{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,3]],"date-time":"2026-06-03T08:47:01Z","timestamp":1780476421324,"version":"3.54.1"},"reference-count":88,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2014,11,1]],"date-time":"2014-11-01T00:00:00Z","timestamp":1414800000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2015,11,15]],"date-time":"2015-11-15T00:00:00Z","timestamp":1447545600000},"content-version":"vor","delay-in-days":379,"URL":"https:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/100000002","name":"NIH","doi-asserted-by":"publisher","award":["HL094763"],"award-info":[{"award-number":["HL094763"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"name":"American Heart Association Innovative Research","award":["12IRG9130012"],"award-info":[{"award-number":["12IRG9130012"]}]},{"name":"Weizmann Institute-Thomas Jefferson University Collaboration"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Developmental Biology"],"published-print":{"date-parts":[[2014,11]]},"DOI":"10.1016\/j.ydbio.2014.09.014","type":"journal-article","created":{"date-parts":[[2014,9,19]],"date-time":"2014-09-19T16:38:35Z","timestamp":1411144715000},"page":"232-244","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":39,"title":["Mesodermal expression of integrin \u03b15\u03b21 regulates neural crest development and cardiovascular morphogenesis"],"prefix":"10.1016","volume":"395","author":[{"given":"Dong","family":"Liang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xia","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ashok","family":"Mittal","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sonam","family":"Dhiman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shuan-Yu","family":"Hou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karl","family":"Degenhardt","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sophie","family":"Astrof","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.ydbio.2014.09.014_bib1","doi-asserted-by":"crossref","first-page":"669","DOI":"10.1016\/j.ydbio.2010.05.496","article-title":"Mesodermal Tbx1 is required for patterning the proximal mandible in mice","volume":"344","author":"Aggarwal","year":"2010","journal-title":"Dev. Biol."},{"key":"10.1016\/j.ydbio.2014.09.014_bib2","doi-asserted-by":"crossref","first-page":"977","DOI":"10.1242\/dev.02264","article-title":"Inactivation of Tbx1 in the pharyngeal endoderm results in 22q11DS malformations","volume":"133","author":"Arnold","year":"2006","journal-title":"Development"},{"key":"10.1016\/j.ydbio.2014.09.014_bib3","series-title":"Extracellular Matrix in Development","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1007\/978-3-642-35935-4_5","article-title":"Interactions between neural crest-derived cells and extracellular microenvironment during cardiovascular development","author":"Astrof","year":"2013"},{"key":"10.1016\/j.ydbio.2014.09.014_bib4","doi-asserted-by":"crossref","first-page":"452","DOI":"10.1215\/S1152851705000232","article-title":"The role of pericytes in blood-vessel formation and maintenance","volume":"7","author":"Bergers","year":"2005","journal-title":"Neuro-Oncol."},{"key":"10.1016\/j.ydbio.2014.09.014_bib5","doi-asserted-by":"crossref","first-page":"498","DOI":"10.1126\/science.6606851","article-title":"Dependence of thymus development on derivatives of the neural crest","volume":"223","author":"Bockman","year":"1984","journal-title":"Science"},{"key":"10.1016\/j.ydbio.2014.09.014_bib6","doi-asserted-by":"crossref","first-page":"332","DOI":"10.1002\/aja.1001800403","article-title":"Effect of neural crest ablation on development of the heart and arch arteries in the chick","volume":"180","author":"Bockman","year":"1987","journal-title":"Am. J. Anat."