{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T23:44:28Z","timestamp":1792021468768,"version":"4.4.0"},"reference-count":67,"publisher":"Elsevier BV","issue":"12","license":[{"start":{"date-parts":[[2026,12,1]],"date-time":"2026-12-01T00:00:00Z","timestamp":1796083200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,12,1]],"date-time":"2026-12-01T00:00:00Z","timestamp":1796083200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["jpharmsci.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Pharmaceutical Sciences"],"published-print":{"date-parts":[[2026,12]]},"DOI":"10.1016\/j.xphs.2026.104518","type":"journal-article","created":{"date-parts":[[2026,9,26]],"date-time":"2026-09-26T15:24:10Z","timestamp":1790436250000},"page":"104518","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"title":["Tuning surface chemistry via cocrystallization improves wettability of a hydrophobic flavonoid"],"prefix":"10.1016","volume":"115","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5392-7331","authenticated-orcid":false,"given":"Sanika","family":"Jadhav","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2936-0926","authenticated-orcid":false,"given":"Lewis L.","family":"Stevens","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"1","key":"10.1016\/j.xphs.2026.104518_bib0001","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1016\/0378-5173(86)90148-1","article-title":"Correlation between wettability and dissolution rate of pharmaceutical powders","volume":"28","author":"Lippold","year":"1986","journal-title":"Int J Pharm"},{"issue":"2","key":"10.1016\/j.xphs.2026.104518_bib0002","doi-asserted-by":"crossref","first-page":"319","DOI":"10.1016\/0040-6031(89)87268-5","article-title":"Structure-activity relationships for solubility and wettability of a number of substituted barbituric acids","volume":"138","author":"Buckton","year":"1989","journal-title":"Thermochim Acta"},{"issue":"1\u20132","key":"10.1016\/j.xphs.2026.104518_bib0003","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1016\/0378-5173(95)04060-9","article-title":"Assessment of wettability and its relationship to the intrinsic dissolution rate of doped phenytoin crystals","volume":"126","author":"Chow","year":"1995","journal-title":"Int J Pharm"},{"issue":"1","key":"10.1016\/j.xphs.2026.104518_bib0004","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1016\/j.xphs.2024.09.020","article-title":"The importance of surface composition and wettability on the dissolution performance of high drug loading amorphous dispersion formulations","volume":"114","author":"Hiew","year":"2025","journal-title":"J Pharm Sci"},{"key":"10.1016\/j.xphs.2026.104518_bib0005","doi-asserted-by":"crossref","DOI":"10.1016\/j.ijpharm.2024.125025","article-title":"Impact of route of particle engineering on dissolution performance of posaconazole","volume":"669","author":"Xiang","year":"2025","journal-title":"Int J Pharm"},{"issue":"7","key":"10.1016\/j.xphs.2026.104518_bib0006","doi-asserted-by":"crossref","first-page":"2824","DOI":"10.1021\/cg400140a","article-title":"Impact of crystal habit on biopharmaceutical performance of celecoxib","volume":"13","author":"Modi","year":"2013","journal-title":"Cryst Growth Des"},{"issue":"2","key":"10.1016\/j.xphs.2026.104518_bib0007","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1016\/S0378-5173(98)00020-9","article-title":"Surface treatment of the hydrophobic drug danazol to improve drug dissolution","volume":"165","author":"Brown","year":"1998","journal-title":"Int J Pharm"},{"issue":"2","key":"10.1016\/j.xphs.2026.104518_bib0008","doi-asserted-by":"crossref","first-page":"478","DOI":"10.1016\/j.ejpb.2008.05.026","article-title":"Surface composition and contact angle relationships for differently prepared solid dispersions","volume":"70","author":"Dahlberg","year":"2008","journal-title":"Eur J Pharm