{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T03:33:00Z","timestamp":1793503980135,"version":"4.5.0"},"reference-count":39,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2021,5,1]],"date-time":"2021-05-01T00:00:00Z","timestamp":1619827200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,5,1]],"date-time":"2021-05-01T00:00:00Z","timestamp":1619827200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2021,4,28]],"date-time":"2021-04-28T00:00:00Z","timestamp":1619568000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100014175","name":"Shanghai Municipal Commission of Health and Family Planning","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100014175","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["cell.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["The Innovation"],"published-print":{"date-parts":[[2021,5]]},"DOI":"10.1016\/j.xinn.2021.100113","type":"journal-article","created":{"date-parts":[[2021,5,5]],"date-time":"2021-05-05T13:53:25Z","timestamp":1620222805000},"page":"100113","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":22,"title":["Impact of immunization programs on 11 childhood vaccine-preventable diseases in China: 1950\u20132018"],"prefix":"10.1016","volume":"2","author":[{"given":"Jinhua","family":"Pan","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yesheng","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lingsheng","family":"Cao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4757-1364","authenticated-orcid":false,"given":"Ying","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0140-3920","authenticated-orcid":false,"given":"Qi","family":"Zhao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shenglan","family":"Tang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8929-2008","authenticated-orcid":false,"given":"Wenfeng","family":"Gong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lei","family":"Guo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhixi","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zexuan","family":"Wen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bo","family":"Zheng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Weibing","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.xinn.2021.100113_bib1","doi-asserted-by":"crossref","first-page":"596","DOI":"10.1016\/S0264-410X(02)00623-0","article-title":"The global value of vaccination","volume":"21","author":"Ehreth","year":"2003","journal-title":"Vaccine"},{"key":"10.1016\/j.xinn.2021.100113_bib2","doi-asserted-by":"crossref","first-page":"2733","DOI":"10.1098\/rstb.2011.0076","article-title":"Vaccines and global health","volume":"366","author":"Greenwood","year":"2011","journal-title":"Philos. Trans. R. Soc. Lond. B Biol. Sci."},{"key":"10.1016\/j.xinn.2021.100113_bib3","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1038\/s41586-019-1656-7","article-title":"Immunization: vital progress, unfinished agenda","volume":"575","author":"Piot","year":"2019","journal-title":"Nature"},{"key":"10.1016\/j.xinn.2021.100113_bib4","doi-asserted-by":"crossref","first-page":"20140378","DOI":"10.1098\/rstb.2014.0378","article-title":"The prevention and eradication of smallpox: a commentary on Sloane (1755) 'An account of inoculation'","volume":"370","author":"Weiss","year":"2015","journal-title":"Philos. Trans. R. Soc. Lond. B Biol. Sci."},{"issue":"Suppl 1","key":"10.1016\/j.xinn.2021.100113_bib5","doi-asserted-by":"crossref","first-page":"S2","DOI":"10.1186\/1472-698X-9-S1-S2","article-title":"Global immunization: status, progress, challenges and future","volume":"9","author":"Duclos","year":"2009","journal-title":"BMC Int. Health Hum. Rights"},{"key":"10.1016\/j.xinn.2021.100113_bib6","doi-asserted-by":"crossref","first-page":"1213","DOI":"10.1093\/aje\/kwq320","article-title":"From emergence to eradication: the epidemiology of poliomyelitis deconstructed","volume":"172","author":"Nathanson","year":"2010","journal-title":"Am. J. Epidemiol."},{"key":"10.1016\/j.xinn.2021.100113_bib7","doi-asserted-by":"crossref","first-page":"940","DOI":"10.1016\/0264-410X(92)90329-I","article-title":"EPI for the 1990s. The Expanded Programme on Immunization Team","volume":"10","author":"Kim-Farley","year":"1992","journal-title":"Vaccine"},{"key":"10.1016\/j.xinn.2021.100113_bib8","first-page":"315","article-title":"How important are airfreight rates and vaccine packaging in cost-saving efforts for the Expanded Programme on Immunization?","volume":"75","author":"Schreuder","year":"1997","journal-title":"Bull. World Health Organ."},{"key":"10.1016\/j.xinn.2021.100113_bib10","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1186\/s12916-020-01699-3","article-title":"The burden of laboratory-confirmed pertussis in low- and middle-income countries since the inception of the Expanded Programme on Immunisation (EPI) in 1974: a systematic review and meta-analysis","volume":"18","author":"Muloiwa","year":"2020","journal-title":"BMC Med."