},{"key":"10.1016\/j.ydbio.2014.09.014_bib7","doi-asserted-by":"crossref","first-page":"3367","DOI":"10.1242\/dev.01197","article-title":"Cardiac neural crest of the mouse embryo: axial level of origin, migratory pathway and cell autonomy of the splotch (Sp2H) mutant effect","volume":"131","author":"Chan","year":"2004","journal-title":"Development"},{"key":"10.1016\/j.ydbio.2014.09.014_bib8","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1016\/j.ydbio.2011.10.019","article-title":"Influence of mesodermal Fgf8 on the differentiation of neural crest-derived postganglionic neurons","volume":"361","author":"Chen","year":"2012","journal-title":"Dev. Biol."},{"key":"10.1016\/j.ydbio.2014.09.014_bib9","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1016\/j.mod.2012.05.005","article-title":"How insights from cardiovascular developmental biology have impacted the care of infants and children with congenital heart disease","volume":"129","author":"Chin","year":"2012","journal-title":"Mech. Dev."},{"key":"10.1016\/j.ydbio.2014.09.014_bib10","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1002\/gene.10152","article-title":"What cardiovascular defect does my prenatal mouse mutant have, and why?","volume":"35","author":"Conway","year":"2003","journal-title":"Genesis"},{"key":"10.1016\/j.ydbio.2014.09.014_bib11","doi-asserted-by":"crossref","first-page":"439","DOI":"10.1242\/dev.121.2.439","article-title":"The mouse Fgf8 gene encodes a family of polypeptides and is expressed in regions that direct outgrowth and patterning in the developing embryo","volume":"121","author":"Crossley","year":"1995","journal-title":"Development"},{"key":"10.1016\/j.ydbio.2014.09.014_bib12","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1186\/1741-7007-11-107","article-title":"Requirement for integrin-linked kinase in neural crest migration and differentiation and outflow tract morphogenesis","volume":"11","author":"Dai","year":"2013","journal-title":"BMC Biol."},{"key":"10.1016\/j.ydbio.2014.09.014_bib13","doi-asserted-by":"crossref","first-page":"760","DOI":"10.1038\/nm.3185","article-title":"Semaphorin 3d signaling defects are associated with anomalous pulmonary venous connections","volume":"19","author":"Degenhardt","year":"2013","journal-title":"Nat. Med."},{"key":"10.1016\/j.ydbio.2014.09.014_bib14","doi-asserted-by":"crossref","first-page":"2687","DOI":"10.1242\/dev.120.9.2687","article-title":"Specific roles of the alpha V beta 1, alpha V beta 3 and alpha V beta 5 integrins in avian neural crest cell adhesion and migration on vitronectin","volume":"120","author":"Delannet","year":"1994","journal-title":"Development"},{"key":"10.1016\/j.ydbio.2014.09.014_bib15","doi-asserted-by":"crossref","first-page":"1428","DOI":"10.1161\/CIRCRESAHA.110.227405","article-title":"Myocardial lineage development","volume":"107","author":"Evans","year":"2010","journal-title":"Circ. Res."},{"key":"10.1016\/j.ydbio.2014.09.014_bib16","doi-asserted-by":"crossref","first-page":"70","DOI":"10.1016\/j.ydbio.2004.01.013","article-title":"Redefining the head-trunk interface for the neural crest","volume":"269","author":"Ferguson","year":"2004","journal-title":"Dev. Biol."},{"key":"10.1016\/j.ydbio.2014.09.014_bib17","doi-asserted-by":"crossref","first-page":"1798","DOI":"10.1096\/fj.05-4134com","article-title":"Fibronectin is required for integrin alphavbeta6-mediated activation of latent TGF-beta complexes containing LTBP-1","volume":"19","author":"Fontana","year":"2005","journal-title":"FASEB J."},{"key":"10.1016\/j.ydbio.2014.09.014_bib18","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1002\/dneu.20326","article-title":"Neuropilin 2\/semaphorin 3F signaling is essential for cranial neural crest migration and trigeminal ganglion condensation","volume":"67","author":"Gammill","year":"2007","journal-title":"Dev. Neurobiol."