{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,9]],"date-time":"2026-07-09T10:29:03Z","timestamp":1783592943524,"version":"3.55.0"},"reference-count":39,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,4,7]],"date-time":"2026-04-07T00:00:00Z","timestamp":1775520000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100007109","name":"May and Samuel Rudin Family Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100007109","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.jp","jtcvsopen.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["JTCVS Open"],"published-print":{"date-parts":[[2026,6]]},"DOI":"10.1016\/j.xjon.2026.101808","type":"journal-article","created":{"date-parts":[[2026,4,10]],"date-time":"2026-04-10T17:43:41Z","timestamp":1775843021000},"page":"101808","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"C","title":["Hypoxemia after thoracic aortic aneurysm repair"],"prefix":"10.1016","volume":"31","author":[{"ORCID":"https:\/\/orcid.org\/0009-0007-5614-7406","authenticated-orcid":false,"given":"Gift","family":"Owolabi","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuichiro","family":"Kitada","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jack","family":"Nickles","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yanling","family":"Zhao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paul","family":"Kurlansky","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lauren","family":"Sutherland","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jonathan","family":"Hastie","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas","family":"O'Donnell","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Virendra","family":"Patel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adham","family":"Elmously","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hiroo","family":"Takayama","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"2","key":"10.1016\/j.xjon.2026.101808_bib1","first-page":"251","article-title":"Risk factors for hypoxemia following surgical repair of acute type A aortic dissection","volume":"24","author":"Liu","year":"2017","journal-title":"Interact Cardiovasc Thorac Surg"},{"issue":"4","key":"10.1016\/j.xjon.2026.101808_bib2","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0093992","article-title":"Postoperative hypoxia and length of intensive care unit stay after cardiac surgery: the underweight paradox?","volume":"9","author":"Ranucci","year":"2014","journal-title":"PLoS One"},{"issue":"1","key":"10.1016\/j.xjon.2026.101808_bib3","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1186\/s13019-024-02775-y","article-title":"Study on risk factors and treatment strategies of hypoxemia after acute type a aortic dissection surgery","volume":"19","author":"Yu","year":"2024","journal-title":"J Cardiothorac Surg"},{"issue":"2","key":"10.1016\/j.xjon.2026.101808_bib4","doi-asserted-by":"crossref","first-page":"555","DOI":"10.1213\/ANE.0000000000004553","article-title":"Hypoxemia within the first three postoperative days is associated with increased one-year postoperative mortality after adjusting for perioperative opioids and other confounders","volume":"131","author":"Bartels","year":"2020","journal-title":"Anesth Analg"},{"issue":"5","key":"10.1016\/j.xjon.2026.101808_bib5","doi-asserted-by":"crossref","first-page":"506","DOI":"10.1053\/jcan.2000.9488","article-title":"Postcardiopulmonary bypass hypoxemia: a prospective study on incidence, risk factors, and clinical significance","volume":"14","author":"Weiss","year":"2000","journal-title":"J Cardiothorac Vasc Anesth"},{"issue":"6","key":"10.1016\/j.xjon.2026.101808_bib6","first-page":"355","article-title":"Hypoxemia after heart surgery. An exception or a normal development?","volume":"58","author":"Rapati","year":"1992","journal-title":"Minerva Anestesiol"},{"issue":"11","key":"10.1016\/j.xjon.2026.101808_bib7","doi-asserted-by":"crossref","first-page":"1578","DOI":"10.7150\/ijms.6904","article-title":"Risk factors