{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,24]],"date-time":"2025-09-24T20:40:01Z","timestamp":1758746401331,"version":"3.44.0"},"reference-count":110,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2007,1,1]],"date-time":"2007-01-01T00:00:00Z","timestamp":1167609600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2007,1,1]],"date-time":"2007-01-01T00:00:00Z","timestamp":1167609600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["advancesinpediatrics.com","clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Advances in Pediatrics"],"published-print":{"date-parts":[[2007]]},"DOI":"10.1016\/j.yapd.2007.03.004","type":"journal-article","created":{"date-parts":[[2007,8,18]],"date-time":"2007-08-18T07:16:34Z","timestamp":1187421394000},"page":"29-53","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"title":["Advances in Pediatric Pharmacology, Therapeutics, and Toxicology"],"prefix":"10.1016","volume":"54","author":[{"given":"Ian M.","family":"Paul","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.yapd.2007.03.004_bib1","unstructured":"American Academy of Pediatrics. Available at: http:\/\/www.aap.org\/advocacy\/releases\/feb0575.htm. Accessed December 4, 2006."},{"issue":"231","key":"10.1016\/j.yapd.2007.03.004_bib2","first-page":"66631","article-title":"Regulations requiring manufacturers to assess the safety and effectiveness of new drugs and biological products in pediatric patients\u2014FDA. Final rule","volume":"63","year":"1998","journal-title":"Fed Regist"},{"issue":"25","key":"10.1016\/j.yapd.2007.03.004_bib3","doi-asserted-by":"crossref","first-page":"2653","DOI":"10.1056\/NEJM200506233522522","article-title":"Boxed warning added to promethazine labeling for pediatric use","volume":"352","author":"Starke","year":"2005","journal-title":"N Engl J Med"},{"issue":"3 Pt 2","key":"10.1016\/j.yapd.2007.03.004_bib4","doi-asserted-by":"crossref","first-page":"585","DOI":"10.1542\/peds.104.S3.585","article-title":"An update on the therapeutic orphan","volume":"104","author":"Wilson","year":"1999","journal-title":"Pediatrics"},{"key":"10.1016\/j.yapd.2007.03.004_bib5","unstructured":"US Food and Drug Administration. Approved active moieties to which FDA has granted pediatric exclusivity for pediatric studies under Section 505A of the Federal Food, Drug,\u00a0and Cosmetic Act. Available at: http:\/\/www.fda.gov\/cder\/pediatric\/exgrant.htm. Accessed December 4, 2006."},{"issue":"11","key":"10.1016\/j.yapd.2007.03.004_bib6","doi-asserted-by":"crossref","first-page":"1363","DOI":"10.1001\/jama.292.11.1363","article-title":"Clinical trial registration: a statement from the International Committee of Medical Journal Editors","volume":"292","author":"DeAngelis","year":"2004","journal-title":"JAMA"},{"issue":"3","key":"10.1016\/j.yapd.2007.03.004_bib7","doi-asserted-by":"crossref","first-page":"e378","DOI":"10.1542\/peds.2004-0759","article-title":"Social medication and the control of children: a qualitative study of over-the-counter medication among Australian children","volume":"114","author":"Allotey","year":"2004","journal-title":"Pediatrics"},{"issue":"2","key":"10.1016\/j.yapd.2007.03.004_bib8","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1001\/archpedi.160.2.197","article-title":"Antipyretic treatment in young children with fever: acetaminophen, ibuprofen, or both alternating in a randomized, double-blind study","volume":"160","author":"Sarrell","year":"2006","journal-title":"Arch Pediatr Adolesc Med"},{"issue":"5","key":"10.1016\/j.yapd.2007.03.004_bib9","doi-asserted-by":"crossref","first-page":"414","DOI":"10.1136\/adc.2005.087874","article-title":"Randomised controlled trial of combined paracetamol and ibuprofen for fever","volume":"91","author":"Erlewyn-Lajeunesse","year":"2006","journal-title":"Arch Dis Child"},{"issue":"4","key":"10.1016\/j.yapd.2007.03.004_bib10","doi-asserted-by":"crossref","first-page":"1020","DOI":"10.1542\/peds.108.4.1020","article-title":"Acetaminophen toxicity in children","volume":"108","year":"2001","journal-title":"Pediatrics"},{"issue":"5","key":"10.1016\/j.yapd.2007.03.004_bib11","doi-asserted-by":"crossref","first-page":"762","DOI":"10.1016\/j.clinthera.2006.05.005","article-title":"Antipyretic efficacy and tolerability of a single intravenous dose of the acetaminophen prodrug propacetamol in children: a randomized, double-blind, placebo-controlled trial","volume":"28","author":"Walson","year":"2006","journal-title":"Clin Ther"},{"issue":"6","key":"10.1016\/j.yapd.2007.03.004_bib12","doi-asserted-by":"crossref","first-page":"918","DOI":"10.1542\/peds.99.6.918","article-title":"Use of codeine- and dextromethorphan-containing cough remedies in children. American Academy of Pediatrics. Committee