{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,16]],"date-time":"2025-05-16T04:02:04Z","timestamp":1747368124159,"version":"3.40.5"},"reference-count":56,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2025,5,1]],"date-time":"2025-05-01T00:00:00Z","timestamp":1746057600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,5,1]],"date-time":"2025-05-01T00:00:00Z","timestamp":1746057600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["P50HD098580","R01ES034753"],"award-info":[{"award-number":["P50HD098580","R01ES034753"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000009","name":"Foundation for the National Institutes of Health","doi-asserted-by":"publisher","award":["P50HD098580"],"award-info":[{"award-number":["P50HD098580"]}],"id":[{"id":"10.13039\/100000009","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["fertstertscience.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["F&S Science"],"published-print":{"date-parts":[[2025,5]]},"DOI":"10.1016\/j.xfss.2025.01.005","type":"journal-article","created":{"date-parts":[[2025,2,27]],"date-time":"2025-02-27T20:32:40Z","timestamp":1740688360000},"page":"202-212","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"title":["Stearoyl\u2013coenzyme A desaturase enhances cell survival in human uterine leiomyoma"],"prefix":"10.1016","volume":"6","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3084-4613","authenticated-orcid":false,"given":"Allison S.","family":"Komorowski","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"John S.","family":"Coon V","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Melania","family":"Anton","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Azna","family":"Zuberi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Olivia","family":"Sotos","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Serdar E.","family":"Bulun","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1600-6568","authenticated-orcid":false,"given":"Ping","family":"Yin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.xfss.2025.01.005_bib1","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1016\/j.bpobgyn.2015.11.016","article-title":"Role of medical management for uterine leiomyomas","volume":"34","author":"Kashani","year":"2016","journal-title":"Best Pract Res Clin Obstet Gynaecol"},{"key":"10.1016\/j.xfss.2025.01.005_bib2","doi-asserted-by":"crossref","first-page":"100","DOI":"10.1067\/mob.2003.99","article-title":"High cumulative incidence of uterine leiomyoma in black and white women: ultrasound evidence","volume":"188","author":"Baird","year":"2003","journal-title":"Am J Obstet Gynecol"},{"key":"10.1016\/j.xfss.2025.01.005_bib3","doi-asserted-by":"crossref","first-page":"1344","DOI":"10.1056\/NEJMra1209993","article-title":"Uterine fibroids","volume":"369","author":"Bulun","year":"2013","journal-title":"N Engl J Med"},{"key":"10.1016\/j.xfss.2025.01.005_bib4","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1016\/j.ajog.2015.03.019","article-title":"The direct and indirect costs of uterine fibroid tumors: a systematic review of the literature between 2000 and 2013","volume":"213","author":"Soliman","year":"2015","journal-title":"Am J Obstet Gynecol"},{"key":"10.1016\/j.xfss.2025.01.005_bib5","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1007\/s10397-014-0842-8","article-title":"The risk of uterine rupture after myomectomy: a systematic review of the literature and meta-analysis","volume":"11","author":"Claeys","year":"2014","journal-title":"Gynecol Surg"},{"key":"10.1016\/j.xfss.2025.01.005_bib6","doi-asserted-by":"crossref","DOI":"10.3389\/fsurg.2023.1151901","article-title":"Myomectomy in infertile women: more harm than good?","volume":"10","author":"Mercorio","year":"2023","journal-title":"Front Surg"},{"key":"10.1016\/j.xfss.2025.01.005_bib7","doi-asserted-by":"crossref","DOI":"10.1126\/science.aaw5473","article-title":"Metabolic reprogramming and cancer progression","volume":"368","author":"Faubert","year":"2020","journal-title":"Science"},{"key":"10.1016\/j.xfss.2025.01.005_bib8","doi-asserted-by":"crossref","first-page":"2726","DOI":"10.1194\/jlr.M600299-JLR200","article-title":"Disruption