{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T01:39:26Z","timestamp":1791164366796,"version":"4.1.0"},"reference-count":75,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2004,6,1]],"date-time":"2004-06-01T00:00:00Z","timestamp":1086048000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2004,6,1]],"date-time":"2004-06-01T00:00:00Z","timestamp":1086048000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2013,7,17]],"date-time":"2013-07-17T00:00:00Z","timestamp":1374019200000},"content-version":"vor","delay-in-days":3333,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/501100001700","name":"Ministry of Education, Culture, Sports, Science and Technology","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001700","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004085","name":"Ministry of Education, Science and Technology","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004085","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001691","name":"Japan Society for the Promotion of Science","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001691","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Developmental Biology"],"published-print":{"date-parts":[[2004,6]]},"DOI":"10.1016\/j.ydbio.2004.02.017","type":"journal-article","created":{"date-parts":[[2004,4,13]],"date-time":"2004-04-13T05:30:59Z","timestamp":1081834259000},"page":"146-162","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":109,"title":["Mouse Zic5 deficiency results in neural tube defects and hypoplasia of cephalic neural crest derivatives"],"prefix":"10.1016","volume":"270","author":[{"given":"Takashi","family":"Inoue","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Minoru","family":"Hatayama","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takahide","family":"Tohmonda","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shigeyoshi","family":"Itohara","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jun","family":"Aruga","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katsuhiko","family":"Mikoshiba","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.ydbio.2004.02.017_BIB77","doi-asserted-by":"crossref","DOI":"10.1016\/j.mcn.2004.01.004","article-title":"The role of Zic genes in neural development","author":"Aruga","year":"2004","journal-title":"Mol. Cell. Neurosci."},{"key":"10.1016\/j.ydbio.2004.02.017_BIB1","doi-asserted-by":"crossref","first-page":"1180","DOI":"10.1046\/j.1471-4159.1994.63051880.x","article-title":"A novel zinc finger protein, Zic, is involved in neurogenesis, especially in the cell lineage of cerebellar granule cells","volume":"63","author":"Aruga","year":"1994","journal-title":"J. Neurochem."},{"key":"10.1016\/j.ydbio.2004.02.017_BIB2","doi-asserted-by":"crossref","first-page":"1043","DOI":"10.1074\/jbc.271.2.1043","article-title":"The mouse Zic gene family. Homologues of the Drosophila pair-rule gene odd-paired","volume":"271","author":"Aruga","year":"1996","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.ydbio.2004.02.017_BIB3","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1016\/0378-1119(96)00111-4","article-title":"Identification and characterization of Zic4, a new member of the mouse Zic gene family","volume":"172","author":"Aruga","year":"1996","journal-title":"Gene"},{"key":"10.1016\/j.ydbio.2004.02.017_BIB4","doi-asserted-by":"crossref","first-page":"284","DOI":"10.1523\/JNEUROSCI.18-01-00284.1998","article-title":"Mouse Zic1 is involved in cerebellar development","volume":"18","author":"Aruga","year":"1998","journal-title":"J. Neurosci."