{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,3]],"date-time":"2026-10-03T22:21:26Z","timestamp":1791066086763,"version":"4.1.0"},"reference-count":63,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2013,11,1]],"date-time":"2013-11-01T00:00:00Z","timestamp":1383264000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2014,11,1]],"date-time":"2014-11-01T00:00:00Z","timestamp":1414800000000},"content-version":"vor","delay-in-days":365,"URL":"https:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"funder":[{"name":"Medical Research Council"},{"name":"Ruth Kirkstein NRSA Postdoctoral Fellowship","award":["#HD008457"],"award-info":[{"award-number":["#HD008457"]}]},{"name":"Stowers Institute"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Developmental Biology"],"published-print":{"date-parts":[[2013,11]]},"DOI":"10.1016\/j.ydbio.2013.09.016","type":"journal-article","created":{"date-parts":[[2013,9,18]],"date-time":"2013-09-18T05:30:12Z","timestamp":1379482212000},"page":"158-173","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":58,"title":["Shadow enhancers flanking the HoxB cluster direct dynamic Hox expression in early heart and endoderm development"],"prefix":"10.1016","volume":"383","author":[{"given":"Christof","family":"Nolte","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tim","family":"Jinks","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xinghao","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mar\u00eda Teresa","family":"Martinez Pastor","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robb","family":"Krumlauf","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.ydbio.2013.09.016_bib1","doi-asserted-by":"crossref","first-page":"583","DOI":"10.1242\/dev.085118","article-title":"Lrp4 and Wise interplay controls the formation and patterning of mammary and other skin appendage placodes by modulating Wnt signaling","volume":"140","author":"Ahn","year":"2013","journal-title":"Development"},{"key":"10.1016\/j.ydbio.2013.09.016_bib2","doi-asserted-by":"crossref","first-page":"431","DOI":"10.1146\/annurev.cellbio.042308.113423","article-title":"Hox genes and segmentation of the hindbrain and axial skeleton","volume":"25","author":"Alexander","year":"2009","journal-title":"Annu. Rev. Cell Dev. Biol."},{"key":"10.1016\/j.ydbio.2013.09.016_bib3","doi-asserted-by":"crossref","first-page":"4075","DOI":"10.1242\/dev.129.17.4075","article-title":"Stomach regional specification requires Hoxa5-driven mesenchymal\u2013epithelial signaling","volume":"129","author":"Aubin","year":"2002","journal-title":"Development"},{"key":"10.1016\/j.ydbio.2013.09.016_bib4","doi-asserted-by":"crossref","first-page":"266","DOI":"10.1016\/j.ydbio.2011.02.029","article-title":"Hox genes define distinct progenitor sub-domains within the second heart field","volume":"353","author":"Bertrand","year":"2011","journal-title":"Dev. Biol."},{"key":"10.1016\/j.ydbio.2013.09.016_bib5","doi-asserted-by":"crossref","first-page":"232","DOI":"10.1006\/dbio.1996.0159","article-title":"Targeted disruption ofHoxc4 causes esophageal defects and vertebral transformations","volume":"177","author":"Boulet","year":"1996","journal-title":"Dev. Biol."},{"key":"10.1016\/j.ydbio.2013.09.016_bib6","doi-asserted-by":"crossref","first-page":"826","DOI":"10.1038\/nrg1710","article-title":"Building the mammalian heart from two sources of myocardial cells","volume":"6","author":"Buckingham","year":"2005","journal-title":"Nat. Rev. Genet."