{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T08:26:41Z","timestamp":1786955201614,"version":"build-2736575974"},"reference-count":35,"publisher":"Elsevier BV","issue":"8","license":[{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,6,11]],"date-time":"2026-06-11T00:00:00Z","timestamp":1781136000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100002858","name":"China Postdoctoral Science Foundation","doi-asserted-by":"publisher","award":["2025M772055"],"award-info":[{"award-number":["2025M772055"]}],"id":[{"id":"10.13039\/501100002858","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82501334"],"award-info":[{"award-number":["82501334"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82471115"],"award-info":[{"award-number":["82471115"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82271115"],"award-info":[{"award-number":["82271115"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","ophthalmologyscience.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Ophthalmology Science"],"published-print":{"date-parts":[[2026,8]]},"DOI":"10.1016\/j.xops.2026.101290","type":"journal-article","created":{"date-parts":[[2026,6,16]],"date-time":"2026-06-16T16:35:44Z","timestamp":1781627744000},"page":"101290","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"title":["Altered Spontaneous Brain Activity in Adolescents and Adults with Comitant Strabismus and Strabismic Amblyopia"],"prefix":"10.1016","volume":"6","author":[{"given":"Yiru","family":"Huang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zitian","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yanyan","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daming","family":"Deng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Minbin","family":"Yu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"10","key":"10.1016\/j.xops.2026.101290_bib1","doi-asserted-by":"crossref","first-page":"856","DOI":"10.1001\/jama.2023.0052","article-title":"What is strabismus?","volume":"329","author":"Kraus","year":"2023","journal-title":"JAMA"},{"issue":"2","key":"10.1016\/j.xops.2026.101290_bib2","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1080\/09273972.2019.1604773","article-title":"Global and regional prevalence of strabismus: a comprehensive systematic review and meta-analysis","volume":"27","author":"Hashemi","year":"2019","journal-title":"Strabismus"},{"issue":"3","key":"10.1016\/j.xops.2026.101290_bib3","doi-asserted-by":"crossref","first-page":"P136","DOI":"10.1016\/j.ophtha.2022.11.003","article-title":"Amblyopia preferred practice pattern","volume":"130","author":"Cruz","year":"2023","journal-title":"Ophthalmology"},{"issue":"3","key":"10.1016\/j.xops.2026.101290_bib4","doi-asserted-by":"crossref","first-page":"P179","DOI":"10.1016\/j.ophtha.2022.11.002","article-title":"Esotropia and Exotropia preferred practice pattern\u00ae","volume":"130","author":"Sprunger","year":"2023","journal-title":"Ophthalmology"},{"issue":"6","key":"10.1016\/j.xops.2026.101290_bib5","doi-asserted-by":"crossref","first-page":"1051","DOI":"10.1016\/j.survophthal.2021.03.005","article-title":"The impact of strabismus on psychosocial heath and quality of life: a systematic review","volume":"66","author":"Buffenn","year":"2021","journal-title":"Surv Ophthalmol"},{"issue":"3","key":"10.1016\/j.xops.2026.101290_bib6","doi-asserted-by":"crossref","first-page":"316","DOI":"10.1080\/02713683.2018.1540642","article-title":"Altered functional connectivity of the primary visual cortex in Adult comitant strabismus: a resting-state functional MRI Study","volume":"44","author":"Yan","year":"2019","journal-title":"Curr Eye Res"},{"issue":"3","key":"10.1016\/j.xops.2026.101290_bib7","doi-asserted-by":"crossref","first-page":"3276","DOI":"10.3892\/mmr.2017.7006","article-title":"The atrophy of white and gray matter volume in patients with comitant strabismus: evidence from a voxel-based morphometry study","volume":"16","author":"Ouyang","year":"2017","journal-title":"Mol Med Rep"},{"issue":"12","key":"10.1016\/j.xops.2026.101290_bib8","doi-asserted-by":"crossref","first-page":"1386","DOI":"10.1080\/02713683.2019.1639767","article-title":"Cortical alterations by the abnormal visual experience beyond the critical period: a resting-state fMRI Study on constant exotropia","volume":"44","author":"Shi","year":"2019","journal-title":"Curr Eye Res"},{"key":"10.1016\/j.xops.2026.101290_bib9","first-page":"1243","article-title":"A functional MRI study of altered spontaneous brain activity pattern in patients with congenital comitant strabismus using amplitude of low-frequency fluctuation","volume":"12","author":"Tan","year":"2016","journal-title":"Neuropsychiatr