},{"key":"10.1016\/j.ydbio.2004.02.017_BIB5","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1016\/S0925-4773(99)00220-8","article-title":"Zic1 regulates the patterning of vertebral arches in cooperation with Gli3","volume":"89","author":"Aruga","year":"1999","journal-title":"Mech. Dev."},{"key":"10.1016\/j.ydbio.2004.02.017_BIB6","doi-asserted-by":"crossref","first-page":"218","DOI":"10.1523\/JNEUROSCI.22-01-00218.2002","article-title":"Zic2 controls cerebellar development in cooperation with Zic1","volume":"22","author":"Aruga","year":"2002","journal-title":"J. Neurosci."},{"key":"10.1016\/j.ydbio.2004.02.017_BIB7","doi-asserted-by":"crossref","first-page":"329","DOI":"10.1006\/dbio.2002.0598","article-title":"Zic1 promotes the expansion of dorsal neural progenitors in spinal cord by inhibiting neuronal differentiation","volume":"244","author":"Aruga","year":"2002","journal-title":"Dev. Biol."},{"key":"10.1016\/j.ydbio.2004.02.017_BIB8","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1101\/gad.8.1.105","article-title":"odd-paired: a zinc finger pair-rule protein required for the timely activation of engrailed and wingless in Drosophila embryos","volume":"8","author":"Benedyk","year":"1994","journal-title":"Genes Dev."},{"key":"10.1016\/j.ydbio.2004.02.017_BIB9","doi-asserted-by":"crossref","first-page":"2029","DOI":"10.1101\/gad.11.16.2029","article-title":"Mice lacking the ski proto-oncogene have defects in neurulation, craniofacial patterning, and skeletal muscle development","volume":"11","author":"Berk","year":"1997","journal-title":"Genes Dev."},{"key":"10.1016\/j.ydbio.2004.02.017_BIB10","doi-asserted-by":"crossref","first-page":"579","DOI":"10.1038\/31242","article-title":"Gli\/Zic factors pattern the neural plate by defining domains of cell differentiation","volume":"393","author":"Brewster","year":"1998","journal-title":"Nature"},{"key":"10.1016\/j.ydbio.2004.02.017_BIB11","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1101\/gad.186601","article-title":"The transcription factor Sox10 is a key regulator of peripheral glial development","volume":"15","author":"Britsch","year":"2001","journal-title":"Genes Dev."},{"key":"10.1016\/j.ydbio.2004.02.017_BIB12","doi-asserted-by":"crossref","first-page":"52","DOI":"10.1002\/ajmg.1320450115","article-title":"Preliminary definition of a \u201ccritical region\u201d: of chromosome 13 in q32: report of 14 cases with 13q deletion and review of the literature","volume":"45","author":"Brown","year":"1993","journal-title":"Am. J. Med. Genet."},{"key":"10.1016\/j.ydbio.2004.02.017_BIB13","first-page":"859","article-title":"The 13q-syndrome: the molecular definition of a critical deletion region in band 13q32","volume":"57","author":"Brown","year":"1995","journal-title":"Am. J. Hum. Genet."},{"key":"10.1016\/j.ydbio.2004.02.017_BIB14","doi-asserted-by":"crossref","first-page":"180","DOI":"10.1038\/2484","article-title":"Holoprosencephaly due to mutations in ZIC2, a homologue of Drosophila odd-paired","volume":"20","author":"Brown","year":"1998","journal-title":"Nat. Genet."},{"key":"10.1016\/j.ydbio.2004.02.017_BIB15","doi-asserted-by":"crossref","first-page":"791","DOI":"10.1093\/hmg\/10.8.791","article-title":"Holoprosencephaly due to mutations in ZIC2: alanine tract expansion mutations may be caused by parental somatic recombination","volume":"10","author":"Brown","year":"2001","journal-title":"Hum. Mol. Genet."},{"key":"10.1016\/j.ydbio.2004.02.017_BIB16","doi-asserted-by":"crossref","first-page":"128","DOI":"10.1002\/ajmg.10221","article-title":"Possible association of NTDs with a polyhistidine tract polymorphism in the ZIC2 gene","volume":"108","author":"Brown","year":"2002","journal-title":"Am. J. Med. Genet."