},{"key":"10.1016\/j.xinn.2021.100113_bib11","series-title":"A 60-Year History of Disease Prevention and Control in China","author":"Wang","year":"2015"},{"key":"10.1016\/j.xinn.2021.100113_bib12","first-page":"359","article-title":"Achievements in prevention and control of seven infectious diseases targeted by the National Immunization Program in China across 70 years","volume":"25","author":"Wang","year":"2019","journal-title":"Chin. J. Vacc. Immun."},{"key":"10.1016\/j.xinn.2021.100113_bib13","doi-asserted-by":"crossref","first-page":"8131","DOI":"10.1016\/j.vaccine.2018.10.005","article-title":"Vaccine-preventable disease control in the People's Republic of China: 1949-2016","volume":"36","author":"Yu","year":"2018","journal-title":"Vaccine"},{"key":"10.1016\/j.xinn.2021.100113_bib14","doi-asserted-by":"crossref","first-page":"441","DOI":"10.1016\/j.jinf.2011.07.018","article-title":"Seroprevalence of antibodies to pertussis and diphtheria among healthy adults in China","volume":"63","author":"Zhang","year":"2011","journal-title":"J.\u00a0Infect."},{"key":"10.1016\/j.xinn.2021.100113_bib15","doi-asserted-by":"crossref","first-page":"1695","DOI":"10.3201\/eid1611.100401","article-title":"Effect of vaccination on Bordetella pertussis strains, China","volume":"16","author":"Zhang","year":"2010","journal-title":"Emerg. Infect. Dis."},{"key":"10.1016\/j.xinn.2021.100113_bib16","doi-asserted-by":"crossref","first-page":"e3015","DOI":"10.1371\/journal.pntd.0003015","article-title":"Vaccine strategies for the control and prevention of Japanese encephalitis in Mainland China, 1951-2011","volume":"8","author":"Gao","year":"2014","journal-title":"PLoS Negl. Trop. Dis."},{"key":"10.1016\/j.xinn.2021.100113_bib17","first-page":"437","article-title":"BCG in China","volume":"95","author":"Chen","year":"1982","journal-title":"Chin. Med. J. (Engl)"},{"key":"10.1016\/j.xinn.2021.100113_bib18","first-page":"443","article-title":"China's expanded program on immunization","volume":"105","author":"Wang","year":"1992","journal-title":"Chin. Med. J. (Engl)"},{"key":"10.1016\/j.xinn.2021.100113_bib19","first-page":"473","article-title":"China\u2019s expanded program on immunization: successes, challenges, and healthier children","volume":"19","author":"Lance","year":"2013","journal-title":"Chin. J. Vacc. Immun."},{"key":"10.1016\/j.xinn.2021.100113_bib20","series-title":"Vaccination Practice and Management","author":"Wang","year":"2006"},{"key":"10.1016\/j.xinn.2021.100113_bib21","series-title":"National Immunization Program","year":"2015"},{"key":"10.1016\/j.xinn.2021.100113_bib22","series-title":"Announcement on the Implementation of Expanded National Immunization Plan","year":"2008"},{"key":"10.1016\/j.xinn.2021.100113_bib23","series-title":"National Immunization Program for Children. Immunization Procedures and Instructions","year":"2016"},{"issue":"Suppl 1","key":"10.1016\/j.xinn.2021.100113_bib24","doi-asserted-by":"crossref","first-page":"A233","DOI":"10.1016\/j.vaccine.2014.12.017","article-title":"Thirty years of vaccination in Vietnam: impact and cost-effectiveness of the national expanded programme on immunization","volume":"33","author":"Jit","year":"2015","journal-title":"Vaccine"},{"key":"10.1016\/j.xinn.2021.100113_bib25","first-page":"382","article-title":"Burden of vaccine-preventable diseases-measles, tetanus, diphtheria and whooping cough-in Iran: findings from the GBD study 2010","volume":"19","author":"Mokhayeri","year":"2016","journal-title":"Arch. Iran. Med."},{"issue":"Suppl 9","key":"10.1016\/j.xinn.2021.100113_bib26","doi-asserted-by":"crossref","first-page":"J79","DOI":"10.1016\/j.vaccine.2013.05.054","article-title":"Review of hepatitis B surveillance in China: improving information to frame future directions in prevention and control","volume":"31","author":"Cui","year":"2013","journal-title":"Vaccine"},{"key":"10.1016\/j.xinn.2021.100113_bib27","doi-asserted-by":"crossref","first-page":"380","DOI":"10.1056\/NEJM199808063390606","article-title":"Gains in life expectancy from medical interventions--standardizing data on outcomes","volume":"339","author":"Wright","year":"1998","journal-title":"N.\u00a0Engl. J. Med."},{"key":"10.1016\/j.xinn.2021.100113_bib28","doi-asserted-by":"crossref","first-page":"716","DOI":"10.1016\/S1473-3099(17)30227-X","article-title":"Epidemiological features of and changes in incidence of infectious diseases in China in the first decade after the SARS outbreak: an observational trend study","volume":"17","author":"Yang","year":"2017","journal-title":"Lancet Infect. Dis."