of endoplasmic reticulum structure and integrity in lipotoxic cell death","volume":"47","author":"Borradaile","year":"2006","journal-title":"J Lipid Res"},{"key":"10.1016\/j.xfss.2025.01.005_bib9","doi-asserted-by":"crossref","first-page":"262","DOI":"10.1016\/0014-4800(77)90035-1","article-title":"Saturated free fatty acid toxicity. II. Lipid accumulation, ultrastructural alterations, and toxicity in mammalian cells in culture","volume":"27","author":"Gordon","year":"1977","journal-title":"Exp Mol Pathol"},{"key":"10.1016\/j.xfss.2025.01.005_bib10","doi-asserted-by":"crossref","first-page":"E28","DOI":"10.1152\/ajpendo.90897.2008","article-title":"Biochemical and physiological function of stearoyl-CoA desaturase","volume":"297","author":"Paton","year":"2009","journal-title":"Am J Physiol Endocrinol Metab"},{"key":"10.1016\/j.xfss.2025.01.005_bib11","doi-asserted-by":"crossref","first-page":"1549","DOI":"10.1016\/S0022-2275(20)33401-5","article-title":"Regulation of stearoyl-CoA desaturase by polyunsaturated fatty acids and cholesterol","volume":"40","author":"Ntambi","year":"1999","journal-title":"J Lipid Res"},{"key":"10.1016\/j.xfss.2025.01.005_bib12","doi-asserted-by":"crossref","first-page":"1682","DOI":"10.1158\/0008-5472.CAN-21-4044","article-title":"Targeting stearoyl-CoA desaturase in solid tumors","volume":"82","author":"Kubota","year":"2022","journal-title":"Cancer Res"},{"key":"10.1016\/j.xfss.2025.01.005_bib13","doi-asserted-by":"crossref","first-page":"5959","DOI":"10.1038\/srep05959","article-title":"Significantly increased monounsaturated lipids relative to polyunsaturated lipids in six types of cancer microenvironment are observed by mass spectrometry imaging","volume":"4","author":"Guo","year":"2014","journal-title":"Sci Rep"},{"key":"10.1016\/j.xfss.2025.01.005_bib14","doi-asserted-by":"crossref","first-page":"2368","DOI":"10.1158\/1078-0432.CCR-12-3249","article-title":"Stearoyl-CoA desaturase 1 is a novel molecular therapeutic target for clear cell renal cell carcinoma","volume":"19","author":"von Roemeling","year":"2013","journal-title":"Clin Cancer Res"},{"key":"10.1016\/j.xfss.2025.01.005_bib15","doi-asserted-by":"crossref","first-page":"12064","DOI":"10.18632\/oncotarget.24304","article-title":"Targeting stearoyl-CoA desaturase 1 to repress endometrial cancer progression","volume":"9","author":"Li","year":"2018","journal-title":"Oncotarget"},{"key":"10.1016\/j.xfss.2025.01.005_bib16","doi-asserted-by":"crossref","first-page":"2064","DOI":"10.1111\/jcmm.14114","article-title":"Inhibition of stearoyl CoA desaturase-1 activity suppresses tumour progression and improves prognosis in human bladder cancer","volume":"23","author":"Piao","year":"2019","journal-title":"J Cell Mol Med"},{"key":"10.1016\/j.xfss.2025.01.005_bib17","doi-asserted-by":"crossref","first-page":"E697","DOI":"10.1210\/jc.2014-2764","article-title":"Aberrant lipid metabolism in anaplastic thyroid carcinoma reveals stearoyl CoA desaturase 1 as a novel therapeutic target","volume":"100","author":"von Roemeling","year":"2015","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1016\/j.xfss.2025.01.005_bib18","article-title":"High expression of stearoyl-CoA desaturase 1 predicts poor prognosis in patients with clear-cell renal cell carcinoma","volume":"11","author":"Wang","year":"2016","journal-title":"PLoS One"},{"key":"10.1016\/j.xfss.2025.01.005_bib19","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1007\/s11010-018-3306-z","article-title":"Increased expression of the gene encoding stearoyl-CoA desaturase 1 in human bladder cancer","volume":"447","author":"Presler","year":"2018","journal-title":"Mol Cell Biochem"},{"key":"10.1016\/j.xfss.2025.01.005_bib20","doi-asserted-by":"crossref","first-page":"1825","DOI":"10.1038\/s41591-021-01495-3","article-title":"Aramchol in patients with nonalcoholic steatohepatitis: a randomized, double-blind, placebo-controlled phase 2b trial","volume":"27","author":"Ratziu","year":"2021","journal-title":"Nat