},{"key":"10.1016\/j.ydbio.2014.09.014_bib19","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1242\/dev.02187","article-title":"Guidance of trunk neural crest migration requires neuropilin 2\/semaphorin 3F signaling","volume":"133","author":"Gammill","year":"2006","journal-title":"Development"},{"key":"10.1016\/j.ydbio.2014.09.014_bib20","doi-asserted-by":"crossref","first-page":"1543","DOI":"10.1242\/dev.047696","article-title":"Ets1 is required for proper migration and differentiation of the cardiac neural crest","volume":"137","author":"Gao","year":"2010","journal-title":"Development"},{"key":"10.1016\/j.ydbio.2014.09.014_bib21","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1242\/dev.107.1.131","article-title":"Mouse homeo-genes within a subfamily, Hox-1.4, -2.6 and -5.1, display similar anteroposterior domains of expression in the embryo, but show stage- and tissue-dependent differences in their regulation","volume":"107","author":"Gaunt","year":"1989","journal-title":"Development"},{"key":"10.1016\/j.ydbio.2014.09.014_bib22","doi-asserted-by":"crossref","first-page":"1079","DOI":"10.1242\/dev.119.4.1079","article-title":"Defects in mesoderm, neural tube and vascular development in mouse embryos lacking fibronectin","volume":"119","author":"George","year":"1993","journal-title":"Development"},{"key":"10.1016\/j.ydbio.2014.09.014_bib23","doi-asserted-by":"crossref","first-page":"4309","DOI":"10.1242\/dev.124.21.4309","article-title":"Mesodermal defects and cranial neural crest apoptosis in alpha5 integrin-null embryos","volume":"124","author":"Goh","year":"1997","journal-title":"Development"},{"key":"10.1016\/j.ydbio.2014.09.014_bib24","series-title":"Syndromes of the head and neck","author":"Gorlin","year":"1990"},{"key":"10.1016\/j.ydbio.2014.09.014_bib25","doi-asserted-by":"crossref","first-page":"787","DOI":"10.1038\/375787a0","article-title":"Expression of a Delta homologue in prospective neurons in the chick","volume":"375","author":"Henrique","year":"1995","journal-title":"Nature"},{"key":"10.1016\/j.ydbio.2014.09.014_bib26","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1038\/nrg2279","article-title":"The multifaceted role of Notch in cardiac development and disease","volume":"9","author":"High","year":"2008","journal-title":"Nat. Rev. Genet."},{"key":"10.1016\/j.ydbio.2014.09.014_bib28","doi-asserted-by":"crossref","first-page":"353","DOI":"10.1172\/JCI30070","article-title":"An essential role for Notch in neural crest during cardiovascular development and smooth muscle differentiation","volume":"117","author":"High","year":"2007","journal-title":"J. Clin. Invest."},{"key":"10.1016\/j.ydbio.2014.09.014_bib29","doi-asserted-by":"crossref","first-page":"230","DOI":"10.1016\/j.ydbio.2011.08.019","article-title":"Cranial nerve fasciculation and Schwann cell migration are impaired after loss of Npn-1","volume":"359","author":"Huettl","year":"2011","journal-title":"Dev. Biol."},{"key":"10.1016\/j.ydbio.2014.09.014_bib30","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1016\/j.semcdb.2006.12.004","article-title":"Model systems for the study of heart development and disease. Cardiac neural crest and conotruncal malformations","volume":"18","author":"Hutson","year":"2007","journal-title":"Semin. Cell Dev. Biol."},{"key":"10.1016\/j.ydbio.2014.09.014_bib31","doi-asserted-by":"crossref","first-page":"3001","DOI":"10.1242\/dev.051565","article-title":"Arterial pole progenitors interpret opposing FGF\/BMP signals to proliferate or differentiate","volume":"137","author":"Hutson","year":"2010","journal-title":"Development"},{"key":"10.1016\/j.ydbio.2014.09.014_bib32","doi-asserted-by":"crossref","first-page":"486","DOI":"10.1016\/j.ydbio.2006.02.052","article-title":"Cardiac arterial pole alignment is sensitive to FGF8 signaling in the pharynx","volume":"295","author":"Hutson","year":"2006","journal-title":"Dev. Biol."