbt.2593","article-title":"Combinatorial tetramer staining and mass cytometry analysis facilitate T-cell epitope mapping and characterization","volume":"31","author":"Newell","year":"2013","journal-title":"Nat. Biotechnol."},{"key":"10.1016\/j.xcrm.2026.102946_bib17","doi-asserted-by":"crossref","DOI":"10.1093\/ofid\/ofab640","article-title":"Persistence, Magnitude, and Patterns of Postacute Symptoms and Quality of Life Following Onset of SARS-CoV-2 Infection: Cohort Description and Approaches for Measurement","volume":"9","author":"Peluso","year":"2022","journal-title":"Open Forum Infect. Dis."},{"key":"10.1016\/j.xcrm.2026.102946_bib18","doi-asserted-by":"crossref","first-page":"eabf7550","DOI":"10.1126\/sciimmunol.abf7550","article-title":"SARS-CoV-2 genome-wide T cell epitope mapping reveals immunodominance and substantial CD8(+) T cell activation in COVID-19 patients","volume":"6","author":"Saini","year":"2021","journal-title":"Sci. Immunol."},{"key":"10.1016\/j.xcrm.2026.102946_bib19","doi-asserted-by":"crossref","first-page":"1489","DOI":"10.1016\/j.cell.2020.05.015","article-title":"Targets of T Cell Responses to SARS-CoV-2 Coronavirus in Humans with COVID-19 Disease and Unexposed Individuals","volume":"181","author":"Grifoni","year":"2020","journal-title":"Cell."},{"key":"10.1016\/j.xcrm.2026.102946_bib20","doi-asserted-by":"crossref","first-page":"100204","DOI":"10.1016\/j.xcrm.2021.100204","article-title":"Comprehensive analysis of T cell immunodominance and immunoprevalence of SARS-CoV-2 epitopes in COVID-19 cases","volume":"2","author":"Tarke","year":"2021","journal-title":"Cell Rep. Med."},{"key":"10.1016\/j.xcrm.2026.102946_bib21","doi-asserted-by":"crossref","first-page":"101149","DOI":"10.1016\/j.xcrm.2023.101149","article-title":"mRNA vaccination boosts S-specific T cell memory and promotes expansion of CD45RA(int) T(EMRA)-like CD8(+) T cells in COVID-19 recovered individuals","volume":"4","author":"Mayer-Blackwell","year":"2023","journal-title":"Cell Rep. Med."},{"key":"10.1016\/j.xcrm.2026.102946_bib22","doi-asserted-by":"crossref","first-page":"575","DOI":"10.1038\/s41586-018-0130-2","article-title":"Bystander CD8(+) T cells are abundant and phenotypically distinct in human tumour infiltrates","volume":"557","author":"Simoni","year":"2018","journal-title":"Nature"},{"key":"10.1016\/j.xcrm.2026.102946_bib23","doi-asserted-by":"crossref","first-page":"101390","DOI":"10.1016\/j.xcrm.2023.101390","article-title":"Merkel cell polyomavirus-specific and CD39(+)CLA(+) CD8 T cells as blood-based predictive biomarkers for PD-1 blockade in Merkel cell carcinoma","volume":"5","author":"Ryu","year":"2024","journal-title":"Cell Rep. Med."},{"key":"10.1016\/j.xcrm.2026.102946_bib24","doi-asserted-by":"crossref","first-page":"1415914","DOI":"10.3389\/fimmu.2024.1415914","article-title":"The role of circulating T cells with a tissue resident phenotype (ex-T(RM)) in health and disease","volume":"15","author":"Rodger","year":"2024","journal-title":"Front. Immunol."},{"key":"10.1016\/j.xcrm.2026.102946_bib25","doi-asserted-by":"crossref","first-page":"eaav8995","DOI":"10.1126\/sciimmunol.aav8995","article-title":"Human CD4(+)CD103(+) cutaneous resident memory T cells are found in the circulation of healthy individuals","volume":"4","author":"Klicznik","year":"2019","journal-title":"Sci. Immunol."},{"key":"10.1016\/j.xcrm.2026.102946_bib26","doi-asserted-by":"crossref","first-page":"6686","DOI":"10.1073\/pnas.1913940117","article-title":"CD29 identifies IFN-gamma-producing human CD8(+) T cells with an increased cytotoxic potential","volume":"117","author":"Nicolet","year":"2020","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.xcrm.2026.102946_bib27","doi-asserted-by":"crossref","first-page":"3583","DOI":"10.4049\/jimmunol.1001535","article-title":"IL-10 restricts memory T cell inflation during cytomegalovirus infection","volume":"185","author":"Jones","year":"2010","journal-title":"J. Immunol."