on Drugs","volume":"99","year":"1997","journal-title":"Pediatrics"},{"issue":"1","key":"10.1016\/j.yapd.2007.03.004_bib13","doi-asserted-by":"crossref","first-page":"e85","DOI":"10.1542\/peds.114.1.e85","article-title":"Effect of dextromethorphan, diphenhydramine, and placebo on nocturnal cough and sleep quality for coughing children and their parents","volume":"114","author":"Paul","year":"2004","journal-title":"Pediatrics"},{"issue":"1 Suppl","key":"10.1016\/j.yapd.2007.03.004_bib14","doi-asserted-by":"crossref","first-page":"260S","DOI":"10.1378\/chest.129.1_suppl.260S","article-title":"Guidelines for evaluating chronic cough in pediatrics: ACCP evidence-based clinical practice guidelines","volume":"129","author":"Chang","year":"2006","journal-title":"Chest"},{"key":"10.1016\/j.yapd.2007.03.004_bib15","unstructured":"US Food and Drug Administration. Available at: http:\/\/www.fda.gov\/ohrms\/dockets\/98fr\/E6\u20138982.pdf. Accessed December 5, 2006."},{"key":"10.1016\/j.yapd.2007.03.004_bib16","unstructured":"US Food and Drug Administration. Novartis Consumer Health conducts nationwide voluntary recall of Triaminic Vapor Patch product in U.S. Available at: http:\/\/www.fda.gov\/oc\/po\/firmrecalls\/Novartis6_06.html. Accessed December 5, 2006."},{"issue":"13","key":"10.1016\/j.yapd.2007.03.004_bib17","doi-asserted-by":"crossref","first-page":"1306","DOI":"10.1056\/NEJMoa033534","article-title":"A randomized trial of a single dose of oral dexamethasone for mild croup","volume":"351","author":"Bjornson","year":"2004","journal-title":"N Engl J Med"},{"issue":"11","key":"10.1016\/j.yapd.2007.03.004_bib18","doi-asserted-by":"crossref","first-page":"1274","DOI":"10.1001\/jama.295.11.1274","article-title":"Controlled delivery of high vs low humidity vs mist therapy for croup in emergency departments: a randomized controlled trial","volume":"295","author":"Scolnik","year":"2006","journal-title":"JAMA"},{"issue":"3","key":"10.1016\/j.yapd.2007.03.004_bib19","doi-asserted-by":"crossref","first-page":"278","DOI":"10.1001\/archpedi.159.3.278","article-title":"Effectiveness of oral dexamethasone in the treatment of moderate- to-severe pharyngitis in children","volume":"159","author":"Olympia","year":"2005","journal-title":"Arch Pediatr Adolesc Med"},{"issue":"18","key":"10.1016\/j.yapd.2007.03.004_bib20","doi-asserted-by":"crossref","first-page":"2315","DOI":"10.1001\/jama.294.18.2315","article-title":"Antibiotic treatment of children with sore throat","volume":"294","author":"Linder","year":"2005","journal-title":"JAMA"},{"key":"10.1016\/j.yapd.2007.03.004_bib21","unstructured":"US Food and Drug Administration. Promethazine Hydrochloride. Available at: http:\/\/www.fda.gov\/cder\/drug\/InfoSheets\/HCP\/promethazineHCP.pdf. Accessed December 5, 2006."},{"issue":"16","key":"10.1016\/j.yapd.2007.03.004_bib22","doi-asserted-by":"crossref","first-page":"1698","DOI":"10.1056\/NEJMoa055119","article-title":"Oral ondansetron for gastroenteritis in a pediatric emergency department","volume":"354","author":"Freedman","year":"2006","journal-title":"N Engl J Med"},{"issue":"10","key":"10.1016\/j.yapd.2007.03.004_bib23","doi-asserted-by":"crossref","first-page":"909","DOI":"10.1097\/01.inf.0000180573.21718.36","article-title":"Meta-analysis of short course antibiotic treatment for group a streptococcal tonsillopharyngitis","volume":"24","author":"Casey","year":"2005","journal-title":"Pediatr Infect Dis J"},{"issue":"4","key":"10.1016\/j.yapd.2007.03.004_bib24","doi-asserted-by":"crossref","first-page":"927","DOI":"10.1542\/peds.2004-2294","article-title":"Explaining the poor bacteriologic eradication rate of single-dose ceftriaxone in group a streptococcal tonsillopharyngitis: a reverse engineering solution using pharmacodynamic modeling","volume":"116","author":"Blumer","year":"2005","journal-title":"Pediatrics"},{"issue":"2","key":"10.1016\/j.yapd.2007.03.004_bib25","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1097\/01.inf.0000151024.11703.4a","article-title":"A randomized, multicenter, double-blind, double dummy trial of single dose azithromycin versus high-dose amoxicillin for treatment of uncomplicated acute otitis media","volume":"24","author":"Arguedas","year":"2005","journal-title":"Pediatr Infect Dis J"},{"issue":"6","key":"10.1016\/j.yapd.2007.03.004_bib26","doi-asserted-by":"crossref","first-page":"525","DOI":"10.1097\/01.inf.0000164794.50281.1a","article-title":"Large dosage amoxicillin\/clavulanate compared with azithromycin for the treatment of bacterial acute otitis media in children","volume":"24","author":"Hoberman","year":"2005","journal-title":"Pediatr Infect Dis J"},{"issue":"4 Suppl","key":"10.1016\/j.yapd.2007.03.004_bib27","first-page":"S24","article-title":"Systematic