{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,18]],"date-time":"2026-07-18T13:21:11Z","timestamp":1784380871807,"version":"3.55.0"},"reference-count":33,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2019,1,1]],"date-time":"2019-01-01T00:00:00Z","timestamp":1546300800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2019,1,1]],"date-time":"2019-01-01T00:00:00Z","timestamp":1546300800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/100008901","name":"College of Pharmacy","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100008901","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["jpharmsci.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Pharmaceutical Sciences"],"published-print":{"date-parts":[[2019,1]]},"DOI":"10.1016\/j.xphs.2018.06.018","type":"journal-article","created":{"date-parts":[[2018,6,26]],"date-time":"2018-06-26T21:07:56Z","timestamp":1530047276000},"page":"173-177","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":7,"title":["Thermodynamic Evaluation of the Interaction Driven by Hydrophobic Bonding in the Aqueous Phase"],"prefix":"10.1016","volume":"108","author":[{"given":"Peng","family":"Yu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dale Eric","family":"Wurster","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"50","key":"10.1016\/j.xphs.2018.06.018_bib1","doi-asserted-by":"crossref","first-page":"14846","DOI":"10.1021\/ja028539f","article-title":"Hydrophobic interaction and hydrogen bonding cooperatively confer a vancomycin hydrogel: a potential candidate for biomaterials","volume":"124","author":"Xing","year":"2002","journal-title":"J\u00a0Am Chem Soc"},{"issue":"4","key":"10.1016\/j.xphs.2018.06.018_bib2","doi-asserted-by":"crossref","first-page":"681","DOI":"10.1021\/ja963036t","article-title":"Influenza neuraminidase inhibitors possessing a novel hydrophobic interaction in the enzyme active site: design, synthesis, and structural analysis of carbocyclic sialic acid analogues with potent anti-influenza activity","volume":"119","author":"Kim","year":"1997","journal-title":"J\u00a0Am Chem Soc"},{"issue":"1-2","key":"10.1016\/j.xphs.2018.06.018_bib3","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1016\/0021-9673(92)85472-6","article-title":"High-performance hydrophobic interaction chromatography as a tool for protein refolding","volume":"599","author":"Geng","year":"1992","journal-title":"J\u00a0Chromatogr A"},{"key":"10.1016\/j.xphs.2018.06.018_bib4","volume":"PART II Chromatography","author":"Janson","year":"2012"},{"issue":"2","key":"10.1016\/j.xphs.2018.06.018_bib5","doi-asserted-by":"crossref","first-page":"279","DOI":"10.1016\/0021-9673(93)83340-X","article-title":"High-performance membrane chromatography: highly efficient separation method for proteins in ion-exchange, hydrophobic interaction and reversed-phase modes","volume":"646","author":"Tennikova","year":"1993","journal-title":"J\u00a0Chromatogr A"},{"key":"10.1016\/j.xphs.2018.06.018_bib6","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1146\/annurev.physchem.58.032806.104445","article-title":"Dewetting and hydrophobic interaction in physical and biological systems","volume":"60","author":"Berne","year":"2009","journal-title":"Annu Rev Phys Chem"},{"issue":"8","key":"10.1016\/j.xphs.2018.06.018_bib7","doi-asserted-by":"crossref","first-page":"2691","DOI":"10.1091\/mbc.11.8.2691","article-title":"Specific sequence motif of 8-Cys repeats of TGF-\u03b2 binding proteins, LTBPs, creates a hydrophobic interaction surface for binding of small latent TGF-\u03b2","volume":"11","author":"Saharinen","year":"2000","journal-title":"Mol Biol Cell"},{"issue":"21","key":"10.1016\/j.xphs.2018.06.018_bib8","doi-asserted-by":"crossref","first-page":"8069","DOI":"10.1073\/pnas.83.21.8069","article-title":"Temperature dependence of the hydrophobic interaction in protein folding","volume":"83","author":"Baldwin","year":"1986","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.xphs.2018.06.018_bib9","first-page":"191","article-title":"Stability