Med"},{"key":"10.1016\/j.xfss.2025.01.005_bib21","doi-asserted-by":"crossref","first-page":"1551","DOI":"10.1158\/1541-7786.MCR-11-0126","article-title":"Cancer cell dependence on unsaturated fatty acids implicates stearoyl-CoA desaturase as a target for cancer therapy","volume":"9","author":"Roongta","year":"2011","journal-title":"Mol Cancer Res"},{"key":"10.1016\/j.xfss.2025.01.005_bib22","doi-asserted-by":"crossref","first-page":"74","DOI":"10.1002\/ana.25920","article-title":"A stearoyl-coenzyme A desaturase inhibitor prevents multiple Parkinson disease phenotypes in \u03b1-synuclein mice","volume":"89","author":"Nuber","year":"2021","journal-title":"Ann Neurol"},{"key":"10.1016\/j.xfss.2025.01.005_bib23","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0033823","article-title":"SCD1 inhibition causes cancer cell death by depleting mono-unsaturated fatty acids","volume":"7","author":"Mason","year":"2012","journal-title":"PLoS One"},{"key":"10.1016\/j.xfss.2025.01.005_bib24","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0011394","article-title":"Inhibition of stearoylCoA desaturase activity blocks cell cycle progression and induces programmed cell death in lung cancer cells","volume":"5","author":"Hess","year":"2010","journal-title":"PLoS One"},{"key":"10.1016\/j.xfss.2025.01.005_bib25","doi-asserted-by":"crossref","first-page":"252","DOI":"10.1126\/science.1208930","article-title":"MED12, the mediator complex subunit 12 gene, is mutated at high frequency in uterine leiomyomas","volume":"334","author":"M\u00e4kinen","year":"2011","journal-title":"Science"},{"key":"10.1016\/j.xfss.2025.01.005_bib26","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0033251","article-title":"Whole exome sequencing in a random sample of North American women with leiomyomas identifies MED12 mutations in majority of uterine leiomyomas","volume":"7","author":"McGuire","year":"2012","journal-title":"PLoS One"},{"key":"10.1016\/j.xfss.2025.01.005_bib27","doi-asserted-by":"crossref","first-page":"1136","DOI":"10.1002\/humu.22612","article-title":"Mutations in Exon 1 highlight the role of MED12 in uterine leiomyomas","volume":"35","author":"K\u00e4mpj\u00e4rvi","year":"2014","journal-title":"Hum Mutat"},{"key":"10.1016\/j.xfss.2025.01.005_bib28","doi-asserted-by":"crossref","first-page":"3280","DOI":"10.1172\/JCI81534","article-title":"Med12 gain-of-function mutation causes leiomyomas and genomic instability","volume":"125","author":"Mittal","year":"2015","journal-title":"J Clin Invest"},{"key":"10.1016\/j.xfss.2025.01.005_bib29","doi-asserted-by":"crossref","first-page":"398","DOI":"10.1038\/s41586-021-03747-1","article-title":"Deficient H2A.Z deposition is associated with genesis of uterine leiomyoma","volume":"596","author":"Berta","year":"2021","journal-title":"Nature"},{"key":"10.1016\/j.xfss.2025.01.005_bib30","doi-asserted-by":"crossref","first-page":"4057","DOI":"10.1038\/s41467-023-39684-y","article-title":"Engineered MED12 mutations drive leiomyoma-like transcriptional and metabolic programs by altering the 3D genome compartmentalization","volume":"14","author":"Buyukcelebi","year":"2023","journal-title":"Nat Commun"},{"key":"10.1016\/j.xfss.2025.01.005_bib31","doi-asserted-by":"crossref","first-page":"719","DOI":"10.1097\/01.LAB.0000017499.51216.3E","article-title":"Immortalization of human uterine leiomyoma and myometrial cell lines after induction of telomerase activity: molecular and phenotypic characteristics","volume":"82","author":"Carney","year":"2002","journal-title":"Lab Invest"},{"key":"10.1016\/j.xfss.2025.01.005_bib32","doi-asserted-by":"crossref","first-page":"1842","DOI":"10.1210\/jc.2017-01585","article-title":"RANKL\/RANK pathway and its inhibitor RANK-Fc in uterine leiomyoma growth","volume":"103","author":"Ikhena","year":"2018","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1016\/j.xfss.2025.01.005_bib33","doi-asserted-by":"crossref","first-page":"2099","DOI":"10.1016\/j.stemcr.2021.07.013","article-title":"Progesterone receptor-DNA methylation crosstalk regulates depletion of uterine leiomyoma stem cells: a potential therapeutic