},{"key":"10.1016\/j.ydbio.2004.02.017_BIB17","doi-asserted-by":"crossref","first-page":"1937","DOI":"10.1093\/hmg\/9.13.1937","article-title":"The X-linked mouse mutation Bent tail is associated with a deletion of the Zic3 locus","volume":"9","author":"Carrel","year":"2000","journal-title":"Hum. Mol. Genet."},{"key":"10.1016\/j.ydbio.2004.02.017_BIB18","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1006\/dbio.1997.8820","article-title":"A neural crest induction by Xwnt7b in Xenopus","volume":"194","author":"Chang","year":"1998","journal-title":"Dev. Biol."},{"key":"10.1016\/j.ydbio.2004.02.017_BIB19","doi-asserted-by":"crossref","first-page":"686","DOI":"10.1101\/gad.9.6.686","article-title":"twist is required in head mesenchyme for cranial neural tube morphogenesis","volume":"9","author":"Chen","year":"1995","journal-title":"Genes Dev."},{"key":"10.1016\/j.ydbio.2004.02.017_BIB20","doi-asserted-by":"crossref","first-page":"363","DOI":"10.1016\/0301-0082(90)90037-H","article-title":"The embryonic development of mammalian neural tube defects","volume":"35","author":"Copp","year":"1990","journal-title":"Prog. Neurobiol."},{"key":"10.1016\/j.ydbio.2004.02.017_BIB21","doi-asserted-by":"crossref","first-page":"2873","DOI":"10.1242\/dev.127.13.2873","article-title":"Delta signaling mediates segregation of neural crest and spinal sensory neurons from zebrafish lateral neural plate","volume":"127","author":"Cornell","year":"2000","journal-title":"Development"},{"key":"10.1016\/j.ydbio.2004.02.017_BIB23","doi-asserted-by":"crossref","first-page":"287","DOI":"10.1242\/dev.111.2.287","article-title":"Examining pattern formation in mice, chicken and frog embryos with an En-specific antiserum","volume":"111","author":"Davis","year":"1991","journal-title":"Development"},{"key":"10.1016\/j.ydbio.2004.02.017_BIB24","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1006\/dbio.2002.0756","article-title":"Disruption of segmental neural crest migration and Ephrin expression in Delta-1 null mice","volume":"249","author":"De Bellard","year":"2002","journal-title":"Dev. Biol."},{"key":"10.1016\/j.ydbio.2004.02.017_BIB25","doi-asserted-by":"crossref","first-page":"391","DOI":"10.1016\/j.ydbio.2003.09.005","article-title":"Zic2 is required for neural crest formation and hindbrain patterning during mouse development","volume":"264","author":"Elms","year":"2003","journal-title":"Dev. Biol."},{"key":"10.1016\/j.ydbio.2004.02.017_BIB26","doi-asserted-by":"crossref","first-page":"863","DOI":"10.1242\/dev.129.4.863","article-title":"Bimodal functions of Notch-mediated signaling are involved in neural crest formation during avian ectoderm development","volume":"129","author":"Endo","year":"2002","journal-title":"Development"},{"key":"10.1016\/j.ydbio.2004.02.017_BIB27","doi-asserted-by":"crossref","first-page":"575","DOI":"10.1093\/hmg\/9.4.575","article-title":"A genetic risk factor for mouse neural tube defects: defining the embryonic basis","volume":"9","author":"Fleming","year":"2000","journal-title":"Hum. Mol. Genet."},{"key":"10.1016\/j.ydbio.2004.02.017_BIB29","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1007\/s00429-003-0345-2","article-title":"Analysis for the embryonic phenotype of Bent tail, a mouse model for X-linked neural tube defects","volume":"207","author":"Franke","year":"2003","journal-title":"Anat. Embryol."},{"key":"10.1016\/j.ydbio.2004.02.017_BIB28","first-page":"236","article-title":"Primary structure and functional expression of the inositol 1,4,5-trisphosphate binding protein P400","volume":"340","author":"Furuichi","year":"1989","journal-title":"Nature"},{"key":"10.1016\/j.ydbio.2004.02.017_BIB30","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1016\/S0925-4773(00)00456-1","article-title":"A new murine zinc finger gene, opr","volume":"98","author":"Furushima","year":"2000","journal-title":"Mech. Dev."