{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,2]],"date-time":"2026-07-02T16:16:44Z","timestamp":1783009004450,"version":"3.54.5"},"reference-count":56,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2024,5,1]],"date-time":"2024-05-01T00:00:00Z","timestamp":1714521600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,5,1]],"date-time":"2024-05-01T00:00:00Z","timestamp":1714521600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2023,10,27]],"date-time":"2023-10-27T00:00:00Z","timestamp":1698364800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["fertstertscience.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["F&S Science"],"published-print":{"date-parts":[[2024,5]]},"DOI":"10.1016\/j.xfss.2023.10.003","type":"journal-article","created":{"date-parts":[[2023,10,29]],"date-time":"2023-10-29T05:00:36Z","timestamp":1698555636000},"page":"141-153","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":3,"title":["Effects of maternal taxane chemotherapy exposure on daughters\u2019 ovarian reserve and fertility potential"],"prefix":"10.1016","volume":"5","author":[{"given":"Julienne","family":"Chaqour","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6959-2804","authenticated-orcid":false,"given":"Meghan C.H.","family":"Ozcan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Payton","family":"De La Cruz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Morgan F.","family":"Woodman-Sousa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Julia N.","family":"McAdams","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7102-817X","authenticated-orcid":false,"given":"Kathryn J.","family":"Grive","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.xfss.2023.10.003_bib1","doi-asserted-by":"crossref","first-page":"571","DOI":"10.1016\/j.jare.2015.12.004","article-title":"Lung cancer during pregnancy: a narrative review","volume":"7","author":"Mitrou","year":"2016","journal-title":"J Adv Res"},{"key":"10.1016\/j.xfss.2023.10.003_bib2","doi-asserted-by":"crossref","first-page":"e4899","DOI":"10.1097\/MD.0000000000004899","article-title":"Chemotherapy against cancer during pregnancy: a systematic review on neonatal outcomes","volume":"95","author":"Esposito","year":"2016","journal-title":"Med (Baltim)"},{"key":"10.1016\/j.xfss.2023.10.003_bib3","doi-asserted-by":"crossref","first-page":"545","DOI":"10.1200\/OP.20.00077","article-title":"Multidisciplinary management of cancer during pregnancy","volume":"16","author":"Silverstein","year":"2020","journal-title":"JCO Oncol Pract"},{"key":"10.1016\/j.xfss.2023.10.003_bib4","first-page":"278","article-title":"Chemotherapy during pregnancy: pharmacokinetics and impact on foetal neurological development","volume":"2","author":"Van Calsteren","year":"2010","journal-title":"Facts Views Vis Obgyn"},{"key":"10.1016\/j.xfss.2023.10.003_bib5","doi-asserted-by":"crossref","first-page":"580","DOI":"10.1097\/CCO.0b013e328354e754","article-title":"Chemotherapy during pregnancy","volume":"24","author":"Amant","year":"2012","journal-title":"Curr Opin Oncol"},{"key":"10.1016\/j.xfss.2023.10.003_bib6","doi-asserted-by":"crossref","first-page":"329","DOI":"10.1007\/s40272-013-0040-6","article-title":"Effects of fetal exposure to maternal chemotherapy","volume":"15","author":"Dekrem","year":"2013","journal-title":"Paediatr Drugs"},{"key":"10.1016\/j.xfss.2023.10.003_bib7","doi-asserted-by":"crossref","DOI":"10.1001\/jamanetworkopen.2021.13180","article-title":"Association of chemotherapy timing in pregnancy with congenital malformation","volume":"4","author":"van Gerwen","year":"2021","journal-title":"JAMA Netw Open"},{"key":"10.1016\/j.xfss.2023.10.003_bib8","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1093\/jncimonographs\/lgi009","article-title":"Children exposed to chemotherapy in utero","volume":"2005","author":"Gwyn","year":"2005","journal-title":"J Natl Cancer Inst