{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T06:47:50Z","timestamp":1777445270529,"version":"3.51.4"},"reference-count":20,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2020,2,1]],"date-time":"2020-02-01T00:00:00Z","timestamp":1580515200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,2,1]],"date-time":"2020-02-01T00:00:00Z","timestamp":1580515200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100002873","name":"Chulalongkorn University","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100002873","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["jpharmsci.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Pharmaceutical Sciences"],"published-print":{"date-parts":[[2020,2]]},"DOI":"10.1016\/j.xphs.2019.11.010","type":"journal-article","created":{"date-parts":[[2019,11,18]],"date-time":"2019-11-18T11:21:47Z","timestamp":1574076107000},"page":"1153-1160","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":21,"title":["Enhanced Antipsoriatic Activity of Mycophenolic Acid Against the TNF-\u03b1-Induced HaCaT Cell Proliferation by Conjugated Poloxamer Micelles"],"prefix":"10.1016","volume":"109","author":[{"given":"Wiwat","family":"Supasena","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chawanphat","family":"Muangnoi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wuttinont","family":"Thaweesest","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chalermkiat","family":"Songkram","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Keisuke","family":"Ueda","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kenjirou","family":"Higashi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kunikazu","family":"Moribe","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Somboon","family":"Tanasupawat","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pornchai","family":"Rojsitthisak","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.xphs.2019.11.010_bib1","doi-asserted-by":"crossref","first-page":"531","DOI":"10.1016\/S0190-9622(79)80097-3","article-title":"Efficacy of mycophenolic acid for the treatment of psoriasis","volume":"1","author":"Gomez","year":"1979","journal-title":"J\u00a0Am Acad Dermatol"},{"key":"10.1016\/j.xphs.2019.11.010_bib2","doi-asserted-by":"crossref","first-page":"537","DOI":"10.1111\/1523-1747.ep12610346","article-title":"Treatment of psoriasis with oral mycophenolic acid","volume":"65","author":"Jones","year":"1975","journal-title":"J\u00a0Invest Dermatol"},{"key":"10.1016\/j.xphs.2019.11.010_bib3","doi-asserted-by":"crossref","first-page":"1203","DOI":"10.1001\/archderm.1977.01640090051004","article-title":"Mycophenolic acid for psoriasis","volume":"113","author":"Lynch","year":"1977","journal-title":"Arch Dermatol"},{"key":"10.1016\/j.xphs.2019.11.010_bib4","doi-asserted-by":"crossref","first-page":"1275","DOI":"10.1081\/DDC-120015361","article-title":"Influence of ferrous sulfate on the solubility, partition coefficient, and stability of mycophenolic acid and the ester mycophenolate mofetil","volume":"28","author":"Lidgate","year":"2002","journal-title":"Drug Dev Ind Pharm"},{"key":"10.1016\/j.xphs.2019.11.010_bib5","doi-asserted-by":"crossref","first-page":"445","DOI":"10.1016\/S0190-9622(18)30747-3","article-title":"Rediscovering mycophenolic acid: a review of its mechanism, side effects, and potential uses","volume":"37","author":"Kitchin","year":"1997","journal-title":"J\u00a0Am Acad Dermatol"},{"key":"10.1016\/j.xphs.2019.11.010_bib6","doi-asserted-by":"crossref","first-page":"605","DOI":"10.1046\/j.0306-5251.2001.01487.x","article-title":"The glucuronidation of mycophenolic acid by human liver, kidney and jejunum microsomes","volume":"52","author":"Bowalgaha","year":"2001","journal-title":"Br J Clin Pharmacol"},{"key":"10.1016\/j.xphs.2019.11.010_bib7","first-page":"984","article-title":"Glucuronidation associated with intrinsic resistance to mycophenolic acid in human colorectal carcinoma cells","volume":"56","author":"Franklin","year":"1996","journal-title":"Cancer Res"},{"key":"10.1016\/j.xphs.2019.11.010_bib8","doi-asserted-by":"crossref","first-page":"5206","DOI":"10.1002\/jps.22716","article-title":"Effects of different carboxylic ester spacers on chemical stability, release characteristics, and anticancer activity of mono-PEGylated curcumin conjugates","volume":"100","author":"Wichitnithad","year":"2011","journal-title":"J\u00a0Pharm Sci"},{"key":"10.1016\/j.xphs.2019.11.010_bib9","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1016\/j.ijpharm.2015.04.014","article-title":"A\u00a0micelle-like structure of poloxamer-methotrexate conjugates as nanocarrier for methotrexate delivery","volume":"487","author":"Ren","year":"2015","journal-title":"Int J