Biopharm"},{"issue":"1\u20132","key":"10.1016\/j.xphs.2026.104518_bib0009","doi-asserted-by":"crossref","first-page":"351","DOI":"10.1016\/j.ijpharm.2014.09.002","article-title":"Influence of surface modification on wettability and surface energy characteristics of pharmaceutical excipient powders","volume":"475","author":"Karde","year":"2014","journal-title":"Int J Pharm"},{"issue":"1","key":"10.1016\/j.xphs.2026.104518_bib0010","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1016\/j.ijpharm.2017.09.062","article-title":"Improving the wetting and dissolution of ibuprofen using solventless co-milling","volume":"533","author":"Varghese","year":"2017","journal-title":"Int J Pharm"},{"key":"10.1016\/j.xphs.2026.104518_bib0011","doi-asserted-by":"crossref","DOI":"10.1016\/j.ijpharm.2021.120853","article-title":"Impact of altered hydrophobicity and reduced agglomeration on dissolution of micronized poorly water-soluble drug powders after dry coating","volume":"606","author":"Kim","year":"2021","journal-title":"Int J Pharm"},{"issue":"2","key":"10.1016\/j.xphs.2026.104518_bib0012","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1016\/0378-5173(91)90054-R","article-title":"Surface analysis of pharmaceutical powders: x-ray photoelectron spectroscopy (XPS) related to powder wettability","volume":"72","author":"Buckton","year":"1991","journal-title":"Int J Pharm"},{"issue":"2","key":"10.1016\/j.xphs.2026.104518_bib0013","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1016\/S0378-5173(00)00341-0","article-title":"Wettability studies of morphine sulfate powders","volume":"198","author":"Prestidge","year":"2000","journal-title":"Int J Pharm"},{"issue":"2","key":"10.1016\/j.xphs.2026.104518_bib0014","doi-asserted-by":"crossref","first-page":"84","DOI":"10.1016\/j.ejps.2010.03.003","article-title":"Wettability and surface chemistry of crystalline and amorphous forms of a poorly water soluble drug","volume":"40","author":"Puri","year":"2010","journal-title":"Eur J Pharm Sci"},{"issue":"7","key":"10.1016\/j.xphs.2026.104518_bib0015","doi-asserted-by":"crossref","first-page":"1844","DOI":"10.1016\/j.xphs.2024.02.001","article-title":"Effect of differential surface anisotropy on dissolution behavior of fenofibrate crystal habits: comparative study using USP type 2 and type 4 dissolution apparatuses","volume":"113","author":"Shah","year":"2024","journal-title":"J Pharm Sci"},{"issue":"6","key":"10.1016\/j.xphs.2026.104518_bib0016","doi-asserted-by":"crossref","first-page":"2760","DOI":"10.1021\/la0532407","article-title":"Anisotropic surface energetics and wettability of macroscopic form I paracetamol crystals","volume":"22","author":"Heng","year":"2006","journal-title":"Langmuir"},{"issue":"4","key":"10.1016\/j.xphs.2026.104518_bib0017","doi-asserted-by":"crossref","first-page":"E12","DOI":"10.1208\/pt070484","article-title":"Anisotropic surface chemistry of crystalline pharmaceutical solids","volume":"7","author":"Heng","year":"2006","journal-title":"AAPS PharmSciTech"},{"issue":"16","key":"10.1016\/j.xphs.2026.104518_bib0018","doi-asserted-by":"crossref","first-page":"6905","DOI":"10.1021\/la060596p","article-title":"Wettability of paracetamol polymorphic forms I and II","volume":"22","author":"Heng","year":"2006","journal-title":"Langmuir"},{"issue":"7","key":"10.1016\/j.xphs.2026.104518_bib0019","doi-asserted-by":"crossref","first-page":"883","DOI":"10.3390\/pharmaceutics16070883","article-title":"Process-induced crystal surface anisotropy and the impact on the powder properties of odanacatib","volume":"16","author":"Bade","year":"2024","journal-title":"Pharmaceutics"},{"issue":"15","key":"10.1016\/j.xphs.2026.104518_bib0020","doi-asserted-by":"crossref","first-page":"5593","DOI":"10.1021\/acs.chemmater.5c00634","article-title":"A combined experimental and modeling workflow to tune surface properties of organic materials via cocrystallization","volume":"37","author":"Parisi","year":"2025","journal-title":"Chem