},{"key":"10.1016\/j.ydbio.2013.09.016_bib7","doi-asserted-by":"crossref","first-page":"473","DOI":"10.1038\/350473a0","article-title":"Regionally restricted developmental defects resulting from targeted disruption of the mouse homeobox gene hox1.5","volume":"350","author":"Chisaka","year":"1991","journal-title":"Nature"},{"key":"10.1016\/j.ydbio.2013.09.016_bib8","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1146\/annurev.physiol.60.1.267","article-title":"Role of cardiac neural crest cells in cardiovascular development","volume":"60","author":"Creazzo","year":"1998","journal-title":"Annu. Rev. Physiol."},{"key":"10.1016\/j.ydbio.2013.09.016_bib9","doi-asserted-by":"crossref","first-page":"2931","DOI":"10.1242\/dev.01897","article-title":"Developmental regulation of the Hox genes during axial morphogenesis in the mouse","volume":"132","author":"Deschamps","year":"2005","journal-title":"Development"},{"key":"10.1016\/j.ydbio.2013.09.016_bib10","doi-asserted-by":"crossref","first-page":"e27624","DOI":"10.1371\/journal.pone.0027624","article-title":"A retinoic acid responsive Hoxa3 transgene expressed in embryonic pharyngeal endoderm, cardiac neural crest and a subdomain of the second heart field","volume":"6","author":"Diman","year":"2011","journal-title":"PLoS One"},{"key":"10.1016\/j.ydbio.2013.09.016_bib11","doi-asserted-by":"crossref","first-page":"1767","DOI":"10.1101\/gad.5.10.1767","article-title":"Hox-4 genes and the morphogenesis of mammalian genitalia","volume":"5","author":"Doll\u00e9","year":"1991","journal-title":"Genes Dev."},{"key":"10.1016\/j.ydbio.2013.09.016_bib12","doi-asserted-by":"crossref","first-page":"1497","DOI":"10.1002\/j.1460-2075.1989.tb03534.x","article-title":"The structural and functional organization of the murine HOX gene family resembles that of Drosophila homeotic genes","volume":"8","author":"Duboule","year":"1989","journal-title":"EMBO J."},{"key":"10.1016\/j.ydbio.2013.09.016_bib13","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1016\/j.semcdb.2006.12.003","article-title":"Combinatorial signaling in the heart orchestrates cardiac induction, lineage specification and chamber formation","volume":"18","author":"Dunwoodie","year":"2007","journal-title":"Semin. Cell Dev. Biol."},{"key":"10.1016\/j.ydbio.2013.09.016_bib14","doi-asserted-by":"crossref","first-page":"399","DOI":"10.1242\/dev.124.2.399","article-title":"In vivo functional analysis of the Hoxa1 3\u2032 retinoid response element (3\u2032 RARE)","volume":"124","author":"Dup\u00e9","year":"1997","journal-title":"Development"},{"key":"10.1016\/j.ydbio.2013.09.016_bib15","doi-asserted-by":"crossref","first-page":"1123","DOI":"10.1242\/dev.125.6.1123","article-title":"Hoxa1 and Hoxb1 synergize in patterning the hindbrain, cranial nerves and second pharyngeal arch","volume":"125","author":"Gavalas","year":"1998","journal-title":"Development"},{"key":"10.1016\/j.ydbio.2013.09.016_bib16","doi-asserted-by":"crossref","first-page":"367","DOI":"10.1016\/0092-8674(89)90912-4","article-title":"The murine and Drosophila homeobox gene complexes have common features of organization and expression","volume":"57","author":"Graham","year":"1989","journal-title":"Cell"},{"key":"10.1016\/j.ydbio.2013.09.016_bib17","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1387\/ijdb.041946ag","article-title":"Antero-posterior patterning of the vertebrate digestive tract: 40 years after Nicole Le Douarin's PhD thesis","volume":"49","author":"Grapin-Botton","year":"2005","journal-title":"Int. J. Dev. Biol."