{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T09:48:40Z","timestamp":1792057720631,"version":"4.4.0"},"reference-count":25,"publisher":"Elsevier BV","issue":"10","license":[{"start":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,8,13]],"date-time":"2026-08-13T00:00:00Z","timestamp":1786579200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","ophthalmologyscience.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Ophthalmology Science"],"published-print":{"date-parts":[[2026,10]]},"DOI":"10.1016\/j.xops.2026.101377","type":"journal-article","created":{"date-parts":[[2026,8,19]],"date-time":"2026-08-19T07:06:03Z","timestamp":1787123163000},"page":"101377","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"title":["Patterns of Choroidal Configuration in Pachychoroid Spectrum Disease"],"prefix":"10.1016","volume":"6","author":[{"ORCID":"https:\/\/orcid.org\/0009-0002-1227-7819","authenticated-orcid":false,"given":"Vesna","family":"Bosic","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1590-4868","authenticated-orcid":false,"given":"Isabel","family":"Weinstein","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9701-8204","authenticated-orcid":false,"given":"Berthold","family":"Seitz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alaa Din","family":"Abdin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.xops.2026.101377_bib1","doi-asserted-by":"crossref","first-page":"819","DOI":"10.1038\/s41433-024-03253-4","article-title":"Pachychoroid disease: review and update","volume":"39","author":"Cheung","year":"2025","journal-title":"Eye"},{"key":"10.1016\/j.xops.2026.101377_bib2","doi-asserted-by":"crossref","first-page":"865","DOI":"10.1007\/s00347-021-01379-4","article-title":"Uniform classification of the pachychoroid spectrum disorders","volume":"118","author":"Abdin","year":"2021","journal-title":"Ophthalmologe"},{"key":"10.1016\/j.xops.2026.101377_bib3","doi-asserted-by":"crossref","first-page":"344","DOI":"10.1038\/s41598-024-82745-5","article-title":"Quantitative analysis of choroidal vascular structures and anatomical changes in pachychoroid spectrum diseases using ultra-widefield SS-OCTA","volume":"15","author":"Xiao","year":"2025","journal-title":"Sci Rep"},{"key":"10.1016\/j.xops.2026.101377_bib4","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0289186","article-title":"Choroidal vascularity index in different types of central serous chorioretinopathy: a meta-analysis","volume":"18","author":"Xia","year":"2023","journal-title":"Plos One"},{"key":"10.1016\/j.xops.2026.101377_bib5","doi-asserted-by":"crossref","first-page":"1395","DOI":"10.1097\/IAE.0000000000002585","article-title":"Use of choroidal vascularity index for choroidal structural evaluation in central serous chorioretinopathy with choroidal neovascularization","volume":"40","author":"Kim","year":"2020","journal-title":"Retina"},{"key":"10.1016\/j.xops.2026.101377_bib6","doi-asserted-by":"crossref","first-page":"482","DOI":"10.1007\/s10384-021-00829-5","article-title":"A comparative study on the choroidal vascularity index and the determination of cut-off values in the pachychoroid spectrum diseases","volume":"65","author":"Demirel","year":"2021","journal-title":"Jpn J Ophthalmol"},{"key":"10.1016\/j.xops.2026.101377_bib7","doi-asserted-by":"crossref","first-page":"1191","DOI":"10.1177\/11206721231210755","article-title":"Choroidal features in non-neovascular and neovascular pachychoroid diseases","volume":"34","author":"Hachicha","year":"2024","journal-title":"Eur J Ophthalmol"},{"key":"10.1016\/j.xops.2026.101377_bib8","doi-asserted-by":"crossref","first-page":"1344","DOI":"10.4103\/IJO.IJO_450_25","article-title":"Central serous chorioretinopathy imaging biomarkers as potential indicators of response to subthreshold nanosecond laser","volume":"73","author":"Bosic","year":"2025","journal-title":"Indian J Ophthalmol"},{"key":"10.1016\/j.xops.2026.101377_bib9","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1186\/s40942-020-00214-3","article-title":"Efficacy of nanosecond laser treatment in central serous chorioretinopathy with and without atrophy of retinal pigment epithelium","volume":"6","author":"Kaymak","year":"2020","journal-title":"Int J Retina Vitreous"},{"key":"10.1016\/j.xops.2026.101377_bib10","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1167\/tvst.12.9.17","article-title":"Choroidal vortex vein drainage system in central serous chorioretinopathy using ultra-widefield optical coherence tomography angiography","volume":"12","author":"Luo","year":"2023","journal-title":"Transl Vis Sci Technol"},{"key":"10.1016\/j.xops.2026.101377_bib11","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1016\/j.ajo.2016.06.043","article-title":"Increased choroidal vascularity in central serous chorioretinopathy quantified using swept-source optical coherence tomography","volume":"169","author":"Kuroda","year":"2016","journal-title":"Am J Ophthalmol"},{"key":"10.1016\/j.xops.2026.101377_bib12","doi-asserted-by":"crossref","first-page":"9907","DOI":"10.1038\/s41598-025-94096-w","article-title":"Choroidal blood flow changes in central serous chorioretinopathy","volume":"15","author":"Xu","year":"2025","journal-title":"Sci Rep"},{"key":"10.1016\/j.xops.2026.101377_bib13","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1007\/s00417-018-4179-2","article-title":"Choriocapillaris flow features and choroidal vasculature in the fellow eyes of