Monogr"},{"key":"10.1016\/j.xfss.2023.10.003_bib9","doi-asserted-by":"crossref","first-page":"1145","DOI":"10.1001\/jamaoncol.2015.2413","article-title":"Breast cancer diagnosed during pregnancy: adapting recent advances in breast cancer care for pregnant patients","volume":"1","author":"Loibl","year":"2015","journal-title":"JAMA Oncol"},{"key":"10.1016\/j.xfss.2023.10.003_bib10","doi-asserted-by":"crossref","first-page":"193","DOI":"10.2174\/1568009033481967","article-title":"Taxanes: microtubule and centrosome targets, and cell cycle dependent mechanisms of action","volume":"3","author":"Abal","year":"2003","journal-title":"Curr Cancer Drug Targets"},{"key":"10.1016\/j.xfss.2023.10.003_bib11","doi-asserted-by":"crossref","first-page":"2092","DOI":"10.1158\/1535-7163.MCT-14-0265","article-title":"Antiproliferative mechanism of action of the novel taxane cabazitaxel as compared with the parent compound docetaxel in MCF7 breast cancer cells","volume":"13","author":"Azarenko","year":"2014","journal-title":"Mol Cancer Ther"},{"key":"10.1016\/j.xfss.2023.10.003_bib12","series-title":"StatPearls [Internet]","article-title":"Cancer Chemotherapy","author":"Amjad","year":"2023"},{"key":"10.1016\/j.xfss.2023.10.003_bib13","doi-asserted-by":"crossref","first-page":"822","DOI":"10.1002\/cncr.11578","article-title":"Measuring the side effects of taxane therapy in oncology: the functional assessment of cancer therapy-taxane (FACT-taxane)","volume":"98","author":"Cella","year":"2003","journal-title":"Cancer"},{"key":"10.1016\/j.xfss.2023.10.003_bib14","doi-asserted-by":"crossref","first-page":"673","DOI":"10.1093\/humupd\/dmz027","article-title":"Ovarian damage from chemotherapy and current approaches to its protection","volume":"25","author":"Spears","year":"2019","journal-title":"Hum Reprod Update"},{"key":"10.1016\/j.xfss.2023.10.003_bib15","doi-asserted-by":"crossref","first-page":"525","DOI":"10.1093\/humupd\/dms022","article-title":"How do chemotherapeutic agents damage the ovary?","volume":"18","author":"Morgan","year":"2012","journal-title":"Hum Reprod Update"},{"key":"10.1016\/j.xfss.2023.10.003_bib16","doi-asserted-by":"crossref","first-page":"948","DOI":"10.1093\/molehr\/gau057","article-title":"Docetaxel induces moderate ovarian toxicity in mice, primarily affecting granulosa cells of early growing follicles","volume":"20","author":"Lopes","year":"2014","journal-title":"Mol Hum Reprod"},{"key":"10.1016\/j.xfss.2023.10.003_bib17","doi-asserted-by":"crossref","first-page":"2554","DOI":"10.1242\/dev.125211","article-title":"The developmental origins of the mammalian ovarian reserve","volume":"142","author":"Grive","year":"2015","journal-title":"Development"},{"key":"10.1016\/j.xfss.2023.10.003_bib18","doi-asserted-by":"crossref","first-page":"843","DOI":"10.1002\/mrd.23401","article-title":"Pathways coordinating oocyte attrition and abundance during mammalian ovarian reserve establishment","volume":"87","author":"Grive","year":"2020","journal-title":"Mol Reprod Dev"},{"issue":"Suppl 6","key":"10.1016\/j.xfss.2023.10.003_bib19","doi-asserted-by":"crossref","first-page":"vi160","DOI":"10.1093\/annonc\/mdt199","article-title":"Cancer, pregnancy and fertility: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up","volume":"24","author":"Peccatori","year":"2013","journal-title":"Ann Oncol"},{"key":"10.1016\/j.xfss.2023.10.003_bib20","doi-asserted-by":"crossref","first-page":"3016","DOI":"10.1093\/annonc\/mds170","article-title":"Maternal and fetal outcomes of taxane chemotherapy in breast and ovarian cancer during pregnancy: case series and review of the literature","volume":"23","author":"Cardonick","year":"2012","journal-title":"Ann Oncol"},{"key":"10.1016\/j.xfss.2023.10.003_bib21","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1016\/j.clbc.2012.09.014","article-title":"Taxanes for breast cancer during pregnancy: a systematic review","volume":"13","author":"Zagouri","year":"2013","journal-title":"Clin Breast