review of topical antimicrobial therapy for acute otitis externa","volume":"134","author":"Rosenfeld","year":"2006","journal-title":"Otolaryngol Head Neck Surg"},{"issue":"4 Suppl","key":"10.1016\/j.yapd.2007.03.004_bib28","first-page":"S4","article-title":"Clinical practice guideline: acute otitis externa","volume":"134","author":"Rosenfeld","year":"2006","journal-title":"Otolaryngol Head Neck Surg"},{"issue":"9440","key":"10.1016\/j.yapd.2007.03.004_bib29","doi-asserted-by":"crossref","first-page":"1141","DOI":"10.1016\/S0140-6736(04)17100-6","article-title":"Oral amoxicillin versus injectable penicillin for severe pneumonia in children aged 3 to 59 months: a randomised multicentre equivalency study","volume":"364","author":"Addo-Yobo","year":"2004","journal-title":"Lancet"},{"issue":"3","key":"10.1016\/j.yapd.2007.03.004_bib30","doi-asserted-by":"crossref","first-page":"626","DOI":"10.1542\/peds.2005-1362","article-title":"Clinical significance of primary vesicoureteral reflux and urinary antibiotic prophylaxis after acute pyelonephritis: a multicenter, randomized, controlled study","volume":"117","author":"Garin","year":"2006","journal-title":"Pediatrics"},{"issue":"9491","key":"10.1016\/j.yapd.2007.03.004_bib31","doi-asserted-by":"crossref","first-page":"1085","DOI":"10.1016\/S0140-6736(05)67290-X","article-title":"Single-dose ciprofloxacin versus 12-dose erythromycin for childhood cholera: a randomised controlled trial","volume":"366","author":"Saha","year":"2005","journal-title":"Lancet"},{"issue":"5","key":"10.1016\/j.yapd.2007.03.004_bib32","doi-asserted-by":"crossref","first-page":"1312","DOI":"10.1542\/peds.2004-0428","article-title":"Griseofulvin versus terbinafine in the treatment of tinea capitis: a meta-analysis of randomized, clinical trials","volume":"114","author":"Fleece","year":"2004","journal-title":"Pediatrics"},{"issue":"10","key":"10.1016\/j.yapd.2007.03.004_bib33","doi-asserted-by":"crossref","first-page":"886","DOI":"10.1097\/01.inf.0000180577.29853.a0","article-title":"Pharmacokinetics of terbinafine in young children treated for tinea capitis","volume":"24","author":"Abdel-Rahman","year":"2005","journal-title":"Pediatr Infect Dis J"},{"issue":"5","key":"10.1016\/j.yapd.2007.03.004_bib34","doi-asserted-by":"crossref","first-page":"1010","DOI":"10.1002\/hep.20884","article-title":"Interferon alfa-2b in combination with ribavirin for the treatment of chronic hepatitis C in children: efficacy, safety, and pharmacokinetics","volume":"42","author":"Gonzalez-Peralta","year":"2005","journal-title":"Hepatology"},{"issue":"19","key":"10.1016\/j.yapd.2007.03.004_bib35","doi-asserted-by":"crossref","first-page":"1985","DOI":"10.1056\/NEJMoa051378","article-title":"Long-term inhaled corticosteroids in preschool children at high risk for asthma","volume":"354","author":"Guilbert","year":"2006","journal-title":"N Engl J Med"},{"issue":"19","key":"10.1016\/j.yapd.2007.03.004_bib36","doi-asserted-by":"crossref","first-page":"1998","DOI":"10.1056\/NEJMoa054692","article-title":"Intermittent inhaled corticosteroids in infants with episodic wheezing","volume":"354","author":"Bisgaard","year":"2006","journal-title":"N Engl J Med"},{"issue":"2","key":"10.1016\/j.yapd.2007.03.004_bib37","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1016\/j.jaci.2004.11.014","article-title":"Characterization of within-subject responses to fluticasone and montelukast in childhood asthma","volume":"115","author":"Szefler","year":"2005","journal-title":"J Allergy Clin Immunol"},{"issue":"1","key":"10.1016\/j.yapd.2007.03.004_bib38","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1016\/j.jaci.2005.10.012","article-title":"Response profiles to fluticasone and montelukast in mild-to-moderate persistent childhood asthma","volume":"117","author":"Zeiger","year":"2006","journal-title":"J Allergy Clin Immunol"},{"issue":"2","key":"10.1016\/j.yapd.2007.03.004_bib39","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1016\/j.jpeds.2005.03.052","article-title":"Comparative efficacy and safety of low-dose fluticasone propionate and montelukast in children with persistent asthma","volume":"147","author":"Ostrom","year":"2005","journal-title":"J Pediatr"},{"issue":"2","key":"10.1016\/j.yapd.2007.03.004_bib40","doi-asserted-by":"crossref","first-page":"360","DOI":"10.1542\/peds.2004-1172","article-title":"Montelukast, compared with fluticasone, for control of asthma among 6- to 14-year-old patients with mild asthma: the MOSAIC study","volume":"116","author":"Garcia Garcia","year":"2005","journal-title":"Pediatrics"},{"key":"10.1016\/j.yapd.2007.03.004_bib41","unstructured":"US Food and Drug Administration. FDA public health advisory. Available at: http:\/\/www.fda.gov\/cder\/drug\/advisory\/LABA.htm. Accessed December 11, 2006."