},{"key":"10.1016\/j.ydbio.2004.02.017_BIB31","doi-asserted-by":"crossref","first-page":"795","DOI":"10.1038\/nrn1219","article-title":"Neural crest specification: migrating into genomics","volume":"4","author":"Gammill","year":"2003","journal-title":"Nat. Rev. Neurosci."},{"key":"10.1016\/j.ydbio.2004.02.017_BIB32","doi-asserted-by":"crossref","first-page":"848","DOI":"10.1126\/science.1070824","article-title":"Ectodermal Wnt function as a neural crest inducer","volume":"297","author":"Garc\u0131\u0301a-Castro","year":"2002","journal-title":"Science"},{"key":"10.1016\/j.ydbio.2004.02.017_BIB33","doi-asserted-by":"crossref","first-page":"305","DOI":"10.1038\/ng1197-305","article-title":"X-linked situs abnormalities result from mutations in ZIC3","volume":"17","author":"Gebbia","year":"1997","journal-title":"Nat. Genet."},{"key":"10.1016\/j.ydbio.2004.02.017_BIB34","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1016\/0896-6273(95)90238-4","article-title":"Mice devoid of the glial fibrillary acidic protein develop normally and are susceptible to scrapie prions","volume":"14","author":"Gomi","year":"1995","journal-title":"Neuron"},{"key":"10.1016\/j.ydbio.2004.02.017_BIB35","doi-asserted-by":"crossref","first-page":"292","DOI":"10.1002\/(SICI)1096-9926(199911)60:5<292::AID-TERA10>3.0.CO;2-6","article-title":"Mini-review: toward understanding mechanisms of genetic neural tube defects in mice","volume":"60","author":"Harris","year":"1999","journal-title":"Teratology"},{"key":"10.1016\/j.ydbio.2004.02.017_BIB36","series-title":"Manipulating the Mouse Embryo","first-page":"379","article-title":"Staining embryos for cartilage and bone","author":"Hogan","year":"1994"},{"key":"10.1016\/j.ydbio.2004.02.017_BIB37","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1016\/0925-4773(95)00385-E","article-title":"Wnt expression patterns in chick embryo nervous system","volume":"52","author":"Hollyday","year":"1995","journal-title":"Mech. Dev."},{"key":"10.1016\/j.ydbio.2004.02.017_BIB38","doi-asserted-by":"crossref","first-page":"402","DOI":"10.1006\/dbio.1994.1097","article-title":"Expression of three mouse homologs of the Drosophila segment polarity gene cubitus interruptus, Gli, Gli-2, and Gli-3, in ectoderm and mesoderm-derived tissues suggests multiple roles during postimplantation development","volume":"162","author":"Hui","year":"1995","journal-title":"Dev. Biol."},{"key":"10.1016\/j.ydbio.2004.02.017_BIB39","doi-asserted-by":"crossref","first-page":"966","DOI":"10.1038\/40146","article-title":"Wnt signaling required for expansion of neural crest and CNS projenitors","volume":"389","author":"Ikeya","year":"1997","journal-title":"Nature"},{"key":"10.1016\/j.ydbio.2004.02.017_BIB40","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1006\/dbio.1996.8501","article-title":"Cadherin-6 expression transiently delineates specific rhombomeres, other neural tube subdivisions, and neural crest subpopulations in mouse embryos","volume":"183","author":"Inoue","year":"1997","journal-title":"Dev. Biol."},{"key":"10.1016\/j.ydbio.2004.02.017_BIB41","doi-asserted-by":"crossref","first-page":"3136","DOI":"10.1101\/gad.9.24.3136","article-title":"Targeted disruption of mammalian hairy and Enhancer od split homolog-1 (HES-1) leads to up-regulation of neural helics-loop-helics factors, premature neurogenesis, and severe neural tube defects","volume":"9","author":"Ishibashi","year":"1995","journal-title":"Genes Dev."},{"key":"10.1016\/j.ydbio.2004.02.017_BIB42","doi-asserted-by":"crossref","first-page":"993","DOI":"10.1093\/hmg\/9.6.993","article-title":"Mouse models for neural tube closure defects","volume":"9","author":"Juriloff","year":"2000","journal-title":"Hum. Mol. Genet."