},{"key":"10.1016\/j.ydbio.2013.09.016_bib100","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1016\/0378-1119(89)90358-2","article-title":"Site-directed mutagenesis by overlap extension using the polymerase chain reaction","volume":"77","author":"Ho","year":"1989","journal-title":"Gene"},{"key":"10.1016\/j.ydbio.2013.09.016_bib18","doi-asserted-by":"crossref","first-page":"1314","DOI":"10.1126\/science.1160631","article-title":"Shadow enhancers as a source of evolutionary novelty","volume":"321","author":"Hong","year":"2008","journal-title":"Science"},{"key":"10.1016\/j.ydbio.2013.09.016_bib19","doi-asserted-by":"crossref","first-page":"3235","DOI":"10.1242\/dev.125.16.3235","article-title":"A conserved retinoic acid responsive element in the murine Hoxb-1 gene is required for expression in the developing gut","volume":"125","author":"Huang","year":"1998","journal-title":"Development"},{"key":"10.1016\/j.ydbio.2013.09.016_bib20","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1126\/science.1101573","article-title":"Retinoic acid signaling restricts the cardiac progenitor pool","volume":"307","author":"Keegan","year":"2005","journal-title":"Science"},{"key":"10.1016\/j.ydbio.2013.09.016_bib21","doi-asserted-by":"crossref","first-page":"7864","DOI":"10.1073\/pnas.0813108106","article-title":"Cyp26 enzymes function in endoderm to regulate pancreatic field size","volume":"106","author":"Kinkel","year":"2009","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.ydbio.2013.09.016_bib22","doi-asserted-by":"crossref","first-page":"331","DOI":"10.1126\/science.1085753","article-title":"Organizing axes in time and space; 25 years of colinear tinkering","volume":"301","author":"Kmita","year":"2003","journal-title":"Science"},{"key":"10.1016\/j.ydbio.2013.09.016_bib23","doi-asserted-by":"crossref","first-page":"2651","DOI":"10.1242\/dev.122.9.2651","article-title":"Function of posterior HoxD genes in the morphogenesis of the anal sphincter","volume":"122","author":"Kondo","year":"1996","journal-title":"Development"},{"key":"10.1016\/j.ydbio.2013.09.016_bib24","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1016\/0092-8674(94)90290-9","article-title":"Hox genes in vertebrate development","volume":"78","author":"Krumlauf","year":"1994","journal-title":"Cell"},{"key":"10.1016\/j.ydbio.2013.09.016_bib25","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1006\/geno.2000.6451","article-title":"A highly efficient Escherichia coli-based chromosome engineering system adapted for recombinogenic targeting and subcloning of BAC DNA","volume":"73","author":"Lee","year":"2001","journal-title":"Genomics"},{"key":"10.1016\/j.ydbio.2013.09.016_bib26","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1093\/hmg\/ddr434","article-title":"Cardiovascular defects in a mouse model of HOXA1 syndrome","volume":"21","author":"Makki","year":"2012","journal-title":"Hum. Mol. Genet."},{"key":"10.1016\/j.ydbio.2013.09.016_bib27","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1016\/j.ydbio.2010.04.024","article-title":"Hox genes and regional patterning of the vertebrate body plan","volume":"344","author":"Mallo","year":"2010","journal-title":"Dev. Biol."},{"key":"10.1016\/j.ydbio.2013.09.016_bib28","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1006\/dbio.1997.8827","article-title":"Hox group 3 paralogs regulate the development and migration of the thymus, thyroid and parathyroid glands","volume":"195","author":"Manley","year":"1998","journal-title":"Dev. Biol."