},{"key":"10.1016\/j.ydbio.2014.09.014_bib33","doi-asserted-by":"crossref","first-page":"673","DOI":"10.1016\/S0092-8674(02)00971-6","article-title":"Integrins: bidirectional, allosteric signaling machines","volume":"110","author":"Hynes","year":"2002","journal-title":"Cell"},{"key":"10.1016\/j.ydbio.2014.09.014_bib34","doi-asserted-by":"crossref","first-page":"a004903","DOI":"10.1101\/cshperspect.a004903","article-title":"Overview of the matrisome \u2013 an inventory of extracellular matrix constituents and functions","volume":"4","author":"Hynes","year":"2012","journal-title":"Cold Spring Harb. Perspect. Biol."},{"key":"10.1016\/j.ydbio.2014.09.014_bib35","doi-asserted-by":"crossref","first-page":"487","DOI":"10.1016\/S0896-6273(00)80069-0","article-title":"Reprogramming Hox expression in the vertebrate hindbrain: influence of paraxial mesoderm and rhombomere transposition","volume":"16","author":"Itasaki","year":"1996","journal-title":"Neuron"},{"key":"10.1016\/j.ydbio.2014.09.014_bib36","doi-asserted-by":"crossref","first-page":"5269","DOI":"10.1242\/dev.00708","article-title":"Conditional inactivation of Tgfbr2 in cranial neural crest causes cleft palate and calvaria defects","volume":"130","author":"Ito","year":"2003","journal-title":"Development"},{"key":"10.1016\/j.ydbio.2014.09.014_bib37","doi-asserted-by":"crossref","first-page":"1607","DOI":"10.1242\/dev.127.8.1607","article-title":"Fate of the mammalian cardiac neural crest","volume":"127","author":"Jiang","year":"2000","journal-title":"Development"},{"key":"10.1016\/j.ydbio.2014.09.014_bib38","doi-asserted-by":"crossref","first-page":"2362","DOI":"10.1101\/gad.1124803","article-title":"An essential role of Bmp4 in the atrioventricular septation of the mouse heart","volume":"17","author":"Jiao","year":"2003","journal-title":"Genes Dev."},{"key":"10.1016\/j.ydbio.2014.09.014_bib39","doi-asserted-by":"crossref","first-page":"575","DOI":"10.1016\/j.devcel.2005.01.016","article-title":"Integrinalpha5 and delta\/notch signaling have complementary spatiotemporal requirements during zebrafish somitogenesis","volume":"8","author":"Julich","year":"2005","journal-title":"Dev. Cell."},{"key":"10.1016\/j.ydbio.2014.09.014_bib40","doi-asserted-by":"crossref","first-page":"2913","DOI":"10.1242\/dev.038935","article-title":"Control of extracellular matrix assembly along tissue boundaries via Integrin and Eph\/Ephrin signaling","volume":"136","author":"Julich","year":"2009","journal-title":"Development"},{"key":"10.1016\/j.ydbio.2014.09.014_bib41","doi-asserted-by":"crossref","first-page":"3481","DOI":"10.1242\/dev.01214","article-title":"Cardiac outflow tract defects in mice lacking ALK2 in neural crest cells","volume":"131","author":"Kaartinen","year":"2004","journal-title":"Development"},{"key":"10.1016\/j.ydbio.2014.09.014_bib42","series-title":"The Atlas of Mouse Development","author":"Kaufmann","year":"1992"},{"key":"10.1016\/j.ydbio.2014.09.014_bib43","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1016\/j.diff.2012.04.005","article-title":"The neural crest in cardiac congenital anomalies","volume":"84","author":"Keyte","year":"2012","journal-title":"Differentiation"},{"key":"10.1016\/j.ydbio.2014.09.014_bib44","series-title":"Cardiac Development","author":"Kirby","year":"2007"},{"key":"10.1016\/j.ydbio.2014.09.014_bib45","doi-asserted-by":"crossref","first-page":"230","DOI":"10.1006\/dbio.2000.0106","article-title":"Tie2-Cre transgenic mice: a new model for endothelial cell-lineage analysis in vivo","volume":"230","author":"Kisanuki","year":"2001","journal-title":"Dev. Biol."