{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T18:19:57Z","timestamp":1790705997257,"version":"4.1.0"},"reference-count":76,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2013,9,1]],"date-time":"2013-09-01T00:00:00Z","timestamp":1377993600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2014,9,1]],"date-time":"2014-09-01T00:00:00Z","timestamp":1409529600000},"content-version":"vor","delay-in-days":365,"URL":"https:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"funder":[{"name":"Institutional Development Award (IDeA) from the National Institute of General Medical Sciences of the National Institutes of Health","award":["P20GM103453"],"award-info":[{"award-number":["P20GM103453"]}]},{"DOI":"10.13039\/501100004737","name":"research grants from National Institutes of Health","doi-asserted-by":"crossref","award":["DE015565"],"award-info":[{"award-number":["DE015565"]}],"id":[{"id":"10.13039\/501100004737","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100004737","name":"research grants from National Institutes of Health","doi-asserted-by":"crossref","award":["DE016845"],"award-info":[{"award-number":["DE016845"]}],"id":[{"id":"10.13039\/501100004737","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/100013735","name":"Kentucky Science & Engineering Foundation","doi-asserted-by":"crossref","award":["KSEF-148\u2013502-10\u2013258"],"award-info":[{"award-number":["KSEF-148\u2013502-10\u2013258"]}],"id":[{"id":"10.13039\/100013735","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Developmental Biology"],"published-print":{"date-parts":[[2013,9]]},"DOI":"10.1016\/j.ydbio.2013.05.029","type":"journal-article","created":{"date-parts":[[2013,6,7]],"date-time":"2013-06-07T01:24:09Z","timestamp":1370568249000},"page":"170-178","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":18,"title":["Cripto is required for mesoderm and endoderm cell allocation during mouse gastrulation"],"prefix":"10.1016","volume":"381","author":[{"given":"Jiu-Zhen","family":"Jin","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jixiang","family":"Ding","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.ydbio.2013.05.029_bib1","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1016\/S1097-2765(05)00014-6","article-title":"Essential role of p38alpha MAP kinase in placental but not embryonic cardiovascular development","volume":"6","author":"Adams","year":"2000","journal-title":"Mol. Cell"},{"key":"10.1016\/j.ydbio.2013.05.029_bib2","doi-asserted-by":"crossref","first-page":"561","DOI":"10.1016\/0092-8674(94)90522-3","article-title":"HNF-3 beta is essential for node and notochord formation in mouse development","volume":"78","author":"Ang","year":"1994","journal-title":"Cell"},{"key":"10.1016\/j.ydbio.2013.05.029_bib3","doi-asserted-by":"crossref","first-page":"501","DOI":"10.1242\/dev.014357","article-title":"Pivotal roles for eomesodermin during axis formation, epithelium-to-mesenchyme transition and endoderm specification in the mouse","volume":"135","author":"Arnold","year":"2008","journal-title":"Development"},{"key":"10.1016\/j.ydbio.2013.05.029_bib4","doi-asserted-by":"crossref","first-page":"658","DOI":"10.1038\/35001072","article-title":"The organizer factors Chordin and Noggin are required for mouse forebrain development","volume":"403","author":"Bachiller","year":"2000","journal-title":"Nature"},{"key":"10.1016\/j.ydbio.2013.05.029_bib5","doi-asserted-by":"crossref","first-page":"3151","DOI":"10.1242\/dev.01907","article-title":"The Snail genes as inducers of cell movement and survival: implications in development and cancer","volume":"132","author":"Barrallo-Gimeno","year":"2005","journal-title":"Development"},{"key":"10.1016\/j.ydbio.2013.05.029_bib6","doi-asserted-by":"crossref","first-page":"84","DOI":"10.1038\/35000034","article-title":"The transcription factor snail is a repressor of E-cadherin gene expression in epithelial tumour cells","volume":"2","author":"Batlle","year":"2000","journal-title":"Nat. Cell Biol."