{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T19:21:46Z","timestamp":1791400906072,"version":"4.3.3"},"reference-count":22,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2022,12,1]],"date-time":"2022-12-01T00:00:00Z","timestamp":1669852800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,12,1]],"date-time":"2022-12-01T00:00:00Z","timestamp":1669852800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2022,10,19]],"date-time":"2022-10-19T00:00:00Z","timestamp":1666137600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["fertstertreports.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["F&S Reports"],"published-print":{"date-parts":[[2022,12]]},"DOI":"10.1016\/j.xfre.2022.10.002","type":"journal-article","created":{"date-parts":[[2022,10,20]],"date-time":"2022-10-20T04:02:30Z","timestamp":1666238550000},"page":"342-348","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":5,"title":["Patients with Recurrent Pregnancy Loss Have Similar Embryonic Preimplantation Genetic Testing Aneuploidy Rates and In\u00a0Vitro Fertilization Outcomes to Infertility Patients"],"prefix":"10.1016","volume":"3","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5005-1840","authenticated-orcid":false,"given":"Molly Siegel","family":"Kornfield","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2412-3614","authenticated-orcid":false,"given":"Pamela","family":"Parker","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7567-0151","authenticated-orcid":false,"given":"Elizabeth","family":"Rubin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6731-0623","authenticated-orcid":false,"given":"Bharti","family":"Garg","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas","family":"O\u2019Leary","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paula","family":"Amato","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Lee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Diana","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sacha","family":"Krieg","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.xfre.2022.10.002_bib1","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1136\/jech.38.1.29","article-title":"Fetal loss rates and their relation to pregnancy order","volume":"38","author":"Roman","year":"1984","journal-title":"J Epidemiol Community Health"},{"key":"10.1016\/j.xfre.2022.10.002_bib2","doi-asserted-by":"crossref","first-page":"777","DOI":"10.1093\/humrep\/dev014","article-title":"Depression and emotional stress are highly prevalent among women with recurrent pregnancy loss","volume":"30","author":"Kolte","year":"2015","journal-title":"Hum Reprod"},{"key":"10.1016\/j.xfre.2022.10.002_bib3","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1080\/14647273.2018.1475754","article-title":"Ongoing pregnancies in patients with unexplained recurrent pregnancy loss: adverse obstetric outcomes","volume":"22","author":"Cozzolino","year":"2019","journal-title":"Hum Fertil (Camb)"},{"key":"10.1016\/j.xfre.2022.10.002_bib4","doi-asserted-by":"crossref","first-page":"389","DOI":"10.1515\/jpm-2011-0315","article-title":"Primary vs. secondary recurrent pregnancy loss\u2014epidemiological characteristics, etiology, and next pregnancy outcome","volume":"40","author":"Shapira","year":"2012","journal-title":"J Perinat Med"},{"key":"10.1016\/j.xfre.2022.10.002_bib5","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1016\/S0015-0282(16)58382-4","article-title":"Frequency of factors associated with habitual abortion in 197 couples","volume":"66","author":"Stephenson","year":"1996","journal-title":"Fertil Steril"},{"key":"10.1016\/j.xfre.2022.10.002_bib6","first-page":"197","article-title":"200. Early Pregnancy Loss. American College of Obstetricians and Gynecologists","volume":"132","year":"2018","journal-title":"Obstet Gynecol"},{"key":"10.1016\/j.xfre.2022.10.002_bib7","doi-asserted-by":"crossref","first-page":"300","DOI":"10.1016\/S0015-0282(99)00495-1","article-title":"Embryonic karyotype of abortuses in relation to the number of previous miscarriages","volume":"73","author":"Ogasawara","year":"2000","journal-title":"Fertil Steril Elsevier"},{"key":"10.1016\/j.xfre.2022.10.002_bib8","doi-asserted-by":"crossref","first-page":"446","DOI":"10.1093\/humrep\/17.2.446","article-title":"Cytogenetic analysis of miscarriages from couples with recurrent miscarriage: a case-control study","volume":"17","author":"Stephenson","year":"2002","journal-title":"Hum Reprod"},{"key":"10.1016\/j.xfre.2022.10.002_bib9","doi-asserted-by":"crossref","first-page":"1028","DOI":"10.1016\/j.fertnstert.2017.01.022","article-title":"Comparison of cytogenetics and molecular karyotyping for chromosome testing of miscarriage specimens","volume":"107","author":"Shah","year":"2017","journal-title":"Fertil Steril"},{"key":"10.1016\/j.xfre.2022.10.002_bib10","doi-asserted-by":"crossref","first-page":"331","DOI":"10.1016\/j.fertnstert.2005.02.027","article-title":"Preimplantation genetic diagnosis reduces pregnancy loss in women aged 35 years and older with a history of recurrent miscarriages","volume":"84","author":"Munn\u00e9","year":"2005","journal-title":"Fertil Steril"},{"key":"10.1016\/j.xfre.2022.10.002_bib11","doi-asserted-by":"crossref","first-page":"288","DOI":"10.1016\/j.fertnstert.2008.05.056","article-title":"Effect