{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,10]],"date-time":"2026-10-10T00:57:20Z","timestamp":1791593840692,"version":"4.3.4"},"reference-count":69,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2013,5,1]],"date-time":"2013-05-01T00:00:00Z","timestamp":1367366400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2014,5,15]],"date-time":"2014-05-15T00:00:00Z","timestamp":1400112000000},"content-version":"vor","delay-in-days":379,"URL":"https:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"funder":[{"name":"Spain Fund for Cardiovascular Research (J.A.E.)","award":["R01 HL071546"],"award-info":[{"award-number":["R01 HL071546"]}]},{"name":"Medical Scientist Training Program grant (N.S., M.G.)","award":["T32 HL007954-13 (M.G.)"],"award-info":[{"award-number":["T32 HL007954-13 (M.G.)"]}]},{"name":"Medical Scientist Training Program grant (N.S., M.G.)","award":["K99-R00 HL098366 (C.M.T)"],"award-info":[{"award-number":["K99-R00 HL098366 (C.M.T)"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Developmental Biology"],"published-print":{"date-parts":[[2013,5]]},"DOI":"10.1016\/j.ydbio.2013.03.008","type":"journal-article","created":{"date-parts":[[2013,3,16]],"date-time":"2013-03-16T08:14:53Z","timestamp":1363421693000},"page":"333-344","source":"Crossref","is-referenced-by-count":40,"title":["Murine craniofacial development requires Hdac3-mediated repression of Msx gene expression"],"prefix":"10.1016","volume":"377","author":[{"given":"Nikhil","family":"Singh","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mudit","family":"Gupta","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chinmay M.","family":"Trivedi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Manvendra K.","family":"Singh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Li","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jonathan A.","family":"Epstein","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.ydbio.2013.03.008_bib1","doi-asserted-by":"crossref","first-page":"429","DOI":"10.1038\/sj.cr.7290185","article-title":"Msx homeobox gene family and craniofacial development","volume":"13","author":"Alappat","year":"2003","journal-title":"Cell Res."},{"key":"10.1016\/j.ydbio.2013.03.008_bib2","doi-asserted-by":"crossref","first-page":"391","DOI":"10.1242\/dev.124.2.391","article-title":"Ectopic application of recombinant BMP-2 and BMP-4 can change patterning of developing chick facial primordia","volume":"124","author":"Barlow","year":"1997","journal-title":"Development"},{"key":"10.1016\/j.ydbio.2013.03.008_bib3","doi-asserted-by":"crossref","first-page":"4325","DOI":"10.1242\/dev.125.21.4325","article-title":"FGFs and BMP4 induce both Msx1-independent and Msx1-dependent signaling pathways in early tooth development","volume":"125","author":"Bei","year":"1998","journal-title":"Development"},{"key":"10.1016\/j.ydbio.2013.03.008_bib4","doi-asserted-by":"crossref","first-page":"4711","DOI":"10.1242\/dev.127.21.4711","article-title":"BMP4 rescues a non-cell-autonomous function of Msx1 in tooth development","volume":"127","author":"Bei","year":"2000","journal-title":"Development"},{"key":"10.1016\/j.ydbio.2013.03.008_bib5","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1016\/j.molcel.2008.02.030","article-title":"Deletion of histone deacetylase 3 reveals critical roles in S phase progression and DNA damage control","volume":"30","author":"Bhaskara","year":"2008","journal-title":"Mol. Cell"},{"key":"10.1016\/j.ydbio.2013.03.008_bib6","doi-asserted-by":"crossref","first-page":"935","DOI":"10.1242\/dev.121.4.935","article-title":"Rhombomeric origin and rostrocaudal reassortment of neural crest cells revealed by intravital microscopy","volume":"121","author":"Birgbauer","year":"1995","journal-title":"Development"},{"key":"10.1016\/j.ydbio.2013.03.008_bib7","doi-asserted-by":"crossref","first-page":"3071","DOI":"10.1242\/dev.128.16.3071","article-title":"PlexinA2 and semaphorin signaling during cardiac neural crest development","volume":"128","author":"Brown","year":"2001","journal-title":"Development"},{"key":"10.1016\/j.ydbio.2013.03.008_bib8","doi-asserted-by":"crossref","first-page":"5153","DOI":"10.1242\/dev.01390","article-title":"A