{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,8]],"date-time":"2026-10-08T00:49:26Z","timestamp":1791420566708,"version":"4.3.3"},"reference-count":46,"publisher":"Elsevier BV","issue":"6","license":[{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,9,4]],"date-time":"2026-09-04T00:00:00Z","timestamp":1788480000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100012659","name":"Foundation for Innovative Research Groups of the National Natural Science Foundation of China","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100012659","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","jidinnovations.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["JID Innovations"],"published-print":{"date-parts":[[2026,11]]},"DOI":"10.1016\/j.xjidi.2026.100535","type":"journal-article","created":{"date-parts":[[2026,9,9]],"date-time":"2026-09-09T23:23:41Z","timestamp":1788996221000},"page":"100535","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"title":["Hematological inflammatory markers as predictors of atherosclerotic progression in patients with psoriasis: A retrospective case\u2013control study from the SH-YIMED database"],"prefix":"10.1016","volume":"6","author":[{"given":"Miao","family":"Zhang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Munsoon","family":"Hong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ruiqing","family":"Cao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pengbo","family":"Gao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Seokgyeong","family":"Hong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ningyuan","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Liu","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiao","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guangyuan","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xin","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.xjidi.2026.100535_bib1","doi-asserted-by":"crossref","first-page":"505","DOI":"10.1016\/j.ccell.2023.02.001","article-title":"NETworking with cancer: the bidirectional interplay between cancer and neutrophil extracellular traps","volume":"41","author":"Adrover","year":"2023","journal-title":"Cancer Cell"},{"key":"10.1016\/j.xjidi.2026.100535_bib2","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1016\/j.abd.2019.05.002","article-title":"Evaluation of monocyte to high-density lipoprotein ratio, lymphocytes, monocytes, and platelets in psoriasis","volume":"95","author":"Akta\u015f Karabay","year":"2020","journal-title":"An Bras Dermatol"},{"key":"10.1016\/j.xjidi.2026.100535_bib3","doi-asserted-by":"crossref","first-page":"1101","DOI":"10.3390\/ph15091101","article-title":"Looking beyond the skin: pathophysiology of cardiovascular comorbidity in psoriasis and the protective role of biologics","volume":"15","author":"And\u00fajar","year":"2022","journal-title":"Pharmaceuticals (Basel)"},{"key":"10.1016\/j.xjidi.2026.100535_bib4","doi-asserted-by":"crossref","first-page":"976","DOI":"10.1016\/j.amjcard.2011.11.025","article-title":"Coronary artery disease in patients with psoriasis referred for coronary angiography","volume":"109","author":"Armstrong","year":"2012","journal-title":"Am J Cardiol"},{"key":"10.1016\/j.xjidi.2026.100535_bib5","doi-asserted-by":"crossref","first-page":"485","DOI":"10.1016\/S0002-9343(03)00074-3","article-title":"Potential cost-effectiveness of C-reactive protein screening followed by targeted statin therapy for the primary prevention of cardiovascular disease among patients without overt hyperlipidemia","volume":"114","author":"Blake","year":"2003","journal-title":"Am J Med"},{"key":"10.1016\/j.xjidi.2026.100535_bib6","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1016\/j.kint.2020.07.035","article-title":"A practical guide to multiple imputation of missing data in nephrology","volume":"99","author":"Blazek","year":"2021","journal-title":"Kidney Int"},{"key":"10.1016\/j.xjidi.2026.100535_bib7","doi-asserted-by":"crossref","first-page":"483","DOI":"10.7326\/0003-4819-151-7-200910060-00009","article-title":"C-reactive protein as a risk factor for coronary heart disease: a systematic review and meta-analyses for the U.S. Preventive Services Task Force","volume":"151","author":"Buckley","year":"2009","journal-title":"Ann Intern Med"},{"key":"10.1016\/j.xjidi.2026.100535_bib8","doi-asserted-by":"crossref","first-page":"137","DOI":"10.5350\/SEMB.20160216020543","article-title":"Evaluation of neutrophil-lymphocyte ratio and mean platelet volume in patients with psoriasis","volume":"50","author":"\u00c7erman","year":"2016","journal-title":"Med Bull Sisli Etfal