},{"key":"10.1016\/j.ydbio.2004.02.017_BIB43","doi-asserted-by":"crossref","first-page":"1615","DOI":"10.1093\/hmg\/9.11.1615","article-title":"A deletion encompassing Zic3 in Bent tail, a mouse model for X-linked neural tube defects","volume":"9","author":"Klootwijk","year":"2000","journal-title":"Hum. Mol. Genet."},{"key":"10.1016\/j.ydbio.2004.02.017_BIB44","doi-asserted-by":"crossref","first-page":"6889","DOI":"10.1074\/jbc.C000773200","article-title":"Physical and functional interactions between Zic and Gli proteins","volume":"276","author":"Koyabu","year":"2001","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.ydbio.2004.02.017_BIB45","doi-asserted-by":"crossref","first-page":"667","DOI":"10.1016\/S0896-6273(00)80727-8","article-title":"The Jnk1 and Jnk2 protein kinases are required for regional specific apoptosis during early brain development","volume":"22","author":"Kuan","year":"1999","journal-title":"Neuron"},{"key":"10.1016\/j.ydbio.2004.02.017_BIB46","doi-asserted-by":"crossref","first-page":"2867","DOI":"10.1242\/dev.125.15.2867","article-title":"Opl: a zinc finger protein that regulates neural determination and patterning in Xenopus","volume":"125","author":"Kuo","year":"1998","journal-title":"Development"},{"key":"10.1016\/j.ydbio.2004.02.017_BIB47","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1146\/annurev.cellbio.15.1.81","article-title":"Molecular mechanisms of neural crest formation","volume":"15","author":"LaBonne","year":"1999","journal-title":"Annu. Rev. Cell Dev. Biol."},{"key":"10.1016\/j.ydbio.2004.02.017_BIB48","article-title":"Developmental and Cell Biology Series","volume":"vol. 12","author":"Le Douarin","year":"1982"},{"key":"10.1016\/j.ydbio.2004.02.017_BIB50","doi-asserted-by":"crossref","first-page":"767","DOI":"10.1242\/dev.121.3.767","article-title":"Induction of the prospective neural crest of Xenopus","volume":"121","author":"Mayer","year":"1995","journal-title":"Development"},{"key":"10.1016\/j.ydbio.2004.02.017_BIB51","doi-asserted-by":"crossref","first-page":"1017","DOI":"10.1086\/344412","article-title":"Multiple hits during early embryonic development: digenic diseases and holoprosencephaly","volume":"71","author":"Ming","year":"2002","journal-title":"Am. J. Hum. Genet."},{"key":"10.1016\/j.ydbio.2004.02.017_BIB52","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1101\/gad.5.1.105","article-title":"Transcription factor AP-2 is expressed in neural crest lineages during mouse embryogenesis","volume":"5","author":"Mitchell","year":"1991","journal-title":"Genes Dev."},{"key":"10.1016\/j.ydbio.2004.02.017_BIB53","doi-asserted-by":"crossref","first-page":"2180","DOI":"10.1074\/jbc.M004430200","article-title":"Molecular properties of Zic proteins as transcriptional regulators and their relationship to GLI proteins","volume":"276","author":"Mizugishi","year":"2001","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.ydbio.2004.02.017_BIB54","doi-asserted-by":"crossref","first-page":"579","DOI":"10.1242\/dev.125.4.579","article-title":"Xenopus Zic-relaterd-1 and Sox2, two factors induced by chordin, have distinct activities in the initiation of neural induction","volume":"125","author":"Mizuseki","year":"1998","journal-title":"Development"},{"key":"10.1016\/j.ydbio.2004.02.017_BIB55","doi-asserted-by":"crossref","first-page":"1053","DOI":"10.1242\/dev.112.4.1053","article-title":"The Msh-like homeobox genes define domains in the developing vertebrate eye","volume":"112","author":"Monaghan","year":"1991","journal-title":"Development"},{"key":"10.1016\/j.ydbio.2004.02.017_BIB56","doi-asserted-by":"crossref","first-page":"299","DOI":"10.1006\/dbio.1996.8449","article-title":"The expression of the mouse Zic1, Zic2 and Zic3 gene suggests an essential role for Zic genes in body pattern formation","volume":"182","author":"Nagai","year":"1997","journal-title":"Dev. Biol."