phylogenetically conserved cis-regulatory module in the Msx2 promoter is sufficient for BMP-dependent transcription in murine and Drosophila embryos","volume":"131","author":"Brugger","year":"2004","journal-title":"Development"},{"key":"10.1016\/j.ydbio.2013.03.008_bib9","doi-asserted-by":"crossref","first-page":"3035","DOI":"10.1242\/dev.122.10.3035","article-title":"Msx1 controls inductive signaling in mammalian tooth morphogenesis","volume":"122","author":"Chen","year":"1996","journal-title":"Development"},{"key":"10.1016\/j.ydbio.2013.03.008_bib10","doi-asserted-by":"crossref","first-page":"10044","DOI":"10.1073\/pnas.160245097","article-title":"Conservation of early odontogenic signaling pathways in Aves","volume":"97","author":"Chen","year":"2000","journal-title":"Proc. Nat. Acad. Sci. U.S.A."},{"key":"10.1016\/j.ydbio.2013.03.008_bib11","doi-asserted-by":"crossref","first-page":"11451","DOI":"10.1073\/pnas.94.21.11451","article-title":"Cleft palate in mice with a targeted mutation in the gamma-aminobutyric acid-producing enzyme glutamic acid decarboxylase 67","volume":"94","author":"Condie","year":"1997","journal-title":"Proc. Nat. Acad. Sci. U.S.A."},{"key":"10.1016\/j.ydbio.2013.03.008_bib12","doi-asserted-by":"crossref","first-page":"675","DOI":"10.1016\/0092-8674(95)90039-X","article-title":"Mice lacking p21CIP1\/WAF1 undergo normal development, but are defective in G1 checkpoint control","volume":"82","author":"Deng","year":"1995","journal-title":"Cell"},{"key":"10.1016\/j.ydbio.2013.03.008_bib13","doi-asserted-by":"crossref","first-page":"298","DOI":"10.1006\/dbio.1999.9258","article-title":"Ectopic Msx2 overexpression inhibits and Msx2 antisense stimulates calvarial osteoblast differentiation","volume":"209","author":"Dodig","year":"1999","journal-title":"Dev. Biol."},{"key":"10.1016\/j.ydbio.2013.03.008_bib14","doi-asserted-by":"crossref","first-page":"118","DOI":"10.1006\/dbio.2002.0815","article-title":"Apoptosis of premigratory neural crest cells in rhombomeres 3 and 5: consequences for patterning of the Branchial Region","volume":"251","author":"Ellies","year":"2002","journal-title":"Dev. Biol."},{"key":"10.1016\/j.ydbio.2013.03.008_bib15","doi-asserted-by":"crossref","first-page":"396","DOI":"10.1016\/j.ydbio.2005.02.002","article-title":"Insertion of Cre into the Pax3 locus creates a new allele of Splotch and identifies unexpected Pax3 derivatives","volume":"280","author":"Engleka","year":"2005","journal-title":"Dev. Biol."},{"key":"10.1016\/j.ydbio.2013.03.008_bib17","doi-asserted-by":"crossref","first-page":"268","DOI":"10.1126\/science.220.4594.268","article-title":"Neural crest and the origin of vertebrates: a new head","volume":"220","author":"Gans","year":"1983","journal-title":"Science"},{"key":"10.1016\/j.ydbio.2013.03.008_bib18","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1242\/dev.119.1.233","article-title":"Even-numbered rhombomeres control the apoptotic elimination of neural crest cells from odd-numbered rhombomeres in the chick hindbrain","volume":"119","author":"Graham","year":"1993","journal-title":"Development"},{"key":"10.1016\/j.ydbio.2013.03.008_bib19","doi-asserted-by":"crossref","first-page":"684","DOI":"10.1038\/372684a0","article-title":"The signalling molecule BMP4 mediates apoptosis in the rhombencephalic neural crest","volume":"372","author":"Graham","year":"1994","journal-title":"Nature"},{"key":"10.1016\/j.ydbio.2013.03.008_bib20","doi-asserted-by":"crossref","first-page":"729","DOI":"10.1016\/j.mod.2007.06.006","article-title":"Concerted action of Msx1 and Msx2 in regulating cranial neural crest cell differentiation during frontal bone development","volume":"124","author":"Han","year":"2007","journal-title":"Mech. Dev."},{"key":"10.1016\/j.ydbio.2013.03.008_bib21","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1016\/j.ydbio.2010.08.014","article-title":"Modulation of BMP signaling by Noggin is required for the maintenance of palatal epithelial integrity during palatogenesis","volume":"347","author":"He","year":"2010","journal-title":"Dev. Biol."