{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,12]],"date-time":"2025-11-12T22:10:00Z","timestamp":1762985400724,"version":"3.45.0"},"reference-count":18,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2023,6,1]],"date-time":"2023-06-01T00:00:00Z","timestamp":1685577600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,6,1]],"date-time":"2023-06-01T00:00:00Z","timestamp":1685577600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2023,2,27]],"date-time":"2023-02-27T00:00:00Z","timestamp":1677456000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["fertstertreports.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["F&amp;S Reports"],"published-print":{"date-parts":[[2023,6]]},"DOI":"10.1016\/j.xfre.2023.02.012","type":"journal-article","created":{"date-parts":[[2023,3,1]],"date-time":"2023-03-01T18:19:03Z","timestamp":1677694743000},"page":"144-149","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":2,"title":["Pregnancy outcomes in in vitro fertilization in 17-alpha-hydroxylase deficiency"],"prefix":"10.1016","volume":"4","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5484-2591","authenticated-orcid":false,"given":"Annika","family":"van Oosbree","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ayesha","family":"Asif","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9820-1593","authenticated-orcid":false,"given":"Sarah","family":"Hmaidan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alan","family":"DeCherney","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.xfre.2023.02.012_bib1","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1016\/j.fertnstert.2013.11.011","article-title":"Fertility in patients with genetic deficiencies of cytochrome P450c17 (CYP17A1): combined 17-hydoxylase\/17,20-lyase deficiency","volume":"101","author":"Marsh","year":"2014","journal-title":"Fertil Steril"},{"key":"10.1016\/j.xfre.2023.02.012_bib2","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1016\/S0889-8529(08)70021-5","article-title":"The genetics, pathophysiology, and management of human deficiencies of P450c17","volume":"30","author":"Auchus","year":"2001","journal-title":"Endocrilol Metab Clin North Am"},{"key":"10.1016\/j.xfre.2023.02.012_bib3","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1016\/S0015-0282(16)49955-3","article-title":"Arrest of follicular development in a patient with 17-alpha-hydroxylase deficiency: follibulogenesis in association with a lack of estrogen synthesis in the ovaries","volume":"41","author":"Arai","year":"1987","journal-title":"Fertil Steril"},{"key":"10.1016\/j.xfre.2023.02.012_bib4","first-page":"3797","article-title":"Mutation of cytochrome P-45017 alpha gene (CYP17) in a Japanse patient previously reported as having lugocorticoid-responsive hyperaldosteronism: with a review of Japanese patients with mutaitons of CYP17","volume":"81","author":"Miura","year":"1996","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1016\/j.xfre.2023.02.012_bib5","doi-asserted-by":"crossref","first-page":"2456","DOI":"10.1093\/oxfordjournals.humrep.a136319","article-title":"Induction of artificial endometrial cycles with oestradiol implants and injectable progesterone: establishment of a viable pregnancy in a woman with 17-alpha-hydroxylase deficiency","volume":"10","author":"Ben-Nun","year":"1995","journal-title":"Hum Reprod"},{"key":"10.1016\/j.xfre.2023.02.012_bib6","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1023\/A:1021206704958","article-title":"Familial partial 17,20-desmolase and 17alpha-hydroxylase deficiency presenting as infertility","volume":"20","author":"Levran","year":"2003","journal-title":"J Assist Reprod Genet"},{"key":"10.1016\/j.xfre.2023.02.012_bib7","doi-asserted-by":"crossref","first-page":"345","DOI":"10.1210\/jc.2015-3201","article-title":"Successful live birth in a woman with 17-alpha-hydroxylase deficiency through IVF frozen-thawed embryo transfer","volume":"101","author":"Bianchi","year":"2016","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1016\/j.xfre.2023.02.012_bib8","doi-asserted-by":"crossref","first-page":"345","DOI":"10.1210\/jc.2015-3201","article-title":"Two consecutive live births in woman with 17-alpha-hydroxylase deficiency by frozen-thaw embryo transfer under hormone replacement endometrium preparation","volume":"101","author":"Kitajima","year":"2016","journal-title":"Gynecol Endocrinol Metab"},{"key":"10.1016\/j.xfre.2023.02.012_bib9","doi-asserted-by":"crossref","first-page":"6079","DOI":"10.1111\/cen.13549","article-title":"Successful infertility