},{"key":"10.1016\/j.xcrm.2026.102946_bib28","doi-asserted-by":"crossref","first-page":"eadk3295","DOI":"10.1126\/scitranslmed.adk3295","article-title":"Tissue-Based T Cell Activation and Viral RNA Persist for Up to 2 Years After SARS-CoV-2 Infection","volume":"3","author":"Peluso","year":"2024","journal-title":"Sci Transl Med"},{"key":"10.1016\/j.xcrm.2026.102946_bib29","doi-asserted-by":"crossref","first-page":"684","DOI":"10.1038\/s41590-020-0643-3","article-title":"Sestrins induce natural killer function in senescent-like CD8(+) T cells","volume":"21","author":"Pereira","year":"2020","journal-title":"Nat. Immunol."},{"key":"10.1016\/j.xcrm.2026.102946_bib30","doi-asserted-by":"crossref","first-page":"1098200","DOI":"10.3389\/fragi.2022.1098200","article-title":"NK- and T-cell granzyme B and K expression correlates with age, CMV infection and influenza vaccine-induced antibody titres in older adults","volume":"3","author":"Verschoor","year":"2023","journal-title":"Front. Aging"},{"key":"10.1016\/j.xcrm.2026.102946_bib31","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1016\/j.aller.2011.01.002","article-title":"Aging and asthma - changes in CD45RA, CD29 and CD95 T cells subsets","volume":"40","author":"Todo-Bom","year":"2012","journal-title":"Allergol. Immunopathol."},{"key":"10.1016\/j.xcrm.2026.102946_bib32","doi-asserted-by":"crossref","first-page":"e136648","DOI":"10.1172\/jci.insight.136648","article-title":"TCF-1 regulates HIV-specific CD8+ T cell expansion capacity","volume":"6","author":"Rutishauser","year":"2021","journal-title":"JCI Insight"},{"key":"10.1016\/j.xcrm.2026.102946_bib33","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1038\/s41586-025-09929-5","article-title":"Correlates of HIV-1 control after combination immunotherapy","volume":"650","author":"Peluso","year":"2026","journal-title":"Nature"},{"key":"10.1016\/j.xcrm.2026.102946_bib34","doi-asserted-by":"crossref","first-page":"196","DOI":"10.1038\/s41586-025-09932-w","article-title":"CD8(+) T cell stemness precedes post-intervention control of HIV viraemia","volume":"650","author":"Kiani","year":"2026","journal-title":"Nature"},{"key":"10.1016\/j.xcrm.2026.102946_bib35","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1038\/nri2056","article-title":"Siglecs and their roles in the immune system","volume":"7","author":"Crocker","year":"2007","journal-title":"Nat. Rev. Immunol."},{"key":"10.1016\/j.xcrm.2026.102946_bib36","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1038\/s41467-025-66540-y","article-title":"HIV-induced sialoglycans on infected CD4+ T cells promote immune evasion from myeloid cell-mediated killing","volume":"17","author":"Singh","year":"2025","journal-title":"Nat. Commun."},{"key":"10.1016\/j.xcrm.2026.102946_bib37","doi-asserted-by":"crossref","first-page":"1178","DOI":"10.3390\/biology10111178","article-title":"Siglecs as Therapeutic Targets in Cancer","volume":"10","author":"Lim","year":"2021","journal-title":"Biology"},{"key":"10.1016\/j.xcrm.2026.102946_bib38","doi-asserted-by":"crossref","first-page":"427","DOI":"10.1038\/s41417-023-00713-z","article-title":"Siglec-15 on macrophages suppress the immune microenvironment in patients with PD-L1 negative non-metastasis lung adenocarcinoma","volume":"31","author":"Huang","year":"2024","journal-title":"Cancer Gene Ther."},{"key":"10.1016\/j.xcrm.2026.102946_bib39","doi-asserted-by":"crossref","first-page":"656","DOI":"10.1038\/s41591-019-0374-x","article-title":"Siglec-15 as an immune suppressor and potential target for normalization cancer immunotherapy","volume":"25","author":"Wang","year":"2019","journal-title":"Nat. Med."},{"key":"10.1016\/j.xcrm.2026.102946_bib40","doi-asserted-by":"crossref","first-page":"680","DOI":"10.1158\/1078-0432.CCR-19-2925","article-title":"Siglec-15 as an Emerging Target for Next-generation Cancer Immunotherapy","volume":"27","author":"Sun","year":"2021","journal-title":"Clin. Cancer Res."},{"key":"10.1016\/j.xcrm.2026.102946_bib41","doi-asserted-by":"crossref","first-page":"509","DOI":"10.1038\/gene.2009.12","article-title":"Stronger inflammatory\/cytotoxic T-cell response in women identified by microarray analysis","volume":"10","author":"Hewagama","year":"2009","journal-title":"Gene Immun."