of protein structure and hydrophobic interaction","volume":"Vol. 39","author":"Privalov","year":"1988"},{"issue":"1","key":"10.1016\/j.xphs.2018.06.018_bib10","doi-asserted-by":"crossref","first-page":"110","DOI":"10.1016\/j.sbi.2003.12.001","article-title":"The interaction of proteins with solid surfaces","volume":"14","author":"Gray","year":"2004","journal-title":"Curr Opin Struct Biol"},{"issue":"1","key":"10.1016\/j.xphs.2018.06.018_bib11","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1016\/0079-6107(94)00008-W","article-title":"Protein-protein interactions: a review of protein dimer structures","volume":"63","author":"Jones","year":"1995","journal-title":"Prog Biophys Mol Biol"},{"issue":"4","key":"10.1016\/j.xphs.2018.06.018_bib12","doi-asserted-by":"crossref","first-page":"1055","DOI":"10.1016\/j.xphs.2017.11.017","article-title":"Thermodynamic estimate of the number of solvent molecules displaced by a solute molecule for enthalpy-driven adsorption: phenobarbital and activated carbons as the model system","volume":"107","author":"Yu","year":"2018","journal-title":"J\u00a0Pharm Sci"},{"key":"10.1016\/j.xphs.2018.06.018_bib13","series-title":"Adsorptivity and Surface Characterization of Activated Charcoals","author":"Burke","year":"1991"},{"issue":"1","key":"10.1016\/j.xphs.2018.06.018_bib14","doi-asserted-by":"crossref","first-page":"126","DOI":"10.1023\/A:1018900431661","article-title":"Surface characterization of activated charcoal by X-ray photoelectron-spectroscopy (XPS)\u2013correlation with phenobarbital adsorption data","volume":"9","author":"Burke","year":"1992","journal-title":"Pharm Res"},{"key":"10.1016\/j.xphs.2018.06.018_bib15","series-title":"Characterization of Activated Carbon Surface Composition by Isoperibol Calorimetry and X-Ray Photoelectron Spectroscopy","author":"Shmeis-Ziadeh","year":"1999"},{"issue":"12","key":"10.1016\/j.xphs.2018.06.018_bib16","doi-asserted-by":"crossref","DOI":"10.2471\/BLT.12.113183","article-title":"Phenobarbital: missing in action","volume":"90","author":"Ilangaratne","year":"2012","journal-title":"Bull World Health Organ"},{"key":"10.1016\/j.xphs.2018.06.018_bib17","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1111\/epi.12027","article-title":"Current position of phenobarbital in epilepsy and its future","volume":"53","author":"Brodie","year":"2012","journal-title":"Epilepsia"},{"issue":"17","key":"10.1016\/j.xphs.2018.06.018_bib18","doi-asserted-by":"crossref","first-page":"2400","DOI":"10.1001\/jama.1982.03320420050032","article-title":"Treatment of phenobarbital overdose with activated charcoal","volume":"247","author":"Goldberg","year":"1982","journal-title":"J\u00a0Am Med Assoc"},{"issue":"11","key":"10.1016\/j.xphs.2018.06.018_bib19","doi-asserted-by":"crossref","first-page":"642","DOI":"10.1056\/NEJM198209093071102","article-title":"Acceleration of the body clearance of phenobarbital by oral activated charcoal","volume":"307","author":"Berg","year":"1982","journal-title":"N\u00a0Engl J Med"},{"issue":"1","key":"10.1016\/j.xphs.2018.06.018_bib20","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1097\/00007691-198703000-00008","article-title":"Effect of charcoal and sorbitol-charcoal suspension on the elimination of intravenous phenobarbital","volume":"9","author":"Berg","year":"1987","journal-title":"Ther Drug Monit"},{"key":"10.1016\/j.xphs.2018.06.018_bib21","series-title":"Activated Carbon: Surface Chemistry and Adsorption from Solution","first-page":"vii","author":"Mattson","year":"1971"},{"key":"10.1016\/j.xphs.2018.06.018_bib22","series-title":"Adsorption from Solution at the Solid\/Liquid Interface","first-page":"416","author":"Parfitt","year":"1983"},{"key":"10.1016\/j.xphs.2018.06.018_bib23","series-title":"Modification of Surface Functional Groups on Activated Carbon: The Effects on the Adsorption of Phenobarbital from Aqueous