},{"issue":"9481","key":"10.1016\/j.yapd.2007.03.004_bib42","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1016\/S0140-6736(05)66909-7","article-title":"Safety and efficacy of buccal midazolam versus rectal diazepam for emergency treatment of seizures in children: a randomised controlled trial","volume":"366","author":"McIntyre","year":"2005","journal-title":"Lancet"},{"issue":"9522","key":"10.1016\/j.yapd.2007.03.004_bib43","doi-asserted-by":"crossref","first-page":"1591","DOI":"10.1016\/S0140-6736(06)68696-0","article-title":"Efficacy and safety of intranasal lorazepam versus intramuscular paraldehyde for protracted convulsions in children: an open randomised trial","volume":"367","author":"Ahmad","year":"2006","journal-title":"Lancet"},{"issue":"12","key":"10.1016\/j.yapd.2007.03.004_bib44","doi-asserted-by":"crossref","first-page":"2215","DOI":"10.1212\/01.WNL.0000147332.41993.90","article-title":"Practice parameter: pharmacological treatment of migraine headache in children and adolescents: report of the American Academy of Neurology Quality Standards Subcommittee and the Practice Committee of the Child Neurology Society","volume":"63","author":"Lewis","year":"2004","journal-title":"Neurology"},{"key":"10.1016\/j.yapd.2007.03.004_bib45","unstructured":"US Food and Drug Administration. FDA takes action on Plan B statement. Available at: http:\/\/www.fda.gov\/bbs\/topics\/NEWS\/2005\/NEW01251.html. Accessed December 14, 2006."},{"issue":"15","key":"10.1016\/j.yapd.2007.03.004_bib46","doi-asserted-by":"crossref","first-page":"3396","DOI":"10.1200\/JCO.2005.03.199","article-title":"Phase I study of 506U78 administered on a consecutive 5-day schedule in children and adults with refractory hematologic malignancies","volume":"23","author":"Kurtzberg","year":"2005","journal-title":"J\u00a0Clin Oncol"},{"issue":"2","key":"10.1016\/j.yapd.2007.03.004_bib47","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1056\/NEJMoa035153","article-title":"The effect of dexrazoxane on myocardial injury in doxorubicin-treated children with acute lymphoblastic leukemia","volume":"351","author":"Lipshultz","year":"2004","journal-title":"N Engl J Med"},{"issue":"3","key":"10.1016\/j.yapd.2007.03.004_bib48","doi-asserted-by":"crossref","first-page":"353","DOI":"10.1016\/j.jpeds.2004.04.009","article-title":"A randomized, placebo-controlled trial of amlodipine in children with hypertension","volume":"145","author":"Flynn","year":"2004","journal-title":"J Pediatr"},{"issue":"2","key":"10.1016\/j.yapd.2007.03.004_bib49","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1016\/j.jpeds.2006.03.050","article-title":"Prediction of resistance to intravenous immunoglobulin treatment in patients with Kawasaki disease","volume":"149","author":"Egami","year":"2006","journal-title":"J Pediatr"},{"issue":"1","key":"10.1016\/j.yapd.2007.03.004_bib50","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1016\/j.jpeds.2005.08.024","article-title":"Clinical responses of patients with Kawasaki disease to different brands of intravenous immunoglobulin","volume":"148","author":"Tsai","year":"2006","journal-title":"J Pediatr"},{"issue":"5","key":"10.1016\/j.yapd.2007.03.004_bib51","doi-asserted-by":"crossref","first-page":"662","DOI":"10.1016\/j.jpeds.2004.12.022","article-title":"Infliximab treatment for refractory Kawasaki syndrome","volume":"146","author":"Burns","year":"2005","journal-title":"J Pediatr"},{"issue":"4","key":"10.1016\/j.yapd.2007.03.004_bib52","doi-asserted-by":"crossref","first-page":"989","DOI":"10.1542\/peds.2005-0504","article-title":"Effect of initial corticosteroid therapy on coronary artery aneurysm formation in Kawasaki disease: a meta-analysis of 862 children","volume":"116","author":"Wooditch","year":"2005","journal-title":"Pediatrics"},{"key":"10.1016\/j.yapd.2007.03.004_bib53","unstructured":"US Food and Drug Administration. FDA public health advisory. Available at: http:\/\/www.fda.gov\/cder\/drug\/advisory\/elidel_protopic.htm. Accessed December 14, 2006."},{"key":"10.1016\/j.yapd.2007.03.004_bib54","unstructured":"US Food and Drug Administration. Isotretinoin (marketed as Accutane) capsule information. Available at: http:\/\/www.fda.gov\/cder\/drug\/infopage\/accutane\/default.htm. Accessed December 15, 2006."