Mater"},{"issue":"34","key":"10.1016\/j.xphs.2026.104518_bib0021","first-page":"36389","article-title":"Cocrystal of lutein with improved stability and bioavailability","volume":"9","author":"Zheng","year":"2024","journal-title":"ACS Omega"},{"issue":"4","key":"10.1016\/j.xphs.2026.104518_bib0022","doi-asserted-by":"crossref","first-page":"1161","DOI":"10.3390\/pharmaceutics15041161","article-title":"Cocrystals by design: a rational coformer selection approach for tackling the API problems","volume":"15","author":"Singh","year":"2023","journal-title":"Pharmaceutics"},{"issue":"4","key":"10.1016\/j.xphs.2026.104518_bib0023","doi-asserted-by":"crossref","first-page":"640","DOI":"10.1039\/C5CC08216A","article-title":"Pharmaceutical cocrystals: along the path to improved medicines","volume":"52","author":"Duggirala","year":"2016","journal-title":"Chem Commun"},{"issue":"3","key":"10.1016\/j.xphs.2026.104518_bib0024","doi-asserted-by":"crossref","first-page":"108","DOI":"10.3390\/pharmaceutics10030108","article-title":"Engineering cocrystals of poorly water-soluble drugs to enhance dissolution in aqueous medium","volume":"10","author":"Sathisaran","year":"2018","journal-title":"Pharmaceutics"},{"key":"10.1016\/j.xphs.2026.104518_bib0025","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1016\/j.addr.2017.03.003","article-title":"Pharmaceutical cocrystals, salts and multicomponent systems; intermolecular interactions and property based design","volume":"117","author":"Berry","year":"2017","journal-title":"Adv Drug Deliv Rev"},{"issue":"9","key":"10.1016\/j.xphs.2026.104518_bib0026","doi-asserted-by":"crossref","first-page":"3153","DOI":"10.1021\/acs.cgd.5c00222","article-title":"Engineering cocrystals of Naringenin: new solid forms and assessing predictive tools for coformer selection","volume":"25","author":"Jadhav","year":"2025","journal-title":"Cryst Growth Des"},{"issue":"12","key":"10.1016\/j.xphs.2026.104518_bib0027","doi-asserted-by":"crossref","first-page":"2847","DOI":"10.1007\/s11095-023-03562-5","article-title":"Coformer-dependent physical stability in a series of naringenin-based coamorphous materials with caffeine, theophylline, and theobromine: jadhav, Bahl and Stevens","volume":"40","author":"Jadhav","year":"2023","journal-title":"Pharm Res"},{"issue":"3","key":"10.1016\/j.xphs.2026.104518_bib67","doi-asserted-by":"crossref","first-page":"932","DOI":"10.1021\/je501004g","article-title":"Solubilities of naringin and naringenin in different solvents and dissociation constants of naringenin","volume":"60","author":"Zhang","year":"2015","journal-title":"J Chem Eng Data"},{"issue":"1","key":"10.1016\/j.xphs.2026.104518_bib0028","doi-asserted-by":"crossref","first-page":"226","DOI":"10.1107\/S1600576719014092","article-title":"Mercury 4.0: from visualization to analysis, design and prediction","volume":"53","author":"Macrae","year":"2020","journal-title":"J Appl Crystallogr"},{"issue":"22","key":"10.1016\/j.xphs.2026.104518_bib0029","doi-asserted-by":"crossref","first-page":"3025","DOI":"10.1039\/C8CE00341F","article-title":"Pharmaceutical cocrystals of naringenin with improved dissolution performance","volume":"20","author":"Luo","year":"2018","journal-title":"CrystEngComm"},{"issue":"10","key":"10.1016\/j.xphs.2026.104518_bib0030","doi-asserted-by":"crossref","first-page":"4160","DOI":"10.1021\/acs.cgd.4c00259","article-title":"Surface analysis\u2013 from crystal structures to particle properties","volume":"24","author":"Moldovan","year":"2024","journal-title":"Cryst Growth Des"},{"key":"10.1016\/j.xphs.2026.104518_bib0031","doi-asserted-by":"crossref","DOI":"10.1016\/j.apsadv.2021.100112","article-title":"Systematic and collaborative approach to problem solving using X-ray photoelectron spectroscopy","volume":"5","author":"Fairley","year":"2021","journal-title":"Appl Surf Sci Adv"},{"issue":"6","key":"10.1016\/j.xphs.2026.104518_bib0032","first-page":"38","article-title":"Practical guide for curve fitting in x-ray photoelectron