{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,10]],"date-time":"2026-04-10T08:30:41Z","timestamp":1775809841299,"version":"3.50.1"},"reference-count":4,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2023,3,1]],"date-time":"2023-03-01T00:00:00Z","timestamp":1677628800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,3,1]],"date-time":"2023-03-01T00:00:00Z","timestamp":1677628800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2023,1,20]],"date-time":"2023-01-20T00:00:00Z","timestamp":1674172800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/100006058","name":"St. Baldrick's Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100006058","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100010582","name":"NCI","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100010582","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["K08CA2560450"],"award-info":[{"award-number":["K08CA2560450"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000054","name":"National Cancer Institute","doi-asserted-by":"publisher","award":["P30CA014236"],"award-info":[{"award-number":["P30CA014236"]}],"id":[{"id":"10.13039\/100000054","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000054","name":"National Cancer Institute","doi-asserted-by":"publisher","award":["P50CA190991"],"award-info":[{"award-number":["P50CA190991"]}],"id":[{"id":"10.13039\/100000054","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000054","name":"National Cancer Institute","doi-asserted-by":"publisher","award":["R35CA197616"],"award-info":[{"award-number":["R35CA197616"]}],"id":[{"id":"10.13039\/100000054","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000054","name":"National Cancer Institute","doi-asserted-by":"publisher","award":["U19CA264385"],"award-info":[{"award-number":["U19CA264385"]}],"id":[{"id":"10.13039\/100000054","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100001794","name":"Pediatric Brain Tumor Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100001794","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["STAR Protocols"],"published-print":{"date-parts":[[2023,3]]},"DOI":"10.1016\/j.xpro.2023.102094","type":"journal-article","created":{"date-parts":[[2023,2,13]],"date-time":"2023-02-13T17:37:47Z","timestamp":1676309867000},"page":"102094","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":11,"title":["Inducing primary brainstem gliomas in genetically engineered mice using RCAS\/TVA retroviruses and Cre\/loxP recombination"],"prefix":"10.1016","volume":"4","author":[{"given":"Loren B.","family":"Weidenhammer","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Harrison Q.","family":"Liu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lixia","family":"Luo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nerissa T.","family":"Williams","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Katherine","family":"Deland","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David G.","family":"Kirsch","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zachary J.","family":"Reitman","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.xpro.2023.102094_bib1","doi-asserted-by":"crossref","first-page":"e142158","DOI":"10.1172\/JCI142158","article-title":"Tumor genotype dictates radiosensitization after Atm deletion in primary brainstem glioma models","volume":"131","author":"Deland","year":"2021","journal-title":"J.\u00a0Clin. Invest."},{"key":"10.1016\/j.xpro.2023.102094_bib2","doi-asserted-by":"crossref","first-page":"771","DOI":"10.1016\/j.ijrobp.2021.09.047","article-title":"Radiosensitizing the vasculature of primary brainstem gliomas fails to improve tumor response to radiation therapy","volume":"112","author":"Deland","year":"2022","journal-title":"Int. J. Radiat. Oncol. Biol. Phys."},{"key":"10.1016\/j.xpro.2023.102094_bib3","doi-asserted-by":"crossref","first-page":"4506","DOI":"10.3390\/cancers14184506","article-title":"The effect of Atm loss on radiosensitivity of a primary mouse model of Pten-deleted brainstem glioma","volume":"14","author":"Stewart","year":"2022","journal-title":"Cancers"},{"key":"10.1016\/j.xpro.2023.102094_bib4","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1593\/tlo.09100","article-title":"Modeling adult gliomas using RCAS\/t-va technology","volume":"2","author":"Hambardzumyan","year":"2009","journal-title":"Transl. Oncol."}],"container-title":["STAR Protocols"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2666166723000527?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2666166723000527?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,12]],"date-time":"2025-11-12T19:52:35Z","timestamp":1762977155000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2666166723000527"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,3]]},"references-count":4,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2023,3]]}},"alternative-id":["S2666166723000527"],"URL":"https:\/\/doi.org\/10.1016\/j.xpro.2023.102094","relation":{},"ISSN":["2666-1667"],"issn-type":[{"value":"2666-1667","type":"print"}],"subject":[],"published":{"date-parts":[[2023,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Inducing primary brainstem gliomas in genetically engineered mice using RCAS\/TVA retroviruses and Cre\/loxP recombination","name":"articletitle","label":"Article Title"},{"value":"STAR Protocols","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.xpro.2023.102094","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2023 The Authors.","name":"copyright","label":"Copyright"}],"article-number":"102094"}}