},{"key":"10.1016\/j.xinn.2021.100113_bib29","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1186\/s40249-021-00806-7","article-title":"Changes in newly notified cases and control of tuberculosis in China: time-series analysis of surveillance data","volume":"10","author":"Wang","year":"2021","journal-title":"Infect. Dis. Poverty"},{"key":"10.1016\/j.xinn.2021.100113_bib30","doi-asserted-by":"crossref","first-page":"20803","DOI":"10.7189\/jogh.10.020803","article-title":"Epidemiological characteristics and trends of notifiable infectious diseases in China from 1986 to 2016","volume":"10","author":"Jiang","year":"2020","journal-title":"J.\u00a0Glob. Health"},{"key":"10.1016\/j.xinn.2021.100113_bib31","series-title":"Global Burden of Disease Study 2019 (GBD 2019) Results","year":"2020"},{"key":"10.1016\/j.xinn.2021.100113_bib33","doi-asserted-by":"crossref","first-page":"5150","DOI":"10.1016\/j.vaccine.2018.07.019","volume":"36","author":"Danovaro-Holliday","year":"2018","journal-title":"Vaccine"},{"key":"10.1016\/j.xinn.2021.100113_bib34","doi-asserted-by":"crossref","first-page":"626","DOI":"10.2471\/BLT.14.020914","article-title":"China enters the global vaccine market","volume":"92","author":"Parry","year":"2014","journal-title":"Bull. World Health Organ."},{"key":"10.1016\/j.xinn.2021.100113_bib35","doi-asserted-by":"crossref","first-page":"c2004","DOI":"10.1136\/bmj.c2004","article-title":"Ten years of the global alliance for vaccines and immunisation","volume":"340","author":"Lee","year":"2010","journal-title":"BMJ"},{"key":"10.1016\/j.xinn.2021.100113_bib36","doi-asserted-by":"crossref","first-page":"502","DOI":"10.1186\/s12879-018-3422-0","article-title":"The landscape of vaccines in China: history, classification, supply, and price","volume":"18","author":"Zheng","year":"2018","journal-title":"BMC Infect. Dis."},{"issue":"Suppl 9","key":"10.1016\/j.xinn.2021.100113_bib37","doi-asserted-by":"crossref","first-page":"J15","DOI":"10.1016\/j.vaccine.2013.03.045","article-title":"The inception, achievements, and implications of the China GAVI Alliance project on hepatitis B immunization","volume":"31","author":"Kane","year":"2013","journal-title":"Vaccine"},{"key":"10.1016\/j.xinn.2021.100113_bib38","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1016\/j.epidem.2015.01.001","article-title":"Pneumococcal vaccination in older adults in the era of childhood vaccination: public health insights from a Norwegian statistical prediction study","volume":"11","author":"Steens","year":"2015","journal-title":"Epidemics"},{"key":"10.1016\/j.xinn.2021.100113_bib39","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1080\/21645515.2019.1661754","article-title":"Determinants of vaccination uptake, and influenza vaccine effectiveness in preventing deaths and hospital admissions in the elderly population; Treviso, Italy, 2014\/2015-2016\/2017 seasons","volume":"16","author":"Bellino","year":"2020","journal-title":"Hum. Vaccin. Immunother."},{"key":"10.1016\/j.xinn.2021.100113_bib40","first-page":"e210081","article-title":"Invasive pneumococcal diseases in children and adults before and after introduction of the 10-valent pneumococcal conjugate vaccine into the Austrian national immunization program","volume":"14","author":"Richter","year":"2019","journal-title":"PLoS One"},{"key":"10.1016\/j.xinn.2021.100113_bib41","doi-asserted-by":"crossref","first-page":"4","DOI":"10.1186\/1478-7954-1-4","article-title":"A generic model for the assessment of disease epidemiology: the computational basis of DisMod II","volume":"1","author":"Barendregt","year":"2003","journal-title":"Popul. Health Metr."}],"container-title":["The Innovation"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2666675821000382?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2666675821000382?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,13]],"date-time":"2025-11-13T03:48:43Z","timestamp":1763005723000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2666675821000382"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,5]]},"references-count":39,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2021,5]]}},"alternative-id":["S2666675821000382"],"URL":"https:\/\/doi.org\/10.1016\/j.xinn.2021.100113","relation":{"has-preprint":[{"id-type":"doi","id":"10.1101\/2020.07.01.20144246","asserted-by":"object"}]},"ISSN":["2666-6758"],"issn-type":[{"value":"2666-6758","type":"print"}],"subject":[],"published":{"date-parts":[[2021,5]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Impact of immunization programs on 11 childhood vaccine-preventable diseases in China: 1950\u20132018","name":"articletitle","label":"Article Title"},{"value":"The Innovation","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.xinn.2021.100113","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2021 The Authors.","name":"copyright","label":"Copyright"}],"article-number":"100113"}}