},{"key":"10.1016\/j.ydbio.2004.02.017_BIB57","doi-asserted-by":"crossref","first-page":"1618","DOI":"10.1073\/pnas.97.4.1618","article-title":"Zic2 regulates the kinetics of neurulation","volume":"97","author":"Nagai","year":"2000","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.ydbio.2004.02.017_BIB58","doi-asserted-by":"crossref","first-page":"11980","DOI":"10.1073\/pnas.94.22.11980","article-title":"Xenopus Zic3, a primary regulator both in neural and neural crest development","volume":"94","author":"Nakata","year":"1997","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.ydbio.2004.02.017_BIB59","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1016\/S0925-4773(98)00073-2","article-title":"Xenopus Zic family and its role in neural and neural crest development","volume":"75","author":"Nakata","year":"1998","journal-title":"Mech. Dev."},{"key":"10.1016\/j.ydbio.2004.02.017_BIB60","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1016\/S0925-4773(00)00480-9","article-title":"A novel member of the Xenopus Zic family, Zic5, mediates neural crest development","volume":"99","author":"Nakata","year":"2000","journal-title":"Mech. Dev."},{"key":"10.1016\/j.ydbio.2004.02.017_BIB61","series-title":"Normal Table of Xenopus leavis (Daudin)","author":"Nieuwkoop","year":"1967"},{"key":"10.1016\/j.ydbio.2004.02.017_BIB62","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/s004390100537","article-title":"Identification of novel mutations in SHH and ZIC2 in a South American (ECLAMC) population with holoprosencephaly","volume":"109","author":"Orioli","year":"2001","journal-title":"Hum. Genet."},{"key":"10.1016\/j.ydbio.2004.02.017_BIB63","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1242\/dev.119.1.247","article-title":"Mouse Wnt genes exhibit discrete domains of expression in the early embryonic CNS and limb buds","volume":"119","author":"Parr","year":"1993","journal-title":"Development"},{"key":"10.1016\/j.ydbio.2004.02.017_BIB64","doi-asserted-by":"crossref","first-page":"2293","DOI":"10.1242\/dev.129.9.2293","article-title":"A complex syndrome of left\u2013right axis, central nervous system and axial skeleton defects in Zic3 mutant mice","volume":"129","author":"Purandare","year":"2002","journal-title":"Development"},{"key":"10.1016\/j.ydbio.2004.02.017_BIB65","doi-asserted-by":"crossref","first-page":"383","DOI":"10.1016\/0092-8674(92)90508-A","article-title":"Inactivation of MyoD in mice leads to up-regulation of the myogenic HLH gene Myf-5 and results in apparently normal muscle development","volume":"71","author":"Rudnicki","year":"1992","journal-title":"Cell"},{"key":"10.1016\/j.ydbio.2004.02.017_BIB66","first-page":"3104","article-title":"The GLI-Kruppel family of human genes","volume":"8","author":"Ruppert","year":"1988","journal-title":"Mol. Cell. Biol."},{"key":"10.1016\/j.ydbio.2004.02.017_BIB67","doi-asserted-by":"crossref","first-page":"13713","DOI":"10.1073\/pnas.94.25.13713","article-title":"Regulation of dorsal fate in the neuraxis by Wnt-1 and Wnt-3a","volume":"94","author":"Saint-Jeannet","year":"1997","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.ydbio.2004.02.017_BIB68","doi-asserted-by":"crossref","first-page":"318","DOI":"10.1006\/bbrc.1997.7111","article-title":"A transgenic mouse line that retains Cre recombinase activity in mature oocytes irrespective of the cre transgene transmission","volume":"273","author":"Sakai","year":"1997","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.ydbio.2004.02.017_BIB69","doi-asserted-by":"crossref","first-page":"174","DOI":"10.1101\/gad.8.2.174","article-title":"Wnt-3a regulates somite and tailbud formation in the mouse embryo","volume":"8","author":"Takada","year":"1994","journal-title":"Genes Dev."