},{"key":"10.1016\/j.ydbio.2013.03.008_bib22","doi-asserted-by":"crossref","first-page":"511","DOI":"10.1016\/j.ydbio.2010.12.021","article-title":"Epithelial Wnt\/beta-catenin signaling regulates palatal shelf fusion through regulation of Tgfbeta3 expression","volume":"350","author":"He","year":"2011","journal-title":"Dev. Biol."},{"key":"10.1016\/j.ydbio.2013.03.008_bib23","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1002\/gene.20123","article-title":"Transgenic mice that express Cre recombinase under control of a skeletal muscle-specific promoter from mef2c","volume":"42","author":"Heidt","year":"2005","journal-title":"Genesis"},{"key":"10.1016\/j.ydbio.2013.03.008_bib25","doi-asserted-by":"crossref","first-page":"1955","DOI":"10.1073\/pnas.0709663105","article-title":"Endothelial expression of the Notch ligand Jagged1 is required for vascular smooth muscle development","volume":"105","author":"High","year":"2008","journal-title":"Proc. Nat. Acad. Sci. U.S.A."},{"key":"10.1016\/j.ydbio.2013.03.008_bib26","doi-asserted-by":"crossref","first-page":"48805","DOI":"10.1074\/jbc.M305472200","article-title":"Smad4 and beta-catenin co-activators functionally interact with lymphoid-enhancing factor to regulate graded expression of Msx2","volume":"278","author":"Hussein","year":"2003","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.ydbio.2013.03.008_bib27","doi-asserted-by":"crossref","first-page":"6131","DOI":"10.1242\/dev.00793","article-title":"Msx2 and Twist cooperatively control the development of the neural crest-derived skeletogenic mesenchyme of the murine skull vault","volume":"130","author":"Ishii","year":"2003","journal-title":"Development"},{"key":"10.1016\/j.ydbio.2013.03.008_bib28","doi-asserted-by":"crossref","first-page":"5269","DOI":"10.1242\/dev.00708","article-title":"Conditional inactivation of Tgfbr2 in cranial neural crest causes cleft palate and calvaria defects","volume":"130","author":"Ito","year":"2003","journal-title":"Development"},{"key":"10.1016\/j.ydbio.2013.03.008_bib29","doi-asserted-by":"crossref","first-page":"473","DOI":"10.1007\/BF00195823","article-title":"The human homeobox gene HOX7 maps to chromosome 4p16.1 and may be implicated in Wolf\u2013Hirschhorn syndrome","volume":"84","author":"Ivens","year":"1990","journal-title":"Hum. Genet."},{"key":"10.1016\/j.ydbio.2013.03.008_bib30","doi-asserted-by":"crossref","first-page":"443","DOI":"10.1016\/0092-8674(93)90379-5","article-title":"A mutation in the homeodomain of the human MSX2 gene in a family affected with autosomal dominant craniosynostosis","volume":"75","author":"Jabs","year":"1993","journal-title":"Cell"},{"key":"10.1016\/j.ydbio.2013.03.008_bib31","doi-asserted-by":"crossref","first-page":"422","DOI":"10.1172\/JCI44244","article-title":"Cardiac neural crest orchestrates remodeling and functional maturation of mouse semilunar valves","volume":"121","author":"Jain","year":"2011","journal-title":"J. Clin. Invest."},{"key":"10.1016\/j.ydbio.2013.03.008_bib32","doi-asserted-by":"crossref","first-page":"1607","DOI":"10.1242\/dev.127.8.1607","article-title":"Fate of the mammalian cardiac neural crest","volume":"127","author":"Jiang","year":"2000","journal-title":"Development"},{"key":"10.1016\/j.ydbio.2013.03.008_bib33","first-page":"131","article-title":"The influence of the dental papilla on the development of tooth shape in embryonic mouse tooth germs","volume":"21","author":"Kollar","year":"1969","journal-title":"J. Embryol. Exp. Morphol."