},{"issue":"641","key":"10.1016\/j.ydbio.2013.05.029_bib7","first-page":"643","article-title":"Cripto-analysis of embryonic codes","volume":"395","author":"Beddington","year":"1998","journal-title":"Nature"},{"key":"10.1016\/j.ydbio.2013.05.029_bib8","doi-asserted-by":"crossref","first-page":"613","DOI":"10.1242\/dev.120.3.613","article-title":"Induction of a second neural axis by the mouse node","volume":"120","author":"Beddington","year":"1994","journal-title":"Development"},{"key":"10.1016\/j.ydbio.2013.05.029_bib9","doi-asserted-by":"crossref","first-page":"277","DOI":"10.1016\/S0168-9525(98)01499-1","article-title":"Anterior patterning in mouse","volume":"14","author":"Beddington","year":"1998","journal-title":"Trends Genet."},{"key":"10.1016\/j.ydbio.2013.05.029_bib10","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1016\/S0092-8674(00)80560-7","article-title":"Axis development and early asymmetry in mammals","volume":"96","author":"Beddington","year":"1999","journal-title":"Cell"},{"key":"10.1016\/j.ydbio.2013.05.029_bib11","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1016\/j.devcel.2006.07.005","article-title":"The nodal precursor acting via activin receptors induces mesoderm by maintaining a source of its convertases and BMP4","volume":"11","author":"Ben-Haim","year":"2006","journal-title":"Dev Cell"},{"key":"10.1016\/j.ydbio.2013.05.029_bib12","doi-asserted-by":"crossref","first-page":"965","DOI":"10.1038\/35082103","article-title":"Nodal signalling in the epiblast patterns the early mouse embryo","volume":"411","author":"Brennan","year":"2001","journal-title":"Nature"},{"key":"10.1016\/j.ydbio.2013.05.029_bib13","doi-asserted-by":"crossref","first-page":"877","DOI":"10.1016\/S1534-5807(03)00363-0","article-title":"Isl1 identifies a cardiac progenitor population that proliferates prior to differentiation and contributes a majority of cells to the heart","volume":"5","author":"Cai","year":"2003","journal-title":"Dev. Cell"},{"key":"10.1016\/j.ydbio.2013.05.029_bib14","doi-asserted-by":"crossref","first-page":"76","DOI":"10.1038\/35000025","article-title":"The transcription factor snail controls epithelial-mesenchymal transitions by repressing E-cadherin expression","volume":"2","author":"Cano","year":"2000","journal-title":"Nat. Cell Biol."},{"key":"10.1016\/j.ydbio.2013.05.029_bib15","doi-asserted-by":"crossref","first-page":"8184","DOI":"10.1128\/MCB.21.23.8184-8188.2001","article-title":"The mouse snail gene encodes a key regulator of the epithelial-mesenchymal transition","volume":"21","author":"Carver","year":"2001","journal-title":"Mol. Cell Biol."},{"key":"10.1016\/j.ydbio.2013.05.029_bib16","doi-asserted-by":"crossref","first-page":"407","DOI":"10.1038\/383407a0","article-title":"Cyclopia and defective axial patterning in mice lacking Sonic hedgehog gene function","volume":"383","author":"Chiang","year":"1996","journal-title":"Nature"},{"key":"10.1016\/j.ydbio.2013.05.029_bib17","doi-asserted-by":"crossref","first-page":"5539","DOI":"10.1242\/dev.02157","article-title":"Non-cell-autonomous role for Cripto in axial midline formation during vertebrate embryogenesis","volume":"132","author":"Chu","year":"2005","journal-title":"Development"},{"key":"10.1016\/j.ydbio.2013.05.029_bib18","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1016\/j.ydbio.2010.03.009","article-title":"Functional redundancy of EGF-CFC genes in epiblast and extraembryonic patterning during early mouse embryogenesis","volume":"342","author":"Chu","year":"2010","journal-title":"Dev. Biol."