{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,25]],"date-time":"2025-07-25T10:03:27Z","timestamp":1753437807913},"reference-count":72,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2016,1,1]],"date-time":"2016-01-01T00:00:00Z","timestamp":1451606400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2017,1,15]],"date-time":"2017-01-15T00:00:00Z","timestamp":1484438400000},"content-version":"vor","delay-in-days":380,"URL":"https:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"funder":[{"name":"Foundation Sante"},{"DOI":"10.13039\/100004410","name":"European Molecular Biology Organization","doi-asserted-by":"publisher","award":["ASTF 185-2009"],"award-info":[{"award-number":["ASTF 185-2009"]}],"id":[{"id":"10.13039\/100004410","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Lifelong Learning Program (LLP)-Leonardo Da Vinci-Leonardo Da Vinci Programme"},{"name":"Development Traveling Fellowships"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Developmental Biology"],"published-print":{"date-parts":[[2016,1]]},"DOI":"10.1016\/j.ydbio.2015.11.023","type":"journal-article","created":{"date-parts":[[2015,12,4]],"date-time":"2015-12-04T19:24:37Z","timestamp":1449257077000},"page":"392-405","update-policy":"http:\/\/dx.doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":8,"title":["Inactivation of Geminin in neural crest cells affects the generation and maintenance of enteric progenitor cells, leading to enteric aganglionosis"],"prefix":"10.1016","volume":"409","author":[{"given":"Athanasia","family":"Stathopoulou","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dipa","family":"Natarajan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pinelopi","family":"Nikolopoulou","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alexandra L.","family":"Patmanidi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zoi","family":"Lygerou","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vassilis","family":"Pachnis","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stavros","family":"Taraviras","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.ydbio.2015.11.023_bib1","doi-asserted-by":"crossref","first-page":"1681","DOI":"10.1242\/dev.017418","article-title":"Critical numbers of neural crest cells are required in the pathways from the neural tube to the foregut to ensure complete enteric nervous system formation","volume":"135","author":"Barlow","year":"2008","journal-title":"Development"},{"key":"10.1016\/j.ydbio.2015.11.023_bib2","doi-asserted-by":"crossref","first-page":"1782","DOI":"10.1093\/hmg\/ddr611","article-title":"Balancing neural crest cell intrinsic processes with those of the microenvironment in Tcof1 haploinsufficient mice enables complete enteric nervous system formation","volume":"21","author":"Barlow","year":"2012","journal-title":"Hum. Mol. Genet."},{"key":"10.1016\/j.ydbio.2015.11.023_bib3","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1242\/dev.122.1.309","article-title":"Distinct subpopulations of enteric neuronal progenitors defined by time of development, sympathoadrenal lineage markers and Mash-1-dependence","volume":"122","author":"Blaugrund","year":"1996","journal-title":"Development"},{"key":"10.1016\/j.ydbio.2015.11.023_bib4","doi-asserted-by":"crossref","first-page":"6387","DOI":"10.1242\/dev.00857","article-title":"Neuron and glia generating progenitors of the mammalian enteric nervous system isolated from foetal and postnatal gut cultures","volume":"130","author":"Bondurand","year":"2003","journal-title":"Development"},{"key":"10.1016\/j.ydbio.2015.11.023_bib5","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1038\/nature04733","article-title":"Polycomb complexes repress developmental regulators in murine embryonic stem cells","volume":"441","author":"Boyer","year":"2006","journal-title":"Nature"},{"key":"10.1016\/j.ydbio.2015.11.023_bib6","doi-asserted-by":"crossref","first-page":"4335","DOI":"10.1242\/dev.125.21.4335","article-title":"The sacral neural crest contributes neurons and glia to the post-umbilical gut: spatiotemporal analysis of the development of the enteric nervous system","volume":"125","author":"Burns","year":"1998","journal-title":"Development"},{"key":"10.1016\/j.ydbio.2015.11.023_bib7","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1006\/dbio.1999.9592","article-title":"Sacral neural crest cells colonise aganglionic hindgut in vivo but fail to compensate for lack of enteric ganglia","volume":"219","author":"Burns","year":"2000","journal-title":"Dev. Biol."