{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,13]],"date-time":"2026-02-13T04:28:09Z","timestamp":1770956889297,"version":"3.50.1"},"reference-count":23,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2023,12,1]],"date-time":"2023-12-01T00:00:00Z","timestamp":1701388800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,12,1]],"date-time":"2023-12-01T00:00:00Z","timestamp":1701388800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2023,8,31]],"date-time":"2023-08-31T00:00:00Z","timestamp":1693440000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100005348","name":"American Association for Thoracic Surgery","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100005348","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["jtcvsopen.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["JTCVS Open"],"published-print":{"date-parts":[[2023,12]]},"DOI":"10.1016\/j.xjon.2023.08.015","type":"journal-article","created":{"date-parts":[[2023,9,4]],"date-time":"2023-09-04T19:31:51Z","timestamp":1693855911000},"page":"38-47","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":8,"special_numbering":"C","title":["Biomechanical properties of the aortic root are distinct from those of the ascending aorta in both normal and aneurysmal states"],"prefix":"10.1016","volume":"16","author":[{"given":"Jennifer C.-Y.","family":"Chung","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daniella","family":"Eliathamby","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hijun","family":"Seo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chun-Po","family":"Fan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rifat","family":"Islam","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Karamvir","family":"Deol","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Craig A.","family":"Simmons","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maral","family":"Ouzounian","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.xjon.2023.08.015_bib1","first-page":"40","article-title":"Hemodynamics of the aortic valve and root: implications for surgery","volume":"2","author":"De Paulis","year":"2013","journal-title":"Ann Cardiothorac Surg"},{"key":"10.1016\/j.xjon.2023.08.015_bib2","doi-asserted-by":"crossref","first-page":"1175","DOI":"10.1016\/S0895-7061(97)00311-7","article-title":"Vascular compliance and cardiovascular disease: a risk factor or a marker?","volume":"10","author":"Glasser","year":"1997","journal-title":"Am J Hypertens"},{"key":"10.1016\/j.xjon.2023.08.015_bib3","doi-asserted-by":"crossref","first-page":"e334","DOI":"10.1161\/CIR.0000000000001106","article-title":"2022 ACC\/AHA guideline for the diagnosis and management of aortic disease: a report of the American Heart Association\/American College of Cardiology Joint Committee on clinical practice guidelines","volume":"146","author":"Isselbacher","year":"2022","journal-title":"Circulation"},{"key":"10.1016\/j.xjon.2023.08.015_bib4","doi-asserted-by":"crossref","first-page":"2873","DOI":"10.1093\/eurheartj\/ehu281","volume":"35","author":"Erbel","year":"2014","journal-title":"Eur Heart J"},{"key":"10.1016\/j.xjon.2023.08.015_bib5","doi-asserted-by":"crossref","first-page":"460","DOI":"10.1016\/j.jtcvs.2011.07.058","article-title":"Effect of aneurysm on the mechanical dissection properties of the human ascending thoracic aorta","volume":"143","author":"Pasta","year":"2012","journal-title":"J Thorac Cardiovasc Surg"},{"key":"10.1016\/j.xjon.2023.08.015_bib6","doi-asserted-by":"crossref","first-page":"1082","DOI":"10.1016\/j.jtcvs.2014.06.021","article-title":"Energy\u00a0loss, a novel biomechanical parameter, correlates with aortic aneurysm size and histopathologic findings","volume":"148","author":"Chung","year":"2014","journal-title":"J Thorac Cardiovasc Surg"},{"key":"10.1016\/j.xjon.2023.08.015_bib7","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1016\/j.jtcvs.2008.07.023","article-title":"Ascending thoracic aortic aneurysms are associated with compositional remodeling and vessel stiffening but not weakening in age-matched subjects","volume":"137","author":"Iliopoulos","year":"2009","journal-title":"J Thorac Cardiovasc Surg"},{"key":"10.1016\/j.xjon.2023.08.015_bib8","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.xjon.2021.12.001","article-title":"Biomechanics in ascending aortic aneurysms correlate with tissue composition and strength","volume":"9","author":"Nightingale","year":"2022","journal-title":"JTCVS Open"},{"key":"10.1016\/j.xjon.2023.08.015_bib9","doi-asserted-by":"crossref","first-page":"e016715","DOI":"10.1161\/JAHA.120.016715","article-title":"Biomechanics of aortic dissection: a comparison of aortas associated with bicuspid and tricuspid aortic valves","volume":"9","author":"Chung","year":"2020","journal-title":"J Am Heart Assoc"},{"key":"10.1016\/j.xjon.2023.08.015_bib10","doi-asserted-by":"crossref","first-page":"624","DOI":"10.1114\/1.1484220","article-title":"Mechanical properties of dilated human ascending aorta","volume":"30","author":"Okamoto","year":"2002","journal-title":"Ann Biomed Eng"},{"key":"10.1016\/j.xjon.2023.08.015_bib11","doi-asserted-by":"crossref","first-page":"700","DOI":"10.1016\/j.ejvs.2010.02.015","article-title":"In\u00a0vitro