{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,8]],"date-time":"2026-01-08T08:04:01Z","timestamp":1767859441980,"version":"3.49.0"},"reference-count":34,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2008,1,1]],"date-time":"2008-01-01T00:00:00Z","timestamp":1199145600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2008,1,1]],"date-time":"2008-01-01T00:00:00Z","timestamp":1199145600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2013,8,22]],"date-time":"2013-08-22T00:00:00Z","timestamp":1377129600000},"content-version":"vor","delay-in-days":2060,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"},{"start":{"date-parts":[[2008,1,1]],"date-time":"2008-01-01T00:00:00Z","timestamp":1199145600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2008,1,1]],"date-time":"2008-01-01T00:00:00Z","timestamp":1199145600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2008,1,1]],"date-time":"2008-01-01T00:00:00Z","timestamp":1199145600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2008,1,1]],"date-time":"2008-01-01T00:00:00Z","timestamp":1199145600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2008,1,1]],"date-time":"2008-01-01T00:00:00Z","timestamp":1199145600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Developmental Biology"],"published-print":{"date-parts":[[2008,1]]},"DOI":"10.1016\/j.ydbio.2007.10.013","type":"journal-article","created":{"date-parts":[[2007,10,24]],"date-time":"2007-10-24T07:17:19Z","timestamp":1193210239000},"page":"246-255","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":50,"title":["JAM-A is present in mammalian spermatozoa where it is essential for normal motility"],"prefix":"10.1016","volume":"313","author":[{"given":"Minghai","family":"Shao","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ananya","family":"Ghosh","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vesselina G.","family":"Cooke","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ulhas P.","family":"Naik","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Patricia A.","family":"Martin-DeLeon","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.ydbio.2007.10.013_bib1","doi-asserted-by":"crossref","first-page":"843","DOI":"10.1055\/s-0037-1613312","article-title":"F11-receptor (F11R\/JAM) mediates platelet adhesion to endothelial cells: role in inflammatory thrombosis","volume":"8","author":"Babinska","year":"2002","journal-title":"Thromb. Haemost."},{"key":"10.1016\/j.ydbio.2007.10.013_bib2","doi-asserted-by":"crossref","first-page":"441","DOI":"10.1016\/S0092-8674(01)00231-8","article-title":"Junction adhesion molecule is a receptor for reovirus","volume":"104","author":"Barton","year":"2001","journal-title":"Cell"},{"key":"10.1016\/j.ydbio.2007.10.013_bib3","doi-asserted-by":"crossref","first-page":"525","DOI":"10.1016\/S0955-0674(03)00104-2","article-title":"The JAM family of junctional adhesion molecules","volume":"15","author":"Bazzoni","year":"2003","journal-title":"Curr. Opin. Cell Biol."},{"key":"10.1016\/j.ydbio.2007.10.013_bib4","doi-asserted-by":"crossref","first-page":"30970","DOI":"10.1074\/jbc.M003946200","article-title":"Homophilic interaction of junctional adhesion molecule","volume":"275","author":"Bazzoni","year":"2000","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.ydbio.2007.10.013_bib5","doi-asserted-by":"crossref","first-page":"153","DOI":"10.3109\/01485018408987514","article-title":"Characterization of hyperactivated motility by human spermatozoa during capacitation: comparison of fertile and oligozoospermic sperm populations","volume":"13","author":"Burkman","year":"1984","journal-title":"Arch. Androl."},{"key":"10.1016\/j.ydbio.2007.10.013_bib6","doi-asserted-by":"crossref","first-page":"2582","DOI":"10.1128\/MCB.01722-06","article-title":"Abnormal sperm in mice lacking the Taf7l gene","volume":"27","author":"Cheng","year":"2007","journal-title":"Mol. Cell. Biol."},{"key":"10.1016\/j.ydbio.2007.10.013_bib7","doi-asserted-by":"crossref","first-page":"2005","DOI":"10.1161\/01.ATV.0000234923.79173.99","article-title":"Fibroblast growth factor-2 failed to induce angiogenesis in junctional adhesion molecule-a-deficient mice","volume":"26","author":"Cooke","year":"2006","journal-title":"Arterioscler. Thromb. Vasc. Biol."},{"key":"10.1016\/j.ydbio.2007.10.013_bib8","series-title":"Andrology: Male Reproductive Health and Dysfunction","first-page":"63","article-title":"Physiology of sperm maturation and fertilization","author":"Cooper","year":"2000"},{"key":"10.1016\/j.ydbio.2007.10.013_bib9","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1242\/jcs.00930","article-title":"Junctional adhesion molecules (JAMs): more molecules with dual functions?","volume":"117","author":"Ebnet","year":"2004","journal-title":"J. Cell. Sci."