},{"key":"10.1016\/j.ydbio.2015.11.023_bib8","doi-asserted-by":"crossref","first-page":"383","DOI":"10.1016\/S1534-5807(02)00221-6","article-title":"Association between the cell cycle and neural crest delamination through specific regulation of G1\/S transition","volume":"3","author":"Burstyn-Cohen","year":"2002","journal-title":"Dev. Cell"},{"key":"10.1016\/j.ydbio.2015.11.023_bib9","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1016\/S0896-6273(00)80514-0","article-title":"GFRalpha1 is an essential receptor component for GDNF in the developing nervous system and kidney","volume":"21","author":"Cacalano","year":"1998","journal-title":"Neuron"},{"key":"10.1016\/j.ydbio.2015.11.023_bib10","doi-asserted-by":"crossref","first-page":"1477","DOI":"10.1002\/stem.1410","article-title":"Geminin restrains mesendodermal fate acquisition of embryonic stem cells and is associated with antagonism of Wnt signaling and enhanced polycomb-mediated repression","volume":"31","author":"Caronna","year":"2013","journal-title":"Stem Cells"},{"key":"10.1016\/j.ydbio.2015.11.023_bib11","doi-asserted-by":"crossref","first-page":"1323","DOI":"10.1016\/S0960-9822(07)00562-3","article-title":"Modification of gene activity in mouse embryos in utero by a tamoxifen-inducible form of Cre recombinase","volume":"8","author":"Danielian","year":"1998","journal-title":"Curr. Biol."},{"key":"10.1016\/j.ydbio.2015.11.023_bib12","doi-asserted-by":"crossref","first-page":"4127","DOI":"10.1242\/dev.128.21.4127","article-title":"The winged-helix transcription factor Foxd3 suppresses interneuron differentiation and promotes neural crest cell fate","volume":"128","author":"Dottori","year":"2001","journal-title":"Development"},{"key":"10.1016\/j.ydbio.2015.11.023_bib13","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1242\/dev.122.1.349","article-title":"Common origin and developmental dependence on c-ret of subsets of enteric and sympathetic neuroblasts","volume":"122","author":"Durbec","year":"1996","journal-title":"Development"},{"key":"10.1016\/j.ydbio.2015.11.023_bib14","doi-asserted-by":"crossref","first-page":"2395","DOI":"10.1089\/scd.2011.0483","article-title":"Geminin is required for epithelial to mesenchymal transition at gastrulation","volume":"21","author":"Emmett","year":"2012","journal-title":"Stem Cells Dev."},{"key":"10.1016\/j.ydbio.2015.11.023_bib15","doi-asserted-by":"crossref","first-page":"236","DOI":"10.1016\/j.stem.2009.01.017","article-title":"Stage-specific control of neural crest stem cell proliferation by the small rho GTPases Cdc42 and Rac1","volume":"4","author":"Fuchs","year":"2009","journal-title":"Cell Stem Cell"},{"key":"10.1016\/j.ydbio.2015.11.023_bib16","doi-asserted-by":"crossref","first-page":"2187","DOI":"10.1242\/dev.00433","article-title":"GDNF availability determines enteric neuron number by controlling precursor proliferation","volume":"130","author":"Gianino","year":"2003","journal-title":"Development"},{"key":"10.1016\/j.ydbio.2015.11.023_bib17","doi-asserted-by":"crossref","first-page":"466","DOI":"10.1038\/nrn2137","article-title":"Enteric nervous system development and Hirschsprung's disease: advances in genetic and stem cell studies","volume":"8","author":"Heanue","year":"2007","journal-title":"Nat. Rev. Neurosci."},{"key":"10.1016\/j.ydbio.2015.11.023_bib18","doi-asserted-by":"crossref","first-page":"694","DOI":"10.1016\/j.semcdb.2005.06.005","article-title":"Sox proteins and neural crest development","volume":"16","author":"Hong","year":"2005","journal-title":"Semin. Cell Dev. Biol."},{"key":"10.1016\/j.ydbio.2015.11.023_bib19","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1615\/CritRevImmunol.v31.i3.30","article-title":"T cell proliferation and homeostasis: an emerging role for the cell cycle inhibitor geminin","volume":"31","author":"Karamitros","year":"2011","journal-title":"Crit. Rev. Immunol."