outcome in a woman with 17-alpha-hydroxylase deficiency","volume":"88","author":"Falhammar","year":"2018","journal-title":"Clin Endocrinol (Oxf)"},{"key":"10.1016\/j.xfre.2023.02.012_bib10","doi-asserted-by":"crossref","first-page":"1882","DOI":"10.1210\/clinem\/dgab222","article-title":"Successful delivery in 17,20-lyase deficiency","volume":"106","author":"Blumenfeld","year":"2021","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1016\/j.xfre.2023.02.012_bib11","doi-asserted-by":"crossref","first-page":"e2610","DOI":"10.1210\/clinem\/dgac029","article-title":"Phenotypic heterogeneity and fertility potential of patients with 17-hydroxylase\/17,20-lyase deficiency","volume":"107","author":"Xu","year":"2022","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1016\/j.xfre.2023.02.012_bib12","first-page":"751","article-title":"Successful assisted reproductive technology treatment for a woman with 46XX-17\u03b1-hydroxylase deficiency: A case report","volume":"54","author":"Zhang","year":"2022","journal-title":"Beijing Da Xue Xue Bao Yi Xue Ban"},{"key":"10.1016\/j.xfre.2023.02.012_bib13","doi-asserted-by":"crossref","first-page":"18076","DOI":"10.1016\/S0021-9258(19)84680-X","article-title":"Deletion of a phenylalanine in the N-terminal region of human cytochrome P-450(17 alpha) results in partial combined 17 alpha-hydroxylase\/17,20-lyase deficiency","volume":"264","author":"Yanase","year":"1989","journal-title":"J Biol Chem"},{"key":"10.1016\/j.xfre.2023.02.012_bib14","doi-asserted-by":"crossref","first-page":"693","DOI":"10.1210\/jcem-68-3-693","article-title":"In\u00a0vitro fertilization and primary embryonic cleavage are possible in 17 alpha-hydroxylase deficiency despite extremely low intrafollicular 17 beta-estradiol","volume":"68","author":"Rabinovici","year":"1989","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1016\/j.xfre.2023.02.012_bib16","doi-asserted-by":"crossref","first-page":"970","DOI":"10.1016\/S0015-0282(16)54308-8","article-title":"In\u00a0vitro fertilization as a diagnostic and therapeutic tool in a patient with partial 17,20-desmolase deficiency","volume":"55","author":"Pellicer","year":"1991","journal-title":"Fertil Steril"},{"key":"10.1016\/j.xfre.2023.02.012_bib15","doi-asserted-by":"crossref","first-page":"400","DOI":"10.1055\/s-0029-1211475","article-title":"Substitution with testosterone as aromatizable substrate for induction of follicular maturation, estradiol production and ovulation in a patient with 17 alpha-hydroxylase deficiency","volume":"104","author":"Neuwinger","year":"1996","journal-title":"Exp Clin Endocrinol Diabetes"},{"key":"10.1016\/j.xfre.2023.02.012_bib18","doi-asserted-by":"crossref","first-page":"1183","DOI":"10.1016\/S0015-0282(00)00500-8","article-title":"Induction of endometrial cycles and ovulation in a woman with combined 17alpha-hydroxylase\/17,20-lyase deficiency due to compound heterozygous mutations on the p45017alpha gene","volume":"73","author":"Matsuzaki","year":"2000","journal-title":"Fertil Steril"},{"key":"10.1016\/j.xfre.2023.02.012_bib17","doi-asserted-by":"crossref","first-page":"777","DOI":"10.1093\/oxfordjournals.humrep.a136984","article-title":"Progesterone versus dehydrogesterone as replacement therapy in women with premature ovarian failure","volume":"4","author":"Pellicer","year":"1989","journal-title":"Hum Reprod"}],"container-title":["F&amp;S Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2666334123000314?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2666334123000314?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,12]],"date-time":"2025-11-12T21:05:48Z","timestamp":1762981548000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2666334123000314"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,6]]},"references-count":18,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2023,6]]}},"alternative-id":["S2666334123000314"],"URL":"https:\/\/doi.org\/10.1016\/j.xfre.2023.02.012","relation":{},"ISSN":["2666-3341"],"issn-type":[{"type":"print","value":"2666-3341"}],"subject":[],"published":{"date-parts":[[2023,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Pregnancy outcomes in in vitro fertilization in 17-alpha-hydroxylase deficiency","name":"articletitle","label":"Article Title"},{"value":"F&S Reports","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.xfre.2023.02.012","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2023 The Authors. Published by Elsevier Inc. on behalf of American Society for Reproductive Medicine.","name":"copyright","label":"Copyright"}]}}