},{"key":"10.1016\/j.ydbio.2013.09.016_bib29","doi-asserted-by":"crossref","first-page":"530","DOI":"10.1016\/j.devcel.2013.01.025","article-title":"An integrated holo-enhancer unit defines tissue and gene specificity of the Fgf8 regulatory landscape","volume":"24","author":"Marinic","year":"2013","journal-title":"Dev. Cell"},{"key":"10.1016\/j.ydbio.2013.09.016_bib30","doi-asserted-by":"crossref","first-page":"567","DOI":"10.1038\/370567a0","article-title":"A conserved retinoic acid response element required for early expression of the homeobox gene Hoxb-1","volume":"370","author":"Marshall","year":"1994","journal-title":"Nature"},{"key":"10.1016\/j.ydbio.2013.09.016_bib31","doi-asserted-by":"crossref","first-page":"3877","DOI":"10.1242\/dev.00580","article-title":"A retrospective clonal analysis of the myocardium reveals two phases of clonal growth in the developing mouse heart","volume":"130","author":"Meilhac","year":"2003","journal-title":"Development"},{"key":"10.1016\/j.ydbio.2013.09.016_bib32","doi-asserted-by":"crossref","first-page":"2801","DOI":"10.1073\/pnas.93.7.2801","article-title":"Transposon tools for recombinant DNA manipulation: characterisation of transcriptional regulators from yeast, xenopus and mouse","volume":"93","author":"Morgan","year":"1996","journal-title":"Proc. Natl. Acad. Sci."},{"key":"10.1016\/j.ydbio.2013.09.016_bib33","doi-asserted-by":"crossref","first-page":"e130","DOI":"10.1371\/journal.pcbi.0020130","article-title":"Large-scale turnover of functional transcription factor binding sites in Drosophila","volume":"2","author":"Moses","year":"2006","journal-title":"PLoS Comput. Biol."},{"key":"10.1016\/j.ydbio.2013.09.016_bib34","doi-asserted-by":"crossref","first-page":"444","DOI":"10.1038\/7788","article-title":"Embryonic retinoic acid synthesis is essential for early mouse post-implantation development","volume":"21","author":"Niederreither","year":"1999","journal-title":"Nat. Genet."},{"key":"10.1016\/j.ydbio.2013.09.016_bib35","doi-asserted-by":"crossref","first-page":"1019","DOI":"10.1242\/dev.128.7.1019","article-title":"Embryonic retinoic acid synthesis is essential for heart morphogenesis in the mouse","volume":"128","author":"Niederreither","year":"2001","journal-title":"Development"},{"key":"10.1016\/j.ydbio.2013.09.016_bib36","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1016\/B978-0-12-416027-9.00004-8","article-title":"Chromatin architectures and Hox gene collinearity","volume":"104","author":"Noordermeer","year":"2013","journal-title":"Curr. Top. Dev. Biol."},{"key":"10.1016\/j.ydbio.2013.09.016_bib37","doi-asserted-by":"crossref","first-page":"924068","DOI":"10.1155\/2011\/924068","article-title":"BAC modification through serial or simultaneous use of CRE\/Lox technology","volume":"2011","author":"Parrish","year":"2011","journal-title":"J. Biomed. Biotechnol."},{"key":"10.1016\/j.ydbio.2013.09.016_bib38","doi-asserted-by":"crossref","first-page":"1562","DOI":"10.1016\/j.cub.2010.07.043","article-title":"Shadow enhancers foster robustness of Drosophila gastrulation","volume":"20","author":"Perry","year":"2010","journal-title":"Curr. Biol."},{"key":"10.1016\/j.ydbio.2013.09.016_bib39","doi-asserted-by":"crossref","first-page":"843","DOI":"10.1242\/dev.065938","article-title":"Retinoic acid signalling during development","volume":"139","author":"Rhinn","year":"2012","journal-title":"Development"},{"key":"10.1016\/j.ydbio.2013.09.016_bib40","doi-asserted-by":"crossref","first-page":"2913","DOI":"10.1073\/pnas.0712344105","article-title":"Retinoic acid deficiency alters second heart field formation","volume":"105","author":"Ryckebusch","year":"2008","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.ydbio.2013.09.016_bib41","doi-asserted-by":"crossref","first-page":"82","DOI":"10.1002\/(SICI)1097-0177(199809)213:1<82::AID-AJA8>3.0.CO;2-U","article-title":"Analysis of Hox gene expression during early avian heart development","volume":"213","author":"Searcy","year":"1998","journal-title":"Dev. Dyn."