},{"key":"10.1016\/j.ydbio.2015.11.023_bib20","doi-asserted-by":"crossref","first-page":"2432","DOI":"10.4049\/jimmunol.0901983","article-title":"Differential geminin requirement for proliferation of thymocytes and mature T cells","volume":"184","author":"Karamitros","year":"2010","journal-title":"J. Immunol."},{"key":"10.1016\/j.ydbio.2015.11.023_bib21","doi-asserted-by":"crossref","first-page":"3181","DOI":"10.4161\/cc.9.16.12554","article-title":"Life without geminin","volume":"9","author":"Karamitros","year":"2010","journal-title":"Cell Cycle"},{"key":"10.1016\/j.ydbio.2015.11.023_bib22","doi-asserted-by":"crossref","first-page":"70","DOI":"10.1242\/dev.109454","article-title":"Geminin deletion increases the number of fetal hematopoietic stem cells by affecting the expression of key transcription factors","volume":"142","author":"Karamitros","year":"2015","journal-title":"Development"},{"key":"10.1016\/j.ydbio.2015.11.023_bib23","doi-asserted-by":"crossref","first-page":"e25174","DOI":"10.1371\/journal.pone.0025174","article-title":"Aebp2 as an epigenetic regulator for neural crest cells","volume":"6","author":"Kim","year":"2011","journal-title":"PLoS One"},{"key":"10.1016\/j.ydbio.2015.11.023_bib24","doi-asserted-by":"crossref","first-page":"1395","DOI":"10.2741\/2156","article-title":"Geminin in embryonic development: coordinating transcription and the cell cycle during differentiation","volume":"12","author":"Kroll","year":"2007","journal-title":"Front. Biosci."},{"key":"10.1016\/j.ydbio.2015.11.023_bib25","doi-asserted-by":"crossref","first-page":"3247","DOI":"10.1242\/dev.125.16.3247","article-title":"Geminin, a neuralizing molecule that demarcates the future neural plate at the onset of gastrulation","volume":"125","author":"Kroll","year":"1998","journal-title":"Development"},{"key":"10.1016\/j.ydbio.2015.11.023_bib26","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1016\/S0925-4773(98)00105-1","article-title":"The winged helix transcription factor Hfh2 is expressed in neural crest and spinal cord during mouse development","volume":"76","author":"Labosky","year":"1998","journal-title":"Mech. Dev."},{"key":"10.1016\/j.ydbio.2015.11.023_bib27","doi-asserted-by":"crossref","first-page":"250","DOI":"10.1016\/j.jtbi.2011.01.043","article-title":"Building stable chains with motile agents: insights into the morphology of enteric neural crest cell migration","volume":"276","author":"Landman","year":"2011","journal-title":"J. Theor. Biol."},{"key":"10.1016\/j.ydbio.2015.11.023_bib28","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1016\/j.autneu.2009.09.001","article-title":"Enteric nervous system development: recent progress and future challenges","volume":"151","author":"Laranjeira","year":"2009","journal-title":"Auton. Neurosci.\u00a0\u2013 Basic Clin."},{"key":"10.1016\/j.ydbio.2015.11.023_bib29","series-title":"The Neural Crest","author":"Le Douarin","year":"1999"},{"key":"10.1016\/j.ydbio.2015.11.023_bib30","doi-asserted-by":"crossref","first-page":"1738","DOI":"10.1073\/pnas.1218072110","article-title":"Brg1 governs distinct pathways to direct multiple aspects of mammalian neural crest cell development","volume":"110","author":"Li","year":"2013","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.ydbio.2015.11.023_bib31","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1242\/dev.059824","article-title":"Geminin cooperates with Polycomb to restrain multi-lineage commitment in the early embryo","volume":"138","author":"Lim","year":"2011","journal-title":"Development"},{"key":"10.1016\/j.ydbio.2015.11.023_bib32","doi-asserted-by":"crossref","first-page":"527","DOI":"10.1016\/0896-6273(95)90142-6","article-title":"Postmigratory neural crest cells expressing c-RET display restricted developmental and proliferative capacities","volume":"15","author":"Lo","year":"1995","journal-title":"Neuron"},{"key":"10.1016\/j.ydbio.2015.11.023_bib33","doi-asserted-by":"crossref","first-page":"440","DOI":"10.1016\/S0960-9822(06)00191-6","article-title":"MASH1 maintains competence for BMP2-induced neuronal differentiation in post-migratory neural crest cells","volume":"7","author":"Lo","year":"1997","journal-title":"Curr. Biol."