},{"issue":"3","key":"10.1016\/j.yapd.2007.03.004_bib55","doi-asserted-by":"crossref","first-page":"1871","DOI":"10.1210\/jc.2004-1389","article-title":"Childhood obesity","volume":"90","author":"Speiser","year":"2005","journal-title":"J Clin Endocrinol Metab"},{"issue":"3","key":"10.1016\/j.yapd.2007.03.004_bib56","doi-asserted-by":"crossref","first-page":"1460","DOI":"10.1210\/jc.2004-0263","article-title":"Treatment of obese adolescents with sibutramine: a randomized, double-blind, controlled study","volume":"90","author":"Godoy-Matos","year":"2005","journal-title":"J Clin Endocrinol Metab"},{"issue":"5","key":"10.1016\/j.yapd.2007.03.004_bib57","doi-asserted-by":"crossref","first-page":"770","DOI":"10.1016\/j.clinthera.2006.05.008","article-title":"Use of sibutramine in obese Mexican adolescents: a 6-month, randomized, double-blind, placebo-controlled, parallel-group trial","volume":"28","author":"Garcia-Morales","year":"2006","journal-title":"Clin Ther"},{"issue":"23","key":"10.1016\/j.yapd.2007.03.004_bib58","doi-asserted-by":"crossref","first-page":"2873","DOI":"10.1001\/jama.293.23.2873","article-title":"Effect of orlistat on weight and body composition in obese adolescents: a randomized controlled trial","volume":"293","author":"Chanoine","year":"2005","journal-title":"JAMA"},{"issue":"1","key":"10.1016\/j.yapd.2007.03.004_bib59","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1093\/humrep\/deg056","article-title":"Low-dose combination of flutamide, metformin, and an oral contraceptive for nonobese, young women with polycystic ovary syndrome","volume":"18","author":"Ibanez","year":"2003","journal-title":"Hum Reprod"},{"key":"10.1016\/j.yapd.2007.03.004_bib60","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1016\/S0031-398X(06)71244-9","article-title":"FDA OKs single-rod implantable contraceptive","volume":"8","author":"Mechcatie","year":"2006","journal-title":"Pediatr News"},{"key":"10.1016\/j.yapd.2007.03.004_bib61","unstructured":"US Food and Drug Administration. Statement on Adderall. Available at: http:\/\/www.fda.gov\/bbs\/topics\/news\/2005\/NEW01262.html. Accessed December 15, 2006."},{"issue":"1","key":"10.1016\/j.yapd.2007.03.004_bib62","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1001\/archpedi.160.1.40","article-title":"Weight gain in obese and nonobese adolescent girls initiating depot medroxyprogesterone, oral contraceptive pills, or no hormonal contraceptive method","volume":"160","author":"Bonny","year":"2006","journal-title":"Arch Pediatr Adolesc Med"},{"issue":"2","key":"10.1016\/j.yapd.2007.03.004_bib63","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1001\/archpedi.159.2.139","article-title":"Change in bone mineral density among adolescent women using and discontinuing depot medroxyprogesterone acetate contraception","volume":"159","author":"Scholes","year":"2005","journal-title":"Arch Pediatr Adolesc Med"},{"issue":"4","key":"10.1016\/j.yapd.2007.03.004_bib64","doi-asserted-by":"crossref","first-page":"1158","DOI":"10.1016\/j.ajog.2004.05.011","article-title":"Tolerability of levonorgestrel emergency contraception in adolescents","volume":"191","author":"Harper","year":"2004","journal-title":"Am J Obstet Gynecol"},{"issue":"4","key":"10.1016\/j.yapd.2007.03.004_bib65","doi-asserted-by":"crossref","first-page":"1026","DOI":"10.1542\/peds.2005-1877","article-title":"Emergency contraception","volume":"116","year":"2005","journal-title":"Pediatrics"},{"issue":"1","key":"10.1016\/j.yapd.2007.03.004_bib66","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1001\/jama.293.1.54","article-title":"Direct access to emergency contraception through pharmacies and effect on unintended pregnancy and STIs: a randomized controlled trial","volume":"293","author":"Raine","year":"2005","journal-title":"JAMA"},{"issue":"3","key":"10.1016\/j.yapd.2007.03.004_bib67","doi-asserted-by":"crossref","first-page":"483","DOI":"10.1097\/01.AOG.0000174000.37962.a1","article-title":"The effect of increased access to emergency contraception among young adolescents","volume":"106","author":"Harper","year":"2005","journal-title":"Obstet Gynecol"},{"issue":"6","key":"10.1016\/j.yapd.2007.03.004_bib68","doi-asserted-by":"crossref","first-page":"e749","DOI":"10.1542\/peds.2004-2560","article-title":"Treatment of attention-deficit\/hyperactivity disorder: overview of the evidence","volume":"115","author":"Brown","year":"2005","journal-title":"Pediatrics"},{"issue":"6","key":"10.1016\/j.yapd.2007.03.004_bib69","doi-asserted-by":"crossref","first-page":"1734","DOI":"10.1542\/peds.2004-1959","article-title":"Attention-deficit\/hyperactivity disorder among adolescents: a review of the diagnosis, treatment, and clinical implications","volume":"115","author":"Wolraich","year":"2005","journal-title":"Pediatrics"},{"key":"10.1016\/j.yapd.2007.03.004_bib70","unstructured":"Health Canada. Health Canada suspends the market authorization of ADDERALL XR, a drug prescribed for attention deficit hyperactivity disorder (ADHD) in children. Available at: http:\/\/www.hc-sc.gc.ca\/ahc-asc\/media\/advisories-avis\/2005\/2005_01_e.html. Accessed December 19, 2006."