{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,3]],"date-time":"2026-10-03T23:20:52Z","timestamp":1791069652783,"version":"4.1.0"},"reference-count":65,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2011,10,1]],"date-time":"2011-10-01T00:00:00Z","timestamp":1317427200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2011,10,1]],"date-time":"2011-10-01T00:00:00Z","timestamp":1317427200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2013,7,17]],"date-time":"2013-07-17T00:00:00Z","timestamp":1374019200000},"content-version":"vor","delay-in-days":655,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"},{"start":{"date-parts":[[2011,10,1]],"date-time":"2011-10-01T00:00:00Z","timestamp":1317427200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2011,10,1]],"date-time":"2011-10-01T00:00:00Z","timestamp":1317427200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2011,10,1]],"date-time":"2011-10-01T00:00:00Z","timestamp":1317427200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2011,10,1]],"date-time":"2011-10-01T00:00:00Z","timestamp":1317427200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2011,10,1]],"date-time":"2011-10-01T00:00:00Z","timestamp":1317427200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100000024","name":"Canadian Institutes of Health Research","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000024","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Developmental Biology"],"published-print":{"date-parts":[[2011,10]]},"DOI":"10.1016\/j.ydbio.2011.07.037","type":"journal-article","created":{"date-parts":[[2011,8,6]],"date-time":"2011-08-06T16:21:06Z","timestamp":1312647666000},"page":"368-378","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":97,"title":["GATA5 interacts with GATA4 and GATA6 in outflow tract development"],"prefix":"10.1016","volume":"358","author":[{"given":"Brigitte","family":"Laforest","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mona","family":"Nemer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.ydbio.2011.07.037_bb0005","doi-asserted-by":"crossref","first-page":"6975","DOI":"10.1073\/pnas.0401833101","article-title":"Essential role of GATA-4 in cell survival and drug-induced cardiotoxicity","volume":"101","author":"Aries","year":"2004","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.ydbio.2011.07.037_bb0010","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1016\/j.ydbio.2007.09.023","article-title":"Myocardium at the base of the aorta and pulmonary trunk is prefigured in the outflow tract of the heart and in subdomains of the second heart field","volume":"313","author":"Bajolle","year":"2008","journal-title":"Dev. Biol."},{"key":"10.1016\/j.ydbio.2011.07.037_bb0015","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1038\/ng0197-30","article-title":"Mutations in human TBX5 [corrected] cause limb and cardiac malformation in Holt\u2013Oram syndrome","volume":"15","author":"Basson","year":"1997","journal-title":"Nat. Genet."},{"key":"10.1016\/j.ydbio.2011.07.037_bb0020","doi-asserted-by":"crossref","first-page":"888","DOI":"10.1161\/01.RES.87.10.888","article-title":"Cardiac septal and valvular dysmorphogenesis in mice heterozygous for mutations in the homeobox gene Nkx2-5","volume":"87","author":"Biben","year":"2000","journal-title":"Circ. Res."},{"key":"10.1016\/j.ydbio.2011.07.037_bb0025","doi-asserted-by":"crossref","first-page":"709","DOI":"10.1016\/S0092-8674(01)00493-7","article-title":"A murine model of Holt\u2013Oram syndrome defines roles of the T-box transcription factor Tbx5 in cardiogenesis and disease","volume":"106","author":"Bruneau","year":"2001","journal-title":"Cell"},{"key":"10.1016\/j.ydbio.2011.07.037_bb0030","doi-asserted-by":"crossref","first-page":"826","DOI":"10.1038\/nrg1710","article-title":"Building the mammalian heart from two sources of myocardial cells","volume":"6","author":"Buckingham","year":"2005","journal-title":"Nat. Rev. Genet."