characterisation of physiological and maximum elastic modulus of ascending thoracic aortic aneurysms using uniaxial tensile testing","volume":"39","author":"Duprey","year":"2010","journal-title":"Eur J Vasc Endovasc Surg"},{"key":"10.1016\/j.xjon.2023.08.015_bib12","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1016\/j.carpath.2016.11.001","article-title":"Loss of mechanical directional dependency of the ascending aorta with severe medial degeneration","volume":"26","author":"Chung","year":"2017","journal-title":"Cardiovasc Pathol"},{"key":"10.1016\/j.xjon.2023.08.015_bib13","doi-asserted-by":"crossref","first-page":"367","DOI":"10.1093\/ejcts\/ezab471","article-title":"Ascending aortic aneurysm haemodynamics are associated with aortic wall biomechanical properties","volume":"61","author":"McClarty","year":"2022","journal-title":"Eur J Cardiothorac Surg"},{"key":"10.1016\/j.xjon.2023.08.015_bib14","doi-asserted-by":"crossref","DOI":"10.3389\/fbioe.2021.750656","article-title":"High wall shear stress can predict wall degradation in ascending aortic aneurysms: an integrated biomechanics study","volume":"9","author":"Salmasi","year":"2021","journal-title":"Front Bioeng Biotechnol"},{"key":"10.1016\/j.xjon.2023.08.015_bib15","article-title":"Magnetic resonance imaging-based hemodynamic wall shear stress alters aortic wall tissue biomechanics in bicuspid aortic valve patients","author":"Nightingale","year":"2023","journal-title":"J Thorac Cardiovasc Surg"},{"key":"10.1016\/j.xjon.2023.08.015_bib16","doi-asserted-by":"crossref","first-page":"156","DOI":"10.1016\/j.jbiomech.2018.04.037","article-title":"Biomechanical characterization of the native porcine aortic root","volume":"74","author":"Bechsgaard","year":"2018","journal-title":"J Biomech"},{"key":"10.1016\/j.xjon.2023.08.015_bib17","doi-asserted-by":"crossref","DOI":"10.1016\/j.jbiomech.2020.110009","article-title":"The importance of collagen composition and biomechanics for the porcine aortic root","volume":"111","author":"Salvig","year":"2020","journal-title":"J Biomech"},{"key":"10.1016\/j.xjon.2023.08.015_bib18","doi-asserted-by":"crossref","first-page":"1367","DOI":"10.1016\/j.athoracsur.2021.07.042","article-title":"Patient-specific biomechanics in Marfan ascending thoracic aortic aneurysms","volume":"114","author":"Xuan","year":"2022","journal-title":"Ann Thorac Surg"},{"key":"10.1016\/j.xjon.2023.08.015_bib19","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1016\/j.athoracsur.2011.08.002","article-title":"Comparison of mechanical properties of human ascending aorta and aortic sinuses","volume":"93","author":"Azadani","year":"2012","journal-title":"Ann Thorac Surg"},{"key":"10.1016\/j.xjon.2023.08.015_bib20","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1016\/j.ejcts.2010.08.056","article-title":"Significant differences in the material properties between aged human and porcine aortic tissues","volume":"40","author":"Martin","year":"2011","journal-title":"Eur J Cardiothorac Surg"},{"key":"10.1016\/j.xjon.2023.08.015_bib21","doi-asserted-by":"crossref","DOI":"10.1016\/j.jmbbm.2021.104705","article-title":"Regional biomechanical and failure properties of healthy human ascending aorta and root","volume":"123","author":"Xuan","year":"2021","journal-title":"J Mech Behav Biomed Mater"},{"key":"10.1016\/j.xjon.2023.08.015_bib22","doi-asserted-by":"crossref","first-page":"931","DOI":"10.1016\/j.jbiomech.2012.12.004","article-title":"Biomechanical properties and histological structure of sinus of valsalva aneurysms in relation to age and region","volume":"46","author":"Iliopoulos","year":"2013","journal-title":"J Biomech"},{"key":"10.1016\/j.xjon.2023.08.015_bib23","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1016\/j.athoracsur.2014.03.016","article-title":"Effects of aneurysm on the mechanical properties and histologic structure of aortic sinuses","volume":"98","author":"Kritharis","year":"2014","journal-title":"Ann Thorac Surg"}],"container-title":["JTCVS Open"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2666273623002309?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2666273623002309?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,12]],"date-time":"2025-11-12T20:53:27Z","timestamp":1762980807000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2666273623002309"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,12]]},"references-count":23,"alternative-id":["S2666273623002309"],"URL":"https:\/\/doi.org\/10.1016\/j.xjon.2023.08.015","relation":{},"ISSN":["2666-2736"],"issn-type":[{"value":"2666-2736","type":"print"}],"subject":[],"published":{"date-parts":[[2023,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Biomechanical properties of the aortic root are distinct from those of the ascending aorta in both normal and aneurysmal states","name":"articletitle","label":"Article Title"},{"value":"JTCVS Open","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.xjon.2023.08.015","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2023 The Author(s). Published by Elsevier Inc. on behalf of The American Association for Thoracic Surgery.","name":"copyright","label":"Copyright"}]}}