spectroscopy","author":"Major","year":"2020","journal-title":"J Vac Sci Technol A"},{"issue":"1","key":"10.1016\/j.xphs.2026.104518_bib0033","first-page":"23","article-title":"Development of the NIST X-ray photoelectron spectroscopy (XPS) database, version 5","author":"Lee","year":"2024","journal-title":"Data Sci J"},{"key":"10.1016\/j.xphs.2026.104518_bib0034","unstructured":"ThermoFisher. Interpretation of C XPS spectra. https:\/\/www.thermofisher.com\/us\/en\/home\/materials-science\/learning-center\/periodic-table\/non-metal\/carbon.html"},{"key":"10.1016\/j.xphs.2026.104518_bib0035","first-page":"25","volume":"40","author":"Chastain","year":"1992"},{"issue":"4","key":"10.1016\/j.xphs.2026.104518_bib0036","doi-asserted-by":"crossref","first-page":"598","DOI":"10.1016\/j.clay.2011.05.009","article-title":"Spectroscopic and chromatographic analysis of yellow flavonoidic lakes: quercetin chromophore","volume":"53","author":"Bourhis","year":"2011","journal-title":"Appl Clay Sci"},{"issue":"2","key":"10.1016\/j.xphs.2026.104518_bib0037","doi-asserted-by":"crossref","first-page":"385","DOI":"10.1016\/0021-9797(90)90148-H","article-title":"XPS analysis of model p-aramid compounds and poly (p-phenylene terephthalamide) fibers","volume":"134","author":"Chappell","year":"1990","journal-title":"J Colloid Interface Sci"},{"issue":"1","key":"10.1016\/j.xphs.2026.104518_bib0038","first-page":"39","article-title":"Practical guides for x-ray photoelectron spectroscopy (XPS): interpreting the carbon 1s spectrum","author":"Gengenbach","year":"2021","journal-title":"J Vac Sci Technol A"},{"issue":"9","key":"10.1016\/j.xphs.2026.104518_bib0039","doi-asserted-by":"crossref","first-page":"3153","DOI":"10.1021\/acs.cgd.5c00222","article-title":"Engineering cocrystals of Naringenin: new solid forms and assessing predictive tools for coformer selection","volume":"25","author":"Jadhav","year":"2025","journal-title":"Cryst Growth Des"},{"issue":"1\u20133","key":"10.1016\/j.xphs.2026.104518_bib0040","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/0378-5173(88)90093-2","article-title":"The assessment, and pharmaceutical importance, of the solid\/liquid and the solid\/vapour interface: a review with respect to powders","volume":"44","author":"Buckton","year":"1988","journal-title":"Int J Pharm"},{"issue":"1\u20133","key":"10.1016\/j.xphs.2026.104518_bib0041","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/0378-5173(88)90093-2","article-title":"The assessment, and pharmaceutical importance, of the solid\/liquid and the solid\/vapour interface: a review with respect to powders","volume":"44","author":"Buckton","year":"1988","journal-title":"Int J Pharm"},{"issue":"8","key":"10.1016\/j.xphs.2026.104518_bib0042","doi-asserted-by":"crossref","first-page":"988","DOI":"10.1021\/ie50320a024","article-title":"Resistance of solid surfaces to wetting by water","volume":"28","author":"Wenzel","year":"1936","journal-title":"Ind Eng Chem"},{"key":"10.1016\/j.xphs.2026.104518_bib0043","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1146\/annurev.matsci.38.060407.132434","article-title":"Wetting and roughness","volume":"38","author":"Qu\u00e9r\u00e9","year":"2008","journal-title":"Annu Rev Mater Res"},{"issue":"2\u20133","key":"10.1016\/j.xphs.2026.104518_bib0044","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1016\/0032-5910(86)80027-4","article-title":"Assessment of the wettability of powders by use of compressed powder discs","volume":"46","author":"Buckton","year":"1986","journal-title":"Powder Technol"},{"issue":"1\u20132","key":"10.1016\/j.xphs.2026.104518_bib0045","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1016\/S0378-5173(01)00949-8","article-title":"Application of time-dependent sessile drop contact angles on compacts to characterise the surface energetics of sulfathiazole crystals","volume":"234","author":"Muster","year":"2002","journal-title":"Int J