{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,24]],"date-time":"2026-06-24T10:20:02Z","timestamp":1782296402930,"version":"3.54.5"},"reference-count":14,"publisher":"Elsevier BV","issue":"12","license":[{"start":{"date-parts":[[2024,12,1]],"date-time":"2024-12-01T00:00:00Z","timestamp":1733011200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,12,1]],"date-time":"2024-12-01T00:00:00Z","timestamp":1733011200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,10,11]],"date-time":"2024-10-11T00:00:00Z","timestamp":1728604800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["jpharmsci.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Pharmaceutical Sciences"],"published-print":{"date-parts":[[2024,12]]},"DOI":"10.1016\/j.xphs.2024.10.003","type":"journal-article","created":{"date-parts":[[2024,10,18]],"date-time":"2024-10-18T17:52:51Z","timestamp":1729273971000},"page":"3538-3542","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":1,"title":["Physical compatibility and chemical stability of bupivacaine, epinephrine, and nalbuphine in 0.45 % sodium chloride, 0.9 % sodium chloride, or plasma-lyte A"],"prefix":"10.1016","volume":"113","author":[{"given":"Zachary","family":"Senger","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gladys Uwera","family":"Mihigo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7595-4410","authenticated-orcid":false,"given":"Mitchell S.","family":"Howard","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2959-7619","authenticated-orcid":false,"given":"Gabriella","family":"Baki","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mariann D.","family":"Churchwell","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Virender","family":"Kumar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0321-5608","authenticated-orcid":false,"given":"Justin P.","family":"Reinert","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.xphs.2024.10.003_bib0001","doi-asserted-by":"crossref","first-page":"114","DOI":"10.1016\/j.jss.2022.10.052","article-title":"Implementation of multimodal pain protocol associated with opioid use reduction in trauma patients","volume":"284","author":"Sparks-Joplin","year":"2023","journal-title":"J Surg Res"},{"key":"10.1016\/j.xphs.2024.10.003_bib0002","doi-asserted-by":"crossref","first-page":"3461","DOI":"10.2147\/JPR.S238772","article-title":"A commonsense patient-centered approach to multimodal analgesia within surgical enhanced recovery protocols","volume":"12","author":"Mariano","year":"2019","journal-title":"J Pain Res"},{"issue":"6","key":"10.1016\/j.xphs.2024.10.003_bib0003","first-page":"223","article-title":"Dexmedetomidine as an adjunctive analgaesic in the perioperative setting: a review of the literature","volume":"31","author":"Reinert","year":"2021","journal-title":"J Perioper Pract"},{"issue":"5","key":"10.1016\/j.xphs.2024.10.003_bib0004","doi-asserted-by":"crossref","first-page":"891","DOI":"10.1097\/ALN.0000000000002132","article-title":"Association of multimodal pain management strategies with perioperative outcomes and resource utilization","volume":"128","author":"Memtsoudis","year":"2018","journal-title":"Anesthesiology"},{"issue":"4","key":"10.1016\/j.xphs.2024.10.003_bib0005","doi-asserted-by":"crossref","first-page":"202","DOI":"10.1177\/87551225211004145","article-title":"Efficacy and safety considerations with second-generation antipsychotics as adjunctive analgesics: a review of literature","volume":"37","author":"Coronado","year":"2021","journal-title":"J Pharmacy Technol"},{"key":"10.1016\/j.xphs.2024.10.003_bib0006","doi-asserted-by":"crossref","first-page":"264","DOI":"10.1016\/j.jss.2019.10.014","article-title":"Statewide utilization of multimodal analgesia and length of stay after colectomy","volume":"247","author":"De Roo","year":"2020","journal-title":"J Surgical Res"},{"key":"10.1016\/j.xphs.2024.10.003_bib0007","doi-asserted-by":"crossref","first-page":"227","DOI":"10.2147\/JPR.S152230","article-title":"Effect of bupivacaine and adjuvant drugs for regional anesthesia on nerve tissue oximetry and nerve blood flow","volume":"11","author":"Wiesmann","year":"2018","journal-title":"J Pain Res"},{"issue":"5","key":"10.1016\/j.xphs.2024.10.003_bib0008","doi-asserted-by":"crossref","first-page":"757","DOI":"10.1097\/00000542-198911000-00021","article-title":"Effects of local anesthesia on nerve blood flow: studies using lidocaine with and without epinephrine","volume":"71","author":"Myers","year":"1989","journal-title":"Anesthesiology"},{"issue":"2","key":"10.1016\/j.xphs.2024.10.003_bib0009","doi-asserted-by":"crossref","first-page":"326","DOI":"10.4103\/0259-1162.194590","article-title":"Randomized controlled trial for evaluating the analgesic effect of nalbuphine as an adjuvant to bupivacaine in supraclavicular block under ultrasound guidance","volume":"11","author":"Nazir","year":"2017","journal-title":"Anesth Essays Res"},{"key":"10.1016\/j.xphs.2024.10.003_bib0010","series-title":"Trissel's Stability of Compounded Formulations","author":"Trissel","year":"2009"},{"issue":"6","key":"10.1016\/j.xphs.2024.10.003_bib0011","first-page":"522","article-title":"Intravenous physical compatibility of heparin sodium and furosemide","volume":"26","author":"Maktabi","year":"2022","journal-title":"Int J Pharm Compd"},{"key":"10.1016\/j.xphs.2024.10.003_bib0012","doi-asserted-by":"crossref","DOI":"10.1136\/ejhpharm-2024-004128","article-title":"Physical compatibility of ceftriaxone and cefepime in 0.45% sodium chloride, Ringer's lactate solution, and Plasma-Lyte A","author":"Kelley","year":"2024","journal-title":"Eur J Hospital Pharmacy"},{"key":"10.1016\/j.xphs.2024.10.003_bib0013","doi-asserted-by":"crossref","DOI":"10.1177\/00185787241279375","article-title":"Evaluation of the physical compatibility of intravenous methocarbamol in lactated Ringer's, 0.45% normal saline, and plasma-lyte A","author":"Twardzik","year":"2024","journal-title":"Hosp Pharm"},{"issue":"1","key":"10.1016\/j.xphs.2024.10.003_bib0014","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1016\/j.ajps.2016.08.002","article-title":"Development of RP-HPLC method for simultaneous determination of docetaxel and curcumin in rat plasma: validation and stability","volume":"12","author":"Kim","year":"2017","journal-title":"Asian J Pharm Sci"}],"container-title":["Journal of Pharmaceutical Sciences"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022354924004362?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022354924004362?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,12,13]],"date-time":"2024-12-13T10:01:16Z","timestamp":1734084076000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0022354924004362"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,12]]},"references-count":14,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2024,12]]}},"alternative-id":["S0022354924004362"],"URL":"https:\/\/doi.org\/10.1016\/j.xphs.2024.10.003","relation":{},"ISSN":["0022-3549"],"issn-type":[{"value":"0022-3549","type":"print"}],"subject":[],"published":{"date-parts":[[2024,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Physical compatibility and chemical stability of bupivacaine, epinephrine, and nalbuphine in 0.45 % sodium chloride, 0.9 % sodium chloride, or plasma-lyte A","name":"articletitle","label":"Article Title"},{"value":"Journal of Pharmaceutical Sciences","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.xphs.2024.10.003","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 The Authors. Published by Elsevier Inc. on behalf of American Pharmacists Association.","name":"copyright","label":"Copyright"}]}}