},{"key":"10.1016\/j.ydbio.2011.07.037_bb0035","doi-asserted-by":"crossref","first-page":"4355","DOI":"10.1128\/MCB.19.6.4355","article-title":"Cooperative interaction between GATA-4 and GATA-6 regulates myocardial gene expression","volume":"19","author":"Charron","year":"1999","journal-title":"Mol. Cell. Biol."},{"key":"10.1016\/j.ydbio.2011.07.037_bb0040","doi-asserted-by":"crossref","first-page":"839","DOI":"10.1101\/gad.875201","article-title":"Proper coronary vascular development and heart morphogenesis depend on interaction of GATA-4 with FOG cofactors","volume":"15","author":"Crispino","year":"2001","journal-title":"Genes Dev."},{"key":"10.1016\/j.ydbio.2011.07.037_bb0045","doi-asserted-by":"crossref","first-page":"3931","DOI":"10.1242\/dev.01256","article-title":"Mef2c is a direct transcriptional target of ISL1 and GATA factors in the anterior heart field during mouse embryonic development","volume":"131","author":"Dodou","year":"2004","journal-title":"Development"},{"key":"10.1016\/j.ydbio.2011.07.037_bb0050","doi-asserted-by":"crossref","first-page":"443","DOI":"10.1038\/nature01827","article-title":"GATA4 mutations cause human congenital heart defects and reveal an interaction with TBX5","volume":"424","author":"Garg","year":"2003","journal-title":"Nature"},{"key":"10.1016\/j.ydbio.2011.07.037_bb0055","doi-asserted-by":"crossref","first-page":"923","DOI":"10.1016\/S0735-1097(03)00853-2","article-title":"Patterns of recurrence of congenital heart disease: an analysis of 6,640 consecutive pregnancies evaluated by detailed fetal echocardiography","volume":"42","author":"Gill","year":"2003","journal-title":"J. Am. Coll. Cardiol."},{"key":"10.1016\/j.ydbio.2011.07.037_bb0060","doi-asserted-by":"crossref","first-page":"2565","DOI":"10.1161\/hc4601.098427","article-title":"NKX2.5 mutations in patients with tetralogy of Fallot","volume":"104","author":"Goldmuntz","year":"2001","journal-title":"Circulation"},{"key":"10.1016\/j.ydbio.2011.07.037_bb0065","first-page":"3115","article-title":"A hormone-encoding gene identifies a pathway for cardiac but not skeletal muscle gene transcription","volume":"14","author":"Grepin","year":"1994","journal-title":"Mol. Cell. Biol."},{"key":"10.1016\/j.ydbio.2011.07.037_bb0070","doi-asserted-by":"crossref","first-page":"2387","DOI":"10.1242\/dev.124.12.2387","article-title":"Enhanced cardiogenesis in embryonic stem cells overexpressing the GATA-4 transcription factor","volume":"124","author":"Grepin","year":"1997","journal-title":"Development"},{"key":"10.1016\/j.ydbio.2011.07.037_bb0075","first-page":"1986","article-title":"Murine Jagged1\/Notch signaling in the second heart field orchestrates Fgf8 expression and tissue\u2013tissue interactions during outflow tract development","volume":"119","author":"High","year":"2009","journal-title":"J. Clin. Invest."},{"key":"10.1016\/j.ydbio.2011.07.037_bb0080","doi-asserted-by":"crossref","first-page":"1890","DOI":"10.1016\/S0735-1097(02)01886-7","article-title":"The incidence of congenital heart disease","volume":"39","author":"Hoffman","year":"2002","journal-title":"J. Am. Coll. Cardiol."},{"key":"10.1016\/j.ydbio.2011.07.037_bb0085","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1016\/j.ydbio.2010.02.001","article-title":"Targeted deletion of Hand2 in cardiac neural crest-derived cells influences cardiac gene expression and outflow tract development","volume":"341","author":"Holler","year":"2010","journal-title":"Dev. Biol."},{"key":"10.1016\/j.ydbio.2011.07.037_bb0090","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1016\/j.semcdb.2006.12.004","article-title":"Model systems for the study of heart development and disease. Cardiac neural crest and conotruncal malformations","volume":"18","author":"Hutson","year":"2007","journal-title":"Semin. Cell Dev. Biol."