},{"key":"10.1016\/j.yapd.2007.03.004_bib71","unstructured":"US Food and Drug Administration. Public health advisory for Adderall and Adderall XR. Available at: http:\/\/www.fda.gov\/cder\/drug\/advisory\/adderall.htm. Accessed December 19, 2006."},{"issue":"3","key":"10.1016\/j.yapd.2007.03.004_bib72","doi-asserted-by":"crossref","first-page":"348","DOI":"10.1016\/j.jpeds.2005.03.014","article-title":"Short- and long-term cardiovascular effects of mixed amphetamine salts extended release in children","volume":"147","author":"Findling","year":"2005","journal-title":"J Pediatr"},{"key":"10.1016\/j.yapd.2007.03.004_bib73","unstructured":"US Food and Drug Administration. FDA issues public health advisory on Strattera (Atomoxetine) for attention deficit disorder. Available at: http:\/\/www.fda.gov\/bbs\/topics\/news\/2005\/new01237.html. Accessed December 19, 2006."},{"issue":"7","key":"10.1016\/j.yapd.2007.03.004_bib74","doi-asserted-by":"crossref","first-page":"807","DOI":"10.1001\/jama.292.7.807","article-title":"Fluoxetine, cognitive\u2013behavioral therapy, and their combination for adolescents with depression: Treatment for Adolescents With Depression Study (TADS) randomized controlled trial","volume":"292","author":"March","year":"2004","journal-title":"JAMA"},{"key":"10.1016\/j.yapd.2007.03.004_bib75","unstructured":"US Food and Drug Administration. Labeling change request letter for antidepressant medications. Available at: http:\/\/www.fda.gov\/cder\/drug\/antidepressants\/SSRIlabelChange.htm. Accessed December 21, 2006."},{"issue":"1","key":"10.1016\/j.yapd.2007.03.004_bib76","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1542\/peds.2005-0074","article-title":"The Food and Drug Administration's deliberations on antidepressant use in pediatric patients","volume":"116","author":"Leslie","year":"2005","journal-title":"Pediatrics"},{"issue":"1","key":"10.1016\/j.yapd.2007.03.004_bib77","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1176\/appi.ajp.163.1.41","article-title":"Suicide risk during antidepressant treatment","volume":"163","author":"Simon","year":"2006","journal-title":"Am J Psychiatry"},{"issue":"3","key":"10.1016\/j.yapd.2007.03.004_bib78","doi-asserted-by":"crossref","first-page":"332","DOI":"10.1001\/archpsyc.63.3.332","article-title":"Suicidality in pediatric patients treated with antidepressant drugs","volume":"63","author":"Hammad","year":"2006","journal-title":"Arch Gen Psychiatry"},{"issue":"5","key":"10.1016\/j.yapd.2007.03.004_bib79","doi-asserted-by":"crossref","first-page":"567","DOI":"10.1016\/j.jpeds.2006.04.023","article-title":"Treating pediatric depression in primary care: coping with the patient's blue mood and the FDA's black box","volume":"148","author":"Rappaport","year":"2006","journal-title":"J Pediatr"},{"issue":"5","key":"10.1016\/j.yapd.2007.03.004_bib80","doi-asserted-by":"crossref","first-page":"e634","DOI":"10.1542\/peds.2003-0264-F","article-title":"Risperidone in the treatment of disruptive behavioral symptoms in children with autistic and other pervasive developmental disorders","volume":"114","author":"Shea","year":"2004","journal-title":"Pediatrics"},{"issue":"11","key":"10.1016\/j.yapd.2007.03.004_bib81","doi-asserted-by":"crossref","first-page":"1137","DOI":"10.1097\/01.chi.0000177055.11229.76","article-title":"Long-term effects of risperidone in children with autism spectrum disorders: a placebo discontinuation study","volume":"44","author":"Troost","year":"2005","journal-title":"J Am Acad Child Adolesc Psychiatry"},{"issue":"6","key":"10.1016\/j.yapd.2007.03.004_bib82","doi-asserted-by":"crossref","first-page":"796","DOI":"10.1016\/j.clinthera.2005.06.008","article-title":"Newborns and drug studies: the NICHD\/FDA newborn drug development initiative","volume":"27","author":"Giacoia","year":"2005","journal-title":"Clin Ther"},{"issue":"3 Pt 2","key":"10.1016\/j.yapd.2007.03.004_bib83","doi-asserted-by":"crossref","first-page":"S1","DOI":"10.1542\/peds.2005-0620B","article-title":"The newborn drug development initiative","volume":"117","author":"Giacoia","year":"2006","journal-title":"Pediatrics"},{"issue":"6","key":"10.1016\/j.yapd.2007.03.004_bib84","doi-asserted-by":"crossref","first-page":"1979","DOI":"10.1542\/peds.2005-1707","article-title":"Reported medication use in the neonatal intensive care unit: data from a large national data set","volume":"117","author":"Clark","year":"2006","journal-title":"Pediatrics"},{"issue":"20","key":"10.1016\/j.yapd.2007.03.004_bib85","doi-asserted-by":"crossref","first-page":"2112","DOI":"10.1056\/NEJMoa054065","article-title":"Caffeine therapy for apnea of prematurity","volume":"354","author":"Schmidt","year":"2006","journal-title":"N Engl