{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,3]],"date-time":"2026-10-03T22:21:20Z","timestamp":1791066080010,"version":"4.1.0"},"reference-count":24,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2006,1,1]],"date-time":"2006-01-01T00:00:00Z","timestamp":1136073600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2013,7,17]],"date-time":"2013-07-17T00:00:00Z","timestamp":1374019200000},"content-version":"vor","delay-in-days":2754,"URL":"https:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Developmental Biology"],"published-print":{"date-parts":[[2006,1]]},"DOI":"10.1016\/j.ydbio.2005.11.008","type":"journal-article","created":{"date-parts":[[2005,12,6]],"date-time":"2005-12-06T12:20:52Z","timestamp":1133871652000},"page":"420-429","source":"Crossref","is-referenced-by-count":87,"title":["Cardiovascular malformations with normal smooth muscle differentiation in neural crest-specific type II TGF\u03b2 receptor (Tgfbr2) mutant mice"],"prefix":"10.1016","volume":"289","author":[{"given":"Bibha","family":"Choudhary","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yoshihiro","family":"Ito","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takako","family":"Makita","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tomoyo","family":"Sasaki","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yang","family":"Chai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Henry M.","family":"Sucov","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.ydbio.2005.11.008_bib1","doi-asserted-by":"crossref","first-page":"4567","DOI":"10.1242\/dev.00673","article-title":"Dissimilar regulation of cell differentiation in mesencephalic (cranial) and sacral (trunk) neural crest cells in vitro","volume":"130","author":"Abzhanov","year":"2003","journal-title":"Development"},{"key":"10.1016\/j.ydbio.2005.11.008_bib2","doi-asserted-by":"crossref","first-page":"2745","DOI":"10.1161\/01.CIR.103.22.2745","article-title":"Double-outlet right ventricle and overriding tricuspid valve reflect disturbances of looping, myocardialization, endocardial cushion differentiation, and apoptosis in TGF-beta(2)-knockout mice","volume":"103","author":"Bartram","year":"2001","journal-title":"Circulation"},{"key":"10.1016\/j.ydbio.2005.11.008_bib3","doi-asserted-by":"crossref","first-page":"1671","DOI":"10.1242\/dev.127.8.1671","article-title":"Fate of the mammalian cranial neural crest during tooth and mandibular morphogenesis","volume":"127","author":"Chai","year":"2000","journal-title":"Development"},{"key":"10.1016\/j.ydbio.2005.11.008_bib4","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1002\/gene.10046","article-title":"Conditional inactivation of the TGF-beta type II receptor using Cre:Lox","volume":"32","author":"Chytil","year":"2002","journal-title":"Genesis"},{"key":"10.1016\/j.ydbio.2005.11.008_bib5","doi-asserted-by":"crossref","first-page":"2675","DOI":"10.1006\/jmcc.1997.0499","article-title":"Neural crest is involved in development of abnormal myocardial function","volume":"29","author":"Conway","year":"1997","journal-title":"J. Mol. Cell. Cardiol."},{"key":"10.1016\/j.ydbio.2005.11.008_bib6","doi-asserted-by":"crossref","first-page":"1323","DOI":"10.1016\/S0960-9822(07)00562-3","article-title":"Modification of gene activity in mouse embryos in utero by a tamoxifen-inducible form of Cre recombinase","volume":"8","author":"Danielian","year":"1998","journal-title":"Curr. Biol."},{"key":"10.1016\/j.ydbio.2005.11.008_bib7","doi-asserted-by":"crossref","first-page":"577","DOI":"10.1038\/nature02006","article-title":"Smad-dependent and Smad-independent pathways in TGF-beta family signalling","volume":"425","author":"Derynck","year":"2003","journal-title":"Nature"},{"key":"10.1016\/j.ydbio.2005.11.008_bib8","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1007\/s00429-002-0273-6","article-title":"Tgfbeta2 \u2212\/\u2212 Tgfbeta3 \u2212\/\u2212 double knockout mice display severe midline fusion defects and early embryonic lethality","volume":"206","author":"Dunker","year":"2002","journal-title":"Anat. Embryol. (Berl)"},{"key":"10.1016\/j.ydbio.2005.11.008_bib9","doi-asserted-by":"crossref","first-page":"1869","DOI":"10.1242\/dev.127.9.1869","article-title":"Migration of cardiac neural crest cells in Splotch embryos","volume":"127","author":"Epstein","year":"2000","journal-title":"Development"},{"key":"10.1016\/j.ydbio.2005.11.008_bib10","doi-asserted-by":"crossref","first-page":"5269","DOI":"10.1242\/dev.00708","article-title":"Conditional inactivation of Tgfbr2 in cranial neural crest causes cleft palate and calvaria defects","volume":"130","author":"Ito","year":"2003","journal-title":"Development"},{"key":"10.1016\/j.ydbio.2005.11.008_bib11","doi-asserted-by":"crossref","first-page":"1607","DOI":"10.1242\/dev.127.8.1607","article-title":"Fate