},{"key":"10.1016\/j.ydbio.2011.07.037_bb0095","doi-asserted-by":"crossref","first-page":"662","DOI":"10.1136\/bmj.294.6573.662","article-title":"The heritability of congenital heart disease","volume":"294","author":"Insley","year":"1987","journal-title":"Br. Med. J. (Clin. Res. Ed.)"},{"key":"10.1016\/j.ydbio.2011.07.037_bb0100","doi-asserted-by":"crossref","first-page":"435","DOI":"10.1016\/S1534-5807(01)00040-5","article-title":"The arterial pole of the mouse heart forms from Fgf10-expressing cells in pharyngeal mesoderm","volume":"1","author":"Kelly","year":"2001","journal-title":"Dev. Cell"},{"key":"10.1016\/j.ydbio.2011.07.037_bb0105","doi-asserted-by":"crossref","first-page":"13933","DOI":"10.1073\/pnas.0904744106","article-title":"GATA6 mutations cause human cardiac outflow tract defects by disrupting semaphorin-plexin signaling","volume":"106","author":"Kodo","year":"2009","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.ydbio.2011.07.037_bb0110","doi-asserted-by":"crossref","first-page":"723","DOI":"10.1242\/dev.126.9.723","article-title":"The transcription factor GATA6 is essential for early extraembryonic development","volume":"126","author":"Koutsourakis","year":"1999","journal-title":"Development"},{"key":"10.1016\/j.ydbio.2011.07.037_bb0115","doi-asserted-by":"crossref","first-page":"1048","DOI":"10.1101\/gad.11.8.1048","article-title":"GATA4 transcription factor is required for ventral morphogenesis and heart tube formation","volume":"11","author":"Kuo","year":"1997","journal-title":"Genes Dev."},{"key":"10.1016\/j.ydbio.2011.07.037_bb0120","doi-asserted-by":"crossref","DOI":"10.1172\/JCI44555","article-title":"Loss of GATA5 in mice leads to bicuspid aortic valve","volume":"121","author":"Laforest","year":"2011","journal-title":"J. Clin. Invest."},{"key":"10.1016\/j.ydbio.2011.07.037_bb0125","doi-asserted-by":"crossref","first-page":"929","DOI":"10.1172\/JCI27363","article-title":"GATA-6 regulates semaphorin 3C and is required in cardiac neural crest for cardiovascular morphogenesis","volume":"116","author":"Lepore","year":"2006","journal-title":"J. Clin. Invest."},{"key":"10.1016\/j.ydbio.2011.07.037_bb0130","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1038\/ng0197-21","article-title":"Holt\u2013Oram syndrome is caused by mutations in TBX5, a member of the Brachyury (T) gene family","volume":"15","author":"Li","year":"1997","journal-title":"Nat. Genet."},{"key":"10.1016\/j.ydbio.2011.07.037_bb0135","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1242\/dev.126.1.75","article-title":"Control of early cardiac-specific transcription of Nkx2-5 by a GATA-dependent enhancer","volume":"126","author":"Lien","year":"1999","journal-title":"Development"},{"key":"10.1016\/j.ydbio.2011.07.037_bb0140","doi-asserted-by":"crossref","first-page":"9234","DOI":"10.1073\/pnas.0910430107","article-title":"Endogenous retinoic acid regulates cardiac progenitor differentiation","volume":"107","author":"Lin","year":"2010","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"issue":"10","key":"10.1016\/j.ydbio.2011.07.037_bb0145","doi-asserted-by":"crossref","first-page":"662","DOI":"10.1038\/jhg.2010.84","article-title":"A novel GATA6 mutation in patients with tetralogy of Fallot or atrial septal defect","volume":"55","author":"Lin","year":"2010","journal-title":"J. Hum. Genet."},{"key":"10.1016\/j.ydbio.2011.07.037_bb0150","doi-asserted-by":"crossref","first-page":"3493","DOI":"10.1172\/JCI42666","article-title":"Integration of a Notch-dependent mesenchymal gene program and Bmp2-driven cell invasiveness regulates murine cardiac valve formation","volume":"120","author":"Luna-Zurita","year":"2010","journal-title":"J. Clin. Invest."},{"issue":"4","key":"10.1016\/j.ydbio.2011.07.037_bb0155","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1203\/PDR.0b013e3181ed17e4","article-title":"Identification of GATA6 sequence variants in patients with congenital heart defects","volume":"68","author":"Maitra","year":"2010","journal-title":"Pediatr. Res."