J\u00a0Med"},{"issue":"6","key":"10.1016\/j.yapd.2007.03.004_bib86","doi-asserted-by":"crossref","first-page":"1649","DOI":"10.1542\/peds.2004-1159","article-title":"Prophylaxis of early adrenal insufficiency to prevent bronchopulmonary dysplasia: a multicenter trial","volume":"114","author":"Watterberg","year":"2004","journal-title":"Pediatrics"},{"issue":"2","key":"10.1016\/j.yapd.2007.03.004_bib87","doi-asserted-by":"crossref","first-page":"367","DOI":"10.1542\/peds.2005-0869","article-title":"A double-blind, randomized, controlled study of a stress dose of hydrocortisone for rescue treatment of refractory hypotension in preterm infants","volume":"117","author":"Ng","year":"2006","journal-title":"Pediatrics"},{"issue":"3","key":"10.1016\/j.yapd.2007.03.004_bib88","doi-asserted-by":"crossref","first-page":"704","DOI":"10.1542\/peds.2005-0796","article-title":"Prospective evaluation of postnatal steroid administration: a 1-year experience from the California Perinatal Quality Care Collaborative","volume":"117","author":"Finer","year":"2006","journal-title":"Pediatrics"},{"issue":"2","key":"10.1016\/j.yapd.2007.03.004_bib89","doi-asserted-by":"crossref","first-page":"466","DOI":"10.1016\/j.ajog.2005.07.098","article-title":"Optimal timing of ampicillin administration to pregnant women for establishing bactericidal levels in the prophylaxis of group B Streptococcus","volume":"194","author":"Colombo","year":"2006","journal-title":"Am J Obstet Gynecol"},{"issue":"1","key":"10.1016\/j.yapd.2007.03.004_bib90","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1542\/peds.2005-0179","article-title":"Empiric use of ampicillin and cefotaxime, compared with ampicillin and gentamicin, for neonates at risk for sepsis is associated with an increased risk of neonatal death","volume":"117","author":"Clark","year":"2006","journal-title":"Pediatrics"},{"issue":"2","key":"10.1016\/j.yapd.2007.03.004_bib91","doi-asserted-by":"crossref","first-page":"162","DOI":"10.1016\/j.jpeds.2005.02.020","article-title":"Fluconazole prophylaxis prevents invasive fungal infection in high-risk, very low birth weight infants","volume":"147","author":"Bertini","year":"2005","journal-title":"J Pediatr"},{"issue":"3 Pt 2","key":"10.1016\/j.yapd.2007.03.004_bib92","doi-asserted-by":"crossref","first-page":"S9","DOI":"10.1542\/peds.2005-0620C","article-title":"Summary proceedings from the neonatal pain-control group","volume":"117","author":"Anand","year":"2006","journal-title":"Pediatrics"},{"issue":"6","key":"10.1016\/j.yapd.2007.03.004_bib93","doi-asserted-by":"crossref","first-page":"877","DOI":"10.1016\/j.clinthera.2005.06.019","article-title":"Analgesia and sedation during mechanical ventilation in neonates","volume":"27","author":"Aranda","year":"2005","journal-title":"Clin Ther"},{"issue":"2","key":"10.1016\/j.yapd.2007.03.004_bib94","doi-asserted-by":"crossref","first-page":"352","DOI":"10.1542\/peds.2004-2123","article-title":"Morphine administration and short-term pulmonary outcomes among ventilated preterm infants","volume":"116","author":"Bhandari","year":"2005","journal-title":"Pediatrics"},{"issue":"6","key":"10.1016\/j.yapd.2007.03.004_bib95","doi-asserted-by":"crossref","first-page":"844","DOI":"10.1016\/j.clinthera.2005.06.018","article-title":"Analgesia and local anesthesia during invasive procedures in the neonate","volume":"27","author":"Anand","year":"2005","journal-title":"Clin Ther"},{"issue":"6","key":"10.1016\/j.yapd.2007.03.004_bib96","doi-asserted-by":"crossref","first-page":"1494","DOI":"10.1542\/peds.2004-1425","article-title":"Morphine does not provide adequate analgesia for acute procedural pain among preterm neonates","volume":"115","author":"Carbajal","year":"2005","journal-title":"Pediatrics"},{"issue":"7","key":"10.1016\/j.yapd.2007.03.004_bib97","doi-asserted-by":"crossref","first-page":"793","DOI":"10.1001\/jama.295.7.793","article-title":"Intravenous morphine and topical tetracaine for treatment of pain in [corrected] neonates undergoing central line placement","volume":"295","author":"Taddio","year":"2006","journal-title":"JAMA"},{"issue":"2","key":"10.1016\/j.yapd.2007.03.004_bib98","doi-asserted-by":"crossref","first-page":"e137","DOI":"10.1542\/peds.2005-1543","article-title":"Association of H2-blocker therapy and higher incidence of necrotizing enterocolitis in very low birth weight infants","volume":"117","author":"Guillet","year":"2006","journal-title":"Pediatrics"},{"issue":"9458","key":"10.1016\/j.yapd.2007.03.004_bib99","doi-asserted-by":"crossref","first-page":"482","DOI":"10.1016\/S0140-6736(05)17865-9","article-title":"Selective serotonin reuptake inhibitors in pregnant women and neonatal withdrawal syndrome: a database