for pulmonary complications following cardiac surgery with cardiopulmonary bypass","volume":"10","author":"Ji","year":"2013","journal-title":"Int J Med Sci"},{"issue":"1","key":"10.1016\/j.xjon.2026.101808_bib8","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1111\/j.1540-8191.2009.00823.x","article-title":"Lung dysfunction following cardiopulmonary bypass","volume":"25","author":"Apostolakis","year":"2010","journal-title":"J Card Surg"},{"issue":"2","key":"10.1016\/j.xjon.2026.101808_bib9","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1016\/j.bpa.2015.04.002","article-title":"Pulmonary complications of cardiopulmonary bypass","volume":"29","author":"Huffmyer","year":"2015","journal-title":"Best Pract Res Clin Anaesthesiol"},{"issue":"50","key":"10.1016\/j.xjon.2026.101808_bib10","doi-asserted-by":"crossref","DOI":"10.1097\/MD.0000000000032337","article-title":"Risk factors and long-term prognosis for postoperative hypoxemia in patients with acute type A aortic dissection: a retrospective observational study","volume":"101","author":"Song","year":"2022","journal-title":"Medicine (Baltimore)"},{"issue":"7","key":"10.1016\/j.xjon.2026.101808_bib11","doi-asserted-by":"crossref","first-page":"7388","DOI":"10.21037\/apm-21-1428","article-title":"Independent risk factors of hypoxemia in patients after surgery with acute type A aortic dissection","volume":"10","author":"Zhou","year":"2021","journal-title":"Ann Palliat Med"},{"issue":"1","key":"10.1016\/j.xjon.2026.101808_bib12","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1186\/s13019-019-0888-9","article-title":"Increased risk for the development of postoperative severe hypoxemia in obese women with acute type a aortic dissection","volume":"14","author":"Gong","year":"2019","journal-title":"J Cardiothorac Surg"},{"issue":"1","key":"10.1016\/j.xjon.2026.101808_bib13","doi-asserted-by":"crossref","first-page":"118","DOI":"10.1186\/1749-8090-8-118","article-title":"Risk factors for postoperative hypoxemia in patients undergoing Stanford A aortic dissection surgery","volume":"8","author":"Wang","year":"2013","journal-title":"J Cardiothorac Surg"},{"issue":"6","key":"10.1016\/j.xjon.2026.101808_bib14","doi-asserted-by":"crossref","first-page":"1248","DOI":"10.1016\/S0022-5223(96)70228-3","article-title":"Effects of cardiopulmonary bypass and circulatory arrest on endothelium-dependent vasodilation in the lung","volume":"111","author":"Kirshbom","year":"1996","journal-title":"J Thorac Cardiovasc Surg"},{"issue":"1","key":"10.1016\/j.xjon.2026.101808_bib15","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1016\/j.jcrc.2015.10.021","article-title":"Prolonged postoperative respiratory support after proximal thoracic aortic surgery: is deep hypothermic circulatory arrest a risk factor?","volume":"31","author":"Schechter","year":"2016","journal-title":"J Crit Care"},{"issue":"21","key":"10.1016\/j.xjon.2026.101808_bib16","doi-asserted-by":"crossref","DOI":"10.1097\/MD.0000000000042529","article-title":"Analysis of the effect of mild hypothermic circulatory arrest anesthesia on postoperative lung function in patients with aortic dissection","volume":"104","author":"Zhou","year":"2025","journal-title":"Medicine (Baltimore)"},{"issue":"1","key":"10.1016\/j.xjon.2026.101808_bib17","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1164\/rccm.202303-0558WS","article-title":"A new global definition of acute respiratory distress syndrome","volume":"209","author":"Matthay","year":"2024","journal-title":"Am J Respir Crit Care Med"},{"issue":"4","key":"10.1016\/j.xjon.2026.101808_bib18","doi-asserted-by":"crossref","first-page":"669","DOI":"10.1016\/j.athoracsur.2023.12.006","article-title":"Perioperative care in cardiac surgery: a joint consensus statement by the Enhanced Recovery After Surgery (ERAS) Cardiac Society, ERAS International Society, and the Society of Thoracic Surgeons (STS)","volume":"117","author":"Grant","year":"2024","journal-title":"Ann Thorac