},{"key":"10.1016\/j.ydbio.2007.10.013_bib10","doi-asserted-by":"crossref","first-page":"707","DOI":"10.1095\/biolreprod56.3.707","article-title":"Regulation of protein tyrosine phosphorylation during bovine sperm capacitation by a cyclic adenosine 3\u20325\u2032-monophosphate-dependent pathway","volume":"56","author":"Galantino-Homer","year":"1997","journal-title":"Biol. Reprod."},{"key":"10.1016\/j.ydbio.2007.10.013_bib11","doi-asserted-by":"crossref","first-page":"320","DOI":"10.1038\/nature02877","article-title":"Spermatid differentiation requires the assembly of a cell polarity complex downstream of junctional adhesion molecule-C","volume":"431","author":"Gliki","year":"2004","journal-title":"Nature"},{"key":"10.1016\/j.ydbio.2007.10.013_bib12","series-title":"Biol. Reprod. 2007 Special Issue, Abstract #77, 40th Annual Meeting of the Society for the Study of Reproduction, July 21\u201325th, San Antonio, Texas","article-title":"Junctional adhesion molecules in mouse and human testis and spermatozoa","author":"Gye","year":"2007"},{"key":"10.1016\/j.ydbio.2007.10.013_bib13","doi-asserted-by":"crossref","first-page":"232","DOI":"10.1002\/j.1939-4640.1998.tb01993.x","article-title":"Influence of centrifugation regimes on motility, yield and cell associations of mouse spermatozoa","volume":"19","author":"Katkov","year":"1998","journal-title":"J. Androl."},{"key":"10.1016\/j.ydbio.2007.10.013_bib14","doi-asserted-by":"crossref","first-page":"174","DOI":"10.1038\/35065539","article-title":"Defining brain wiring patterns and mechanisms through gene trapping in mice","volume":"410","author":"Leighton","year":"2001","journal-title":"Nature"},{"key":"10.1016\/j.ydbio.2007.10.013_bib15","doi-asserted-by":"crossref","first-page":"857","DOI":"10.1016\/j.addr.2005.01.005","article-title":"The JAM family of proteins","volume":"57","author":"Mandell","year":"2005","journal-title":"Adv. Drug Deliv. Rev."},{"key":"10.1016\/j.ydbio.2007.10.013_bib34","doi-asserted-by":"crossref","first-page":"9291","DOI":"10.1074\/jbc.M006991200","article-title":"Association of junctional adhesion molecule with calcium\/calmodulin-dependent serine protein kinase (CASK\/LIN-2) in human epithelial caco-2 cells","volume":"276","author":"Martinez-Estrada","year":"2001","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.ydbio.2007.10.013_bib16","doi-asserted-by":"crossref","first-page":"2085","DOI":"10.1095\/biolreprod.103.017020","article-title":"Characterization of spermatogonial stem cell maturation and differentiation in neonatal mice","volume":"69","author":"McLean","year":"2003","journal-title":"Biol. Reprod."},{"key":"10.1016\/j.ydbio.2007.10.013_bib17","doi-asserted-by":"crossref","first-page":"331","DOI":"10.1006\/dbio.2002.0728","article-title":"Targeted disruption of the Akap4 gene causes defects in sperm flagellum and motility","volume":"248","author":"Miki","year":"2002","journal-title":"Dev. Biol."},{"key":"10.1016\/j.ydbio.2007.10.013_bib18","doi-asserted-by":"crossref","first-page":"2139","DOI":"10.1093\/humrep\/13.8.2139","article-title":"Effect of seminal plasma on capacitation and hyperactivation in human spermatozoa","volume":"13","author":"Mortimer","year":"1998","journal-title":"Hum. Reprod."},{"key":"10.1016\/j.ydbio.2007.10.013_bib19","doi-asserted-by":"crossref","first-page":"747","DOI":"10.1210\/er.2003-0022","article-title":"Sertoli\u2013Sertoli and Sertoli\u2013germ cell interactions and their significance in germ cell movement in the seminiferous epithelium during spermatogenesis","volume":"25","author":"Mruk","year":"2004","journal-title":"Endocr. Rev."},{"key":"10.1016\/j.ydbio.2007.10.013_bib20","doi-asserted-by":"crossref","first-page":"540","DOI":"10.1095\/biolreprod.103.026054","article-title":"Glycolysis plays a major role for Adenosine Triphosphate Supplementation in mouse sperm flagellar movement","volume":"71","author":"Mukai","year":"2004","journal-title":"Biol. Reprod."