Hosp"},{"key":"10.1016\/j.xjidi.2026.100535_bib9","first-page":"1000","article-title":"[Chinese guideline on the primary prevention of cardiovascular diseases]","volume":"48","year":"2020","journal-title":"Zhonghua Xin Xue Guan Bing Za Zhi"},{"key":"10.1016\/j.xjidi.2026.100535_bib10","first-page":"573","article-title":"\u4e2d\u56fd\u94f6\u5c51\u75c5\u8bca\u7597\u6307\u5357 Guideline for the diagnosis and treatment of psoriasis in China (2023\u7248).","volume":"56","year":"2023","journal-title":"Chin J Dermatol"},{"key":"10.1016\/j.xjidi.2026.100535_bib11","doi-asserted-by":"crossref","first-page":"1387","DOI":"10.1056\/NEJMoa032804","article-title":"C-reactive protein and other circulating markers of inflammation in the prediction of coronary heart disease","volume":"350","author":"Danesh","year":"2004","journal-title":"N Engl J Med"},{"key":"10.1016\/j.xjidi.2026.100535_bib12","doi-asserted-by":"crossref","DOI":"10.1111\/ijcp.14101","article-title":"The utility of systemic-immune inflammation index for predicting the disease activation in patients with psoriasis","volume":"75","author":"Dincer Rota","year":"2021","journal-title":"Int J Clin Pract"},{"key":"10.1016\/j.xjidi.2026.100535_bib13","doi-asserted-by":"crossref","first-page":"9553","DOI":"10.3390\/ijms23179553","article-title":"Investigation of the associations of novel inflammatory biomarkers-systemic inflammatory index (SII) and systemic inflammatory response index (SIRI)-with the severity of coronary artery disease and acute coronary syndrome occurrence","volume":"23","author":"Dziedzic","year":"2022","journal-title":"Int J Mol Sci"},{"key":"10.1016\/j.xjidi.2026.100535_bib14","doi-asserted-by":"crossref","first-page":"1670","DOI":"10.1016\/j.jacc.2021.02.009","article-title":"Cardiovascular risk in patients with psoriasis: JACC review topic of the week","volume":"77","author":"Garshick","year":"2021","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.xjidi.2026.100535_bib15","doi-asserted-by":"crossref","first-page":"503","DOI":"10.1016\/j.intimp.2018.10.002","article-title":"A novel systemic inflammation response index (SIRI) for predicting postoperative survival of patients with esophageal squamous cell carcinoma","volume":"65","author":"Geng","year":"2018","journal-title":"Int Immunopharmacol"},{"key":"10.1016\/j.xjidi.2026.100535_bib16","doi-asserted-by":"crossref","first-page":"1051","DOI":"10.2147\/CCID.S518521","article-title":"Association of the monocyte-to-high density lipoprotein ratio with the FRS and as a predictor of cardiovascular risk in individuals with psoriasis vulgaris","volume":"18","author":"Gu","year":"2025","journal-title":"Clin Cosmet Investig Dermatol"},{"key":"10.1016\/j.xjidi.2026.100535_bib17","doi-asserted-by":"crossref","DOI":"10.1111\/exd.15010","article-title":"Prospective evaluation of cardiovascular risk and mortality in patients with psoriasis: an American population-based study","volume":"33","author":"Kan","year":"2024","journal-title":"Exp Dermatol"},{"key":"10.1016\/j.xjidi.2026.100535_bib18","doi-asserted-by":"crossref","first-page":"230","DOI":"10.1186\/s12872-020-01500-6","article-title":"Preoperative neutrophil to lymphocyte ratio and platelet to lymphocyte ratio are associated with major adverse cardiovascular and cerebrovascular events in coronary heart disease patients undergoing non-cardiac surgery","volume":"20","author":"Larmann","year":"2020","journal-title":"BMC Cardiovasc Disord"},{"key":"10.1016\/j.xjidi.2026.100535_bib19","doi-asserted-by":"crossref","first-page":"3577","DOI":"10.1007\/s13555-026-01733-x","article-title":"The role of inflammatory biomarkers in disease severity and treatment response across psoriasis, atopic dermatitis, and hidradenitis suppurativa-a narrative review","volume":"16","author":"Lewandowska","year":"2026","journal-title":"Dermatol Ther (Heidelb)"},{"key":"10.1016\/j.xjidi.2026.100535_bib20","article-title":"The neutrophil-lymphocyte ratio is associated with all-cause and cardiovascular mortality in cardiovascular patients","volume":"14","author":"Li","year":"2024","journal-title":"Sci Rep"},{"key":"10.1016\/j.xjidi.2026.100535_bib21","doi-asserted-by":"crossref","first-page":"1969","DOI":"10.1111\/jdv.18296","article-title":"Global prevalence of metabolic syndrome in patients with psoriasis in the past two decades: current evidence","volume":"36","author":"Liu","year":"2022","journal-title":"J Eur Acad Dermatol Venereol"},{"key":"10.1016\/j.xjidi.2026.100535_bib22","first-page":"257","article-title":"Chemical biology of traditional Chinese medicine: a new paradigm driving target discovery and mechanism elucidation","volume":"11","author":"Lu","year":"2025","journal-title":"World