{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,21]],"date-time":"2026-09-21T15:41:50Z","timestamp":1790005310221,"version":"4.0.1"},"reference-count":6,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2026,3,1]],"date-time":"2026-03-01T00:00:00Z","timestamp":1772323200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,3,1]],"date-time":"2026-03-01T00:00:00Z","timestamp":1772323200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,2,13]],"date-time":"2026-02-13T00:00:00Z","timestamp":1770940800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100002347","name":"Federal Ministry of Education and Research Bonn Office","doi-asserted-by":"publisher","award":["03Z22DN11"],"award-info":[{"award-number":["03Z22DN11"]}],"id":[{"id":"10.13039\/501100002347","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002347","name":"Federal Ministry of Education and Research Bonn Office","doi-asserted-by":"publisher","award":["03Z22Di1"],"award-info":[{"award-number":["03Z22Di1"]}],"id":[{"id":"10.13039\/501100002347","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["cell.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["STAR Protocols"],"published-print":{"date-parts":[[2026,3]]},"DOI":"10.1016\/j.xpro.2026.104416","type":"journal-article","created":{"date-parts":[[2026,3,5]],"date-time":"2026-03-05T10:42:55Z","timestamp":1772707375000},"page":"104416","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":1,"title":["Protocol for generating a 3D hydrogel-based tumor resection model in vitro using pancreatic cancer cells"],"prefix":"10.1016","volume":"7","author":[{"given":"Lea","family":"Miebach","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marten","family":"Hagge","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Linus","family":"H\u00fcbner","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8773-8862","authenticated-orcid":false,"given":"Sander","family":"Bekeschus","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.xpro.2026.104416_bib1","doi-asserted-by":"crossref","first-page":"2818","DOI":"10.1016\/j.tibtech.2025.07.004","article-title":"Gas plasma technology mediates deep tissue and anticancer events independently of hydrogen peroxide","volume":"43","author":"Miebach","year":"2025","journal-title":"Trends Biotechnol."},{"key":"10.1016\/j.xpro.2026.104416_bib2","doi-asserted-by":"crossref","first-page":"1055","DOI":"10.1002\/bjs.11115","article-title":"Impact of resection margin status on recurrence and survival in pancreatic cancer surgery","volume":"106","author":"Tummers","year":"2019","journal-title":"Br. J. Surg."},{"key":"10.1016\/j.xpro.2026.104416_bib3","first-page":"29","article-title":"The effect of the surgical margins on the outcome of patients with head and neck squamous cell carcinoma: single institution experience","volume":"9","author":"Eldeeb","year":"2012","journal-title":"Cancer Biol. Med."},{"key":"10.1016\/j.xpro.2026.104416_bib4","doi-asserted-by":"crossref","first-page":"6591","DOI":"10.2147\/CMAR.S181843","article-title":"Classification of positive surgical margins and tumor recurrence after nephron-sparing surgery for small renal masses","volume":"10","author":"Li","year":"2018","journal-title":"Cancer Manag. Res."},{"key":"10.1016\/j.xpro.2026.104416_bib5","first-page":"910","article-title":"2D and 3D cell cultures\u2013a comparison of different types of cancer cell cultures","volume":"14","author":"Kapa\u0142czy\u0144ska","year":"2018","journal-title":"Arch. Med. Sci."},{"key":"10.1016\/j.xpro.2026.104416_bib6","doi-asserted-by":"crossref","DOI":"10.3390\/cancers17071161","article-title":"Mimicking the Complexity of Solid Tumors: How Spheroids Could Advance Cancer Preclinical Transformative Approaches","volume":"17","author":"Mangani","year":"2025","journal-title":"Cancers (Basel)"}],"container-title":["STAR Protocols"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2666166726000699?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2666166726000699?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,7,2]],"date-time":"2026-07-02T20:58:10Z","timestamp":1783025890000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2666166726000699"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,3]]},"references-count":6,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2026,3]]}},"alternative-id":["S2666166726000699"],"URL":"https:\/\/doi.org\/10.1016\/j.xpro.2026.104416","relation":{},"ISSN":["2666-1667"],"issn-type":[{"value":"2666-1667","type":"print"}],"subject":[],"published":{"date-parts":[[2026,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Protocol for generating a 3D hydrogel-based tumor resection model in vitro using pancreatic cancer cells","name":"articletitle","label":"Article Title"},{"value":"STAR Protocols","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.xpro.2026.104416","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 The Author(s). Published by Elsevier Inc.","name":"copyright","label":"Copyright"}],"article-number":"104416"}}