analysis","volume":"365","author":"Sanz","year":"2005","journal-title":"Lancet"},{"issue":"2","key":"10.1016\/j.yapd.2007.03.004_bib100","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1001\/archpedi.160.2.173","article-title":"Neonatal abstinence syndrome after in utero exposure to selective serotonin reuptake inhibitors in term infants","volume":"160","author":"Levinson-Castiel","year":"2006","journal-title":"Arch Pediatr Adolesc Med"},{"issue":"19","key":"10.1016\/j.yapd.2007.03.004_bib101","doi-asserted-by":"crossref","first-page":"2372","DOI":"10.1001\/jama.293.19.2372","article-title":"Neonatal signs after late in utero exposure to serotonin reuptake inhibitors: literature review and implications for clinical applications","volume":"293","author":"Moses-Kolko","year":"2005","journal-title":"JAMA"},{"issue":"2","key":"10.1016\/j.yapd.2007.03.004_bib102","doi-asserted-by":"crossref","first-page":"411","DOI":"10.1542\/peds.2004-0420","article-title":"Pain reactivity in 2-month-old infants after prenatal and postnatal serotonin reuptake inhibitor medication exposure","volume":"115","author":"Oberlander","year":"2005","journal-title":"Pediatrics"},{"issue":"6","key":"10.1016\/j.yapd.2007.03.004_bib103","doi-asserted-by":"crossref","first-page":"579","DOI":"10.1056\/NEJMoa052744","article-title":"Selective serotonin-reuptake inhibitors and risk of persistent pulmonary hypertension of the newborn","volume":"354","author":"Chambers","year":"2006","journal-title":"N Engl J Med"},{"issue":"23","key":"10.1016\/j.yapd.2007.03.004_bib104","doi-asserted-by":"crossref","first-page":"2443","DOI":"10.1056\/NEJMoa055202","article-title":"Major congenital malformations after first-trimester exposure to ACE inhibitors","volume":"354","author":"Cooper","year":"2006","journal-title":"N Engl J Med"},{"issue":"10","key":"10.1016\/j.yapd.2007.03.004_bib105","doi-asserted-by":"crossref","first-page":"957","DOI":"10.1001\/archpedi.159.10.957","article-title":"Maternal progestin intake and risk of hypospadias","volume":"159","author":"Carmichael","year":"2005","journal-title":"Arch Pediatr Adolesc Med"},{"issue":"6","key":"10.1016\/j.yapd.2007.03.004_bib106","doi-asserted-by":"crossref","first-page":"549","DOI":"10.1016\/j.clpt.2006.02.010","article-title":"Pharmacokinetics of midazolam, propofol, and fentanyl transfer to human breast milk","volume":"79","author":"Nitsun","year":"2006","journal-title":"Clin Pharmacol Ther"},{"issue":"10","key":"10.1016\/j.yapd.2007.03.004_bib107","doi-asserted-by":"crossref","first-page":"943","DOI":"10.1001\/archpedi.159.10.943","article-title":"Association of amoxicillin use during early childhood with developmental tooth enamel defects","volume":"159","author":"Hong","year":"2005","journal-title":"Arch Pediatr Adolesc Med"},{"issue":"1","key":"10.1016\/j.yapd.2007.03.004_bib108","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1080\/15563650500394571","article-title":"Acetaminophen poisoning: an evidence-based consensus guideline for out-of-hospital management","volume":"44","author":"Dart","year":"2006","journal-title":"Clin Toxicol (Phila)"},{"issue":"12","key":"10.1016\/j.yapd.2007.03.004_bib109","doi-asserted-by":"crossref","first-page":"678","DOI":"10.1111\/j.1440-1754.2004.00491.x","article-title":"Clonidine poisoning in children: a recent experience","volume":"40","author":"Sinha","year":"2004","journal-title":"J Paediatr Child Health"},{"issue":"2","key":"10.1016\/j.yapd.2007.03.004_bib110","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1016\/j.jpeds.2004.09.027","article-title":"Toxic clonidine ingestion in children","volume":"146","author":"Spiller","year":"2005","journal-title":"J\u00a0Pediatr"}],"container-title":["Advances in Pediatrics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0065310107000059?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0065310107000059?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,24]],"date-time":"2025-09-24T20:06:35Z","timestamp":1758744395000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0065310107000059"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007]]},"references-count":110,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2007]]}},"alternative-id":["S0065310107000059"],"URL":"https:\/\/doi.org\/10.1016\/j.yapd.2007.03.004","relation":{},"ISSN":["0065-3101"],"issn-type":[{"type":"print","value":"0065-3101"}],"subject":[],"published":{"date-parts":[[2007]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Advances in Pediatric Pharmacology, Therapeutics, and Toxicology","name":"articletitle","label":"Article Title"},{"value":"Advances in Pediatrics","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.yapd.2007.03.004","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2007 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}