},{"key":"10.1016\/j.ydbio.2015.11.023_bib34","doi-asserted-by":"crossref","first-page":"749","DOI":"10.1038\/nature02305","article-title":"The cell-cycle regulator geminin inhibits Hox function through direct and polycomb-mediated interactions","volume":"427","author":"Luo","year":"2004","journal-title":"Nature"},{"issue":"968\u2013970","key":"10.1016\/j.ydbio.2015.11.023_bib35","first-page":"972","article-title":"PCR-based strategy for genotyping mice and ES cells harboring loxP sites","volume":"25","author":"Mantamadiotis","year":"1998","journal-title":"Biotechniques"},{"key":"10.1016\/j.ydbio.2015.11.023_bib36","doi-asserted-by":"crossref","first-page":"343","DOI":"10.1038\/nature09784","article-title":"The Polycomb complex PRC2 and its mark in life","volume":"469","author":"Margueron","year":"2011","journal-title":"Nature"},{"key":"10.1016\/j.ydbio.2015.11.023_bib37","doi-asserted-by":"crossref","first-page":"1043","DOI":"10.1016\/S0092-8674(00)81209-X","article-title":"Geminin, an inhibitor of DNA replication, is degraded during mitosis","volume":"93","author":"McGarry","year":"1998","journal-title":"Cell"},{"key":"10.1016\/j.ydbio.2015.11.023_bib38","doi-asserted-by":"crossref","first-page":"46826","DOI":"10.1074\/jbc.M406140200","article-title":"YY1 regulates the neural crest-associated slug gene in Xenopus laevis","volume":"279","author":"Morgan","year":"2004","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.ydbio.2015.11.023_bib39","doi-asserted-by":"crossref","first-page":"641","DOI":"10.1242\/dev.054718","article-title":"Neural crest stem cell multipotency requires Foxd3 to maintain neural potential and repress mesenchymal fates","volume":"138","author":"Mundell","year":"2011","journal-title":"Development"},{"key":"10.1016\/j.ydbio.2015.11.023_bib40","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1242\/dev.126.1.157","article-title":"Multipotential progenitors of the mammalian enteric nervous system capable of colonising aganglionic bowel in organ culture","volume":"126","author":"Natarajan","year":"1999","journal-title":"Development"},{"key":"10.1016\/j.ydbio.2015.11.023_bib41","doi-asserted-by":"crossref","first-page":"60","DOI":"10.1111\/dgd.12004","article-title":"Neural crest and somitic mesoderm as paradigms to investigate cell fate decisions during development","volume":"55","author":"Nitzan","year":"2013","journal-title":"Dev. Growth Differ."},{"key":"10.1016\/j.ydbio.2015.11.023_bib42","doi-asserted-by":"crossref","first-page":"10396","DOI":"10.1073\/pnas.0800672105","article-title":"Polycomb-group complex 1 acts as an E3 ubiquitin ligase for Geminin to sustain hematopoietic stem cell activity","volume":"105","author":"Ohtsubo","year":"2008","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.ydbio.2015.11.023_bib43","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1101\/sqb.2005.70.057","article-title":"Stem cell self-renewal and cancer cell proliferation are regulated by common networks that balance the activation of proto-oncogenes and tumor suppressors","volume":"70","author":"Pardal","year":"2005","journal-title":"Cold Spring Harb. Symp. Quant. Biol."},{"key":"10.1016\/j.ydbio.2015.11.023_bib44","doi-asserted-by":"crossref","first-page":"366","DOI":"10.1038\/20700","article-title":"The homeobox gene Phox2b is essential for the development of autonomic neural crest derivatives","volume":"399","author":"Pattyn","year":"1999","journal-title":"Nature"},{"key":"10.1016\/j.ydbio.2015.11.023_bib45","doi-asserted-by":"crossref","first-page":"445","DOI":"10.1101\/SQB.1996.061.01.047","article-title":"GDNF is required for kidney development and enteric innervation","volume":"61","author":"Pichel","year":"1996","journal-title":"Cold Spring Harb. Symp. Quant. Biol."},{"key":"10.1016\/j.ydbio.2015.11.023_bib46","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1016\/j.ydbio.2012.03.014","article-title":"Induction of the neural crest state: control of stem cell attributes by gene regulatory, post-transcriptional and epigenetic interactions","volume":"366","author":"Prasad","year":"2012","journal-title":"Dev. Biol."