},{"key":"10.1016\/j.ydbio.2007.10.013_bib21","first-page":"341","article-title":"Junctional adhesion molecule 1 (JAM-1)","volume":"17","author":"Naik","year":"2003","journal-title":"J. Biol. Regul. Homeost. Agents"},{"key":"10.1016\/j.ydbio.2007.10.013_bib22","doi-asserted-by":"crossref","first-page":"33742","DOI":"10.1074\/jbc.M404628200","article-title":"Targeted Ablation of Plasma membrane Ca2+-ATPase (PMCA) 1 an 4 indicates a major housekeeping function for PMCA1 and a critical role in hyperactivated sperm motility and male fertility for PMCA4","volume":"279","author":"Okunade","year":"2004","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.ydbio.2007.10.013_bib23","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1038\/ni755","article-title":"JAM-1 is a ligand of the beta(2) integrin LFA-1 involved in transendothelial migration of leukocytes","volume":"3","author":"Ostermann","year":"2002","journal-title":"Nat. Immunol."},{"key":"10.1016\/j.ydbio.2007.10.013_bib24","doi-asserted-by":"crossref","first-page":"6557","DOI":"10.1128\/MCB.00729-06","article-title":"Putative \u201cStemness\u201d Gene Jam-B is not required for maintenance of stem cell state in embryonic, neural, or hematopoietic stem cells","volume":"26","author":"Sakaguchi","year":"2006","journal-title":"Mol. Cell. Biol."},{"key":"10.1016\/j.ydbio.2007.10.013_bib25","volume":"vol. 1","author":"Sambrook","year":"2001"},{"key":"10.1016\/j.ydbio.2007.10.013_bib26","doi-asserted-by":"crossref","first-page":"28220","DOI":"10.1074\/jbc.M312599200","article-title":"Plasma membrane Ca 2+-ATPase 4 is required for sperm motility and male fertility","volume":"279","author":"Schuh","year":"2004","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.ydbio.2007.10.013_bib27","doi-asserted-by":"crossref","first-page":"319","DOI":"10.1095\/biolreprod.103.026880","article-title":"The murine testicular transcriptome: characterizing gene expression in the testis during the progression of spermatogenesis","volume":"71","author":"Shima","year":"2004","journal-title":"Biol. Reprod."},{"key":"10.1016\/j.ydbio.2007.10.013_bib28","doi-asserted-by":"crossref","first-page":"240","DOI":"10.1095\/biolreprod61.1.240","article-title":"Role of tyrosine phosphorylation of flagellar proteins in hamster sperm hyperactivation","volume":"61","author":"Si","year":"1999","journal-title":"Biol. Reprod."},{"key":"10.1016\/j.ydbio.2007.10.013_bib29","doi-asserted-by":"crossref","first-page":"903","DOI":"10.1101\/gad.6.6.903","article-title":"A gene trap approach in mouse embryonic stem cells: the lacZ reporter is activated by splicing, reflects endogenous gene expression, and is mutagenic in mice","volume":"6","author":"Skarnes","year":"1992","journal-title":"Genes Dev."},{"key":"10.1016\/j.ydbio.2007.10.013_bib30","doi-asserted-by":"crossref","first-page":"686","DOI":"10.1095\/biolreprod46.4.686","article-title":"Hyperactivation enhances mouse sperm capacity by penetrating viscoelastic media","volume":"46","author":"Suarez","year":"1992","journal-title":"Biol. Reprod."},{"key":"10.1016\/j.ydbio.2007.10.013_bib31","series-title":"Andrology: Male Reproductive Health and Dysfunction","first-page":"23","article-title":"Physiology of testicular function","author":"Weinbauer","year":"2000"},{"key":"10.1016\/j.ydbio.2007.10.013_bib32","series-title":"The Epididymis from Molecules to Clinical Practice","first-page":"417","article-title":"Acquisition and development of sperm motility upon maturation in the epididymis","author":"Yeung","year":"2002"},{"key":"10.1016\/j.ydbio.2007.10.013_bib33","doi-asserted-by":"crossref","first-page":"1730","DOI":"10.1095\/biolreprod64.6.1730","article-title":"Lack of sharing of Spam1 (Ph-20) among mouse spermatids and transmission ratio distortion","volume":"64","author":"Zheng","year":"2001","journal-title":"Biol. Reprod."}],"container-title":["Developmental Biology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S001216060701456X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S001216060701456X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,15]],"date-time":"2025-09-15T04:03:06Z","timestamp":1757908986000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S001216060701456X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,1]]},"references-count":34,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2008,1]]}},"alternative-id":["S001216060701456X"],"URL":"https:\/\/doi.org\/10.1016\/j.ydbio.2007.10.013","relation":{},"ISSN":["0012-1606"],"issn-type":[{"value":"0012-1606","type":"print"}],"subject":[],"published":{"date-parts":[[2008,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"JAM-A is present in mammalian spermatozoa where it is essential for normal motility","name":"articletitle","label":"Article Title"},{"value":"Developmental Biology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ydbio.2007.10.013","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2007 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}