},{"key":"10.1016\/j.ydbio.2013.03.008_bib34","doi-asserted-by":"crossref","first-page":"3229","DOI":"10.1242\/dev.122.10.3229","article-title":"Rhombencephalic neural crest segmentation is preserved throughout craniofacial ontogeny","volume":"122","author":"K\u00f6ntges","year":"1996","journal-title":"Development"},{"key":"10.1016\/j.ydbio.2013.03.008_bib35","doi-asserted-by":"crossref","first-page":"3003","DOI":"10.1242\/dev.01877","article-title":"Analysis of Msx1; Msx2 double mutants reveals multiple roles for Msx genes in limb development","volume":"132","author":"Lallemand","year":"2005","journal-title":"Development"},{"key":"10.1016\/j.ydbio.2013.03.008_bib36","doi-asserted-by":"crossref","first-page":"3207","DOI":"10.1242\/dev.01175","article-title":"Odd-skipped related 2 (Osr2) encodes a key intrinsic regulator of secondary palate growth and morphogenesis","volume":"131","author":"Lan","year":"2004","journal-title":"Development"},{"key":"10.1016\/j.ydbio.2013.03.008_bib37","series-title":"The Neural Crest","author":"Le Douarin","year":"1982"},{"key":"10.1016\/j.ydbio.2013.03.008_bib38","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1016\/0925-4773(94)90059-0","article-title":"Regulation of the Msx2 homeobox gene during mouse embryogenesis: a transgene with 439 bp of 5\u2032 flanking sequence is expressed exclusively in the apical ectodermal ridge of the developing limb","volume":"48","author":"Liu","year":"1994","journal-title":"Mech. Dev."},{"key":"10.1016\/j.ydbio.2013.03.008_bib39","doi-asserted-by":"crossref","first-page":"6137","DOI":"10.1073\/pnas.92.13.6137","article-title":"Premature suture closure and ectopic cranial bone in mice expressing Msx2 transgenes in the developing skull","volume":"92","author":"Liu","year":"1995","journal-title":"Proc. Nat. Acad. Sci. U.S.A."},{"issue":"Suppl","key":"10.1016\/j.ydbio.2013.03.008_bib40","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1242\/dev.103.Supplement.155","article-title":"Spatial organization of the epithelium and the role of neural crest cells in the initiation of the mammalian tooth germ","volume":"103","author":"Lumsden","year":"1988","journal-title":"Development"},{"key":"10.1016\/j.ydbio.2013.03.008_bib41","doi-asserted-by":"crossref","first-page":"4","DOI":"10.1177\/10454411970080010101","article-title":"The genetic control of early tooth development","volume":"8","author":"Maas","year":"1997","journal-title":"Crit. Rev. Oral Biol. Med."},{"key":"10.1016\/j.ydbio.2013.03.008_bib42","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1006\/dbio.1997.8576","article-title":"Msx2 is a transcriptional regulator in the BMP4-mediated programmed cell death pathway","volume":"186","author":"Marazzi","year":"1997","journal-title":"Dev. Biol."},{"key":"10.1016\/j.ydbio.2013.03.008_bib43","doi-asserted-by":"crossref","first-page":"1217","DOI":"10.1093\/hmg\/ddr553","article-title":"Identification of a Tbx1\/Tbx2\/Tbx3 genetic pathway governing pharyngeal and arterial pole morphogenesis","volume":"21","author":"Mesbah","year":"2012","journal-title":"Hum. Mol. Genet."},{"key":"10.1016\/j.ydbio.2013.03.008_bib44","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1016\/0003-9969(87)90055-0","article-title":"The induction of odontogenesis in non-dental mesenchyme combined with early murine mandibular arch epithelium","volume":"32","author":"Mina","year":"1987","journal-title":"Arch. Oral Biol."},{"key":"10.1016\/j.ydbio.2013.03.008_bib45","doi-asserted-by":"crossref","first-page":"3025","DOI":"10.1242\/dev.049528","article-title":"BMPs and FGFs target Notch signalling via jagged 2 to regulate tooth morphogenesis and cytodifferentiation","volume":"137","author":"Mitsiadis","year":"2010","journal-title":"Development"},{"key":"10.1016\/j.ydbio.2013.03.008_bib46","doi-asserted-by":"crossref","first-page":"2480","DOI":"10.1101\/gad.175950.111","article-title":"Histone deacetylase 3 is an epigenomic brake in macrophage alternative activation","volume":"25","author":"Mullican","year":"2011","journal-title":"Genes Dev."},{"key":"10.1016\/j.ydbio.2013.03.008_bib47","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1002\/1526-968X(200011\/12)28:3\/4<147::AID-GENE90>3.0.CO;2-G","article-title":"Z\/EG, a double reporter mouse line that expresses enhanced green fluorescent protein upon Cre-mediated excision","volume":"28","author":"Novak","year":"2000","journal-title":"Genesis"},{"key":"10.1016\/j.ydbio.2013.03.008_bib48","doi-asserted-by":"crossref","first-page":"749","DOI":"10.1158\/0008-5472.749.65.3","article-title":"Homeobox Msx1 interacts with p53 tumor suppressor and inhibits tumor growth by inducing apoptosis","volume":"65","author":"Park","year":"2005","journal-title":"Cancer Res."