},{"key":"10.1016\/j.ydbio.2014.09.014_bib46","doi-asserted-by":"crossref","first-page":"463","DOI":"10.1016\/j.ceb.2006.08.009","article-title":"The matrix reorganized: extracellular matrix remodeling and integrin signaling","volume":"18","author":"Larsen","year":"2006","journal-title":"Curr. Opin. Cell Biol."},{"key":"10.1016\/j.ydbio.2014.09.014_bib47","doi-asserted-by":"crossref","first-page":"1047","DOI":"10.1161\/01.CIR.81.3.1047","article-title":"Microcinephotography of the developing heart in neural crest-ablated chick embryos","volume":"81","author":"Leatherbury","year":"1990","journal-title":"Circulation"},{"key":"10.1016\/j.ydbio.2014.09.014_bib48","doi-asserted-by":"crossref","first-page":"8916","DOI":"10.1073\/pnas.0503741102","article-title":"Myocardin-related transcription factor B is required in cardiac neural crest for smooth muscle differentiation and cardiovascular development","volume":"102","author":"Li","year":"2005","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.ydbio.2014.09.014_bib49","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1038\/35065105","article-title":"Tbx1 haploinsufficieny in the DiGeorge syndrome region causes aortic arch defects in mice","volume":"410","author":"Lindsay","year":"2001","journal-title":"Nature"},{"key":"10.1016\/j.ydbio.2014.09.014_bib50","doi-asserted-by":"crossref","first-page":"2039","DOI":"10.1242\/dev.128.11.2039","article-title":"Regulation of left-right asymmetry by thresholds of Pitx2c activity","volume":"128","author":"Liu","year":"2001","journal-title":"Development"},{"key":"10.1016\/j.ydbio.2014.09.014_bib51","doi-asserted-by":"crossref","first-page":"1248","DOI":"10.1161\/ATVBAHA.107.141069","article-title":"Developmental basis of vascular smooth muscle diversity","volume":"27","author":"Majesky","year":"2007","journal-title":"Arterioscler. Thromb. Vasc. Biol."},{"key":"10.1016\/j.ydbio.2014.09.014_bib52","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1016\/j.ydbio.2004.08.030","article-title":"Abnormalities of caudal pharyngeal pouch development in Pbx1 knockout mice mimic loss of Hox3 paralogs","volume":"276","author":"Manley","year":"2004","journal-title":"Dev. Biol."},{"key":"10.1016\/j.ydbio.2014.09.014_bib53","doi-asserted-by":"crossref","first-page":"2611","DOI":"10.1242\/dev.107078","article-title":"Nuclear to cytoplasmic shuttling of ERK promotes differentiation of muscle stem\/progenitor cells","volume":"141","author":"Michailovici","year":"2014","journal-title":"Development"},{"key":"10.1016\/j.ydbio.2014.09.014_bib54","doi-asserted-by":"crossref","first-page":"679","DOI":"10.1242\/bio.20148078","article-title":"Endothelial cells regulate neural crest and second heart field morphogenesis","volume":"3","author":"Milgrom-Hoffman","year":"2014","journal-title":"Biology Open"},{"key":"10.1016\/j.ydbio.2014.09.014_bib55","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1016\/j.ydbio.2013.06.010","article-title":"Fibronectin and integrin alpha 5 play requisite roles in cardiac morphogenesis","volume":"381","author":"Mittal","year":"2013","journal-title":"Dev. Biol."},{"key":"10.1016\/j.ydbio.2014.09.014_bib56","doi-asserted-by":"crossref","first-page":"472","DOI":"10.1016\/j.mod.2010.08.005","article-title":"Fibronectin and integrin alpha 5 play essential roles in the development of the cardiac neural crest","volume":"127","author":"Mittal","year":"2010","journal-title":"Mech. Dev."},{"key":"10.1016\/j.ydbio.2014.09.014_bib57","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1016\/S0070-2153(08)00604-2","article-title":"Mouse models of congenital cardiovascular disease","volume":"84","author":"Moon","year":"2008","journal-title":"Curr. Top. Dev. Biol."