target","volume":"16","author":"Liu","year":"2021","journal-title":"Stem Cell Reports"},{"key":"10.1016\/j.xfss.2025.01.005_bib34","doi-asserted-by":"crossref","DOI":"10.1172\/jci.insight.171305","article-title":"MED12 mutation activates the tryptophan\/kynurenine\/AHR pathway to promote growth of uterine leiomyomas","volume":"8","author":"Zuberi","year":"2023","journal-title":"JCI Insight"},{"key":"10.1016\/j.xfss.2025.01.005_bib35","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1007\/s11010-011-1211-9","article-title":"Saturated fatty acid induction of endoplasmic reticulum stress and apoptosis in human liver cells via the PERK\/ATF4\/CHOP signaling pathway","volume":"364","author":"Cao","year":"2012","journal-title":"Mol Cell Biochem"},{"key":"10.1016\/j.xfss.2025.01.005_bib36","doi-asserted-by":"crossref","first-page":"4069","DOI":"10.1016\/j.celrep.2019.11.077","article-title":"Integrated epigenome, exome, and transcriptome analyses reveal molecular subtypes and homeotic transformation in uterine fibroids","volume":"29","author":"George","year":"2019","journal-title":"Cell Rep"},{"key":"10.1016\/j.xfss.2025.01.005_bib37","doi-asserted-by":"crossref","DOI":"10.1016\/j.celrep.2021.108927","article-title":"Epigenomic tensor predicts disease subtypes and reveals constrained tumor evolution","volume":"34","author":"Leistico","year":"2021","journal-title":"Cell Rep"},{"key":"10.1016\/j.xfss.2025.01.005_bib38","doi-asserted-by":"crossref","first-page":"735","DOI":"10.1016\/j.bbrc.2005.05.013","article-title":"Characterization of HSCD5, a novel human stearoyl-CoA desaturase unique to primates","volume":"332","author":"Wang","year":"2005","journal-title":"Biochem Biophys Res Commun"},{"key":"10.1016\/j.xfss.2025.01.005_bib39","doi-asserted-by":"crossref","first-page":"2433","DOI":"10.1210\/en.2009-1225","article-title":"Progesterone is essential for maintenance and growth of uterine leiomyoma","volume":"151","author":"Ishikawa","year":"2010","journal-title":"Endocrinology"},{"key":"10.1016\/j.xfss.2025.01.005_bib40","doi-asserted-by":"crossref","first-page":"6","DOI":"10.1186\/s40170-016-0146-8","article-title":"Inhibition of fatty acid desaturation is detrimental to cancer cell survival in metabolically compromised environments","volume":"4","author":"Peck","year":"2016","journal-title":"Cancer Metab"},{"key":"10.1016\/j.xfss.2025.01.005_bib41","doi-asserted-by":"crossref","first-page":"1419","DOI":"10.1177\/1933719116689598","article-title":"Preperitoneal fat thicknesses, lipid profile, and oxidative status in women with uterine fibroids","volume":"24","author":"Vignini","year":"2017","journal-title":"Reprod Sci"},{"key":"10.1016\/j.xfss.2025.01.005_bib42","first-page":"716","article-title":"Relationship of uterine fibroids with lipid profile, anthropometric characteristics, subcutaneous and preperitoneal fat thickness","volume":"22","author":"Sharami","year":"2019","journal-title":"Arch Iran Med"},{"key":"10.1016\/j.xfss.2025.01.005_bib43","doi-asserted-by":"crossref","DOI":"10.1038\/s41598-021-89859-0","article-title":"Alterations in lipid profile upon uterine fibroids and its recurrence","volume":"11","author":"Tonoyan","year":"2021","journal-title":"Sci Rep"},{"key":"10.1016\/j.xfss.2025.01.005_bib44","doi-asserted-by":"crossref","first-page":"7143","DOI":"10.1002\/jcp.26537","article-title":"Omega-3 fatty acids modulate the lipid profile, membrane architecture, and gene expression of leiomyoma cells","volume":"233","author":"Islam","year":"2018","journal-title":"J Cell Physiol"},{"key":"10.1016\/j.xfss.2025.01.005_bib45","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1186\/s12967-018-1430-x","article-title":"The role of atorvastatin in suppressing tumor growth of uterine fibroids","volume":"16","author":"Shen","year":"2018","journal-title":"J Transl Med"},{"key":"10.1016\/j.xfss.2025.01.005_bib46","doi-asserted-by":"crossref","first-page":"735","DOI":"10.1016\/S0002-9378(16)32480-2","article-title":"Metabolic effects of progesterone","volume":"142","author":"Kalkhoff","year":"1982","journal-title":"Am J Obstet