},{"key":"10.1016\/j.ydbio.2013.03.008_bib49","doi-asserted-by":"crossref","first-page":"2523","DOI":"10.1101\/gad.9.20.2523","article-title":"Null mutation of Dlx-2 results in abnormal morphogenesis of proximal first and second branchial arch derivatives and abnormal differentiation in the forebrain","volume":"9","author":"Qiu","year":"1995","journal-title":"Genes Dev."},{"key":"10.1016\/j.ydbio.2013.03.008_bib50","doi-asserted-by":"crossref","first-page":"e11492","DOI":"10.1371\/journal.pone.0011492","article-title":"Histone deacetylase 3 depletion in osteo\/chondroprogenitor cells decreases bone density and increases marrow fat","volume":"5","author":"Razidlo","year":"2010","journal-title":"PLoS One"},{"key":"10.1016\/j.ydbio.2013.03.008_bib51","doi-asserted-by":"crossref","first-page":"785","DOI":"10.1016\/j.ydbio.2007.04.023","article-title":"Cooperation between the PDGF receptors in cardiac neural crest cell migration","volume":"306","author":"Richarte","year":"2007","journal-title":"Dev. Biol."},{"key":"10.1016\/j.ydbio.2013.03.008_bib52","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1016\/j.ydbio.2010.04.007","article-title":"Inactivation of Msx1 and Msx2 in neural crest reveals an unexpected role in suppressing heterotopic bone formation in the head","volume":"343","author":"Roybal","year":"2010","journal-title":"Dev. Biol."},{"key":"10.1016\/j.ydbio.2013.03.008_bib53","doi-asserted-by":"crossref","first-page":"806","DOI":"10.1038\/nrn1221","article-title":"Cranial neural crest and the building of the vertebrate head","volume":"4","author":"Santagati","year":"2003","journal-title":"Nat. Rev. Neurosci."},{"key":"10.1016\/j.ydbio.2013.03.008_bib54","doi-asserted-by":"crossref","first-page":"348","DOI":"10.1038\/ng0494-348","article-title":"Msx1 deficient mice exhibit cleft palate and abnormalities of craniofacial and tooth development","volume":"6","author":"Satokata","year":"1994","journal-title":"Nat. Genet."},{"key":"10.1016\/j.ydbio.2013.03.008_bib55","doi-asserted-by":"crossref","first-page":"391","DOI":"10.1038\/74231","article-title":"Msx2 deficiency in mice causes pleiotropic defects in bone growth and ectodermal organ formation","volume":"24","author":"Satokata","year":"2000","journal-title":"Nat. Genet."},{"key":"10.1016\/j.ydbio.2013.03.008_bib56","doi-asserted-by":"crossref","first-page":"557","DOI":"10.1038\/nrm2428","article-title":"A gene regulatory network orchestrates neural crest formation","volume":"9","author":"Sauka-Spengler","year":"2008","journal-title":"Nat. Rev. Mol. Cell Biol."},{"key":"10.1016\/j.ydbio.2013.03.008_bib58","doi-asserted-by":"crossref","first-page":"691","DOI":"10.1242\/dev.118.3.691","article-title":"Segmental migration of the hindbrain neural crest does not arise from its segmental generation","volume":"118","author":"Sechrist","year":"1993","journal-title":"Development"},{"key":"10.1016\/j.ydbio.2013.03.008_bib59","doi-asserted-by":"crossref","first-page":"541","DOI":"10.1126\/science.1068206","article-title":"Optical projection tomography as a tool for 3D microscopy and gene expression studies","volume":"296","author":"Sharpe","year":"2002","journal-title":"Science"},{"key":"10.1016\/j.ydbio.2013.03.008_bib60","doi-asserted-by":"crossref","first-page":"1240","DOI":"10.1161\/CIRCRESAHA.111.255067","article-title":"Histone deacetylase 3 regulates smooth muscle differentiation in neural crest cells and development of the cardiac outflow tract","volume":"109","author":"Singh","year":"2011","journal-title":"Circ. Res."},{"key":"10.1016\/j.ydbio.2013.03.008_bib61","doi-asserted-by":"crossref","first-page":"22667","DOI":"10.1074\/jbc.272.36.22667","article-title":"A minimal murine Msx-1 gene promoter. Organization of its cis-regulatory motifs and their role in transcriptional activation in cells in culture and in transgenic mice","volume":"272","author":"Takahashi","year":"1997","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.ydbio.2013.03.008_bib62","doi-asserted-by":"crossref","first-page":"325","DOI":"10.1016\/j.ydbio.2004.07.041","article-title":"A balance between the anti-apoptotic activity of Slug and the apoptotic activity of msx1 is required for the proper development of the neural crest","volume":"275","author":"Tr\u00edbulo","year":"2004","journal-title":"Dev. Biol."