{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,16]],"date-time":"2026-06-16T23:11:53Z","timestamp":1781651513236,"version":"3.54.5"},"reference-count":26,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2022,12,1]],"date-time":"2022-12-01T00:00:00Z","timestamp":1669852800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,12,1]],"date-time":"2022-12-01T00:00:00Z","timestamp":1669852800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2022,9,26]],"date-time":"2022-09-26T00:00:00Z","timestamp":1664150400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["jtcvsopen.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["JTCVS Open"],"published-print":{"date-parts":[[2022,12]]},"DOI":"10.1016\/j.xjon.2022.09.005","type":"journal-article","created":{"date-parts":[[2022,9,30]],"date-time":"2022-09-30T01:11:37Z","timestamp":1664500297000},"page":"364-371","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":8,"special_numbering":"C","title":["Cardiac surgery in children with trisomy 13 or trisomy 18: How safe is it?"],"prefix":"10.1016","volume":"12","author":[{"given":"Joshua M.","family":"Rosenblum","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kirk R.","family":"Kanter","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Subhadra","family":"Shashidharan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fawwaz R.","family":"Shaw","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paul J.","family":"Chai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.xjon.2022.09.005_bib1","doi-asserted-by":"crossref","first-page":"3062","DOI":"10.1002\/ajmg.a.37355","article-title":"Congenital anomalies associated with trisomy 18 or trisomy 13: a registry-based study in 16 European countries, 2000-2011","volume":"167A","author":"Springett","year":"2015","journal-title":"Am J Med Genet A"},{"key":"10.1016\/j.xjon.2022.09.005_bib2","doi-asserted-by":"crossref","first-page":"e20170772","DOI":"10.1542\/peds.2017-0772","article-title":"Congenital heart surgery on in-hospital mortality in trisomy 13 and 18","volume":"140","author":"Kosiv","year":"2017","journal-title":"Pediatrics"},{"key":"10.1016\/j.xjon.2022.09.005_bib3","doi-asserted-by":"crossref","first-page":"2382","DOI":"10.1002\/ajmg.a.61365","article-title":"Trisomy 13 and 18-Prevalence and mortality-A multi-registry population based analysis","volume":"179","author":"Goel","year":"2019","journal-title":"Am J Med Genet A"},{"key":"10.1016\/j.xjon.2022.09.005_bib4","doi-asserted-by":"crossref","first-page":"825","DOI":"10.1002\/ajmg.a.37495","article-title":"Survival of children with trisomy 13 and trisomy 18: a multi-state population-based study","volume":"170A","author":"Meyer","year":"2016","journal-title":"Am J Med Genet A"},{"key":"10.1016\/j.xjon.2022.09.005_bib5","doi-asserted-by":"crossref","first-page":"420","DOI":"10.1001\/jama.2016.9819","article-title":"Survival and surgical interventions for children with trisomy 13 and 18","volume":"316","author":"Nelson","year":"2016","journal-title":"JAMA"},{"key":"10.1016\/j.xjon.2022.09.005_bib6","doi-asserted-by":"crossref","first-page":"777","DOI":"10.1542\/peds.111.4.777","article-title":"Population-based analyses of mortality in trisomy 13 and trisomy 18","volume":"111","author":"Rasmussen","year":"2003","journal-title":"Pediatrics"},{"key":"10.1016\/j.xjon.2022.09.005_bib7","doi-asserted-by":"crossref","first-page":"1949","DOI":"10.1016\/j.athoracsur.2017.03.039","article-title":"Invited commentary","volume":"103","author":"Graham","year":"2017","journal-title":"Ann Thorac Surg"},{"key":"10.1016\/j.xjon.2022.09.005_bib8","doi-asserted-by":"crossref","first-page":"1278","DOI":"10.1016\/j.athoracsur.2019.06.001","article-title":"Trisomy 