},{"key":"10.1016\/j.ydbio.2014.09.014_bib58","doi-asserted-by":"crossref","first-page":"749","DOI":"10.1203\/01.pdr.0000218420.00525.98","article-title":"Mouse models for investigating the developmental basis of human birth defects","volume":"59","author":"Moon","year":"2006","journal-title":"Pediatr. Res."},{"key":"10.1016\/j.ydbio.2014.09.014_bib59","doi-asserted-by":"crossref","first-page":"593","DOI":"10.1002\/dvg.20335","article-title":"A global double-fluorescent Cre reporter mouse","volume":"45","author":"Muzumdar","year":"2007","journal-title":"Genesis"},{"key":"10.1016\/j.ydbio.2014.09.014_bib60","doi-asserted-by":"crossref","first-page":"575","DOI":"10.1111\/j.1469-7580.2005.00473.x","article-title":"Relations and interactions between cranial mesoderm and neural crest populations","volume":"207","author":"Noden","year":"2005","journal-title":"J. Anat."},{"key":"10.1016\/j.ydbio.2014.09.014_bib61","doi-asserted-by":"crossref","first-page":"96","DOI":"10.1038\/nature00849","article-title":"Determination of left-right patterning of the mouse embryo by artificial nodal flow","volume":"418","author":"Nonaka","year":"2002","journal-title":"Nature"},{"key":"10.1016\/j.ydbio.2014.09.014_bib62","doi-asserted-by":"crossref","first-page":"613","DOI":"10.1016\/S0955-0674(00)00140-X","article-title":"Urokinase receptor and integrin partnership: coordination of signaling for cell adhesion, migration and growth","volume":"12","author":"Ossowski","year":"2000","journal-title":"Curr. Opin. Cell Biol."},{"key":"10.1016\/j.ydbio.2014.09.014_bib63","doi-asserted-by":"crossref","first-page":"90","DOI":"10.1161\/CIRCRESAHA.112.270223","article-title":"Tbx1 genetically interacts with the transforming growth factor-beta\/bone morphogenetic protein inhibitor Smad7 during great vessel remodeling","volume":"112","author":"Papangeli","year":"2013","journal-title":"Circ. Res."},{"key":"10.1016\/j.ydbio.2014.09.014_bib64","doi-asserted-by":"crossref","first-page":"2419","DOI":"10.1242\/dev.02367","article-title":"Required, tissue-specific roles for Fgf8 in outflow tract formation and remodeling","volume":"133","author":"Park","year":"2006","journal-title":"Development"},{"key":"10.1016\/j.ydbio.2014.09.014_bib65","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1002\/dvdy.21382","article-title":"Temporal-spatial ablation of neural crest in the mouse results in cardiovascular defects","volume":"237","author":"Porras","year":"2008","journal-title":"Dev. Dyn."},{"key":"10.1016\/j.ydbio.2014.09.014_bib66","doi-asserted-by":"crossref","first-page":"583","DOI":"10.1242\/bio.20148243","article-title":"Shape and position of the node and notochord along the bilateral plane of symmetry are regulated by cell-extracellular matrix interactions","volume":"3","author":"Pulina","year":"2014","journal-title":"Biology Open"},{"key":"10.1016\/j.ydbio.2014.09.014_bib67","doi-asserted-by":"crossref","first-page":"208","DOI":"10.1016\/j.ydbio.2011.03.026","article-title":"Essential roles of fibronectin in the development of the left-right embryonic body plan","volume":"354","author":"Pulina","year":"2011","journal-title":"Dev. Biol."},{"key":"10.1016\/j.ydbio.2014.09.014_bib68","doi-asserted-by":"crossref","first-page":"408","DOI":"10.1007\/s00246-009-9611-2","article-title":"Tissue-tissue interactions during morphogenesis of the outflow tract","volume":"31","author":"Rentschler","year":"2010","journal-title":"Pediatr. Cardiol."},{"key":"10.1016\/j.ydbio.2014.09.014_bib69","doi-asserted-by":"crossref","first-page":"3065","DOI":"10.1242\/dev.002501","article-title":"Cranial neural crest cells regulate head muscle patterning and differentiation during vertebrate embryogenesis","volume":"134","author":"Rinon","year":"2007","journal-title":"Development"},{"key":"10.1016\/j.ydbio.2014.09.014_bib70","doi-asserted-by":"crossref","first-page":"e18","DOI":"10.1161\/CIR.0b013e3182009701","article-title":"Heart disease and stroke statistics--2011 update: a report from the American Heart Association","volume":"123","author":"Roger","year":"2011","journal-title":"Circulation"},{"key":"10.1016\/j.ydbio.2014.09.014_bib71","doi-asserted-by":"crossref","first-page":"345","DOI":"10.1016\/S1050-1738(01)00069-X","article-title":"Mesp1 expression is the earliest sign of cardiovascular development","volume":"10","author":"Saga","year":"2000","journal-title":"Trends Cardiovasc. Med."