{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,21]],"date-time":"2026-10-21T18:38:06Z","timestamp":1792607886634,"version":"4.5.0"},"reference-count":5,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2022,12,1]],"date-time":"2022-12-01T00:00:00Z","timestamp":1669852800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,12,1]],"date-time":"2022-12-01T00:00:00Z","timestamp":1669852800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2022,9,30]],"date-time":"2022-09-30T00:00:00Z","timestamp":1664496000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["cell.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["STAR Protocols"],"published-print":{"date-parts":[[2022,12]]},"DOI":"10.1016\/j.xpro.2022.101803","type":"journal-article","created":{"date-parts":[[2022,11,4]],"date-time":"2022-11-04T01:10:08Z","timestamp":1667524208000},"page":"101803","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":17,"title":["An improved protocol for generation and characterization of human-induced pluripotent stem cell-derived retinal pigment epithelium cells"],"prefix":"10.1016","volume":"3","author":[{"given":"Harshini","family":"Surendran","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lalitha","family":"Soundararajan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vijay Bhaskar","family":"Reddy K","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Janavi","family":"Subramani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jonathan","family":"Stoddard","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rene","family":"Reynaga","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wayne","family":"Tschetter","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Renee C.","family":"Ryals","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rajarshi","family":"Pal","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.xpro.2022.101803_bib1","doi-asserted-by":"crossref","first-page":"647","DOI":"10.1016\/j.stemcr.2015.08.015","article-title":"cGMP-manufactured human induced pluripotent stem cells are available for pre-clinical and clinical applications","volume":"5","author":"Baghbaderani","year":"2015","journal-title":"Stem Cell Rep."},{"key":"10.1016\/j.xpro.2022.101803_bib2","doi-asserted-by":"crossref","first-page":"101757","DOI":"10.1016\/j.scr.2020.101757","article-title":"Derivation of three induced pluripotent stem cell lines under feeder-free culture conditions from peripheral blood mononuclear cells (PBMC) of Indian patients suffering from inherited retinal diseases carrying different mutations","volume":"45","author":"Konala","year":"2020","journal-title":"Stem Cell Res."},{"key":"10.1016\/j.xpro.2022.101803_bib3","doi-asserted-by":"crossref","first-page":"70","DOI":"10.1186\/s13287-021-02134-x","article-title":"Transplantation of retinal pigment epithelium and photoreceptors generated concomitantly via small molecule-mediated differentiation rescues visual function in rodent models of retinal degeneration","volume":"12","author":"Surendran","year":"2021","journal-title":"Stem Cell Res. Ther."},{"key":"10.1016\/j.xpro.2022.101803_bib4","doi-asserted-by":"crossref","first-page":"283","DOI":"10.1007\/7651_2018_140","article-title":"Generation of transplantable retinal pigmented epithelial (RPE) cells for treatment of age-related macular degeneration (AMD)","volume":"2045","author":"Surendran","year":"2019","journal-title":"Methods Mol. Biol."},{"key":"10.1016\/j.xpro.2022.101803_bib5","doi-asserted-by":"crossref","first-page":"2162","DOI":"10.1097\/IAE.0000000000001462","article-title":"Subretinal cell-based therapy: an analysis of surgical variables to increase cell survival","volume":"37","author":"Wilson","year":"2017","journal-title":"Retina"}],"container-title":["STAR Protocols"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2666166722006839?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2666166722006839?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,10,2]],"date-time":"2026-10-02T07:49:51Z","timestamp":1790927391000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2666166722006839"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,12]]},"references-count":5,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2022,12]]}},"alternative-id":["S2666166722006839"],"URL":"https:\/\/doi.org\/10.1016\/j.xpro.2022.101803","relation":{},"ISSN":["2666-1667"],"issn-type":[{"value":"2666-1667","type":"print"}],"subject":[],"published":{"date-parts":[[2022,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"An improved protocol for generation and characterization of human-induced pluripotent stem cell-derived retinal pigment epithelium cells","name":"articletitle","label":"Article Title"},{"value":"STAR Protocols","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.xpro.2022.101803","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"https:\/\/doi.org\/10.1016\/j.scr.2020.101757","name":"associatedlink","label":"CrossRef DOI link to the associated document"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2022 The Author(s).","name":"copyright","label":"Copyright"}],"article-number":"101803"}}