},{"key":"10.1016\/j.ydbio.2004.02.017_BIB70","doi-asserted-by":"crossref","first-page":"3665","DOI":"10.1242\/dev.128.19.3665","article-title":"Kermit, a frizzled interacting protein, regulates frizzled 3 signaling in neural crest development","volume":"128","author":"Tan","year":"2001","journal-title":"Development"},{"key":"10.1016\/j.ydbio.2004.02.017_BIB71","doi-asserted-by":"crossref","first-page":"1434","DOI":"10.1101\/gad.8.12.1434","article-title":"Expression of achaete-scute homolog3 in Xenopus embryos converts ectodermal cells to a neural fate","volume":"8","author":"Turner","year":"1994","journal-title":"Genes Dev."},{"key":"10.1016\/j.ydbio.2004.02.017_BIB72","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1006\/abio.1993.1459","article-title":"A novel negative selection for homologous recombinants using diphtheria toxin A fragment gene","volume":"214","author":"Yagi","year":"1993","journal-title":"Anal. Biochem."},{"key":"10.1016\/j.ydbio.2004.02.017_BIB73","doi-asserted-by":"crossref","first-page":"361","DOI":"10.1016\/S0092-8674(00)81165-4","article-title":"Gene dosage-dependent embryonic development and proliferation defects in mice lacking the transcriptional integrator p300","volume":"93","author":"Yao","year":"1998","journal-title":"Cell"},{"key":"10.1016\/j.ydbio.2004.02.017_BIB74","series-title":"In situ Hybridization, A Practical Approach","first-page":"75","article-title":"Whole mount in situ hybridization of vertebrate embryos","author":"Wilkinson","year":"1992"},{"key":"10.1016\/j.ydbio.2004.02.017_BIB75","doi-asserted-by":"crossref","first-page":"363","DOI":"10.1016\/0012-1606(91)90086-I","article-title":"The M-twist gene of Mus is expressed in subsets of mesodermal cells and is closely related to the Xenopus X-twi and Drosophila twist genes","volume":"143","author":"Wolf","year":"1991","journal-title":"Dev. Biol."},{"key":"10.1016\/j.ydbio.2004.02.017_BIB76","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1038\/ng0796-275","article-title":"Prenatal folic acid treatment suppresses acrania and meroanencephaly in mice mutant for Cart1 homeobox gene","volume":"13","author":"Zhao","year":"1996","journal-title":"Nat. Genet."}],"container-title":["Developmental Biology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0012160604001368?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0012160604001368?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,2]],"date-time":"2025-11-02T22:46:21Z","timestamp":1762123581000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0012160604001368"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2004,6]]},"references-count":75,"aliases":["10.1016\/s0012-1606(04)00136-8"],"journal-issue":{"issue":"1","published-print":{"date-parts":[[2004,6]]}},"alternative-id":["S0012160604001368"],"URL":"https:\/\/doi.org\/10.1016\/j.ydbio.2004.02.017","relation":{},"ISSN":["0012-1606"],"issn-type":[{"value":"0012-1606","type":"print"}],"subject":[],"published":{"date-parts":[[2004,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Mouse Zic5 deficiency results in neural tube defects and hypoplasia of cephalic neural crest derivatives","name":"articletitle","label":"Article Title"},{"value":"Developmental Biology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ydbio.2004.02.017","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"converted-article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2004 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}