J Integr Tradit West Med"},{"key":"10.1016\/j.xjidi.2026.100535_bib23","doi-asserted-by":"crossref","first-page":"345","DOI":"10.1080\/00325481.2022.2140535","article-title":"The systemic immune-inflammation index in predicting sepsis mortality","volume":"135","author":"Mangalesh","year":"2023","journal-title":"Postgrad Med"},{"key":"10.1016\/j.xjidi.2026.100535_bib24","doi-asserted-by":"crossref","first-page":"194","DOI":"10.1007\/s12016-020-08804-7","article-title":"A review of neutrophil extracellular traps (NETs) in disease: potential anti-nets therapeutics","volume":"61","author":"Mutua","year":"2021","journal-title":"Clin Rev Allergy Immunol"},{"key":"10.1016\/j.xjidi.2026.100535_bib25","first-page":"9516","article-title":"Neutrophil-to-lymphocyte and platelet-to-lymphocyte ratios as inflammatory markers in psoriasis: a case-control study","volume":"15","author":"Nguyen","year":"2023","journal-title":"Dermatol Rep"},{"key":"10.1016\/j.xjidi.2026.100535_bib26","doi-asserted-by":"crossref","DOI":"10.1111\/dth.13628","article-title":"High-sensitivity C-reactive protein as a biomarker in detecting subclinical atherosclerosis in psoriasis","volume":"33","author":"Niknezhad","year":"2020","journal-title":"Dermatol Ther"},{"key":"10.1016\/j.xjidi.2026.100535_bib27","doi-asserted-by":"crossref","DOI":"10.3389\/fendo.2022.1039700","article-title":"Predictive value of novel inflammatory markers platelet-to-lymphocyte ratio, neutrophil-to-lymphocyte ratio, and monocyte-to-lymphocyte ratio in arterial stiffness in patients with diabetes: a propensity score-matched analysis","volume":"13","author":"Ning","year":"2022","journal-title":"Front Endocrinol (Lausanne)"},{"key":"10.1016\/j.xjidi.2026.100535_bib28","doi-asserted-by":"crossref","first-page":"222","DOI":"10.1590\/abd1806-4841.20186397","article-title":"Metabolic syndrome, C-reactive protein and cardiovascular risk in psoriasis patients: a cross-sectional study [published correction appears in An Bras Dermatol 2018;93:628\u20139]","volume":"93","author":"Paschoal","year":"2018","journal-title":"An Bras Dermatol"},{"key":"10.1016\/j.xjidi.2026.100535_bib29","doi-asserted-by":"crossref","first-page":"499","DOI":"10.1161\/01.CIR.0000052939.59093.45","article-title":"Markers of inflammation and cardiovascular disease: application to clinical and public health practice: a statement for healthcare professionals from the Centers for Disease Control and Prevention and the American Heart Association","volume":"107","author":"Pearson","year":"2003","journal-title":"Circulation"},{"key":"10.1016\/j.xjidi.2026.100535_bib30","doi-asserted-by":"crossref","first-page":"2285","DOI":"10.1016\/j.immuni.2022.10.001","article-title":"Neutrophil \"plucking\" on megakaryocytes drives platelet production and boosts cardiovascular disease","volume":"55","author":"Petzold","year":"2022","journal-title":"Immunity"},{"key":"10.1016\/j.xjidi.2026.100535_bib31","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1007\/s00423-023-02786-8","article-title":"Prognostic role of platelet-to-lymphocyte ratio, neutrophil-to-lymphocyte, and lymphocyte-to-monocyte ratio in operated rectal cancer patients: systematic review and meta-analysis","volume":"408","author":"Portale","year":"2023","journal-title":"Langenbecks Arch Surg"},{"key":"10.1016\/j.xjidi.2026.100535_bib32","doi-asserted-by":"crossref","first-page":"2195","DOI":"10.1056\/NEJMoa0807646","article-title":"Rosuvastatin to prevent vascular events in men and women with elevated C-reactive protein","volume":"359","author":"Ridker","year":"2008","journal-title":"N Engl J Med"},{"key":"10.1016\/j.xjidi.2026.100535_bib33","doi-asserted-by":"crossref","first-page":"194","DOI":"10.1007\/s12016-012-8308-0","article-title":"Inflammation, atherosclerosis, and psoriasis [published correction appears in Clin Rev Allergy Immunol 2018;54:493]","volume":"44","author":"Siegel","year":"2013","journal-title":"Clin Rev Allergy Immunol"},{"key":"10.1016\/j.xjidi.2026.100535_bib34","doi-asserted-by":"crossref","first-page":"326","DOI":"10.14744\/SEMB.2023.47529","article-title":"Can the combination of magnetic resonance imaging, neutrophil-to-lymphocyte ratio and platelet-to-lymphocyte ratio predict the mass origin in ovarian masses?","volume":"57","author":"Talmac","year":"2023","journal-title":"Med Bull Sisli Etfal Hosp"},{"key":"10.1016\/j.xjidi.2026.100535_bib35","doi-asserted-by":"crossref","first-page":"322","DOI":"10.4103\/2229-5178.164483","article-title":"Role of C-reactive protein as a marker of disease severity and cardiovascular risk in patients with psoriasis","volume":"6","author":"Vadakayil","year":"2015","journal-title":"Indian