Solutions","author":"Kolling","year":"1997"},{"issue":"8","key":"10.1016\/j.xphs.2018.06.018_bib24","doi-asserted-by":"crossref","first-page":"1021","DOI":"10.1016\/0008-6223(95)00030-H","article-title":"XPS of nitrogen-containing functional groups on activated carbon","volume":"33","author":"Jansen","year":"1995","journal-title":"Carbon"},{"key":"10.1016\/j.xphs.2018.06.018_bib25","series-title":"The Effects of Solvent and Surface Functionalities on the Adsorption of Phenobarbital from Solution by Modified Activated Carbons","author":"VanDer Kamp","year":"2001"},{"issue":"2","key":"10.1016\/j.xphs.2018.06.018_bib26","doi-asserted-by":"crossref","first-page":"228","DOI":"10.1023\/A:1015800322286","article-title":"Model selection for the adsorption of phenobarbital by activated charcoal","volume":"8","author":"Burke","year":"1991","journal-title":"Pharm Res"},{"key":"10.1016\/j.xphs.2018.06.018_bib27","unstructured":"Yu P, Wurster DE. Two-mechanism Langmuir-like equation for the adsorption of phenobarbital from solution by activated carbons. Poster presentation at the 2014 AAPS Annual Meeting and Exposition, San Diego, CA; November 5, 2014."},{"issue":"1","key":"10.1016\/j.xphs.2018.06.018_bib28","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1021\/la040093o","article-title":"Modified Langmuir-like model for modeling the adsorption from aqueous solutions by activated carbons","volume":"21","author":"VanDer Kamp","year":"2005","journal-title":"Langmuir"},{"key":"10.1016\/j.xphs.2018.06.018_bib29","series-title":"Interactions of Phenobarbital with Derivatized Activated Carbon Surfaces","author":"Aburub","year":"2004"},{"issue":"7","key":"10.1016\/j.xphs.2018.06.018_bib30","doi-asserted-by":"crossref","first-page":"1337","DOI":"10.1002\/bip.1975.360140704","article-title":"Hydrophobic interaction and structural changes in the solvent","volume":"14","author":"Ben-Naim","year":"1975","journal-title":"Biopolymers"},{"issue":"3","key":"10.1016\/j.xphs.2018.06.018_bib31","doi-asserted-by":"crossref","first-page":"379","DOI":"10.1016\/0022-2836(71)90324-X","article-title":"The interpretation of protein structures: estimation of static accessibility","volume":"55","author":"Lee","year":"1971","journal-title":"J\u00a0Mol Biol"},{"key":"10.1016\/j.xphs.2018.06.018_bib32","unstructured":"Yu P, Wurster DE. A fundamental understanding of the entropy-driven adsorption of Phenobarbital from solution by activated carbons. Poster presentation at the 2017 AAPS Annual Meeting and Exposition, San Diego, CA; November 15, 2017."},{"issue":"1","key":"10.1016\/j.xphs.2018.06.018_bib33","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1016\/j.jcis.2005.08.035","article-title":"Phenobarbital interactions with derivatized activated carbon surfaces","volume":"296","author":"Aburub","year":"2006","journal-title":"J\u00a0Colloid Interface Sci"}],"container-title":["Journal of Pharmaceutical Sciences"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022354918303526?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022354918303526?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,20]],"date-time":"2025-09-20T09:26:03Z","timestamp":1758360363000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0022354918303526"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,1]]},"references-count":33,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2019,1]]}},"alternative-id":["S0022354918303526"],"URL":"https:\/\/doi.org\/10.1016\/j.xphs.2018.06.018","relation":{},"ISSN":["0022-3549"],"issn-type":[{"value":"0022-3549","type":"print"}],"subject":[],"published":{"date-parts":[[2019,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Thermodynamic Evaluation of the Interaction Driven by Hydrophobic Bonding in the Aqueous Phase","name":"articletitle","label":"Article Title"},{"value":"Journal of Pharmaceutical Sciences","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.xphs.2018.06.018","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2019 American Pharmacists Association\u00ae. Published by Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}