Pharm"},{"issue":"3","key":"10.1016\/j.xphs.2026.104518_bib0046","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1016\/0378-5173(88)90199-8","article-title":"Surface energetics of powders before and after compaction","volume":"41","author":"Luangtana-anan","year":"1988","journal-title":"Int J Pharm"},{"issue":"1\u20132","key":"10.1016\/j.xphs.2026.104518_bib0047","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1016\/j.ijpharm.2015.12.022","article-title":"Investigation of surface porosity measurements and compaction pressure as means to ensure consistent contact angle determinations","volume":"498","author":"Holm","year":"2016","journal-title":"Int J Pharm"},{"key":"10.1016\/j.xphs.2026.104518_bib0048","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1002\/9781119323716.ch2","article-title":"Wettability of powders. Adhesion in pharmaceutical","author":"Chibowski","year":"2017","journal-title":"Biomedical and Dental Fields"},{"issue":"3","key":"10.1016\/j.xphs.2026.104518_bib0049","doi-asserted-by":"crossref","first-page":"817","DOI":"10.1063\/1.555688","article-title":"International tables of the surface tension of water","volume":"12","author":"Vargaftik","year":"1983","journal-title":"J Phys Chem Ref Data"},{"issue":"16","key":"10.1016\/j.xphs.2026.104518_bib0050","doi-asserted-by":"crossref","first-page":"4595","DOI":"10.5194\/acp-8-4595-2008","article-title":"Ternary solution of sodium chloride, succinic acid and water; surface tension and its influence on cloud droplet activation","volume":"8","author":"Vanhanen","year":"2008","journal-title":"Atmos Chem Phys"},{"issue":"3","key":"10.1016\/j.xphs.2026.104518_bib0051","doi-asserted-by":"crossref","first-page":"277","DOI":"10.1029\/95GL03810","article-title":"Dissolution behavior and surface tension effects of organic compounds in nucleating cloud droplets","volume":"23","author":"Shulman","year":"1996","journal-title":"Geophys Res Lett"},{"issue":"1","key":"10.1016\/j.xphs.2026.104518_bib0052","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1021\/je050366x","article-title":"Surface tensions and densities of oxalic, malonic, succinic, maleic, malic, and cis-pinonic acids","volume":"51","author":"Hyv\u00e4rinen","year":"2006","journal-title":"J Chem Eng Data"},{"key":"10.1016\/j.xphs.2026.104518_bib0053","doi-asserted-by":"crossref","first-page":"94","DOI":"10.1016\/j.jaerosci.2013.06.004","article-title":"Surface tension of solutions containing dicarboxylic acids with ammonium sulfate, d-glucose, or humic acid","volume":"64","author":"Lee","year":"2013","journal-title":"J Aerosol Sci"},{"issue":"16","key":"10.1016\/j.xphs.2026.104518_bib0054","doi-asserted-by":"crossref","first-page":"11055","DOI":"10.1039\/D3CP00322A","article-title":"Surface tension models for binary aqueous solutions: a review and intercomparison","volume":"25","author":"Kleinheins","year":"2023","journal-title":"Phys Chem Chem Phys"},{"issue":"3","key":"10.1016\/j.xphs.2026.104518_bib0055","doi-asserted-by":"crossref","first-page":"1435","DOI":"10.1021\/cg901481q","article-title":"Characterization of proton transfer in co-crystals by X-ray photoelectron spectroscopy (XPS)","volume":"10","author":"Stevens","year":"2010","journal-title":"Cryst Growth Des"},{"issue":"11","key":"10.1016\/j.xphs.2026.104518_bib0056","doi-asserted-by":"crossref","first-page":"4453","DOI":"10.1002\/jps.22164","article-title":"Salt or co-crystal? Determination of protonation state by X-ray photoelectron spectroscopy (XPS)","volume":"99","author":"Stevens","year":"2010","journal-title":"J Pharm Sci"},{"issue":"2","key":"10.1016\/j.xphs.2026.104518_bib0057","doi-asserted-by":"crossref","first-page":"654","DOI":"10.1021\/acs.molpharmaceut.1c00786","article-title":"Surface enrichment of surfactants in amorphous drugs: an X-ray photoelectron spectroscopy study","volume":"19","author":"Yu","year":"2022","journal-title":"Mol