Gynecol"},{"key":"10.1016\/j.xfss.2025.01.005_bib47","first-page":"6256","article-title":"PLIN2 functions as a novel link between progesterone signaling and metabolism in uterine leiomyoma cells","volume":"104","author":"Okeigwe","year":"2019","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1016\/j.xfss.2025.01.005_bib48","doi-asserted-by":"crossref","first-page":"1221","DOI":"10.1016\/j.bbalip.2017.07.009","article-title":"The perilipin family of lipid droplet proteins: gatekeepers of intracellular lipolysis","volume":"1862","author":"Sztalryd","year":"2017","journal-title":"Biochim Biophys Acta Mol Cell Biol Lipids"},{"key":"10.1016\/j.xfss.2025.01.005_bib49","doi-asserted-by":"crossref","first-page":"2751","DOI":"10.1194\/jlr.M700359-JLR200","article-title":"Adipocyte differentiation-related protein reduces the lipid droplet association of adipose triglyceride lipase and slows triacylglycerol turnover","volume":"48","author":"Listenberger","year":"2007","journal-title":"J Lipid Res"},{"key":"10.1016\/j.xfss.2025.01.005_bib50","doi-asserted-by":"crossref","first-page":"96","DOI":"10.1016\/j.biochi.2013.08.026","article-title":"Perilipins: lipid droplet coat proteins adapted for tissue-specific energy storage and utilization, and lipid cytoprotection","volume":"96","author":"Sztalryd","year":"2014","journal-title":"Biochimie"},{"key":"10.1016\/j.xfss.2025.01.005_bib51","doi-asserted-by":"crossref","first-page":"687","DOI":"10.1146\/annurev-biochem-061009-102430","article-title":"Lipid droplets and cellular lipid metabolism","volume":"81","author":"Walther","year":"2012","journal-title":"Annu Rev Biochem"},{"key":"10.1016\/j.xfss.2025.01.005_bib52","doi-asserted-by":"crossref","DOI":"10.1073\/pnas.2203480119","article-title":"Ovarian cancer cell fate regulation by the dynamics between saturated and unsaturated fatty acids","volume":"119","author":"Zhao","year":"2022","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.xfss.2025.01.005_bib53","article-title":"Aramchol downregulates stearoyl CoA-desaturase 1 in hepatic stellate cells to attenuate cellular fibrogenesis","volume":"3","author":"Bhattacharya","year":"2021","journal-title":"JHEP Rep"},{"key":"10.1016\/j.xfss.2025.01.005_bib54","doi-asserted-by":"crossref","first-page":"1001","DOI":"10.1016\/j.molcel.2018.11.028","article-title":"Lipidomic analysis of \u03b1-synuclein neurotoxicity identifies stearoyl CoA desaturase as a target for Parkinson treatment","volume":"73","author":"Fanning","year":"2019","journal-title":"Mol Cell"},{"author":"Bogachkov","key":"10.1016\/j.xfss.2025.01.005_bib55"},{"key":"10.1016\/j.xfss.2025.01.005_bib56","doi-asserted-by":"crossref","first-page":"2171","DOI":"10.1007\/s12035-021-02695-1","article-title":"Non-clinical pharmacology of YTX-7739: a clinical stage stearoyl-CoA desaturase inhibitor being developed for Parkinson's disease","volume":"59","author":"Tardiff","year":"2022","journal-title":"Mol Neurobiol"}],"container-title":["F&S Science"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2666335X2500014X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2666335X2500014X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,5,15]],"date-time":"2025-05-15T05:29:14Z","timestamp":1747286954000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2666335X2500014X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,5]]},"references-count":56,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2025,5]]}},"alternative-id":["S2666335X2500014X"],"URL":"https:\/\/doi.org\/10.1016\/j.xfss.2025.01.005","relation":{},"ISSN":["2666-335X"],"issn-type":[{"type":"print","value":"2666-335X"}],"subject":[],"published":{"date-parts":[[2025,5]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Stearoyl\u2013coenzyme A desaturase enhances cell survival in human uterine leiomyoma","name":"articletitle","label":"Article Title"},{"value":"F&S Science","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.xfss.2025.01.005","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 American Society for Reproductive Medicine. Published by Elsevier Inc. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}]}}