of the mammalian cardiac neural crest","volume":"127","author":"Jiang","year":"2000","journal-title":"Development"},{"key":"10.1016\/j.ydbio.2005.11.008_bib12","doi-asserted-by":"crossref","first-page":"3481","DOI":"10.1242\/dev.01214","article-title":"Cardiac outflow tract defects in mice lacking ALK2 in neural crest cells","volume":"131","author":"Kaartinen","year":"2004","journal-title":"Development"},{"key":"10.1016\/j.ydbio.2005.11.008_bib13","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1161\/01.RES.77.2.211","article-title":"Neural crest and cardiovascular patterning","volume":"77","author":"Kirby","year":"1995","journal-title":"Circ. Res."},{"key":"10.1016\/j.ydbio.2005.11.008_bib14","doi-asserted-by":"crossref","first-page":"1663","DOI":"10.1093\/emboj\/20.7.1663","article-title":"Abnormal angiogenesis but intact hematopoietic potential in TGF-beta type I receptor-deficient mice","volume":"20","author":"Larsson","year":"2001","journal-title":"EMBO J."},{"key":"10.1016\/j.ydbio.2005.11.008_bib15","series-title":"The Neural Crest","author":"LeDouarin","year":"1982"},{"key":"10.1016\/j.ydbio.2005.11.008_bib16","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1038\/35043051","article-title":"How cells read TGF-beta signals","volume":"1","author":"Massague","year":"2000","journal-title":"Nat. Rev., Mol. Cell Biol."},{"key":"10.1016\/j.ydbio.2005.11.008_bib17","doi-asserted-by":"crossref","first-page":"312","DOI":"10.1016\/S0008-6363(02)00542-4","article-title":"Altered apoptosis pattern during pharyngeal arch artery remodelling is associated with aortic arch malformations in Tgfbeta2 knock-out mice","volume":"56","author":"Molin","year":"2002","journal-title":"Cardiovasc. Res."},{"key":"10.1016\/j.ydbio.2005.11.008_bib18","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1006\/dbio.1996.0259","article-title":"TGF-beta receptor type II deficiency results in defects of yolk sac hematopoiesis and vasculogenesis","volume":"179","author":"Oshima","year":"1996","journal-title":"Dev. Biol."},{"key":"10.1016\/j.ydbio.2005.11.008_bib19","doi-asserted-by":"crossref","first-page":"2659","DOI":"10.1242\/dev.124.13.2659","article-title":"TGFb2 knockout mice have multiple developmental defects that are nonoverlapping with other TGFb knockout phenotypes","volume":"124","author":"Sanford","year":"1997","journal-title":"Development"},{"key":"10.1016\/j.ydbio.2005.11.008_bib20","doi-asserted-by":"crossref","first-page":"331","DOI":"10.1016\/S0092-8674(00)81112-5","article-title":"Alternative neural crest cell fates are instructively promoted by TGFbeta superfamily members","volume":"85","author":"Shah","year":"1996","journal-title":"Cell"},{"key":"10.1016\/j.ydbio.2005.11.008_bib21","doi-asserted-by":"crossref","first-page":"70","DOI":"10.1038\/5007","article-title":"Generalized lacZ expression with the ROSA26 Cre reporter strain","volume":"21","author":"Soriano","year":"1999","journal-title":"Nat. Genet."},{"key":"10.1016\/j.ydbio.2005.11.008_bib22","doi-asserted-by":"crossref","first-page":"507","DOI":"10.1242\/dev.00241","article-title":"Cell autonomous requirement for PDGFRalpha in populations of cranial and cardiac neural crest cells","volume":"130","author":"Tallquist","year":"2003","journal-title":"Development"},{"key":"10.1016\/j.ydbio.2005.11.008_bib23","doi-asserted-by":"crossref","first-page":"406","DOI":"10.1016\/0002-9149(65)90732-0","article-title":"The anatomy of common aorticopulmonary trunk (truncus arteriosus communis) and its embryologic implications","volume":"16","author":"van Praagh","year":"1965","journal-title":"Am. J. Cardiol."},{"key":"10.1016\/j.ydbio.2005.11.008_bib24","doi-asserted-by":"crossref","first-page":"530","DOI":"10.1101\/gad.317405","article-title":"Inactivation of TGFbeta signaling in neural crest stem cells leads to multiple defects reminiscent of DiGeorge syndrome","volume":"19","author":"Wurdak","year":"2005","journal-title":"Genes Dev."}],"container-title":["Developmental Biology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0012160605007827?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0012160605007827?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2021,7,21]],"date-time":"2021-07-21T01:30:53Z","timestamp":1626831053000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0012160605007827"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2006,1]]},"references-count":24,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2006,1]]}},"alternative-id":["S0012160605007827"],"URL":"https:\/\/doi.org\/10.1016\/j.ydbio.2005.11.008","relation":{},"ISSN":["0012-1606"],"issn-type":[{"value":"0012-1606","type":"print"}],"subject":[],"published":{"date-parts":[[2006,1]]}}}