Dermatol Online J"},{"key":"10.1016\/j.xjidi.2026.100535_bib36","doi-asserted-by":"crossref","first-page":"819","DOI":"10.1084\/jem.20112322","article-title":"Monocytes, neutrophils, and platelets cooperate to initiate and propagate venous thrombosis in mice in vivo","volume":"209","author":"von Br\u00fchl","year":"2012","journal-title":"J Exp Med"},{"key":"10.1016\/j.xjidi.2026.100535_bib37","doi-asserted-by":"crossref","DOI":"10.1016\/j.autrev.2024.103577","article-title":"Global prevalence of obesity in patients with psoriasis: an analysis in the past two decades","volume":"23","author":"Wang","year":"2024","journal-title":"Autoimmun Rev"},{"key":"10.1016\/j.xjidi.2026.100535_bib38","volume":"14","author":"Wang","year":"2023","journal-title":"Front Immunol"},{"key":"10.1016\/j.xjidi.2026.100535_bib39","doi-asserted-by":"crossref","first-page":"64","DOI":"10.1186\/s12865-021-00454-4","article-title":"Neutrophil to lymphocyte ratio, platelet to lymphocyte ratio, and other hematological parameters in psoriasis patients","volume":"22","author":"Wang","year":"2021","journal-title":"BMC Immunol"},{"key":"10.1016\/j.xjidi.2026.100535_bib40","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1186\/s12967-018-1638-9","article-title":"The systemic immune-inflammation index is an independent predictor of survival for metastatic colorectal cancer and its association with the lymphocytic response to the tumor","volume":"16","author":"Xie","year":"2018","journal-title":"J Transl Med"},{"key":"10.1016\/j.xjidi.2026.100535_bib41","article-title":"Association between systemic inflammation indicators and psoriasis: a cross-sectional study from NHANES [published correction appears in Front Immunol 2025;16:1690809]","volume":"16","author":"Xiong","year":"2025","journal-title":"Front Immunol"},{"key":"10.1016\/j.xjidi.2026.100535_bib42","doi-asserted-by":"crossref","DOI":"10.3389\/fcvm.2022.933913","article-title":"Systemic immune-inflammation index as a potential biomarker of cardiovascular diseases: a systematic review and meta-analysis","volume":"9","author":"Ye","year":"2022","journal-title":"Front Cardiovasc Med"},{"key":"10.1016\/j.xjidi.2026.100535_bib43","first-page":"352","article-title":"Systemic immune-inflammation index (SII) predicts increased severity in psoriasis and psoriatic arthritis","volume":"46","author":"Yorulmaz","year":"2020","journal-title":"Curr Health Sci J"},{"key":"10.1016\/j.xjidi.2026.100535_bib44","first-page":"443","article-title":"Epidemiology of hypertension in psoriasis: an analysis of trends from 2006 to 2023","volume":"15","author":"Zhang","year":"2025","journal-title":"Psoriasis (Auckl)"},{"key":"10.1016\/j.xjidi.2026.100535_bib45","doi-asserted-by":"crossref","DOI":"10.1016\/j.dsx.2024.103098","article-title":"Epidemiology of lipid disturbances in psoriasis: an analysis of trends from 2006 to 2023","volume":"18","author":"Zhang","year":"2024","journal-title":"Diabetes Metab Syndr"},{"key":"10.1016\/j.xjidi.2026.100535_bib46","article-title":"Bidirectional inflammatory mechanisms and hematological\/coagulation dysregulation in psoriasis complicated with atherosclerosis: a retrospective hospital-based case-control study leveraging the SH-YIMED clinical database","volume":"16","author":"Zhang","year":"2026","journal-title":"Psoriasis (Auckl)"}],"container-title":["JID Innovations"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2667026726000901?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2667026726000901?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T23:51:43Z","timestamp":1791417103000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2667026726000901"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,11]]},"references-count":46,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2026,11]]}},"alternative-id":["S2667026726000901"],"URL":"https:\/\/doi.org\/10.1016\/j.xjidi.2026.100535","relation":{},"ISSN":["2667-0267"],"issn-type":[{"value":"2667-0267","type":"print"}],"subject":[],"published":{"date-parts":[[2026,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Hematological inflammatory markers as predictors of atherosclerotic progression in patients with psoriasis: A retrospective case\u2013control study from the SH-YIMED database","name":"articletitle","label":"Article Title"},{"value":"JID Innovations","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.xjidi.2026.100535","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 The Author(s). Published by Elsevier Inc. on behalf of Society for Investigative Dermatology.","name":"copyright","label":"Copyright"}],"article-number":"100535"}}