Surg"},{"issue":"8","key":"10.1016\/j.xjon.2026.101808_bib19","doi-asserted-by":"crossref","first-page":"680","DOI":"10.1007\/s00595-006-3226-5","article-title":"Risk factors for hypoxemia after surgery for acute type A aortic dissection","volume":"36","author":"Nakajima","year":"2006","journal-title":"Surg Today"},{"issue":"8","key":"10.1016\/j.xjon.2026.101808_bib20","doi-asserted-by":"crossref","first-page":"940","DOI":"10.15537\/smj.2015.8.11583","article-title":"Independent risk factors for hypoxemia after surgery for acute aortic dissection","volume":"36","author":"Sheng","year":"2015","journal-title":"Saudi Med J"},{"issue":"5","key":"10.1016\/j.xjon.2026.101808_bib21","doi-asserted-by":"crossref","first-page":"940","DOI":"10.1016\/j.jcrc.2015.04.125","article-title":"Prolonged pulmonary support after cardiac surgery: incidence, risk factors and outcomes: a retrospective cohort study","volume":"30","author":"Bartz","year":"2015","journal-title":"J Crit Care"},{"issue":"11","key":"10.1016\/j.xjon.2026.101808_bib22","doi-asserted-by":"crossref","first-page":"1247","DOI":"10.2105\/AJPH.73.11.1247","article-title":"The national death index","volume":"73","author":"MacMahon","year":"1983","journal-title":"Am J Public Health"},{"key":"10.1016\/j.xjon.2026.101808_bib23","first-page":"14","article-title":"Central aortic versus axillary artery cannulation for aortic arch surgery","volume":"14","author":"Chung","year":"2023","journal-title":"J Thorac Cardiovasc Surg Open"},{"issue":"24","key":"10.1016\/j.xjon.2026.101808_bib24","doi-asserted-by":"crossref","first-page":"e223","DOI":"10.1016\/j.jacc.2022.08.004","article-title":"2022 ACC\/AHA guideline for the diagnosis and management of aortic disease","volume":"80","author":"Isselbacher","year":"2022","journal-title":"J Am Coll Cardiol"},{"issue":"3","key":"10.1016\/j.xjon.2026.101808_bib25","doi-asserted-by":"crossref","first-page":"658","DOI":"10.1093\/ejcts\/ezaa389","article-title":"Assessment of long-term outcomes: aortic valve reimplantation versus aortic valve and root replacement with biological valved conduit in aortic root aneurysm with tricuspid valve","volume":"59","author":"Yamabe","year":"2021","journal-title":"Eur J Cardiothorac Surg"},{"issue":"5","key":"10.1016\/j.xjon.2026.101808_bib26","doi-asserted-by":"crossref","first-page":"1529","DOI":"10.1016\/j.athoracsur.2021.05.044","article-title":"Valve-sparing root replacement versus bio-Bentall: inverse propensity weighting of 796 patients","volume":"113","author":"Bethancourt","year":"2022","journal-title":"Ann Thorac Surg"},{"issue":"4","key":"10.1016\/j.xjon.2026.101808_bib27","doi-asserted-by":"crossref","first-page":"933","DOI":"10.1053\/j.semtcvs.2021.02.004","article-title":"Bicuspid-associated aortic root aneurysm: mid to long-term outcomes of David V versus the bio-Bentall procedure","volume":"33","author":"Nguyen","year":"2021","journal-title":"Semin Thorac Cardiovasc Surg"},{"issue":"11","key":"10.1016\/j.xjon.2026.101808_bib28","doi-asserted-by":"crossref","first-page":"1344","DOI":"10.1111\/jocs.14241","article-title":"Double mattress suture lines for valve-sparing aortic root replacement","volume":"34","author":"Yamabe","year":"2019","journal-title":"J Card Surg"},{"key":"10.1016\/j.xjon.2026.101808_bib29","first-page":"39","article-title":"A novel dosing strategy of del Nido cardioplegia in aortic surgery","volume":"10","author":"Chung","year":"2022","journal-title":"J Thorac Cardiovasc Surg Open"},{"issue":"3","key":"10.1016\/j.xjon.2026.101808_bib30","doi-asserted-by":"crossref","first-page":"387","DOI":"10.1097\/EDE.0000000000000627","article-title":"Matching weights to simultaneously compare three treatment groups: comparison to three-way matching","volume":"28","author":"Yoshida","year":"2017","journal-title":"Epidemiology"},{"issue":"6","key":"10.1016\/j.xjon.2026.101808_bib31","doi-asserted-by":"crossref","first-page":"1384","DOI":"10.1016\/j.jtcvs.2016.12.055","article-title":"Pneumonia after cardiac surgery: experience of the National Institutes of