},{"key":"10.1016\/j.xcrm.2026.102946_bib42","doi-asserted-by":"crossref","first-page":"599","DOI":"10.1126\/science.adx4381","article-title":"Sex differences in tissue-specific immunity and immunology","volume":"389","author":"Sharma","year":"2025","journal-title":"Science"},{"key":"10.1016\/j.xcrm.2026.102946_bib43","doi-asserted-by":"crossref","first-page":"306","DOI":"10.1136\/bmj.1.5953.306","article-title":"Normal haematological values: sex difference in neutrophil count","volume":"1","author":"Bain","year":"1975","journal-title":"Br. Med. J."},{"key":"10.1016\/j.xcrm.2026.102946_bib44","doi-asserted-by":"crossref","first-page":"108485","DOI":"10.1016\/j.celrep.2020.108485","article-title":"Heterogeneous Escape from X Chromosome Inactivation Results in Sex Differences in Type I IFN Responses at the Single Human pDC Level","volume":"33","author":"Hagen","year":"2020","journal-title":"Cell Rep."},{"key":"10.1016\/j.xcrm.2026.102946_bib45","doi-asserted-by":"crossref","first-page":"1084","DOI":"10.1093\/infdis\/jiy617","article-title":"Sex-Based Differences in HIV-1 Reservoir Activity and Residual Immune Activation","volume":"219","author":"Scully","year":"2018","journal-title":"J Infect Dis"},{"key":"10.1016\/j.xcrm.2026.102946_bib46","doi-asserted-by":"crossref","first-page":"485","DOI":"10.2340\/00015555-2306","article-title":"Up-regulation of Proinflammatory Genes and Cytokines Induced by S100A8 in CD8+ T Cells in Lichen Planus","volume":"96","author":"Carvalho","year":"2016","journal-title":"Acta Derm. Venerol."},{"key":"10.1016\/j.xcrm.2026.102946_bib47","first-page":"26, 327","article-title":"Abortive infection: T cells as early, antibody-independent defenders","author":"Swadling","year":"2026","journal-title":"Nat. Rev. Immunol."},{"key":"10.1016\/j.xcrm.2026.102946_bib48","doi-asserted-by":"crossref","first-page":"109414","DOI":"10.1016\/j.celrep.2021.109414","article-title":"Distinctive features of SARS-CoV-2-specific T cells predict recovery from severe COVID-19","volume":"36","author":"Neidleman","year":"2021","journal-title":"Cell Rep."},{"key":"10.1016\/j.xcrm.2026.102946_bib49","doi-asserted-by":"crossref","DOI":"10.1126\/scitranslmed.ado2104","article-title":"Animal models of Long Covid: A hit-and-run disease","volume":"16","author":"Schafer","year":"2024","journal-title":"Sci. Transl. Med."},{"key":"10.1016\/j.xcrm.2026.102946_bib50","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1007\/978-1-4939-9454-0_11","article-title":"Multiplex MHC Class I Tetramer Combined with Intranuclear Staining by Mass Cytometry","volume":"1989","author":"Simoni","year":"2019","journal-title":"Methods Mol. Biol."},{"key":"10.1016\/j.xcrm.2026.102946_bib51","doi-asserted-by":"crossref","first-page":"148","DOI":"10.1016\/j.immuni.2016.11.005","article-title":"Human Innate Lymphoid Cell Subsets Possess Tissue-Type Based Heterogeneity in Phenotype and Frequency","volume":"46","author":"Simoni","year":"2017","journal-title":"Immunity"}],"container-title":["Cell Reports Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2666379126003630?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2666379126003630?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,10,27]],"date-time":"2026-10-27T00:21:57Z","timestamp":1793060517000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2666379126003630"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,8]]},"references-count":51,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2026,8]]}},"alternative-id":["S2666379126003630"],"URL":"https:\/\/doi.org\/10.1016\/j.xcrm.2026.102946","relation":{},"ISSN":["2666-3791"],"issn-type":[{"value":"2666-3791","type":"print"}],"subject":[],"published":{"date-parts":[[2026,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Persistent cytolytic CD8+ T cells recognize SARS-CoV-2 and herpesvirus epitopes in long COVID","name":"articletitle","label":"Article Title"},{"value":"Cell Reports Medicine","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.xcrm.2026.102946","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 The Author(s). Published by Elsevier Inc.","name":"copyright","label":"Copyright"}],"article-number":"102946"}}