},{"key":"10.1016\/j.ydbio.2011.07.037_bb0160","doi-asserted-by":"crossref","first-page":"5331","DOI":"10.1242\/dev.127.24.5331","article-title":"A GATA-dependent right ventricular enhancer controls dHAND transcription in the developing heart","volume":"127","author":"McFadden","year":"2000","journal-title":"Development"},{"key":"10.1016\/j.ydbio.2011.07.037_bb0165","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1006\/dbio.2001.0409","article-title":"The outflow tract of the heart is recruited from a novel heart-forming field","volume":"238","author":"Mjaatvedt","year":"2001","journal-title":"Dev. Biol."},{"key":"10.1016\/j.ydbio.2011.07.037_bb0170","doi-asserted-by":"crossref","first-page":"38949","DOI":"10.1074\/jbc.R000029200","article-title":"The zinc finger-containing transcription factors GATA-4, -5, and -6 \u2014 ubiquitously expressed regulators of tissue-specific gene expression","volume":"275","author":"Molkentin","year":"2000","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.ydbio.2011.07.037_bb0175","doi-asserted-by":"crossref","first-page":"1061","DOI":"10.1101\/gad.11.8.1061","article-title":"Requirement of the transcription factor GATA4 for heart tube formation and ventral morphogenesis","volume":"11","author":"Molkentin","year":"1997","journal-title":"Genes Dev."},{"key":"10.1016\/j.ydbio.2011.07.037_bb0180","doi-asserted-by":"crossref","first-page":"1422","DOI":"10.1161\/CIRCRESAHA.108.180083","article-title":"Cardiac neural crest expression of Hand2 regulates outflow and second heart field development","volume":"103","author":"Morikawa","year":"2008","journal-title":"Circ. Res."},{"key":"10.1016\/j.ydbio.2011.07.037_bb0185","doi-asserted-by":"crossref","first-page":"E77","DOI":"10.1016\/S0008-6363(95)00233-2","article-title":"Inhibition of outflow cushion mesenchyme formation in retinoic acid-induced complete transposition of the great arteries","volume":"31","author":"Nakajima","year":"1996","journal-title":"Cardiovasc. Res."},{"key":"10.1016\/j.ydbio.2011.07.037_bb0190","doi-asserted-by":"crossref","first-page":"4045","DOI":"10.1242\/dev.129.17.4045","article-title":"Cooperative interaction between GATA-5 and NF-ATc regulates endothelial-endocardial differentiation of cardiogenic cells","volume":"129","author":"Nemer","year":"2002","journal-title":"Development"},{"key":"10.1016\/j.ydbio.2011.07.037_bb0195","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1016\/S0012-1606(02)00026-X","article-title":"Transcriptional activation of BMP-4 and regulation of mammalian organogenesis by GATA-4 and -6","volume":"254","author":"Nemer","year":"2003","journal-title":"Dev. Biol."},{"key":"10.1016\/j.ydbio.2011.07.037_bb0200","series-title":"Heart Development and Regeneration","article-title":"GATA Factors","author":"Nemer","year":"2010"},{"key":"10.1016\/j.ydbio.2011.07.037_bb0205","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1002\/humu.9410","article-title":"A novel mutation in the GATA4 gene in patients with tetralogy of Fallot","volume":"27","author":"Nemer","year":"2006","journal-title":"Hum. Mutat."},{"key":"10.1016\/j.ydbio.2011.07.037_bb0210","doi-asserted-by":"crossref","first-page":"416","DOI":"10.1016\/S0959-437X(02)00319-2","article-title":"The GATA family (vertebrates and invertebrates)","volume":"12","author":"Patient","year":"2002","journal-title":"Curr. Opin. Genet. Dev."},{"key":"10.1016\/j.ydbio.2011.07.037_bb0215","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1002\/(SICI)1096-8628(19990319)83:3<201::AID-AJMG11>3.0.CO;2-V","article-title":"GATA4 haploinsufficiency in patients with interstitial deletion of chromosome region 8p23.1 and congenital heart disease","volume":"83","author":"Pehlivan","year":"1999","journal-title":"Am. J. Med. Genet."},{"key":"10.1016\/j.ydbio.2011.07.037_bb0220","doi-asserted-by":"crossref","first-page":"287","DOI":"10.1016\/S0074-7696(05)43005-3","article-title":"Cell biology of cardiac cushion development","volume":"243","author":"Person","year":"2005","journal-title":"Int. Rev. Cytol."