patients with acute central serous chorioretinopathy","volume":"257","author":"Yun","year":"2019","journal-title":"Graefes Arch Clin Exp Ophthalmol"},{"key":"10.1016\/j.xops.2026.101377_bib14","doi-asserted-by":"crossref","first-page":"1983","DOI":"10.1097\/IAE.0000000000004190","article-title":"Comparison of choroidal vasculature between central serous chorioretinopathy with and without thick choroid using swept-source optical coherence tomography angiography","volume":"44","author":"Zeng","year":"2024","journal-title":"Retina"},{"key":"10.1016\/j.xops.2026.101377_bib15","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1007\/s00417-019-04524-7","article-title":"Three-dimensional choroidal vascularity index in acute central serous chorioretinopathy using swept-source optical coherence tomography","volume":"258","author":"Yang","year":"2020","journal-title":"Graefes Arch Clin Exp Ophthalmol"},{"key":"10.1016\/j.xops.2026.101377_bib16","doi-asserted-by":"crossref","first-page":"337","DOI":"10.1007\/s00417-025-07014-1","article-title":"Volumetric choroidal biomarkers in central serous chorioretinopathy using swept-source optical coherence tomography: a deep learning approach","volume":"264","author":"Valsecchi","year":"2025","journal-title":"Graefes Arch Clin Exp Ophthalmol"},{"key":"10.1016\/j.xops.2026.101377_bib17","doi-asserted-by":"crossref","first-page":"1646","DOI":"10.1097\/IAE.0000000000001040","article-title":"Choroidal vascularity index in central serous chorioretinopathy","volume":"36","author":"Agrawal","year":"2016","journal-title":"Retina"},{"key":"10.1016\/j.xops.2026.101377_bib18","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1007\/s00417-021-05380-0","article-title":"Morphological differences of choroid in central serous chorioretinopathy determined by ultra-widefield optical coherence tomography","volume":"260","author":"Izumi","year":"2022","journal-title":"Graefes Arch Clin Exp Ophthalmol"},{"key":"10.1016\/j.xops.2026.101377_bib19","doi-asserted-by":"crossref","DOI":"10.1038\/s41598-022-23389-1","article-title":"Quantitative analysis of choroidal vasculature in central serous chorioretinopathy using ultra-widefield swept-source optical coherence tomography angiography","volume":"12","author":"Zeng","year":"2022","journal-title":"Sci Rep"},{"key":"10.1016\/j.xops.2026.101377_bib20","doi-asserted-by":"crossref","DOI":"10.3389\/fmed.2022.967369","article-title":"Three-dimensional choroidal vascularity index in central serous chorioretinopathy using ultra-widefield swept-source optical coherence tomography angiography","volume":"9","author":"Zeng","year":"2022","journal-title":"Front Med"},{"key":"10.1016\/j.xops.2026.101377_bib21","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0206646","article-title":"Geographic filling delay of the choriocapillaris in the region of dilated asymmetric vortex veins in central serous chorioretinopathy","volume":"13","author":"Kishi","year":"2018","journal-title":"PLoS One"},{"key":"10.1016\/j.xops.2026.101377_bib22","doi-asserted-by":"crossref","first-page":"938","DOI":"10.1016\/j.oret.2020.03.024","article-title":"Vortex vein anastomosis at the watershed in pachychoroid spectrum diseases","volume":"4","author":"Matsumoto","year":"2020","journal-title":"Ophthalmol Retina"},{"key":"10.1016\/j.xops.2026.101377_bib23","doi-asserted-by":"crossref","first-page":"902","DOI":"10.1007\/s10384-025-01230-2","article-title":"Reduction in choroidal thickness associated with the progression of pachychoroid spectrum diseases","volume":"69","author":"Matsumoto","year":"2025","journal-title":"Jpn J Ophthalmol"},{"key":"10.1016\/j.xops.2026.101377_bib24","doi-asserted-by":"crossref","first-page":"920","DOI":"10.1097\/IAE.0000000000004753","article-title":"A deeper assessment of various choroidal and demographic biomarkers among symptomatic pachychoroid spectrum entities within a tertiary referral center","volume":"46","author":"Bosic","year":"2026","journal-title":"Retina"},{"key":"10.1016\/j.xops.2026.101377_bib25","doi-asserted-by":"crossref","first-page":"997","DOI":"10.1097\/IAE.0000000000003004","article-title":"Intervortex venous anastomosis in pachychoroid-related disorders","volume":"41","author":"Spaide","year":"2021","journal-title":"Retina"}],"container-title":["Ophthalmology Science"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2666914526003155?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2666914526003155?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T09:23:45Z","timestamp":1792056225000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2666914526003155"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,10]]},"references-count":25,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2026,10]]}},"alternative-id":["S2666914526003155"],"URL":"https:\/\/doi.org\/10.1016\/j.xops.2026.101377","relation":{},"ISSN":["2666-9145"],"issn-type":[{"value":"2666-9145","type":"print"}],"subject":[],"published":{"date-parts":[[2026,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Patterns of Choroidal Configuration in Pachychoroid Spectrum Disease","name":"articletitle","label":"Article Title"},{"value":"Ophthalmology Science","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.xops.2026.101377","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 American Academy of Ophthalmology, Inc. Published by Elsevier Inc.","name":"copyright","label":"Copyright"}],"article-number":"101377"}}