},{"key":"10.1016\/j.ydbio.2013.05.029_bib19","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1016\/S1534-5807(01)00017-X","article-title":"FGF signaling regulates mesoderm cell fate specification and morphogenetic movement at the primitive streak","volume":"1","author":"Ciruna","year":"2001","journal-title":"Dev. Cell"},{"key":"10.1016\/j.ydbio.2013.05.029_bib20","doi-asserted-by":"crossref","first-page":"1289","DOI":"10.1016\/j.cub.2011.06.048","article-title":"Crosstalk between Nodal\/Activin and MAPK p38 signaling is essential for anterior-posterior axis specification","volume":"21","author":"Clements","year":"2011","journal-title":"Curr. Biol."},{"key":"10.1016\/j.ydbio.2013.05.029_bib21","doi-asserted-by":"crossref","first-page":"1919","DOI":"10.1242\/dev.120.7.1919","article-title":"A primary requirement for nodal in the formation and maintenance of the primitive streak in the mouse","volume":"120","author":"Conlon","year":"1994","journal-title":"Development"},{"key":"10.1016\/j.ydbio.2013.05.029_bib22","doi-asserted-by":"crossref","first-page":"3045","DOI":"10.1101\/gad.8.24.3045","article-title":"Murine FGFR-1 is required for early postimplantation growth and axial organization","volume":"8","author":"Deng","year":"1994","journal-title":"Genes Dev."},{"key":"10.1016\/j.ydbio.2013.05.029_bib23","doi-asserted-by":"crossref","first-page":"702","DOI":"10.1038\/27215","article-title":"Cripto is required for correct orientation of the anterior-posterior axis in the mouse embryo","volume":"395","author":"Ding","year":"1998","journal-title":"Nature"},{"key":"10.1016\/j.ydbio.2013.05.029_bib24","doi-asserted-by":"crossref","first-page":"1157","DOI":"10.1242\/dev.118.4.1157","article-title":"The murine cripto gene: expression during mesoderm induction and early heart morphogenesis","volume":"118","author":"Dono","year":"1993","journal-title":"Development"},{"key":"10.1016\/j.ydbio.2013.05.029_bib25","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1242\/dev.00906","article-title":"Investigation into a role for the primitive streak in development of the murine allantois","volume":"131","author":"Downs","year":"2004","journal-title":"Development"},{"key":"10.1016\/j.ydbio.2013.05.029_bib26","doi-asserted-by":"crossref","first-page":"1717","DOI":"10.1242\/dev.01072","article-title":"Combinatorial activities of Smad2 and Smad3 regulate mesoderm formation and patterning in the mouse embryo","volume":"131","author":"Dunn","year":"2004","journal-title":"Development"},{"key":"10.1016\/j.ydbio.2013.05.029_bib27","doi-asserted-by":"crossref","first-page":"4685","DOI":"10.1242\/dev.129.20.4685","article-title":"Distinct requirements for extra-embryonic and embryonic bone morphogenetic protein 4 in the formation of the node and primitive streak and coordination of left-right asymmetry in the mouse","volume":"129","author":"Fujiwara","year":"2002","journal-title":"Development"},{"key":"10.1016\/j.ydbio.2013.05.029_bib28","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1038\/34848","article-title":"Dickkopf-1 is a member of a new family of secreted proteins and functions in head induction","volume":"391","author":"Glinka","year":"1998","journal-title":"Nature"},{"key":"10.1016\/j.ydbio.2013.05.029_bib29","doi-asserted-by":"crossref","first-page":"5193","DOI":"10.1073\/pnas.0531290100","article-title":"Cripto forms a complex with activin and type II activin receptors and can block activin signaling","volume":"100","author":"Gray","year":"2003","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"10.1016\/j.ydbio.2013.05.029_bib30","doi-asserted-by":"crossref","first-page":"821","DOI":"10.1038\/ncb862","article-title":"One-eyed pinhead and spadetail are essential for heart and somite formation","volume":"4","author":"Griffin","year":"2002","journal-title":"Nat. Cell Biol."