},{"key":"10.1016\/j.ydbio.2011.07.037_bb0225","doi-asserted-by":"crossref","first-page":"3015","DOI":"10.1161\/CIRCULATIONAHA.106.183056","article-title":"Genetic basis for congenital heart defects: current knowledge: a scientific statement from the American Heart Association Congenital Cardiac Defects Committee, Council on Cardiovascular Disease in the Young: endorsed by the American Academy of Pediatrics","volume":"115","author":"Pierpont","year":"2007","journal-title":"Circulation"},{"key":"10.1016\/j.ydbio.2011.07.037_bb0230","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1016\/j.ydbio.2004.08.008","article-title":"GATA4 is a dosage-sensitive regulator of cardiac morphogenesis","volume":"275","author":"Pu","year":"2004","journal-title":"Dev. Biol."},{"key":"10.1016\/j.ydbio.2011.07.037_bb0235","doi-asserted-by":"crossref","first-page":"3153","DOI":"10.1093\/hmg\/ddp254","article-title":"Partial loss of GATA factor Pannier impairs adult heart function in Drosophila","volume":"18","author":"Qian","year":"2009","journal-title":"Hum. Mol. Genet."},{"key":"10.1016\/j.ydbio.2011.07.037_bb0240","doi-asserted-by":"crossref","first-page":"677","DOI":"10.1016\/j.yjmcc.2007.06.004","article-title":"Spectrum of heart disease associated with murine and human GATA4 mutation","volume":"43","author":"Rajagopal","year":"2007","journal-title":"J. Mol. Cell. Cardiol."},{"key":"10.1016\/j.ydbio.2011.07.037_bb0245","doi-asserted-by":"crossref","first-page":"2983","DOI":"10.1101\/gad.13.22.2983","article-title":"Gata5 is required for the development of the heart and endoderm in zebrafish","volume":"13","author":"Reiter","year":"1999","journal-title":"Genes Dev."},{"key":"10.1016\/j.ydbio.2011.07.037_bb0250","doi-asserted-by":"crossref","first-page":"3607","DOI":"10.1242\/dev.02519","article-title":"Development of heart valves requires Gata4 expression in endothelial-derived cells","volume":"133","author":"Rivera-Feliciano","year":"2006","journal-title":"Development"},{"key":"10.1016\/j.ydbio.2011.07.037_bb0255","doi-asserted-by":"crossref","first-page":"5420","DOI":"10.1128\/MCB.00717-08","article-title":"GATA4 is a direct transcriptional activator of cyclin D2 and Cdk4 and is required for cardiomyocyte proliferation in anterior heart field-derived myocardium","volume":"28","author":"Rojas","year":"2008","journal-title":"Mol. Cell. Biol."},{"key":"10.1016\/j.ydbio.2011.07.037_bb0260","doi-asserted-by":"crossref","first-page":"4381","DOI":"10.1242\/dev.02607","article-title":"Developmental patterning of the cardiac atrioventricular canal by Notch and Hairy-related transcription factors","volume":"133","author":"Rutenberg","year":"2006","journal-title":"Development"},{"key":"10.1016\/j.ydbio.2011.07.037_bb0265","doi-asserted-by":"crossref","first-page":"108","DOI":"10.1126\/science.281.5373.108","article-title":"Congenital heart disease caused by mutations in the transcription factor NKX2-5","volume":"281","author":"Schott","year":"1998","journal-title":"Science"},{"key":"10.1016\/j.ydbio.2011.07.037_bb0270","doi-asserted-by":"crossref","first-page":"282","DOI":"10.1016\/j.ydbio.2008.02.037","article-title":"Twist1 function in endocardial cushion cell proliferation, migration, and differentiation during heart valve development","volume":"317","author":"Shelton","year":"2008","journal-title":"Dev. Biol."},{"key":"10.1016\/j.ydbio.2011.07.037_bb0275","doi-asserted-by":"crossref","first-page":"1765","DOI":"10.1074\/jbc.M109.038539","article-title":"Gata4 and Gata5 cooperatively regulate cardiac myocyte proliferation in mice","volume":"285","author":"Singh","year":"2010","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.ydbio.2011.07.037_bb0280","doi-asserted-by":"crossref","first-page":"154","DOI":"10.1038\/ng0697-154","article-title":"Regulation of cardiac mesodermal and neural crest development by the bhlh transcription factor, dhand","volume":"16","author":"Srivastava","year":"1997","journal-title":"Nat. Genet."