},{"key":"10.1016\/j.ydbio.2013.03.008_bib63","doi-asserted-by":"crossref","first-page":"26484","DOI":"10.1074\/jbc.M803686200","article-title":"Transgenic overexpression of Hdac3 in the heart produces increased postnatal cardiac myocyte proliferation but does not induce hypertrophy","volume":"283","author":"Trivedi","year":"2008","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.ydbio.2013.03.008_bib64","doi-asserted-by":"crossref","first-page":"2218","DOI":"10.1172\/JCI38194","article-title":"Focal adhesion kinase is required for neural crest cell morphogenesis during mouse cardiovascular development","volume":"119","author":"Vallejo-Illarramendi","year":"2009","journal-title":"J. Clin. Invest."},{"key":"10.1016\/j.ydbio.2013.03.008_bib66","doi-asserted-by":"crossref","first-page":"444","DOI":"10.1002\/ajmg.1320460420","article-title":"Newly recognized autosomal dominant disorder with craniosynostosis","volume":"46","author":"Warman","year":"1993","journal-title":"Am. J. Med. Genet."},{"key":"10.1016\/j.ydbio.2013.03.008_bib67","doi-asserted-by":"crossref","first-page":"4062","DOI":"10.1091\/mbc.E08-02-0139","article-title":"HDAC4 promotes growth of colon cancer cells via repression of p21","volume":"19","author":"Wilson","year":"2008","journal-title":"Mol. Biol. Cell"},{"key":"10.1016\/j.ydbio.2013.03.008_bib68","doi-asserted-by":"crossref","first-page":"369","DOI":"10.1093\/hmg\/6.3.369","article-title":"Perinatal lethality and multiple craniofacial malformations in MSX2 transgenic mice","volume":"6","author":"Winograd","year":"1997","journal-title":"Hum. Mol. Genet."},{"key":"10.1016\/j.ydbio.2013.03.008_bib69","first-page":"2076","article-title":"Persistent expression of Pax3 in the neural crest causes cleft palate and defective osteogenesis in mice","volume":"118","author":"Wu","year":"2008","journal-title":"J. Clin. Invest."},{"key":"10.1016\/j.ydbio.2013.03.008_bib70","first-page":"1","article-title":"Nuclear receptor co-repressors are required for the histone-deacetylase activity of HDAC3 in vivo","volume":"3","author":"You","year":"2013","journal-title":"Nat. Struct. Mol. Biol."},{"key":"10.1016\/j.ydbio.2013.03.008_bib71","doi-asserted-by":"crossref","first-page":"4397","DOI":"10.1242\/dev.02013","article-title":"Shox2-deficient mice exhibit a rare type of incomplete clefting of the secondary palate","volume":"132","author":"Yu","year":"2005","journal-title":"Development"},{"key":"10.1016\/j.ydbio.2013.03.008_bib72","doi-asserted-by":"crossref","first-page":"4135","DOI":"10.1242\/dev.129.17.4135","article-title":"Rescue of cleft palate in Msx1-deficient mice by transgenic Bmp4 reveals a network of BMP and Shh signaling in the regulation of mammalian palatogenesis","volume":"129","author":"Zhang","year":"2002","journal-title":"Development"},{"key":"10.1016\/j.ydbio.2013.03.008_bib73","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1016\/j.ydbio.2009.09.020","article-title":"Expression and requirement of T-box transcription factors Tbx2 and Tbx3 during secondary palate development in the mouse","volume":"336","author":"Zirzow","year":"2009","journal-title":"Dev. Biol."}],"container-title":["Developmental Biology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0012160613001371?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0012160613001371?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2023,6,30]],"date-time":"2023-06-30T09:49:05Z","timestamp":1688118545000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0012160613001371"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,5]]},"references-count":69,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2013,5]]}},"alternative-id":["S0012160613001371"],"URL":"https:\/\/doi.org\/10.1016\/j.ydbio.2013.03.008","relation":{},"ISSN":["0012-1606"],"issn-type":[{"value":"0012-1606","type":"print"}],"subject":[],"published":{"date-parts":[[2013,5]]}}}