{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,13]],"date-time":"2026-11-13T01:31:11Z","timestamp":1794533471059,"version":"4.9.1"},"reference-count":24,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2025,3,1]],"date-time":"2025-03-01T00:00:00Z","timestamp":1740787200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,3,1]],"date-time":"2025-03-01T00:00:00Z","timestamp":1740787200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,12,24]],"date-time":"2024-12-24T00:00:00Z","timestamp":1734998400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000062","name":"NIDDK","doi-asserted-by":"publisher","award":["R01DK130266"],"award-info":[{"award-number":["R01DK130266"]}],"id":[{"id":"10.13039\/100000062","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["kidneymedicinejournal.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Kidney Medicine"],"published-print":{"date-parts":[[2025,3]]},"DOI":"10.1016\/j.xkme.2024.100962","type":"journal-article","created":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:17:55Z","timestamp":1735690675000},"page":"100962","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":11,"title":["Acute Kidney Injury, Mild Cognitive Impairment, and Dementia: A Cohort Study of Patients from SPRINT"],"prefix":"10.1016","volume":"7","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9364-3256","authenticated-orcid":false,"given":"Kristen L.","family":"Nowak","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anna","family":"Ostrow","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ester S.","family":"Oh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhiying","family":"You","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michel","family":"Chonchol","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"10212","key":"10.1016\/j.xkme.2024.100962_bib1","doi-asserted-by":"crossref","first-page":"1949","DOI":"10.1016\/S0140-6736(19)32563-2","article-title":"Acute kidney injury","volume":"394","author":"Ronco","year":"2019","journal-title":"Lancet"},{"issue":"1","key":"10.1016\/j.xkme.2024.100962_bib2","doi-asserted-by":"crossref","first-page":"160","DOI":"10.1016\/j.kint.2018.08.036","article-title":"Long-term risk of adverse outcomes after acute kidney injury: a systematic review and meta-analysis of cohort studies using consensus definitions of exposure","volume":"95","author":"See","year":"2019","journal-title":"Kidney Int"},{"issue":"6","key":"10.1016\/j.xkme.2024.100962_bib3","doi-asserted-by":"crossref","first-page":"961","DOI":"10.1053\/j.ajkd.2008.11.034","article-title":"Long-term risk of mortality and other adverse outcomes after acute kidney injury: a systematic review and meta-analysis","volume":"53","author":"Coca","year":"2009","journal-title":"Am J Kidney Dis"},{"issue":"9","key":"10.1016\/j.xkme.2024.100962_bib4","doi-asserted-by":"crossref","first-page":"1482","DOI":"10.2215\/CJN.00710113","article-title":"World incidence of AKI: a meta-analysis","volume":"8","author":"Susantitaphong","year":"2013","journal-title":"Clin J Am Soc Nephrol"},{"issue":"7","key":"10.1016\/j.xkme.2024.100962_bib5","doi-asserted-by":"crossref","first-page":"1904","DOI":"10.1097\/01.ASN.0000131529.60019.FA","article-title":"Moderate renal impairment and risk of dementia among older adults: the Cardiovascular Health Cognition Study","volume":"15","author":"Seliger","year":"2004","journal-title":"J\u00a0Am Soc Nephrol"},{"issue":"6","key":"10.1016\/j.xkme.2024.100962_bib6","doi-asserted-by":"crossref","first-page":"883","DOI":"10.1007\/s11011-020-00561-y","article-title":"Association between chronic kidney disease and Alzheimer's disease: an update","volume":"35","author":"Zhang","year":"2020","journal-title":"Metab Brain Dis"},{"issue":"6","key":"10.1016\/j.xkme.2024.100962_bib7","doi-asserted-by":"crossref","first-page":"798","DOI":"10.1002\/ana.21383","article-title":"Cystatin C as a marker of cognitive function in elders: findings from the health ABC study","volume":"63","author":"Yaffe","year":"2008","journal-title":"Ann Neurol"},{"issue":"10","key":"10.1016\/j.xkme.2024.100962_bib8","doi-asserted-by":"crossref","first-page":"3144","DOI":"10.1093\/ndt\/gfp230","article-title":"Chronic kidney disease is associated with incident cognitive impairment in the elderly: the INVADE study","volume":"24","author":"Etgen","year":"2009","journal-title":"Nephrol Dial Transplant"},{"issue":"1","key":"10.1016\/j.xkme.2024.100962_bib9","doi-asserted-by":"crossref","first-page":"258","DOI":"10.1186\/s13054-022-04131-9","article-title":"Acute kidney injury-associated delirium: a review of clinical and pathophysiological mechanisms","volume":"26","author":"Pang","year":"2022","journal-title":"Crit Care"},{"issue":"4","key":"10.1016\/j.xkme.2024.100962_bib10","doi-asserted-by":"crossref","first-page":"495","DOI":"10.1053\/j.ajkd.2022.02.015","article-title":"Association between acute kidney injury and dementia in the Atherosclerosis Risk in Communities (ARIC) Study","volume":"80","author":"Tung","year":"2022","journal-title":"Am J Kidney Dis"},{"issue":"10","key":"10.1016\/j.xkme.2024.100962_bib11","doi-asserted-by":"crossref","first-page":"1491","DOI":"10.1016\/j.ekir.2019.07.012","article-title":"Acute kidney injury is associated with an increased risk of dementia","volume":"4","author":"Kendrick","year":"2019","journal-title":"Kidney Int Rep"},{"issue":"6","key":"10.1016\/j.xkme.2024.100962_bib12","doi-asserted-by":"crossref","first-page":"R233","DOI":"10.1186\/cc11901","article-title":"Risk