Cancer"},{"key":"10.1016\/j.xfss.2023.10.003_bib22","doi-asserted-by":"crossref","first-page":"28","DOI":"10.14740\/wjon1177","article-title":"Cancer during pregnancy: the oncologist overview","volume":"10","author":"Hepner","year":"2019","journal-title":"World J Oncol"},{"key":"10.1016\/j.xfss.2023.10.003_bib23","doi-asserted-by":"crossref","first-page":"1238","DOI":"10.3390\/cancers13061238","article-title":"Cancer during pregnancy: a review of preclinical and clinical transplacental transfer of anticancer agents","volume":"13","author":"Benoit","year":"2021","journal-title":"Cancers (Basel)"},{"key":"10.1016\/j.xfss.2023.10.003_bib24","doi-asserted-by":"crossref","first-page":"1183","DOI":"10.2169\/internalmedicine.5089-20","article-title":"A multicenter study of docetaxel at a dose of 100 mg\/m2 in Japanese patients with advanced or recurrent breast cancer","volume":"60","author":"Hirata","year":"2021","journal-title":"Intern Med"},{"issue":"Suppl 17","key":"10.1016\/j.xfss.2023.10.003_bib25","first-page":"S17","article-title":"Weekly high-dose paclitaxel in metastatic and locally advanced breast cancer: a preliminary report","volume":"24","author":"Akerley","year":"1997","journal-title":"Semin Oncol"},{"key":"10.1016\/j.xfss.2023.10.003_bib26","doi-asserted-by":"crossref","first-page":"27","DOI":"10.4103\/0976-0105.177703","article-title":"A simple practice guide for dose conversion between animals and human","volume":"7","author":"Nair","year":"2016","journal-title":"J Basic Clin Pharm"},{"key":"10.1016\/j.xfss.2023.10.003_bib27","first-page":"500","article-title":"The requirement of ubiquitin C-terminal hydrolase L1 (UCHL1) in mouse ovarian development and fertility","volume":"107","author":"Woodman","year":"2022","journal-title":"bioRxiv"},{"key":"10.1016\/j.xfss.2023.10.003_bib28","first-page":"471","article-title":"Superovulation strategies for 6 commonly used mouse strains","volume":"50","author":"Luo","year":"2011","journal-title":"J Am Assoc Lab Anim Sci"},{"key":"10.1016\/j.xfss.2023.10.003_bib29","first-page":"58","article-title":"Multioocyte follicles in adult mammalian ovaries","volume":"8","author":"Silva-Santos","year":"2011","journal-title":"Anim Reprod Sci"},{"key":"10.1016\/j.xfss.2023.10.003_bib30","doi-asserted-by":"crossref","first-page":"540","DOI":"10.1016\/j.rbmo.2012.01.023","article-title":"Anti-M\u00fcllerian hormone is highly expressed and secreted from cumulus granulosa cells of stimulated preovulatory immature and atretic oocytes","volume":"24","author":"Kedem-Dickman","year":"2012","journal-title":"Reprod Biomed Online"},{"key":"10.1016\/j.xfss.2023.10.003_bib31","doi-asserted-by":"crossref","first-page":"2333","DOI":"10.2217\/fon-2016-0176","article-title":"Chemotherapy-induced damage to ovary: mechanisms and clinical impact","volume":"12","author":"Bedoschi","year":"2016","journal-title":"Future Oncol"},{"key":"10.1016\/j.xfss.2023.10.003_bib32","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0144245","article-title":"Cisplatin induces overactivation of the dormant primordial follicle through PTEN\/AKT\/FOXO3a pathway which leads to loss of ovarian reserve in mice","volume":"10","author":"Chang","year":"2015","journal-title":"PLOS ONE"},{"key":"10.1016\/j.xfss.2023.10.003_bib33","doi-asserted-by":"crossref","DOI":"10.1126\/scitranslmed.3005402","article-title":"Cyclophosphamide triggers follicle activation and \u201dburnout\u201d; AS101 prevents follicle loss and preserves fertility","volume":"5","author":"Kalich-Philosoph","year":"2013","journal-title":"Sci Transl Med"},{"key":"10.1016\/j.xfss.2023.10.003_bib34","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0020087","article-title":"Inhibitory actions of anti-M\u00fcllerian hormone (AMH) on ovarian primordial follicle assembly","volume":"6","author":"Nilsson","year":"2011","journal-title":"PLOS ONE"},{"key":"10.1016\/j.xfss.2023.10.003_bib35","doi-asserted-by":"crossref","first-page":"795","DOI":"10.1093\/molehr\/gap073","article-title":"The primordial