},{"key":"10.1016\/j.ydbio.2013.05.029_bib31","doi-asserted-by":"crossref","first-page":"E3231","DOI":"10.1073\/pnas.1204017109","article-title":"Cripto regulates skeletal muscle regeneration and modulates satellite cell determination by antagonizing myostatin","volume":"109","author":"Guardiola","year":"2012","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"10.1016\/j.ydbio.2013.05.029_bib32","doi-asserted-by":"crossref","first-page":"3597","DOI":"10.1242\/dev.129.15.3597","article-title":"Mixl1 is required for axial mesendoderm morphogenesis and patterning in the murine embryo","volume":"129","author":"Hart","year":"2002","journal-title":"Development"},{"key":"10.1016\/j.ydbio.2013.05.029_bib33","doi-asserted-by":"crossref","first-page":"544","DOI":"10.1038\/nrg843","article-title":"Patterning the vertebrate heart","volume":"3","author":"Harvey","year":"2002","journal-title":"Nat. Rev. Genet."},{"key":"10.1016\/j.ydbio.2013.05.029_bib34","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1016\/S0925-4773(02)00292-7","article-title":"Efficient gene modulation in mouse epiblast using a Sox2Cre transgenic mouse strain","volume":"2","author":"Hayashi","year":"2002","journal-title":"Gene Expr. Patterns"},{"key":"10.1016\/j.ydbio.2013.05.029_bib35","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1002\/gene.10225","article-title":"Maternal inheritance of Cre activity in a Sox2Cre deleter strain","volume":"37","author":"Hayashi","year":"2003","journal-title":"Genesis"},{"key":"10.1016\/j.ydbio.2013.05.029_bib36","doi-asserted-by":"crossref","first-page":"432","DOI":"10.1016\/S0959-437X(96)80064-5","article-title":"Bone morphogenetic proteins in development","volume":"6","author":"Hogan","year":"1996","journal-title":"Curr. Opin. Genet. Dev."},{"key":"10.1016\/j.ydbio.2013.05.029_bib37","doi-asserted-by":"crossref","first-page":"567","DOI":"10.1083\/jcb.148.3.567","article-title":"Requirement for beta-catenin in anterior-posterior axis formation in mice","volume":"148","author":"Huelsken","year":"2000","journal-title":"J. Cell Biol."},{"key":"10.1016\/j.ydbio.2013.05.029_bib38","doi-asserted-by":"crossref","first-page":"1996","DOI":"10.1126\/science.1073405","article-title":"Inhibition of excess nodal signaling during mouse gastrulation by the transcriptional corepressor DRAP1","volume":"298","author":"Iratni","year":"2002","journal-title":"Science"},{"key":"10.1016\/j.ydbio.2013.05.029_bib39","doi-asserted-by":"crossref","first-page":"2367","DOI":"10.1242\/dev.129.10.2367","article-title":"Depletion of definitive gut endoderm in Sox17-null mutant mice","volume":"129","author":"Kanai-Azuma","year":"2002","journal-title":"Development"},{"key":"10.1016\/j.ydbio.2013.05.029_bib40","doi-asserted-by":"crossref","first-page":"360","DOI":"10.1038\/nrg1837","article-title":"Mesoderm induction: from caps to chips","volume":"7","author":"Kimelman","year":"2006","journal-title":"Nat. Rev. Genet."},{"key":"10.1016\/j.ydbio.2013.05.029_bib41","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1006\/dbio.2001.0289","article-title":"Complementary functions of Otx2 and Cripto in initial patterning of mouse epiblast","volume":"235","author":"Kimura","year":"2001","journal-title":"Dev. Biol."},{"key":"10.1016\/j.ydbio.2013.05.029_bib42","doi-asserted-by":"crossref","first-page":"891","DOI":"10.1242\/dev.113.3.891","article-title":"Clonal analysis of epiblast fate during germ layer formation in the mouse embryo","volume":"113","author":"Lawson","year":"1991","journal-title":"Development"},{"key":"10.1016\/j.ydbio.2013.05.029_bib43","doi-asserted-by":"crossref","first-page":"361","DOI":"10.1038\/11932","article-title":"Requirement for Wnt3 in vertebrate axis formation","volume":"22","author":"Liu","year":"1999","journal-title":"Nat. Genet."