factors for dementia after critical illness in elderly Medicare beneficiaries","volume":"16","author":"Guerra","year":"2012","journal-title":"Crit Care"},{"issue":"2","key":"10.1016\/j.xkme.2024.100962_bib13","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0171671","article-title":"Increased risk of dementia in patients hospitalized with acute kidney injury: A nationwide population-based cohort study","volume":"12","author":"Tsai","year":"2017","journal-title":"PLOS One"},{"issue":"3","key":"10.1016\/j.xkme.2024.100962_bib14","doi-asserted-by":"crossref","first-page":"352","DOI":"10.1053\/j.ajkd.2017.08.021","article-title":"Effects of Intensive blood pressure treatment on acute kidney injury events in the Systolic Blood Pressure Intervention Trial (SPRINT)","volume":"71","author":"Rocco","year":"2018","journal-title":"Am J Kidney Dis"},{"issue":"22","key":"10.1016\/j.xkme.2024.100962_bib15","doi-asserted-by":"crossref","first-page":"2103","DOI":"10.1056\/NEJMoa1511939","article-title":"A\u00a0randomized trial of intensive versus standard blood-pressure control","volume":"373","author":"SPRINT Research Group","year":"2015","journal-title":"N\u00a0Engl J Med"},{"issue":"5","key":"10.1016\/j.xkme.2024.100962_bib16","doi-asserted-by":"crossref","first-page":"532","DOI":"10.1177\/1740774514537404","article-title":"The design and rationale of a multicenter clinical trial comparing two strategies for control of systolic blood pressure: The Systolic Blood Pressure Intervention Trial (SPRINT)","volume":"11","author":"Ambrosius","year":"2014","journal-title":"Clin Trials"},{"issue":"6","key":"10.1016\/j.xkme.2024.100962_bib17","doi-asserted-by":"crossref","first-page":"553","DOI":"10.1001\/jama.2018.21442","article-title":"Effect of intensive vs standard blood pressure control on probable dementia: A randomized clinical trial","volume":"321","author":"Williamson","year":"2019","journal-title":"JAMA"},{"issue":"7","key":"10.1016\/j.xkme.2024.100962_bib19","doi-asserted-by":"crossref","first-page":"1360","DOI":"10.1681\/ASN.2007080901","article-title":"Acute kidney injury leads to inflammation and functional changes in the brain","volume":"19","author":"Liu","year":"2008","journal-title":"J\u00a0Am Soc Nephrol"},{"issue":"3","key":"10.1016\/j.xkme.2024.100962_bib20","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1159\/000151433","article-title":"Effects of VEGF on the blood-brain barrier disruption caused by hyperosmolarity","volume":"82","author":"Chi","year":"2008","journal-title":"Pharmacology"},{"issue":"1-2","key":"10.1016\/j.xkme.2024.100962_bib21","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1007\/s11010-011-1001-4","article-title":"The association of receptor of advanced glycated end products and inflammatory mediators contributes to endothelial dysfunction in a prospective study of acute kidney injury patients with sepsis","volume":"359","author":"Sadik","year":"2012","journal-title":"Mol Cell Biochem"},{"issue":"6","key":"10.1016\/j.xkme.2024.100962_bib22","doi-asserted-by":"crossref","first-page":"846","DOI":"10.1053\/j.ajkd.2018.03.028","article-title":"Distant organ dysfunction in acute kidney injury: a review","volume":"72","author":"Lee","year":"2018","journal-title":"Am J Kidney Dis"},{"issue":"3","key":"10.1016\/j.xkme.2024.100962_bib23","doi-asserted-by":"crossref","first-page":"466","DOI":"10.1016\/j.kint.2019.10.032","article-title":"Crosstalk between the nervous system and the kidney","volume":"97","author":"Tanaka","year":"2020","journal-title":"Kidney Int"},{"issue":"4","key":"10.1016\/j.xkme.2024.100962_bib24","first-page":"201","article-title":"Long-term risk of dementia following acute kidney injury: A population-based study","volume":"29","author":"Kao","year":"2017","journal-title":"Ci Ji Yi Xue Za Zhi"},{"issue":"6","key":"10.1016\/j.xkme.2024.100962_bib25","doi-asserted-by":"crossref","first-page":"524","DOI":"10.1001\/jama.2019.10551","article-title":"Association of intensive vs standard blood pressure control with cerebral white matter lesions","volume":"322","author":"SPRINT MIND Investigators for the SPRINT Research Group","year":"2019","journal-title":"JAMA"}],"container-title":["Kidney Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2590059524001730?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2590059524001730?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,3,7]],"date-time":"2025-03-07T10:38:51Z","timestamp":1741343931000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2590059524001730"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,3]]},"references-count":24,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2025,3]]}},"alternative-id":["S2590059524001730"],"URL":"https:\/\/doi.org\/10.1016\/j.xkme.2024.100962","relation":{},"ISSN":["2590-0595"],"issn-type":[{"value":"2590-0595","type":"print"}],"subject":[],"published":{"date-parts":[[2025,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Acute Kidney Injury, Mild Cognitive Impairment, and Dementia: A Cohort Study of Patients from SPRINT","name":"articletitle","label":"Article Title"},{"value":"Kidney Medicine","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.xkme.2024.100962","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 The Authors. Published by Elsevier Inc. on behalf of the National Kidney Foundation, Inc.","name":"copyright","label":"Copyright"}],"article-number":"100962"}}