of infertility, maternal age, and number of previous miscarriages on the outcome of preimplantation genetic diagnosis for idiopathic recurrent pregnancy loss","volume":"92","author":"Garrisi","year":"2009","journal-title":"Fertil Steril"},{"key":"10.1016\/j.xfre.2022.10.002_bib12","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1111\/j.1600-0897.2005.00260.x","article-title":"Embryo aneuploidy screening for unexplained recurrent miscarriage: a minireview","volume":"53","author":"Rubio","year":"2005","journal-title":"Am J Reprod Immunol"},{"key":"10.1016\/j.xfre.2022.10.002_bib13","doi-asserted-by":"crossref","first-page":"1124","DOI":"10.1016\/j.fertnstert.2016.06.016","article-title":"Higher rates of aneuploidy in blastocysts and higher risk of no embryo transfer in recurrent pregnancy loss patients with diminished ovarian reserve undergoing in\u00a0vitro fertilization","volume":"106","author":"Shahine","year":"2016","journal-title":"Fertil Steril"},{"key":"10.1016\/j.xfre.2022.10.002_bib14","doi-asserted-by":"crossref","first-page":"403","DOI":"10.1007\/s10815-017-1060-x","article-title":"Are blastocyst aneuploidy rates different between fertile and infertile populations?","volume":"35","author":"Kort","year":"2018","journal-title":"J Assist Reprod Genet"},{"key":"10.1016\/j.xfre.2022.10.002_bib15","article-title":"ESHRE guideline: recurrent pregnancy loss","author":"Bender","year":"2018","journal-title":"Hum Reprod Open"},{"issue":"Suppl B","key":"10.1016\/j.xfre.2022.10.002_bib16","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1016\/S0143-4004(03)00136-X","article-title":"Assessment of embryo viability: the ability to select a single embryo for transfer-a review","volume":"24","author":"Gardner","year":"2003","journal-title":"Placenta"},{"key":"10.1016\/j.xfre.2022.10.002_bib17","doi-asserted-by":"crossref","first-page":"2868","DOI":"10.1093\/humrep\/14.11.2868","article-title":"A longitudinal study of pregnancy outcome following idiopathic recurrent miscarriage","volume":"14","author":"Brigham","year":"1999","journal-title":"Hum Reprod"},{"key":"10.1016\/j.xfre.2022.10.002_bib18","doi-asserted-by":"crossref","first-page":"258","DOI":"10.1111\/jog.13837","article-title":"New insights into the mechanisms underlying recurrent pregnancy loss","volume":"45","author":"Ewington","year":"2019","journal-title":"J Obstet Gynaecol Res"},{"key":"10.1016\/j.xfre.2022.10.002_bib19","doi-asserted-by":"crossref","first-page":"1103","DOI":"10.1016\/j.fertnstert.2012.06.048","article-title":"Evaluation and treatment of recurrent pregnancy loss: a committee opinion","volume":"98","year":"2012","journal-title":"Fertil Steril"},{"key":"10.1016\/j.xfre.2022.10.002_bib20","doi-asserted-by":"crossref","first-page":"1668","DOI":"10.1093\/humrep\/dew135","article-title":"Intent to treat analysis of in\u00a0vitro fertilization and preimplantation genetic screening versus expectant management in patients with recurrent pregnancy loss","volume":"31","author":"Murugappan","year":"2016","journal-title":"Hum Reprod"},{"key":"10.1016\/j.xfre.2022.10.002_bib21","doi-asserted-by":"crossref","first-page":"1215","DOI":"10.1016\/j.fertnstert.2015.02.012","article-title":"Cost-effectiveness analysis of preimplantation genetic screening and in\u00a0vitro fertilization versus expectant management in patients with unexplained recurrent pregnancy loss","volume":"103","author":"Murugappan","year":"2015","journal-title":"Fertil Steril"},{"key":"10.1016\/j.xfre.2022.10.002_bib22","doi-asserted-by":"crossref","first-page":"2340","DOI":"10.1093\/humrep\/dez229","article-title":"Preimplantation genetic testing for aneuploidy: a comparison of live birth rates in patients with recurrent pregnancy loss due to embryonic aneuploidy or recurrent implantation failure","volume":"34","author":"Sato","year":"2019","journal-title":"Hum Reprod"}],"container-title":["F&S Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2666334122001088?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2666334122001088?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,12]],"date-time":"2025-11-12T21:05:45Z","timestamp":1762981545000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2666334122001088"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,12]]},"references-count":22,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2022,12]]}},"alternative-id":["S2666334122001088"],"URL":"https:\/\/doi.org\/10.1016\/j.xfre.2022.10.002","relation":{},"ISSN":["2666-3341"],"issn-type":[{"value":"2666-3341","type":"print"}],"subject":[],"published":{"date-parts":[[2022,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Patients with Recurrent Pregnancy Loss Have Similar Embryonic Preimplantation Genetic Testing Aneuploidy Rates and In\u00a0Vitro Fertilization Outcomes to Infertility Patients","name":"articletitle","label":"Article Title"},{"value":"F&S Reports","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.xfre.2022.10.002","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2022 The Author(s). Published by Elsevier Inc. on behalf of American Society for Reproductive Medicine.","name":"copyright","label":"Copyright"}]}}