{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,27]],"date-time":"2026-04-27T21:01:11Z","timestamp":1777323671508,"version":"3.51.4"},"reference-count":13,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2026,2,1]],"date-time":"2026-02-01T00:00:00Z","timestamp":1769904000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,2,1]],"date-time":"2026-02-01T00:00:00Z","timestamp":1769904000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,12,3]],"date-time":"2025-12-03T00:00:00Z","timestamp":1764720000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["fertstertreports.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["F&S Reports"],"published-print":{"date-parts":[[2026,2]]},"DOI":"10.1016\/j.xfre.2025.12.003","type":"journal-article","created":{"date-parts":[[2025,12,6]],"date-time":"2025-12-06T23:30:29Z","timestamp":1765063829000},"page":"25-30","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":1,"title":["Second-trimester pregnancy loss after in vitro fertilization: risk factors and risk reduction"],"prefix":"10.1016","volume":"7","author":[{"given":"Sarah","family":"Rubin","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Olivia","family":"Nussbaum","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kaleb","family":"Noruzi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Autumn","family":"Brewer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shmuel","family":"Sashitzky","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alexis","family":"Greene","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Martin","family":"Keltz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.xfre.2025.12.003_bib1","doi-asserted-by":"crossref","first-page":"581.e1","DOI":"10.1016\/j.ajog.2007.09.016","article-title":"Second-trimester loss and subsequent pregnancy outcomes: what is the real risk?","volume":"197","author":"Edlow","year":"2007","journal-title":"Am J Obstet Gynecol"},{"key":"10.1016\/j.xfre.2025.12.003_bib2","doi-asserted-by":"crossref","first-page":"1168","DOI":"10.1016\/j.ajog.2005.12.017","article-title":"Risk factors for previable premature rupture of membranes or advanced cervical dilation: a case control study","volume":"194","author":"Kilpatrick","year":"2006","journal-title":"Am J Obstet Gynecol"},{"key":"10.1016\/j.xfre.2025.12.003_bib3","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1080\/10647440300025508","article-title":"Second-trimester pregnancy loss at an urban hospital","volume":"11","author":"Heller","year":"2003","journal-title":"Infect Dis Obstet Gynecol"},{"key":"10.1016\/j.xfre.2025.12.003_bib4","doi-asserted-by":"crossref","first-page":"963","DOI":"10.1034\/j.1600-0412.2000.079011963.x","article-title":"High prevalence of the prothrombin gene mutation in women with intrauterine growth retardation, abruptio placentae and second trimester loss","volume":"79","author":"Kupferminc","year":"2000","journal-title":"Acta Obstet Gynecol Scand"},{"key":"10.1016\/j.xfre.2025.12.003_bib5","doi-asserted-by":"crossref","first-page":"477","DOI":"10.1093\/molehr\/gah204","article-title":"A polymorphism in the MTHFD1 gene increases a mother's risk of having an unexplained second trimester pregnancy loss","volume":"11","author":"Parle-McDermott","year":"2005","journal-title":"Mol Hum Reprod"},{"key":"10.1016\/j.xfre.2025.12.003_bib6","first-page":"57","article-title":"The comparison of predictive value of cervical length in singleton spontaneous preterm labor with in vitro fertilization pregnancies: a cohort study","volume":"19","author":"Jafari","year":"2021","journal-title":"Int J Reprod Biomed"},{"key":"10.1016\/j.xfre.2025.12.003_bib7","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1016\/j.ejogrb.2014.03.002","article-title":"Preterm delivery risk factors in singletons born after in vitro fertilization procedures","volume":"176","author":"Ban Frangez","year":"2014","journal-title":"Eur J Obstet Gynecol Reprod Biol"},{"key":"10.1016\/j.xfre.2025.12.003_bib8","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1016\/S0015-0282(03)01377-3","article-title":"Increased second trimester pregnancy loss following in vitro fertilization (IVF)","volume":"80","author":"Keltz","year":"2003","journal-title":"Fertil Steril"},{"key":"10.1016\/j.xfre.2025.12.003_bib9","doi-asserted-by":"crossref","first-page":"621","DOI":"10.1097\/AOG.0000000000000667","article-title":"Factors associated with second-trimester pregnancy loss in women with normal uterine anatomy undergoing in vitro fertilization","volume":"125","author":"Hawkins Bressler","year":"2015","journal-title":"Obstet Gynecol"},{"key":"10.1016\/j.xfre.2025.12.003_bib10","first-page":"651","article-title":"Reproductive Medicine and the Practice Committee for the Society for Assisted Reproductive Technologies. Electronic address: ASRM@asrm.org. Guidance on the limits to the number of embryos to transfer: a committee opinion","volume":"116","year":"2001","journal-title":"Fertil Steril"},{"key":"10.1016\/j.xfre.2025.12.003_bib11","doi-asserted-by":"crossref","first-page":"1347","DOI":"10.1007\/s00404-020-05863-1","article-title":"The association between operative hysteroscopy prior to assisted reproductive technology and cervical insufficiency in second trimester","volume":"303","author":"G\u00f6k\u00e7e","year":"2021","journal-title":"Arch Gynecol Obstet"},{"key":"10.1016\/j.xfre.2025.12.003_bib12","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1016\/j.fertnstert.2023.01.022","article-title":"Racial disparities in uterine fibroids and endometriosis: a systematic review and application of social, structural, and political context","volume":"119","author":"Katon","year":"2023","journal-title":"Fertil Steril"},{"issue":"375","key":"10.1016\/j.xfre.2025.12.003_bib13","first-page":"e1","article-title":"Multicenter randomized trial of cerclage for preterm birth prevention in high-risk women with shortened midtrimester cervical length","volume":"201","author":"Owen","year":"2009","journal-title":"Am J Obstet Gynecol"}],"container-title":["F&S Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2666334125001771?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2666334125001771?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,2,10]],"date-time":"2026-02-10T20:45:13Z","timestamp":1770756313000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2666334125001771"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,2]]},"references-count":13,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2026,2]]}},"alternative-id":["S2666334125001771"],"URL":"https:\/\/doi.org\/10.1016\/j.xfre.2025.12.003","relation":{},"ISSN":["2666-3341"],"issn-type":[{"value":"2666-3341","type":"print"}],"subject":[],"published":{"date-parts":[[2026,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Second-trimester pregnancy loss after in vitro fertilization: risk factors and risk reduction","name":"articletitle","label":"Article Title"},{"value":"F&S Reports","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.xfre.2025.12.003","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 The Authors. Published by Elsevier Inc. on behalf of American Society for Reproductive Medicine.","name":"copyright","label":"Copyright"}]}}