13, large ventricular septal defect with failure to thrive: family wishes to have complete repair","volume":"108","author":"Harahsheh","year":"2019","journal-title":"Ann Thorac Surg"},{"key":"10.1016\/j.xjon.2022.09.005_bib9","doi-asserted-by":"crossref","first-page":"e20172809","DOI":"10.1542\/peds.2017-2809","article-title":"Trisomy 13 and 18: cardiac surgery makes sense if it is part of a comprehensive care strategy","volume":"140","author":"Jenkins","year":"2017","journal-title":"Pediatrics"},{"key":"10.1016\/j.xjon.2022.09.005_bib10","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1016\/j.jtcvs.2020.09.027","article-title":"Commentary: cardiac surgery in children with trisomy 13 and trisomy 18: \u201cIs it the quality of life or the quantity?\u201d","volume":"162","author":"Kavarana","year":"2021","journal-title":"J Thorac Cardiovasc Surg"},{"key":"10.1016\/j.xjon.2022.09.005_bib11","doi-asserted-by":"crossref","first-page":"396","DOI":"10.1001\/jama.2016.9470","article-title":"Trisomy 13 and 18\u2013treatment decisions in a stable gray zone","volume":"316","author":"Lantos","year":"2016","journal-title":"JAMA"},{"key":"10.1016\/j.xjon.2022.09.005_bib12","doi-asserted-by":"crossref","first-page":"250","DOI":"10.1016\/j.jtcvs.2020.09.052","article-title":"Commentary: trisomies and tribulations: don't get blindsided by pulmonary complications after pediatric heart surgery","volume":"162","author":"Overbey","year":"2021","journal-title":"J Thorac Cardiovasc Surg"},{"key":"10.1016\/j.xjon.2022.09.005_bib13","doi-asserted-by":"crossref","first-page":"801","DOI":"10.1016\/j.amjcard.2003.12.012","article-title":"Effectiveness of cardiac surgery in trisomies 13 and 18 (from the pediatric cardiac care consortium)","volume":"93","author":"Graham","year":"2004","journal-title":"Am J Cardiol"},{"key":"10.1016\/j.xjon.2022.09.005_bib14","doi-asserted-by":"crossref","first-page":"2626","DOI":"10.1002\/ajmg.a.34284","article-title":"Natural outcome of trisomy 13, trisomy 18, and triploidy after prenatal diagnosis","volume":"155A","author":"Lakovschek","year":"2011","journal-title":"Am J Med Genet A"},{"key":"10.1016\/j.xjon.2022.09.005_bib15","doi-asserted-by":"crossref","first-page":"987","DOI":"10.1007\/s00246-015-1109-5","article-title":"A contemporary, single-institutional experience of surgical versus expectant management of congenital heart disease in trisomy 13 and 18 patients","volume":"36","author":"Costello","year":"2015","journal-title":"Pediatr Cardiol"},{"key":"10.1016\/j.xjon.2022.09.005_bib16","doi-asserted-by":"crossref","first-page":"550","DOI":"10.1177\/2150135118782145","article-title":"Trisomy 18 and congenital heart disease: single-center review of outcomes and parental perspectives","volume":"9","author":"Davisson","year":"2018","journal-title":"World J Pediatr Congenit Heart Surg"},{"key":"10.1016\/j.xjon.2022.09.005_bib17","doi-asserted-by":"crossref","first-page":"140","DOI":"10.1007\/s00246-017-1738-y","article-title":"Factors influencing outcomes after cardiac intervention in infants with trisomy 13 and 18","volume":"39","author":"Peterson","year":"2018","journal-title":"Pediatr Cardiol"},{"key":"10.1016\/j.xjon.2022.09.005_bib18","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1016\/j.jtcvs.2020.08.082","article-title":"Impact of trisomy 13 and 18 on airway anomalies and pulmonary complications after cardiac surgery","volume":"162","author":"Swanson","year":"2021","journal-title":"J Thorac Cardiovasc Surg"},{"key":"10.1016\/j.xjon.2022.09.005_bib19","doi-asserted-by":"crossref","first-page":"e012349","DOI":"10.1161\/JAHA.119.012349","article-title":"Cardiac\u00a0surgery