},{"key":"10.1016\/j.ydbio.2013.09.016_bib42","doi-asserted-by":"crossref","first-page":"2611","DOI":"10.1242\/dev.01845","article-title":"Shifting boundaries of retinoic acid activity control hindbrain segmental gene expression","volume":"132","author":"Sirbu","year":"2005","journal-title":"Development"},{"key":"10.1016\/j.ydbio.2013.09.016_bib43","doi-asserted-by":"crossref","first-page":"194","DOI":"10.1016\/j.ydbio.2013.03.004","article-title":"Duplications of hox gene clusters and the emergence of vertebrates","volume":"378","author":"Soshnikova","year":"2013","journal-title":"Dev. Biol."},{"key":"10.1016\/j.ydbio.2013.09.016_bib44","doi-asserted-by":"crossref","first-page":"949","DOI":"10.1242\/dev.02263","article-title":"Retinoids signal directly to zebrafish endoderm to specify insulin-expressing beta-cells","volume":"133","author":"Stafford","year":"2006","journal-title":"Development"},{"key":"10.1016\/j.ydbio.2013.09.016_bib45","doi-asserted-by":"crossref","first-page":"704","DOI":"10.1016\/j.semcdb.2005.06.004","article-title":"Cardiac neural crest","volume":"16","author":"Stoller","year":"2005","journal-title":"Semin. Cell Dev. Biol."},{"key":"10.1016\/j.ydbio.2013.09.016_bib46","doi-asserted-by":"crossref","first-page":"1025","DOI":"10.1242\/dev.125.6.1025","article-title":"Genetic interaction between Hoxa1 and Hoxb1 reveal new roles in regulation of early hindbrain patterning","volume":"125","author":"Studer","year":"1998","journal-title":"Development"},{"key":"10.1016\/j.ydbio.2013.09.016_bib47","doi-asserted-by":"crossref","first-page":"1035","DOI":"10.1038\/ng1636","article-title":"Homozygous HOXA1 mutations disrupt human brainstem, inner ear, cardiovascular and cognitive development","volume":"37","author":"Tischfield","year":"2005","journal-title":"Nat. Genet."},{"key":"10.1016\/j.ydbio.2013.09.016_bib48","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1016\/S0070-2153(09)88004-6","article-title":"Hox genes and segmentation of the vertebrate hindbrain","volume":"88","author":"Tumpel","year":"2009","journal-title":"Curr. Top. Dev. Biol."},{"key":"10.1016\/j.ydbio.2013.09.016_bib49","series-title":"HOX Genes","first-page":"103","article-title":"Hox genes and segmentation of the vertebrate hindbrain","author":"T\u00fcmpel","year":"2009"},{"key":"10.1016\/j.ydbio.2013.09.016_bib50","doi-asserted-by":"crossref","first-page":"1680","DOI":"10.1242\/dev.073486","article-title":"Not just inductive: a crucial mechanical role for the endoderm during heart tube assembly","volume":"139","author":"Varner","year":"2012","journal-title":"Development"},{"key":"10.1016\/j.ydbio.2013.09.016_bib51","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/S0070-2153(10)90001-X","article-title":"How to make a heart: the origin and regulation of cardiac progenitor cells","volume":"90","author":"Vincent","year":"2010","journal-title":"Curr. Top. Dev. Biol."},{"key":"10.1016\/j.ydbio.2013.09.016_bib52","doi-asserted-by":"crossref","first-page":"486","DOI":"10.1016\/j.tcb.2008.07.005","article-title":"SKAP-55, SKAP-55-related and ADAP adaptors modulate integrin-mediated immune-cell adhesion","volume":"18","author":"Wang","year":"2008","journal-title":"Trends Cell Biol."},{"key":"10.1016\/j.ydbio.2013.09.016_bib53","doi-asserted-by":"crossref","first-page":"923","DOI":"10.1016\/j.devcel.2008.09.009","article-title":"Hoxb5b acts downstream of retinoic acid signaling in the forelimb field to restrict heart field potential in zebrafish","volume":"15","author":"Waxman","year":"2008","journal-title":"Dev. Cell"},{"key":"10.1016\/j.ydbio.2013.09.016_bib54","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1016\/S0070-2153(09)88009-5","article-title":"Hox genes and vertebrate axial pattern","volume":"88","author":"Wellik","year":"2009","journal-title":"Curr. Top. Dev. Biol."