Pharm"},{"issue":"5","key":"10.1016\/j.xphs.2026.104518_bib0058","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1002\/sia.740030506","article-title":"Empirical atomic sensitivity factors for quantitative analysis by electron spectroscopy for chemical analysis","volume":"3","author":"Wagner","year":"1981","journal-title":"Surf Interface Anal"},{"issue":"1","key":"10.1016\/j.xphs.2026.104518_bib0059","doi-asserted-by":"crossref","first-page":"126","DOI":"10.1023\/A:1018900431661","article-title":"Surface characterization of activated charcoal by X-ray photoelectron spectroscopy (XPS): correlation with phenobarbital adsorption data","volume":"9","author":"Burke","year":"1992","journal-title":"Pharm Res"},{"issue":"1","key":"10.1016\/j.xphs.2026.104518_bib0060","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1002\/sia.740010103","article-title":"Quantitative electron spectroscopy of surfaces: a standard data base for electron inelastic mean free paths in solids","volume":"1","author":"Seah","year":"1979","journal-title":"Surf Interface Anal"},{"issue":"11","key":"10.1016\/j.xphs.2026.104518_bib0061","doi-asserted-by":"crossref","first-page":"6332","DOI":"10.1021\/acs.cgd.1c00807","article-title":"Proton transfer on the edge of the salt\/cocrystal continuum: x-ray photoelectron spectroscopy of three isonicotinamide salts","volume":"21","author":"Edwards","year":"2021","journal-title":"Cryst Growth Des"},{"key":"10.1016\/j.xphs.2026.104518_bib0062","unstructured":"XPS. What is Adventitious Carbon? https:\/\/www.xpsfitting.com\/2011\/01\/what-is-adventitious-carbon.html"},{"issue":"10","key":"10.1016\/j.xphs.2026.104518_bib0063","doi-asserted-by":"crossref","DOI":"10.1107\/S0108270198099314","article-title":"2-pyridinecarboxylic acid","volume":"54","author":"Hamazaki","year":"1998","journal-title":"Acta Crystallogr Sect C: Cryst Struct Commun"},{"issue":"7","key":"10.1016\/j.xphs.2026.104518_bib0064","doi-asserted-by":"crossref","first-page":"2980","DOI":"10.1021\/acs.molpharmaceut.9b00227","article-title":"Molecular basis of water sorption behavior of rivaroxaban-malonic acid cocrystal","volume":"16","author":"Kale","year":"2019","journal-title":"Mol Pharm"},{"issue":"4","key":"10.1016\/j.xphs.2026.104518_bib0065","doi-asserted-by":"crossref","first-page":"861","DOI":"10.1002\/jps.20296","article-title":"Water adsorption kinetics and contact angles of pharmaceutical powders","volume":"94","author":"Muster","year":"2005","journal-title":"J Pharm Sci"},{"issue":"2","key":"10.1016\/j.xphs.2026.104518_bib0066","doi-asserted-by":"crossref","first-page":"216","DOI":"10.1016\/j.ijpharm.2005.10.006","article-title":"Interactions of water with the surfaces of crystal polymorphs","volume":"307","author":"Carvajal","year":"2006","journal-title":"Int J Pharm"}],"container-title":["Journal of Pharmaceutical Sciences"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022354926003680?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022354926003680?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T22:46:28Z","timestamp":1792017988000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0022354926003680"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,12]]},"references-count":67,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2026,12]]}},"alternative-id":["S0022354926003680"],"URL":"https:\/\/doi.org\/10.1016\/j.xphs.2026.104518","relation":{},"ISSN":["0022-3549"],"issn-type":[{"value":"0022-3549","type":"print"}],"subject":[],"published":{"date-parts":[[2026,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Tuning surface chemistry via cocrystallization improves wettability of a hydrophobic flavonoid","name":"articletitle","label":"Article Title"},{"value":"Journal of Pharmaceutical Sciences","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.xphs.2026.104518","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 American Pharmacists Association\u00ae. Published by Elsevier Inc. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"104518"}}