{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T03:56:57Z","timestamp":1790308617645,"version":"4.1.0"},"reference-count":11,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2023,6,1]],"date-time":"2023-06-01T00:00:00Z","timestamp":1685577600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,6,1]],"date-time":"2023-06-01T00:00:00Z","timestamp":1685577600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2023,4,24]],"date-time":"2023-04-24T00:00:00Z","timestamp":1682294400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100002426","name":"Fondazione Telethon","doi-asserted-by":"publisher","award":["GGP19146"],"award-info":[{"award-number":["GGP19146"]}],"id":[{"id":"10.13039\/501100002426","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002803","name":"Fondazione Cariplo","doi-asserted-by":"publisher","award":["2015-0552"],"award-info":[{"award-number":["2015-0552"]}],"id":[{"id":"10.13039\/501100002803","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002803","name":"Fondazione Cariplo","doi-asserted-by":"publisher","award":["2018-0511"],"award-info":[{"award-number":["2018-0511"]}],"id":[{"id":"10.13039\/501100002803","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002803","name":"Fondazione Cariplo","doi-asserted-by":"publisher","award":["2019-1560"],"award-info":[{"award-number":["2019-1560"]}],"id":[{"id":"10.13039\/501100002803","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003196","name":"Ministero della Salute","doi-asserted-by":"publisher","award":["RF-2019-12370896"],"award-info":[{"award-number":["RF-2019-12370896"]}],"id":[{"id":"10.13039\/501100003196","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100012352","name":"University of Milan","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100012352","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["STAR Protocols"],"published-print":{"date-parts":[[2023,6]]},"DOI":"10.1016\/j.xpro.2023.102301","type":"journal-article","created":{"date-parts":[[2023,5,19]],"date-time":"2023-05-19T16:55:46Z","timestamp":1684515346000},"page":"102301","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":1,"title":["Protocol to evaluate the impact of murine MCT1-deficient CD8+ T\u00a0cells on adipogenesis"],"prefix":"10.1016","volume":"4","author":[{"given":"Chiara","family":"Macchi","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Annalisa","family":"Moregola","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giuseppe Danilo","family":"Norata","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Massimiliano","family":"Ruscica","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.xpro.2023.102301_bib1","doi-asserted-by":"crossref","first-page":"104435","DOI":"10.1016\/j.isci.2022.104435","article-title":"Monocarboxylate transporter 1 deficiency impacts CD8(+) T lymphocytes proliferation and recruitment to adipose tissue during obesity","volume":"25","author":"Macchi","year":"2022","journal-title":"iScience"},{"key":"10.1016\/j.xpro.2023.102301_bib2","doi-asserted-by":"crossref","first-page":"6908","DOI":"10.1074\/jbc.M113.506394","article-title":"LT175 is a novel PPARalpha\/gamma ligand with potent insulin-sensitizing effects and reduced adipogenic properties","volume":"289","author":"Gilardi","year":"2014","journal-title":"J.\u00a0Biol. Chem."},{"key":"10.1016\/j.xpro.2023.102301_bib3","doi-asserted-by":"crossref","first-page":"e202202011","DOI":"10.1083\/jcb.202202011","article-title":"The low-density lipoprotein receptor-mTORC1 axis coordinates CD8+ T\u00a0cell activation","volume":"221","author":"Bonacina","year":"2022","journal-title":"J.\u00a0Cell Biol."},{"key":"10.1016\/j.xpro.2023.102301_bib4","doi-asserted-by":"crossref","first-page":"300","DOI":"10.1016\/j.cmet.2020.12.016","article-title":"Caloric restriction promotes immunometabolic reprogramming leading to protection from tuberculosis","volume":"33","author":"Palma","year":"2021","journal-title":"Cell Metab."},{"key":"10.1016\/j.xpro.2023.102301_bib5","doi-asserted-by":"crossref","first-page":"2226","DOI":"10.1016\/j.ajpath.2020.07.016","article-title":"Leptin, resistin, and proprotein convertase subtilisin\/Kexin type 9: the role of STAT3","volume":"190","author":"Macchi","year":"2020","journal-title":"Am. J. Pathol."},{"key":"10.1016\/j.xpro.2023.102301_bib6","doi-asserted-by":"crossref","first-page":"193","DOI":"10.3390\/nu14010193","article-title":"Impact of soy beta-conglycinin peptides on PCSK9 protein expression in HepG2 cells","volume":"14","author":"Macchi","year":"2021","journal-title":"Nutrients"},{"key":"10.1016\/j.xpro.2023.102301_bib7","doi-asserted-by":"crossref","first-page":"371","DOI":"10.1038\/nchembio744","article-title":"Monocarboxylate transporter MCT1 is a target for immunosuppression","volume":"1","author":"Murray","year":"2005","journal-title":"Nat. Chem. Biol."},{"key":"10.1016\/j.xpro.2023.102301_bib8","doi-asserted-by":"crossref","first-page":"2094","DOI":"10.1172\/JCI45887","article-title":"Adipose tissue remodeling and obesity","volume":"121","author":"Sun","year":"2011","journal-title":"J.\u00a0Clin. Invest."},{"key":"10.1016\/j.xpro.2023.102301_bib9","doi-asserted-by":"crossref","first-page":"914","DOI":"10.1038\/nm.1964","article-title":"CD8+ effector T\u00a0cells contribute to macrophage recruitment and adipose tissue inflammation in obesity","volume":"15","author":"Nishimura","year":"2009","journal-title":"Nat. Med."},{"key":"10.1016\/j.xpro.2023.102301_bib10","doi-asserted-by":"crossref","first-page":"172","DOI":"10.3389\/fimmu.2018.00172","article-title":"Establishment of the reference intervals of lymphocyte function in healthy adults based on IFN-gamma secretion assay upon phorbol-12-Myristate-13-acetate\/ionomycin stimulation","volume":"9","author":"Hou","year":"2018","journal-title":"Front. Immunol."},{"key":"10.1016\/j.xpro.2023.102301_bib11","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1007\/s00018-022-04169-6","article-title":"Regulatory mechanisms of the early phase of white adipocyte differentiation: an overview","volume":"79","author":"Audano","year":"2022","journal-title":"Cell. Mol. Life Sci."}],"container-title":["STAR Protocols"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S266616672300268X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S266616672300268X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,12]],"date-time":"2025-11-12T19:53:09Z","timestamp":1762977189000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S266616672300268X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,6]]},"references-count":11,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2023,6]]}},"alternative-id":["S266616672300268X"],"URL":"https:\/\/doi.org\/10.1016\/j.xpro.2023.102301","relation":{},"ISSN":["2666-1667"],"issn-type":[{"value":"2666-1667","type":"print"}],"subject":[],"published":{"date-parts":[[2023,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Protocol to evaluate the impact of murine MCT1-deficient CD8+ T\u00a0cells on adipogenesis","name":"articletitle","label":"Article Title"},{"value":"STAR Protocols","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.xpro.2023.102301","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"https:\/\/doi.org\/10.1016\/j.isci.2022.104435","name":"associatedlink","label":"CrossRef DOI link to the associated document"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2023 The Author(s).","name":"copyright","label":"Copyright"}],"article-number":"102301"}}