},{"key":"10.1016\/j.ydbio.2013.09.016_bib55","doi-asserted-by":"crossref","first-page":"2048","DOI":"10.1101\/gad.5.11.2048","article-title":"Multiple spatially specific enhancers are required to reconstruct the pattern of Hox-2.6 gene expression","volume":"5","author":"Whiting","year":"1991","journal-title":"Genes Dev."},{"key":"10.1016\/j.ydbio.2013.09.016_bib56","doi-asserted-by":"crossref","first-page":"464","DOI":"10.1038\/337464a0","article-title":"Transgenic mice overexpressing the mouse homoeobox-containing gene Hox-1.4 exhibit abnormal gut development","volume":"337","author":"Wolgemuth","year":"1989","journal-title":"Nature"},{"key":"10.1016\/j.ydbio.2013.09.016_bib57","doi-asserted-by":"crossref","first-page":"1277","DOI":"10.1101\/gad.7.7a.1277","article-title":"The regulation of myogenin gene expression during the embryonic development of the mouse","volume":"7","author":"Yee","year":"1993","journal-title":"Genes Dev."},{"key":"10.1016\/j.ydbio.2013.09.016_bib58","doi-asserted-by":"crossref","first-page":"871","DOI":"10.1242\/dev.120.4.871","article-title":"Expression of the atrial-specific myosin heavy chain AMHC1 and the establishment of anteroposterior polarity in the developing chicken heart","volume":"120","author":"Yutzey","year":"1994","journal-title":"Development"},{"key":"10.1016\/j.ydbio.2013.09.016_bib59","doi-asserted-by":"crossref","first-page":"3967","DOI":"10.1242\/dev.010991","article-title":"Hox gene function in vertebrate gut morphogenesis: the case of the caecum","volume":"134","author":"Zacchetti","year":"2007","journal-title":"Development"},{"key":"10.1016\/j.ydbio.2013.09.016_bib60","doi-asserted-by":"crossref","first-page":"761","DOI":"10.1038\/44511","article-title":"Hox genes and the making of sphincters","volume":"401","author":"Zakany","year":"1999","journal-title":"Nature"},{"key":"10.1016\/j.ydbio.2013.09.016_bib61","doi-asserted-by":"crossref","first-page":"359","DOI":"10.1016\/j.gde.2007.05.011","article-title":"The role of Hox genes during vertebrate limb development","volume":"17","author":"Zakany","year":"2007","journal-title":"Curr. Opin. Genet. Dev."},{"key":"10.1016\/j.ydbio.2013.09.016_bib62","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1016\/S0092-8674(01)00436-6","article-title":"Localized and transient transcription of Hox genes suggests a link between patterning and the segmentation clock","volume":"106","author":"Z\u00e1k\u00e1ny","year":"2001","journal-title":"Cell"}],"container-title":["Developmental Biology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0012160613004909?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0012160613004909?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2022,3,6]],"date-time":"2022-03-06T09:46:54Z","timestamp":1646560014000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0012160613004909"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,11]]},"references-count":63,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2013,11]]}},"alternative-id":["S0012160613004909"],"URL":"https:\/\/doi.org\/10.1016\/j.ydbio.2013.09.016","relation":{},"ISSN":["0012-1606"],"issn-type":[{"value":"0012-1606","type":"print"}],"subject":[],"published":{"date-parts":[[2013,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Shadow enhancers flanking the HoxB cluster direct dynamic Hox expression in early heart and endoderm development","name":"articletitle","label":"Article Title"},{"value":"Developmental Biology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ydbio.2013.09.016","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2013 Elsevier Inc.","name":"copyright","label":"Copyright"}]}}