in patients with trisomy 13 and 18: an analysis of the Society of Thoracic Surgeons congenital heart surgery database","volume":"8","author":"Cooper","year":"2019","journal-title":"J Am Heart Assoc"},{"key":"10.1016\/j.xjon.2022.09.005_bib20","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1007\/s00246-018-2001-x","article-title":"Mortality and resource use following cardiac interventions in children with trisomy 13 and trisomy 18 and congenital heart disease","volume":"40","author":"Domingo","year":"2019","journal-title":"Pediatr Cardiol"},{"key":"10.1016\/j.xjon.2022.09.005_bib21","doi-asserted-by":"crossref","first-page":"806","DOI":"10.1002\/ajmg.a.62044","article-title":"A validated model for prediction of survival to 6 months in patients with trisomy 13 and 18","volume":"185","author":"Kosiv","year":"2021","journal-title":"Am J Med Genet A"},{"key":"10.1016\/j.xjon.2022.09.005_bib22","doi-asserted-by":"crossref","first-page":"595","DOI":"10.1007\/s00246-018-2032-3","article-title":"Congenital heart surgical admissions in patients with trisomy 13 and 18: frequency, morbidity, and mortality","volume":"40","author":"Ma","year":"2019","journal-title":"Pediatr Cardiol"},{"key":"10.1016\/j.xjon.2022.09.005_bib23","doi-asserted-by":"crossref","first-page":"2641","DOI":"10.1002\/ajmg.a.34285","article-title":"The impact of cardiac surgery in patients with trisomy 18 and trisomy 13 in Japan","volume":"155A","author":"Maeda","year":"2011","journal-title":"Am J Med Genet A"},{"key":"10.1016\/j.xjon.2022.09.005_bib24","doi-asserted-by":"crossref","first-page":"869","DOI":"10.1542\/peds.2011-2139","article-title":"Inpatient hospital care of children with trisomy 13 and trisomy 18 in the United States","volume":"129","author":"Nelson","year":"2012","journal-title":"Pediatrics"},{"key":"10.1016\/j.xjon.2022.09.005_bib25","doi-asserted-by":"crossref","first-page":"1941","DOI":"10.1016\/j.athoracsur.2017.02.068","article-title":"Long-term outcomes of children with trisomy 13 and 18 after congenital heart disease interventions","volume":"103","author":"Peterson","year":"2017","journal-title":"Ann Thorac Surg"},{"key":"10.1016\/j.xjon.2022.09.005_bib26","doi-asserted-by":"crossref","first-page":"1319","DOI":"10.1007\/s00246-020-02444-6","article-title":"Cardiac surgery in trisomy 13 and 18: a guide to clinical decision-making","volume":"41","author":"Carvajal","year":"2020","journal-title":"Pediatr Cardiol"}],"container-title":["JTCVS Open"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2666273622003564?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2666273622003564?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,12]],"date-time":"2025-11-12T20:47:31Z","timestamp":1762980451000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2666273622003564"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,12]]},"references-count":26,"alternative-id":["S2666273622003564"],"URL":"https:\/\/doi.org\/10.1016\/j.xjon.2022.09.005","relation":{},"ISSN":["2666-2736"],"issn-type":[{"value":"2666-2736","type":"print"}],"subject":[],"published":{"date-parts":[[2022,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Cardiac surgery in children with trisomy 13 or trisomy 18: How safe is it?","name":"articletitle","label":"Article Title"},{"value":"JTCVS Open","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.xjon.2022.09.005","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2022 The Author(s). Published by Elsevier Inc. on behalf of The American Association for Thoracic Surgery.","name":"copyright","label":"Copyright"}]}}