},{"key":"10.1016\/j.ydbio.2014.09.014_bib72","doi-asserted-by":"crossref","first-page":"3437","DOI":"10.1242\/dev.126.15.3437","article-title":"MesP1 is expressed in the heart precursor cells and required for the formation of a single heart tube","volume":"126","author":"Saga","year":"1999","journal-title":"Development"},{"key":"10.1016\/j.ydbio.2014.09.014_bib73","doi-asserted-by":"crossref","first-page":"a005066","DOI":"10.1101\/cshperspect.a005066","article-title":"Integrins and extracellular matrix in mechanotransduction","volume":"2","author":"Schwartz","year":"2010","journal-title":"Cold Spring Harb. Perspect. Biol."},{"key":"10.1016\/j.ydbio.2014.09.014_bib74","doi-asserted-by":"crossref","first-page":"704","DOI":"10.1016\/j.semcdb.2005.06.004","article-title":"Cardiac neural crest","volume":"16","author":"Stoller","year":"2005","journal-title":"Semin. Cell Dev. Biol."},{"key":"10.1016\/j.ydbio.2014.09.014_bib75","doi-asserted-by":"crossref","first-page":"545","DOI":"10.1083\/jcb.200405024","article-title":"Cranial neural crest recycle surface integrins in a substratum-dependent manner to promote rapid motility","volume":"167","author":"Strachan","year":"2004","journal-title":"J. Cell Biol."},{"issue":"Pt 24","key":"10.1016\/j.ydbio.2014.09.014_bib76","doi-asserted-by":"crossref","first-page":"4715","DOI":"10.1242\/jcs.112.24.4715","article-title":"Adhesion and migration of avian neural crest cells on fibronectin require the cooperating activities of multiple integrins of the (beta)1 and (beta)3 families","volume":"112","author":"Testaz","year":"1999","journal-title":"J. Cell Sci."},{"key":"10.1016\/j.ydbio.2014.09.014_bib77","doi-asserted-by":"crossref","first-page":"2989","DOI":"10.1242\/dev.051649","article-title":"BMP-mediated inhibition of FGF signaling promotes cardiomyocyte differentiation of anterior heart field progenitors","volume":"137","author":"Tirosh-Finkel","year":"2010","journal-title":"Development"},{"key":"10.1016\/j.ydbio.2014.09.014_bib78","doi-asserted-by":"crossref","first-page":"96","DOI":"10.1038\/35000051","article-title":"Plasticity in mouse neural crest cells reveals a new patterning role for cranial mesoderm","volume":"2","author":"Trainor","year":"2000","journal-title":"Nat. Cell Biol."},{"key":"10.1016\/j.ydbio.2014.09.014_bib79","doi-asserted-by":"crossref","first-page":"381","DOI":"10.1016\/j.ydbio.2014.05.006","article-title":"Integrin-alpha5beta1 is not required for mural cell functions during development of blood vessels but is required for lymphatic-blood vessel separation and lymphovenous valve formation","volume":"392","author":"Turner","year":"2014","journal-title":"Dev. Biol."},{"key":"10.1016\/j.ydbio.2014.09.014_bib80","doi-asserted-by":"crossref","first-page":"196","DOI":"10.1093\/cvr\/cvr116","article-title":"Pharyngeal mesoderm development during embryogenesis: implications for both heart and head myogenesis","volume":"91","author":"Tzahor","year":"2011","journal-title":"Cardiovas. Res."},{"key":"10.1016\/j.ydbio.2014.09.014_bib81","doi-asserted-by":"crossref","first-page":"2218","DOI":"10.1172\/JCI38194","article-title":"Focal adhesion kinase is required for neural crest cell morphogenesis during mouse cardiovascular development","volume":"119","author":"Vallejo-Illarramendi","year":"2009","journal-title":"J. Clin. Invest."