pool of follicles and nest breakdown in mammalian ovaries","volume":"15","author":"Tingen","year":"2009","journal-title":"Mol Hum Reprod"},{"key":"10.1016\/j.xfss.2023.10.003_bib36","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1095\/biolreprod.108.074898","article-title":"Prepubertal primordial follicle loss in mice is not due to classical apoptotic pathways","volume":"81","author":"Tingen","year":"2009","journal-title":"Biol Reprod"},{"key":"10.1016\/j.xfss.2023.10.003_bib37","doi-asserted-by":"crossref","first-page":"5342","DOI":"10.3390\/ijms20215342","article-title":"The impact of chemotherapy on the ovaries: molecular aspects and the prevention of ovarian damage","volume":"20","author":"Sonigo","year":"2019","journal-title":"Int J Mol Sci"},{"key":"10.1016\/j.xfss.2023.10.003_bib38","doi-asserted-by":"crossref","first-page":"11513","DOI":"10.1073\/pnas.2001124117","article-title":"Oocytes can efficiently repair DNA double-strand breaks to restore genetic integrity and protect offspring health","volume":"117","author":"Stringer","year":"2020","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.xfss.2023.10.003_bib39","series-title":"Human reproduction: conception and contraception","first-page":"53","author":"Franchi","year":"1973"},{"key":"10.1016\/j.xfss.2023.10.003_bib40","doi-asserted-by":"crossref","first-page":"1469","DOI":"10.1093\/humrep\/deab065","article-title":"Reduced FSH and LH action: implications for medically assisted reproduction","volume":"36","author":"Bosch","year":"2021","journal-title":"Hum Reprod"},{"key":"10.1016\/j.xfss.2023.10.003_bib41","series-title":"StatPearls [Internet]","article-title":"Physiology, Follicle Stimulating Hormone","author":"Orlowski","year":"2023"},{"key":"10.1016\/j.xfss.2023.10.003_bib42","doi-asserted-by":"crossref","first-page":"190","DOI":"10.1016\/j.tox.2012.07.015","article-title":"Involvement of hypothalamic cyclooxygenase-2, interleukin-1\u03b2 and melanocortin in the development of docetaxel-induced anorexia in rats","volume":"302","author":"Yamamoto","year":"2012","journal-title":"Toxicology"},{"key":"10.1016\/j.xfss.2023.10.003_bib43","doi-asserted-by":"crossref","first-page":"993","DOI":"10.1095\/biolreprod.105.049049","article-title":"Mechanisms for pulsatile regulation of the gonadotropin subunit genes by GNRH1","volume":"74","author":"Ferris","year":"2006","journal-title":"Biol Reprod"},{"key":"10.1016\/j.xfss.2023.10.003_bib44","doi-asserted-by":"crossref","first-page":"196","DOI":"10.6065\/apem.2013.18.4.196","article-title":"Basal luteinizing hormone and follicular stimulating hormone: is it sufficient for the diagnosis of precocious puberty in girls?","volume":"18","author":"Lee","year":"2013","journal-title":"Ann Pediatr Endocrinol Metab"},{"key":"10.1016\/j.xfss.2023.10.003_bib45","first-page":"244","article-title":"Gonadotropin-releasing hormone stimulation test for precocious puberty","volume":"31","author":"Kim","year":"2011","journal-title":"Korean J Lab Med"},{"key":"10.1016\/j.xfss.2023.10.003_bib46","doi-asserted-by":"crossref","first-page":"2246","DOI":"10.1002\/jbmr.3856","article-title":"Estradiol and follicle-stimulating hormone as predictors of onset of menopause transition-related bone loss in Pre- and perimenopausal women","volume":"34","author":"Shieh","year":"2019","journal-title":"J Bone Miner Res"},{"key":"10.1016\/j.xfss.2023.10.003_bib47","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.canep.2018.07.001","article-title":"Transgenerational effects of chemotherapy: both male and female children born to women exposed to chemotherapy have fewer children","volume":"56","author":"Patel","year":"2018","journal-title":"Cancer Epidemiol"},{"key":"10.1016\/j.xfss.2023.10.003_bib48","doi-asserted-by":"crossref","DOI":"10.1016\/j.isci.2022.105570","article-title":"Examination of generational impacts of adolescent chemotherapy: ifosfamide and potential for epigenetic transgenerational