Dis Treat"},{"key":"10.1016\/j.xops.2026.101290_bib10","doi-asserted-by":"crossref","DOI":"10.1016\/j.exer.2022.109161","article-title":"Altered spontaneous brain activity in patients with comitant exotropia before and after surgery: a resting-state fMRI study","volume":"222","author":"Wu","year":"2022","journal-title":"Exp Eye Res"},{"key":"10.1016\/j.xops.2026.101290_bib11","doi-asserted-by":"crossref","DOI":"10.3389\/fnhum.2023.1095431","article-title":"Altered interhemispheric functional connectivity in patients with comitant exotropia before and after surgery: a resting-state fMRI study","volume":"17","author":"Chen","year":"2023","journal-title":"Front In Hum Neurosci"},{"issue":"1","key":"10.1016\/j.xops.2026.101290_bib12","doi-asserted-by":"crossref","first-page":"392","DOI":"10.1177\/0300060517715340","article-title":"Altered brain network centrality in patients with adult comitant exotropia strabismus: a resting-state fMRI study","volume":"46","author":"Tan","year":"2018","journal-title":"J Int Med Res"},{"issue":"6","key":"10.1016\/j.xops.2026.101290_bib13","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0010931","article-title":"Dorsal visual pathway changes in patients with comitant extropia","volume":"5","author":"Yan","year":"2010","journal-title":"PLoS One"},{"issue":"5","key":"10.1016\/j.xops.2026.101290_bib14","doi-asserted-by":"crossref","first-page":"453","DOI":"10.1227\/NEU.0000000000000307","article-title":"Resting-State functional magnetic resonance imaging: review of neurosurgical applications","volume":"74","author":"Lang","year":"2014","journal-title":"Neurosurgery"},{"issue":"1","key":"10.1016\/j.xops.2026.101290_bib15","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1016\/j.jneumeth.2008.04.012","article-title":"An improved approach to detection of amplitude of low-frequency fluctuation (ALFF) for resting-state fMRI: fractional ALFF","volume":"172","author":"Zou","year":"2008","journal-title":"J Neurosci Methods"},{"key":"10.1016\/j.xops.2026.101290_bib16","doi-asserted-by":"crossref","first-page":"279","DOI":"10.3389\/fnins.2019.00279","article-title":"Sampling rate effects on resting State fMRI metrics","volume":"13","author":"Huotari","year":"2019","journal-title":"Front Neurosci"},{"key":"10.1016\/j.xops.2026.101290_bib17","doi-asserted-by":"crossref","first-page":"196","DOI":"10.3389\/fnhum.2014.00196","article-title":"Studying the spatial distribution of physiological effects on BOLD signals using ultrafast fMRI","volume":"8","author":"Tong","year":"2014","journal-title":"Front Hum Neurosci"},{"key":"10.1016\/j.xops.2026.101290_bib18","doi-asserted-by":"crossref","first-page":"2351","DOI":"10.2147\/NDT.S171462","article-title":"Altered spontaneous brain activity patterns in strabismus with amblyopia patients using amplitude of low-frequency fluctuation: a resting-state fMRI study","volume":"14","author":"Min","year":"2018","journal-title":"Neuropsychiatr Dis Treat"},{"issue":"2","key":"10.1016\/j.xops.2026.101290_bib19","doi-asserted-by":"crossref","first-page":"175","DOI":"10.3758\/BF03193146","article-title":"G\u2217Power 3: a flexible statistical power analysis program for the social, behavioral, and biomedical sciences","volume":"39","author":"Faul","year":"2007","journal-title":"Behav Res Methods"},{"issue":"1","key":"10.1016\/j.xops.2026.101290_bib20","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1037\/0033-2909.112.1.155","article-title":"A power primer","volume":"112","author":"Cohen","year":"1992","journal-title":"Psychol Bull"},{"key":"10.1016\/j.xops.2026.101290_bib21","doi-asserted-by":"crossref","DOI":"10.1016\/j.jclinepi.2025.112101","article-title":"Empirical simulation of internal validation methods for prediction models: comparing k-fold cross-validation with bootstrap-based optimism correction","volume":"190","author":"Zhang","year":"2026","journal-title":"J Clin Epidemiol"},{"key":"10.1016\/j.xops.2026.101290_bib22","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1146\/annurev-vision-091718-015000","article-title":"Role of the vermal cerebellum in visually guided eye movements and visual motion perception","volume":"5","author":"Thier","year":"2019","journal-title":"Annu Rev Vis Sci"},{"issue":"6","key":"10.1016\/j.xops.2026.101290_bib23","doi-asserted-by":"crossref","first-page":"387","DOI":"10.1016\/j.eurpsy.2007.02.006","article-title":"Insular cortex and neuropsychiatric disorders: a review of recent literature","volume":"22","author":"Nagai","year":"2007","journal-title":"Eur Psychiatry"},{"key":"10.1016\/j.xops.2026.101290_bib24","doi-asserted-by":"crossref","DOI":"10.3389\/fnhum.2021.777762","article-title":"Altered