},{"key":"10.1016\/j.ydbio.2014.09.014_bib82","doi-asserted-by":"crossref","first-page":"2439","DOI":"10.1242\/dev.049551","article-title":"Endothelial alpha5 and alphav integrins cooperate in remodeling of the vasculature during development","volume":"137","author":"van der Flier","year":"2010","journal-title":"Development"},{"key":"10.1016\/j.ydbio.2014.09.014_bib83","doi-asserted-by":"crossref","first-page":"134","DOI":"10.1016\/j.ydbio.2005.08.041","article-title":"The right ventricle, outflow tract, and ventricular septum comprise a restricted expression domain within the secondary\/anterior heart field","volume":"287","author":"Verzi","year":"2005","journal-title":"Dev. Biol."},{"key":"10.1016\/j.ydbio.2014.09.014_bib84","doi-asserted-by":"crossref","first-page":"e00806","DOI":"10.7554\/eLife.00806","article-title":"PI3K\/Akt1 signalling specifies foregut precursors by generating regionalized extra-cellular matrix","volume":"2","author":"Villegas","year":"2013","journal-title":"eLife"},{"key":"10.1016\/j.ydbio.2014.09.014_bib85","doi-asserted-by":"crossref","first-page":"530","DOI":"10.1101\/gad.317405","article-title":"Inactivation of TGF{beta} signaling in neural crest stem cells leads to multiple defects reminiscent of DiGeorge syndrome","volume":"19","author":"Wurdak","year":"2005","journal-title":"Genes. Dev."},{"key":"10.1016\/j.ydbio.2014.09.014_bib86","doi-asserted-by":"crossref","first-page":"3629","DOI":"10.1242\/dev.02543","article-title":"Connexin 43-mediated modulation of polarized cell movement and the directional migration of cardiac neural crest cells","volume":"133","author":"Xu","year":"2006","journal-title":"Development"},{"key":"10.1016\/j.ydbio.2014.09.014_bib87","doi-asserted-by":"crossref","first-page":"264","DOI":"10.1006\/dbio.1999.9451","article-title":"Overlapping and independent functions of fibronectin receptor integrins in early mesodermal development","volume":"215","author":"Yang","year":"1999","journal-title":"Dev. Biol."},{"key":"10.1016\/j.ydbio.2014.09.014_bib88","doi-asserted-by":"crossref","first-page":"1093","DOI":"10.1242\/dev.119.4.1093","article-title":"Embryonic mesodermal defects in alpha 5 integrin-deficient mice","volume":"119","author":"Yang","year":"1993","journal-title":"Development"},{"key":"10.1016\/j.ydbio.2014.09.014_bib89","doi-asserted-by":"crossref","first-page":"3587","DOI":"10.1242\/dev.02539","article-title":"Mesodermal expression of Tbx1 is necessary and sufficient for pharyngeal arch and cardiac outflow tract development","volume":"133","author":"Zhang","year":"2006","journal-title":"Development"}],"container-title":["Developmental Biology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0012160614004710?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0012160614004710?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2022,4,17]],"date-time":"2022-04-17T12:34:18Z","timestamp":1650198858000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0012160614004710"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,11]]},"references-count":88,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2014,11]]}},"alternative-id":["S0012160614004710"],"URL":"https:\/\/doi.org\/10.1016\/j.ydbio.2014.09.014","relation":{},"ISSN":["0012-1606"],"issn-type":[{"value":"0012-1606","type":"print"}],"subject":[],"published":{"date-parts":[[2014,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Mesodermal expression of integrin \u03b15\u03b21 regulates neural crest development and cardiovascular morphogenesis","name":"articletitle","label":"Article Title"},{"value":"Developmental Biology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ydbio.2014.09.014","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2014 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}