inheritance","volume":"25","author":"Thompson","year":"2022","journal-title":"iScience"},{"key":"10.1016\/j.xfss.2023.10.003_bib49","doi-asserted-by":"crossref","first-page":"495","DOI":"10.1093\/oxfordjournals.annonc.a058903","article-title":"Paclitaxel (Taxol) and docetaxel (Taxotere): not simply two of a kind","volume":"5","author":"Verweij","year":"1994","journal-title":"Ann Oncol"},{"issue":"Suppl 2","key":"10.1016\/j.xfss.2023.10.003_bib50","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1634\/theoncologist.9-suppl_2-3","article-title":"Preclinical pharmacology of the taxanes: implications of the differences","volume":"9","author":"Gligorov","year":"2004","journal-title":"Oncologist"},{"key":"10.1016\/j.xfss.2023.10.003_bib51","doi-asserted-by":"crossref","first-page":"423","DOI":"10.1055\/s-2006-951301","article-title":"Role of human placental efflux transporter P-glycoprotein in the transfer of buprenorphine, levo-alpha-acetylmethadol, and paclitaxel","volume":"23","author":"Nekhayeva","year":"2006","journal-title":"Am J Perinatol"},{"key":"10.1016\/j.xfss.2023.10.003_bib52","doi-asserted-by":"crossref","first-page":"514.e1","DOI":"10.1016\/j.ajog.2012.10.007","article-title":"Comparative transplacental transfer of taxanes using the human perfused cotyledon placental model","volume":"207","author":"Berveiller","year":"2012","journal-title":"Am J Obstet Gynecol"},{"key":"10.1016\/j.xfss.2023.10.003_bib53","doi-asserted-by":"crossref","first-page":"232","DOI":"10.1080\/10826076.2018.1436068","article-title":"Determination of the transplacental transfer of paclitaxel and Antipyrine by high performance liquid chromatography coupled with photodiode array detector","volume":"41","author":"Ali","year":"2018","journal-title":"J Liq Chromatogr Relat Technol"},{"key":"10.1016\/j.xfss.2023.10.003_bib54","doi-asserted-by":"crossref","first-page":"404","DOI":"10.1136\/ijgc-2018-000061","article-title":"Management of cancer during pregnancy and current evidence of obstetric, neonatal and pediatric outcome: a review article","volume":"29","author":"Maggen","year":"2019","journal-title":"Int J Gynecol Cancer"},{"key":"10.1016\/j.xfss.2023.10.003_bib55","doi-asserted-by":"crossref","first-page":"314","DOI":"10.1136\/ijgc-2020-001776","article-title":"Management of pregnancy in women with cancer","volume":"31","author":"Wolters","year":"2021","journal-title":"Int J Gynecol Cancer"},{"key":"10.1016\/j.xfss.2023.10.003_bib56","doi-asserted-by":"crossref","first-page":"5480","DOI":"10.1182\/bloodadvances.2023010090","article-title":"An international real-world analysis of relapsed\/refractory lymphoma occurring during pregnancy","volume":"7","author":"Farooq","year":"2023","journal-title":"Blood Adv"}],"container-title":["F&S Science"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2666335X23000599?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2666335X23000599?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,10,18]],"date-time":"2024-10-18T13:31:35Z","timestamp":1729258295000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2666335X23000599"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,5]]},"references-count":56,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2024,5]]}},"alternative-id":["S2666335X23000599"],"URL":"https:\/\/doi.org\/10.1016\/j.xfss.2023.10.003","relation":{},"ISSN":["2666-335X"],"issn-type":[{"value":"2666-335X","type":"print"}],"subject":[],"published":{"date-parts":[[2024,5]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Effects of maternal taxane chemotherapy exposure on daughters\u2019 ovarian reserve and fertility potential","name":"articletitle","label":"Article Title"},{"value":"F&S Science","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.xfss.2023.10.003","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2023 The Authors. Published by Elsevier Inc. on behalf of American Society for Reproductive Medicine.","name":"copyright","label":"Copyright"}]}}