Health\/Canadian Institutes of Health Research Cardiothoracic Surgical Trials Network","volume":"153","author":"Ailawadi","year":"2017","journal-title":"J Thorac Cardiovasc Surg"},{"issue":"6","key":"10.1016\/j.xjon.2026.101808_bib32","doi-asserted-by":"crossref","first-page":"2131","DOI":"10.1016\/j.jtcvs.2020.08.094","article-title":"Mortality due to hospital-acquired infection after cardiac surgery","volume":"163","author":"Massart","year":"2022","journal-title":"J Thorac Cardiovasc Surg"},{"issue":"1","key":"10.1016\/j.xjon.2026.101808_bib33","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1177\/0885066614523918","article-title":"Long-term mortality after pneumonia in cardiac surgery patients: a propensity-matched analysis","volume":"31","author":"Iba\u00f1ez","year":"2016","journal-title":"J Intensive Care Med"},{"issue":"5","key":"10.1016\/j.xjon.2026.101808_bib34","doi-asserted-by":"crossref","first-page":"597","DOI":"10.1164\/rccm.201501-0140OC","article-title":"Ten-year mortality after community-acquired pneumonia. A prospective cohort","volume":"192","author":"Eurich","year":"2015","journal-title":"Am J Respir Crit Care Med"},{"issue":"3","key":"10.1016\/j.xjon.2026.101808_bib35","doi-asserted-by":"crossref","first-page":"731","DOI":"10.1016\/S0003-4975(99)00096-X","article-title":"Effects of ischemia on pulmonary dysfunction after cardiopulmonary bypass","volume":"67","author":"Chai","year":"1999","journal-title":"Ann Thorac Surg"},{"issue":"14","key":"10.1016\/j.xjon.2026.101808_bib36","doi-asserted-by":"crossref","first-page":"3140","DOI":"10.12998\/wjcc.v11.i14.3140","article-title":"Postoperative hypoxemia for patients undergoing Stanford type A aortic dissection","volume":"11","author":"Liu","year":"2023","journal-title":"World J Clin Cases"},{"issue":"6","key":"10.1016\/j.xjon.2026.101808_bib37","doi-asserted-by":"crossref","first-page":"2267","DOI":"10.1016\/j.jtcvs.2018.01.085","article-title":"Oxygenation impairment after total arch replacement with a stented elephant trunk for type-A dissection","volume":"155","author":"Shen","year":"2018","journal-title":"J Thorac Cardiovasc Surg"},{"key":"10.1016\/j.xjon.2026.101808_bib38","doi-asserted-by":"crossref","first-page":"797","DOI":"10.2147\/VHRM.S544999","article-title":"Postoperative acute refractory hypoxemia after acute type A aortic dissection surgery: supporting the two-hit mechanism of transfusion-related acute lung injury. A retrospective cohort study","volume":"21","author":"Afolabi","year":"2025","journal-title":"Vasc Health Risk Manag"},{"issue":"33","key":"10.1016\/j.xjon.2026.101808_bib39","doi-asserted-by":"crossref","DOI":"10.1097\/MD.0000000000034704","article-title":"The risk factors of postoperative hypoxemia in patients with Stanford type A acute aortic dissection","volume":"102","author":"Wang","year":"2023","journal-title":"Medicine (Baltimore)"}],"container-title":["JTCVS Open"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2666273626002317?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2666273626002317?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,7,9]],"date-time":"2026-07-09T10:05:07Z","timestamp":1783591507000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2666273626002317"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,6]]},"references-count":39,"alternative-id":["S2666273626002317"],"URL":"https:\/\/doi.org\/10.1016\/j.xjon.2026.101808","relation":{},"ISSN":["2666-2736"],"issn-type":[{"value":"2666-2736","type":"print"}],"subject":[],"published":{"date-parts":[[2026,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Hypoxemia after thoracic aortic aneurysm repair","name":"articletitle","label":"Article Title"},{"value":"JTCVS Open","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.xjon.2026.101808","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 The Author(s). Published by Elsevier Inc. on behalf of The American Association for Thoracic Surgery.","name":"copyright","label":"Copyright"}],"article-number":"101808"}}