brain structure and spontaneous functional activity in children with Concomitant strabismus","volume":"15","author":"Yin","year":"2021","journal-title":"Front Hum Neurosci"},{"key":"10.1016\/j.xops.2026.101290_bib25","doi-asserted-by":"crossref","DOI":"10.1155\/2019\/6817839","article-title":"Visuomotor behaviour in amblyopia: deficits and compensatory adaptations","volume":"2019","author":"Niechwiej-Szwedo","year":"2019","journal-title":"Neural Plast"},{"issue":"1","key":"10.1016\/j.xops.2026.101290_bib26","doi-asserted-by":"crossref","first-page":"3858","DOI":"10.1038\/s41598-018-21620-6","article-title":"Spatial summation across the visual field in strabismic and anisometropic amblyopia","volume":"8","author":"Je","year":"2018","journal-title":"Sci Rep"},{"key":"10.1016\/j.xops.2026.101290_bib27","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1016\/j.preteyeres.2012.11.001","article-title":"Amblyopia and binocular vision","volume":"33","author":"Birch","year":"2013","journal-title":"Prog Retin Eye Res"},{"key":"10.1016\/j.xops.2026.101290_bib28","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1016\/j.exer.2018.07.013","article-title":"Fixation instability during binocular viewing in anisometropic and strabismic children","volume":"183","author":"Kelly","year":"2019","journal-title":"Exp Eye Res"},{"issue":"5","key":"10.1016\/j.xops.2026.101290_bib29","doi-asserted-by":"crossref","first-page":"297","DOI":"10.3928\/01913913-20190726-01","article-title":"Eye tracking abnormalities in school-aged children with Strabismus and with and without amblyopia","volume":"56","author":"Al-Haddad","year":"2019","journal-title":"J Pediatr Ophthalmol Strabismus"},{"issue":"2","key":"10.1016\/j.xops.2026.101290_bib30","doi-asserted-by":"crossref","first-page":"21.1","DOI":"10.1167\/7.2.21","article-title":"Amblyopic reading is crowded","volume":"7","author":"Levi","year":"2007","journal-title":"J Vis"},{"issue":"7","key":"10.1016\/j.xops.2026.101290_bib31","first-page":"526","article-title":"Clinical observation of spontaneous brain activity in children with congenital cortical cataract amblyopia","volume":"59","author":"Li","year":"2023","journal-title":"Zhonghua Yan Ke Za Zhi"},{"key":"10.1016\/j.xops.2026.101290_bib32","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1016\/j.conb.2017.10.023","article-title":"Neural mechanisms of movement planning: motor cortex and beyond","volume":"49","author":"Svoboda","year":"2018","journal-title":"Curr Opin Neurobiol"},{"key":"10.1016\/j.xops.2026.101290_bib33","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.cortex.2013.02.001","article-title":"Visual interhemispheric communication and callosal connections of the occipital lobes","volume":"56","author":"Berlucchi","year":"2014","journal-title":"Cortex"},{"issue":"46","key":"10.1016\/j.xops.2026.101290_bib34","doi-asserted-by":"crossref","first-page":"9197","DOI":"10.1523\/JNEUROSCI.1786-19.2019","article-title":"Functional localization of the frontal eye fields in the common marmoset using microstimulation","volume":"39","author":"Selvanayagam","year":"2019","journal-title":"J Neurosci"},{"key":"10.1016\/j.xops.2026.101290_bib35","article-title":"Functional deficits and structural changes associated with the visual attention network during resting State in adult strabismic and anisometropic amblyopes","volume":"16","author":"Wang","year":"2022","journal-title":"Front Hum Neurosci"}],"container-title":["Ophthalmology Science"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2666914526002289?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2666914526002289?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T08:12:54Z","timestamp":1786954374000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2666914526002289"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,8]]},"references-count":35,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2026,8]]}},"alternative-id":["S2666914526002289"],"URL":"https:\/\/doi.org\/10.1016\/j.xops.2026.101290","relation":{},"ISSN":["2666-9145"],"issn-type":[{"value":"2666-9145","type":"print"}],"subject":[],"published":{"date-parts":[[2026,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Altered Spontaneous Brain Activity in Adolescents and Adults with Comitant Strabismus and Strabismic Amblyopia","name":"articletitle","label":"Article Title"},{"value":"Ophthalmology Science","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.xops.2026.101290","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 American Academy of Ophthalmology, Inc. Published by Elsevier Inc.","name":"copyright","label":"Copyright"}],"article-number":"101290"}}