},{"key":"10.1016\/j.ydbio.2013.05.029_bib44","doi-asserted-by":"crossref","first-page":"1831","DOI":"10.1242\/dev.128.10.1831","article-title":"Genetic dissection of nodal function in patterning the mouse embryo","volume":"128","author":"Lowe","year":"2001","journal-title":"Development"},{"key":"10.1016\/j.ydbio.2013.05.029_bib45","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1038\/35077108","article-title":"LDL-receptor-related protein 6 is a receptor for Dickkopf proteins","volume":"411","author":"Mao","year":"2001","journal-title":"Nature"},{"key":"10.1016\/j.ydbio.2013.05.029_bib46","doi-asserted-by":"crossref","first-page":"287","DOI":"10.1016\/S1097-2765(00)80331-7","article-title":"Mouse Lefty2 and zebrafish antivin are feedback inhibitors of nodal signaling during vertebrate gastrulation","volume":"4","author":"Meno","year":"1999","journal-title":"Mol. Cell"},{"key":"10.1016\/j.ydbio.2013.05.029_bib47","doi-asserted-by":"crossref","first-page":"10454","DOI":"10.1073\/pnas.180316397","article-title":"Essential role for p38alpha mitogen-activated protein kinase in placental angiogenesis","volume":"97","author":"Mudgett","year":"2000","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"10.1016\/j.ydbio.2013.05.029_bib48","author":"Nagy","year":"2003","journal-title":"Manipulating the Mouse Embryo: A Laboratory Manual"},{"key":"10.1016\/j.ydbio.2013.05.029_bib49","doi-asserted-by":"crossref","first-page":"786","DOI":"10.1038\/31693","article-title":"Smad2 role in mesoderm formation, left-right patterning and craniofacial development","volume":"393","author":"Nomura","year":"1998","journal-title":"Nature"},{"key":"10.1016\/j.ydbio.2013.05.029_bib50","doi-asserted-by":"crossref","first-page":"707","DOI":"10.1038\/17820","article-title":"The head inducer Cerberus is a multifunctional antagonist of Nodal, BMP and Wnt signals","volume":"397","author":"Piccolo","year":"1999","journal-title":"Nature"},{"key":"10.1016\/j.ydbio.2013.05.029_bib51","doi-asserted-by":"crossref","first-page":"3437","DOI":"10.1242\/dev.126.15.3437","article-title":"MesP1 is expressed in the heart precursor cells and required for the formation of a single heart tube","volume":"126","author":"Saga","year":"1999","journal-title":"Development"},{"key":"10.1016\/j.ydbio.2013.05.029_bib52","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1242\/dev.124.2.327","article-title":"The one-eyed pinhead gene functions in mesoderm and endoderm formation in zebrafish and interacts with no tail","volume":"124","author":"Schier","year":"1997","journal-title":"Development"},{"key":"10.1016\/j.ydbio.2013.05.029_bib53","doi-asserted-by":"crossref","first-page":"385","DOI":"10.1038\/35000126","article-title":"Nodal signalling in vertebrate development","volume":"403","author":"Schier","year":"2000","journal-title":"Nature"},{"key":"10.1016\/j.ydbio.2013.05.029_bib54","doi-asserted-by":"crossref","first-page":"182","DOI":"10.1016\/j.stem.2008.06.018","article-title":"Establishment of endoderm progenitors by SOX transcription factor expression in human embryonic stem cells","volume":"3","author":"Seguin","year":"2008","journal-title":"Cell Stem Cell"},{"key":"10.1016\/j.ydbio.2013.05.029_bib55","doi-asserted-by":"crossref","first-page":"951","DOI":"10.1016\/S0960-9822(01)00290-1","article-title":"Head inducer Dickkopf-1 is a ligand for Wnt coreceptor LRP6","volume":"11","author":"Semenov","year":"2001","journal-title":"Curr. Biol."