Pharm"},{"key":"10.1016\/j.xphs.2019.11.010_bib10","doi-asserted-by":"crossref","first-page":"379","DOI":"10.3390\/ma8020379","article-title":"Preparation of pH sensitive pluronic-docetaxel conjugate micelles to balance the stability and controlled release issues","volume":"8","author":"Liang","year":"2015","journal-title":"Materials (Basel)"},{"key":"10.1016\/j.xphs.2019.11.010_bib11","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.cis.2014.10.010","article-title":"Fluorescence emission of pyrene in surfactant solutions","volume":"215","author":"Pi\u00f1eiro","year":"2015","journal-title":"Adv Colloid Interface Sci"},{"key":"10.1016\/j.xphs.2019.11.010_bib12","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1038\/sj.jidsymp.5650037","article-title":"Mechanisms of action of etanercept in psoriasis","volume":"12","author":"Tan","year":"2007","journal-title":"J\u00a0Investig Dermatol Symp Proc"},{"key":"10.1016\/j.xphs.2019.11.010_bib13","doi-asserted-by":"crossref","first-page":"249367","DOI":"10.1155\/2014\/249367","article-title":"Effect of gloriosa superba and catharanthus roseus extracts on IFN-gamma-induced keratin 17 expression in HaCaT human keratinocytes","volume":"2014","author":"Pattarachotanant","year":"2014","journal-title":"Evid Based Complement Alternat Med"},{"key":"10.1016\/j.xphs.2019.11.010_bib14","doi-asserted-by":"crossref","first-page":"4445","DOI":"10.1021\/acs.molpharmaceut.5b00639","article-title":"Synthesis and characterization of a novel mycophenolic acid-quinic acid conjugate serving as immunosuppressant with decreased toxicity","volume":"12","author":"Peng","year":"2015","journal-title":"Mol Pharm"},{"key":"10.1016\/j.xphs.2019.11.010_bib15","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1016\/S0927-7765(99)00072-7","article-title":"Micelle-like structures of poly(ethylene oxide)-block-poly(2-hydroxyethyl aspartamide)-methotrexate conjugates","volume":"16","author":"Li","year":"1999","journal-title":"Colloids Surf B Biointerfaces"},{"key":"10.1016\/j.xphs.2019.11.010_bib16","doi-asserted-by":"crossref","first-page":"1752","DOI":"10.1016\/j.actbio.2008.04.021","article-title":"Synthesis of novel biodegradable and self-assembling methoxy poly(ethylene glycol)-palmitate nanocarrier for curcumin delivery to cancer cells","volume":"4","author":"Sahu","year":"2008","journal-title":"Acta Biomater"},{"key":"10.1016\/j.xphs.2019.11.010_bib17","doi-asserted-by":"crossref","first-page":"2569","DOI":"10.1007\/s11095-010-0233-4","article-title":"Polymeric micelles in anticancer therapy: targeting, imaging and triggered release","volume":"27","author":"Oerlemans","year":"2010","journal-title":"Pharm Res"},{"key":"10.1016\/j.xphs.2019.11.010_bib18","series-title":"An Introduction to Aspects of Thermodynamics and Kinetics Relevant to Materials Science","first-page":"425","article-title":"Chapter XIV\u2013thermodynamics of micelles","author":"Machlin","year":"2007"},{"key":"10.1016\/j.xphs.2019.11.010_bib19","doi-asserted-by":"crossref","first-page":"11","DOI":"10.3390\/jfb9010011","article-title":"Formulation of poloxamers for drug delivery","volume":"9","author":"Bodratti","year":"2018","journal-title":"J\u00a0Funct Biomater"},{"key":"10.1016\/j.xphs.2019.11.010_bib20","doi-asserted-by":"crossref","first-page":"2023","DOI":"10.1021\/bc8002315","article-title":"Different internalization pathways of polymeric micelles and unimers and their effects on vesicular transport","volume":"19","author":"Sahay","year":"2008","journal-title":"Bioconjug Chem"}],"container-title":["Journal of Pharmaceutical Sciences"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022354919307531?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022354919307531?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,20]],"date-time":"2025-09-20T09:27:23Z","timestamp":1758360443000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0022354919307531"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,2]]},"references-count":20,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2020,2]]}},"alternative-id":["S0022354919307531"],"URL":"https:\/\/doi.org\/10.1016\/j.xphs.2019.11.010","relation":{},"ISSN":["0022-3549"],"issn-type":[{"value":"0022-3549","type":"print"}],"subject":[],"published":{"date-parts":[[2020,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Enhanced Antipsoriatic Activity of Mycophenolic Acid Against the TNF-\u03b1-Induced HaCaT Cell Proliferation by Conjugated Poloxamer Micelles","name":"articletitle","label":"Article Title"},{"value":"Journal of Pharmaceutical Sciences","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.xphs.2019.11.010","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2020 American Pharmacists Association\u00ae. Published by Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}