},{"key":"10.1016\/j.ydbio.2011.07.037_bb0285","doi-asserted-by":"crossref","first-page":"2463","DOI":"10.1242\/dev.01827","article-title":"Tbx20 dose-dependently regulates transcription factor networks required for mouse heart and motoneuron development","volume":"132","author":"Takeuchi","year":"2005","journal-title":"Development"},{"key":"10.1016\/j.ydbio.2011.07.037_bb0290","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1101\/gad.276304","article-title":"Notch promotes epithelial-mesenchymal transition during cardiac development and oncogenic transformation","volume":"18","author":"Timmerman","year":"2004","journal-title":"Genes Dev."},{"key":"10.1016\/j.ydbio.2011.07.037_bb0295","doi-asserted-by":"crossref","first-page":"3179","DOI":"10.1242\/dev.128.16.3179","article-title":"Conotruncal myocardium arises from a secondary heart field","volume":"128","author":"Waldo","year":"2001","journal-title":"Development"},{"key":"10.1016\/j.ydbio.2011.07.037_bb0300","doi-asserted-by":"crossref","first-page":"12573","DOI":"10.1073\/pnas.0400752101","article-title":"GATA4 is essential for formation of the proepicardium and regulates cardiogenesis","volume":"101","author":"Watt","year":"2004","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.ydbio.2011.07.037_bb0305","doi-asserted-by":"crossref","first-page":"1313","DOI":"10.1161\/CIRCULATIONAHA.109.887687","article-title":"Heterogeneity of genetic modifiers ensures normal cardiac development","volume":"121","author":"Winston","year":"2010","journal-title":"Circulation"},{"key":"10.1016\/j.ydbio.2011.07.037_bb0310","doi-asserted-by":"crossref","first-page":"11189","DOI":"10.1073\/pnas.0604604103","article-title":"A threshold of GATA4 and GATA6 expression is required for cardiovascular development","volume":"103","author":"Xin","year":"2006","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.ydbio.2011.07.037_bb0315","doi-asserted-by":"crossref","first-page":"1522","DOI":"10.1172\/JCI23769","article-title":"Morphogenesis of the right ventricle requires myocardial expression of Gata4","volume":"115","author":"Zeisberg","year":"2005","journal-title":"J. Clin. Invest."},{"key":"10.1016\/j.ydbio.2011.07.037_bb0320","doi-asserted-by":"crossref","first-page":"527","DOI":"10.1016\/j.ejmg.2008.06.005","article-title":"GATA4 mutations in 486 Chinese patients with congenital heart disease","volume":"51","author":"Zhang","year":"2008","journal-title":"Eur. J. Med. Genet."},{"key":"10.1016\/j.ydbio.2011.07.037_bb0325","doi-asserted-by":"crossref","first-page":"614","DOI":"10.1016\/j.ydbio.2008.03.013","article-title":"Loss of both GATA4 and GATA6 blocks cardiac myocyte differentiation and results in acardia in mice","volume":"317","author":"Zhao","year":"2008","journal-title":"Dev. Biol."}],"container-title":["Developmental Biology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0012160611011705?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0012160611011705?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,15]],"date-time":"2025-09-15T04:25:10Z","timestamp":1757910310000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0012160611011705"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,10]]},"references-count":65,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2011,10]]}},"alternative-id":["S0012160611011705"],"URL":"https:\/\/doi.org\/10.1016\/j.ydbio.2011.07.037","relation":{},"ISSN":["0012-1606"],"issn-type":[{"value":"0012-1606","type":"print"}],"subject":[],"published":{"date-parts":[[2011,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"GATA5 interacts with GATA4 and GATA6 in outflow tract development","name":"articletitle","label":"Article Title"},{"value":"Developmental Biology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ydbio.2011.07.037","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2010 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}