},{"key":"10.1016\/j.ydbio.2013.05.029_bib56","doi-asserted-by":"crossref","first-page":"425","DOI":"10.1038\/374425a0","article-title":"Requirement for Lim1 in head-organizer function","volume":"374","author":"Shawlot","year":"1995","journal-title":"Nature"},{"key":"10.1016\/j.ydbio.2013.05.029_bib57","doi-asserted-by":"crossref","first-page":"4925","DOI":"10.1242\/dev.126.22.4925","article-title":"Lim1 is required in both primitive streak-derived tissues and visceral endoderm for head formation in the mouse","volume":"126","author":"Shawlot","year":"1999","journal-title":"Development"},{"key":"10.1016\/j.ydbio.2013.05.029_bib58","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1006\/meth.2001.1152","article-title":"Identification of differentially expressed genes in mouse development using differential display and in situ hybridization","volume":"24","author":"Shen","year":"2001","journal-title":"Methods"},{"key":"10.1016\/j.ydbio.2013.05.029_bib59","doi-asserted-by":"crossref","first-page":"1023","DOI":"10.1242\/dev.000166","article-title":"Nodal signaling: developmental roles and regulation","volume":"134","author":"Shen","year":"2007","journal-title":"Development"},{"key":"10.1016\/j.ydbio.2013.05.029_bib60","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1016\/S0168-9525(00)02006-0","article-title":"The EGF-CFC gene family in vertebrate development","volume":"16","author":"Shen","year":"2000","journal-title":"Trends Genet."},{"key":"10.1016\/j.ydbio.2013.05.029_bib61","doi-asserted-by":"crossref","first-page":"429","DOI":"10.1242\/dev.124.2.429","article-title":"A differential display strategy identifies Cryptic, a novel EGF-related gene expressed in the axial and lateral mesoderm during mouse gastrulation","volume":"124","author":"Shen","year":"1997","journal-title":"Development"},{"key":"10.1016\/j.ydbio.2013.05.029_bib62","doi-asserted-by":"crossref","first-page":"1834","DOI":"10.1101\/gad.13.14.1834","article-title":"Targeted disruption of Fgf8 causes failure of cell migration in the gastrulating mouse embryo","volume":"13","author":"Sun","year":"1999","journal-title":"Genes Dev."},{"key":"10.1016\/j.ydbio.2013.05.029_bib63","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1016\/S0925-4773(97)00123-8","article-title":"Mouse gastrulation: the formation of a mammalian body plan","volume":"68","author":"Tam","year":"1997","journal-title":"Mech Dev"},{"key":"10.1016\/j.ydbio.2013.05.029_bib64","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1242\/dev.02724","article-title":"Sequential allocation and global pattern of movement of the definitive endoderm in the mouse embryo during gastrulation","volume":"134","author":"Tam","year":"2007","journal-title":"Development"},{"key":"10.1016\/j.ydbio.2013.05.029_bib65","doi-asserted-by":"crossref","first-page":"368","DOI":"10.1038\/nrg2084","article-title":"Gene function in mouse embryogenesis: get set for gastrulation","volume":"8","author":"Tam","year":"2007","journal-title":"Nat. Rev. Genet."},{"key":"10.1016\/j.ydbio.2013.05.029_bib66","doi-asserted-by":"crossref","first-page":"703","DOI":"10.1242\/dev.115.3.703","article-title":"The somitogenetic potential of cells in the primitive streak and the tail bud of the organogenesis-stage mouse embryo","volume":"115","author":"Tam","year":"1992","journal-title":"Development"},{"key":"10.1016\/j.ydbio.2013.05.029_bib67","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1242\/dev.125.1.85","article-title":"Hex: a homeobox gene revealing peri-implantation asymmetry in the mouse embryo and an early transient marker of endothelial cell precursors","volume":"125","author":"Thomas","year":"1998","journal-title":"Development"},{"key":"10.1016\/j.ydbio.2013.05.029_bib68","doi-asserted-by":"crossref","first-page":"1033","DOI":"10.1242\/dev.124.5.1033","article-title":"nodal expression in the primitive endoderm is required for specification of the anterior axis during mouse gastrulation","volume":"124","author":"Varlet","year":"1997","journal-title":"Development"},{"key":"10.1016\/j.ydbio.2013.05.029_bib69","doi-asserted-by":"crossref","first-page":"1646","DOI":"10.1101\/gad.1100503","article-title":"Cell fate decisions within the mouse organizer are governed by graded Nodal signals","volume":"17","author":"Vincent","year":"2003","journal-title":"Genes Dev."},{"key":"10.1016\/j.ydbio.2013.05.029_bib70","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1002\/gene.10226","article-title":"Highly efficient transgene-independent recombination directed by a maternally derived SOX2CRE transgene","volume":"37","author":"Vincent","year":"2003","journal-title":"Genesis"},{"key":"10.1016\/j.ydbio.2013.05.029_bib71","doi-asserted-by":"crossref","first-page":"797","DOI":"10.1016\/S0092-8674(00)81407-5","article-title":"Smad2 signaling in extraembryonic tissues determines anterior-posterior polarity of the early mouse embryo","volume":"92","author":"Waldrip","year":"1998","journal-title":"Cell"},{"key":"10.1016\/j.ydbio.2013.05.029_bib72","doi-asserted-by":"crossref","first-page":"9378","DOI":"10.1073\/pnas.95.16.9378","article-title":"Failure of egg cylinder elongation and mesoderm induction in mouse embryos lacking the tumor suppressor smad2","volume":"95","author":"Weinstein","year":"1998","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"10.1016\/j.ydbio.2013.05.029_bib73","doi-asserted-by":"crossref","first-page":"3032","DOI":"10.1101\/gad.8.24.3032","article-title":"fgfr-1 is required for embryonic growth and mesodermal patterning during mouse gastrulation","volume":"8","author":"Yamaguchi","year":"1994","journal-title":"Genes Dev."},{"key":"10.1016\/j.ydbio.2013.05.029_bib74","doi-asserted-by":"crossref","first-page":"4439","DOI":"10.1128\/MCB.22.13.4439-4449.2002","article-title":"Dual roles of Cripto as a ligand and coreceptor in the nodal signaling pathway","volume":"22","author":"Yan","year":"2002","journal-title":"Mol. Cell Biol."},{"key":"10.1016\/j.ydbio.2013.05.029_bib75","doi-asserted-by":"crossref","first-page":"543","DOI":"10.1038\/361543a0","article-title":"Nodal is a novel TGF-beta-like gene expressed in the mouse node during gastrulation","volume":"361","author":"Zhou","year":"1993","journal-title":"Nature"},{"key":"10.1016\/j.ydbio.2013.05.029_bib76","doi-asserted-by":"crossref","first-page":"957","DOI":"10.1016\/j.cell.2006.03.048","article-title":"p38 and a p38-interacting protein are critical for downregulation of E-cadherin during mouse gastrulation","volume":"125","author":"Zohn","year":"2006","journal-title":"Cell"}],"container-title":["Developmental Biology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0012160613003114?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0012160613003114?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2022,2,24]],"date-time":"2022-02-24T04:27:56Z","timestamp":1645676876000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0012160613003114"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,9]]},"references-count":76,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2013,9]]}},"alternative-id":["S0012160613003114"],"URL":"https:\/\/doi.org\/10.1016\/j.ydbio.2013.05.029","relation":{},"ISSN":["0012-1606"],"issn-type":[{"value":"0012-1606","type":"print"}],"subject":[],"published":{"date-parts":[[2013,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Cripto is required for mesoderm and endoderm cell allocation during mouse gastrulation","name":"articletitle","label":"Article Title"},{"value":"Developmental Biology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ydbio.2013.05.029","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2013 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}