},{"key":"10.1016\/j.ydbio.2015.11.023_bib47","doi-asserted-by":"crossref","first-page":"2741","DOI":"10.1101\/gad.916201","article-title":"The Drosophila Geminin homolog: roles for Geminin in limiting DNA replication, in anaphase and in neurogenesis","volume":"15","author":"Quinn","year":"2001","journal-title":"Genes Dev."},{"key":"10.1016\/j.ydbio.2015.11.023_bib48","doi-asserted-by":"crossref","first-page":"9346","DOI":"10.1074\/jbc.M611643200","article-title":"Geminin cleavage during apoptosis by caspase-3 alters its binding ability to the SWI\/SNF subunit Brahma","volume":"282","author":"Roukos","year":"2007","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.ydbio.2015.11.023_bib49","doi-asserted-by":"crossref","first-page":"64","DOI":"10.1016\/j.ydbio.2012.01.012","article-title":"The enteric nervous system","volume":"366","author":"Sasselli","year":"2012","journal-title":"Dev. Biol."},{"key":"10.1016\/j.ydbio.2015.11.023_bib50","doi-asserted-by":"crossref","first-page":"557","DOI":"10.1038\/nrm2428","article-title":"A gene regulatory network orchestrates neural crest formation","volume":"9","author":"Sauka-Spengler","year":"2008","journal-title":"Nat. Rev. Mol. Cell Biol."},{"key":"10.1016\/j.ydbio.2015.11.023_bib51","doi-asserted-by":"crossref","first-page":"867","DOI":"10.1242\/dev.094342","article-title":"Ezh2 is required for neural crest-derived cartilage and bone formation","volume":"141","author":"Schwarz","year":"2014","journal-title":"Development"},{"key":"10.1016\/j.ydbio.2015.11.023_bib52","doi-asserted-by":"crossref","first-page":"1723","DOI":"10.1101\/gad.1319105","article-title":"Geminin regulates neuronal differentiation by antagonizing Brg1 activity","volume":"19","author":"Seo","year":"2005","journal-title":"Genes Dev."},{"key":"10.1016\/j.ydbio.2015.11.023_bib53","doi-asserted-by":"crossref","first-page":"553","DOI":"10.1016\/j.ydbio.2006.10.017","article-title":"Cell proliferation drives neural crest cell invasion of the intestine","volume":"302","author":"Simpson","year":"2007","journal-title":"Dev. Biol."},{"key":"10.1016\/j.ydbio.2015.11.023_bib54","doi-asserted-by":"crossref","first-page":"60","DOI":"10.1038\/ng0198-60","article-title":"Sox10 mutation disrupts neural crest development in Dom Hirschsprung mouse model","volume":"18","author":"Southard-Smith","year":"1998","journal-title":"Nat. Genet."},{"key":"10.1016\/j.ydbio.2015.11.023_bib55","doi-asserted-by":"crossref","first-page":"1269","DOI":"10.1002\/stem.678","article-title":"Geminin regulates cortical progenitor proliferation and differentiation","volume":"29","author":"Spella","year":"2011","journal-title":"Stem Cells"},{"key":"10.1016\/j.ydbio.2015.11.023_bib56","doi-asserted-by":"crossref","first-page":"373","DOI":"10.1016\/j.neuroscience.2007.03.050","article-title":"Licensing regulators Geminin and Cdt1 identify progenitor cells of the mouse CNS in a specific phase of the cell cycle","volume":"147","author":"Spella","year":"2007","journal-title":"Neuroscience"},{"key":"10.1016\/j.ydbio.2015.11.023_bib57","doi-asserted-by":"crossref","first-page":"4","DOI":"10.1186\/1471-213X-1-4","article-title":"Cre reporter strains produced by targeted insertion of EYFP and ECFP into the ROSA26 locus","volume":"1","author":"Srinivas","year":"2001","journal-title":"BMC Dev. Biol."},{"key":"10.1016\/j.ydbio.2015.11.023_bib58","doi-asserted-by":"crossref","first-page":"973","DOI":"10.1016\/0092-8674(92)90393-Q","article-title":"Isolation of a stem cell for neurons and glia from the mammalian neural crest","volume":"71","author":"Stemple","year":"1992","journal-title":"Cell"},{"key":"10.1016\/j.ydbio.2015.11.023_bib59","doi-asserted-by":"crossref","first-page":"2803","DOI":"10.1016\/j.febslet.2012.07.042","article-title":"Control over DNA replication in time and space","volume":"586","author":"Symeonidou","year":"2012","journal-title":"FEBS Lett."},{"key":"10.1016\/j.ydbio.2015.11.023_bib60","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1038\/35055000","article-title":"Repression of origin assembly in metaphase depends on inhibition of RLF-B\/Cdt1 by geminin","volume":"3","author":"Tada","year":"2001","journal-title":"Nat. Cell Biol."},{"key":"10.1016\/j.ydbio.2015.11.023_bib61","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1016\/S0959-437X(99)80048-3","article-title":"Development of the mammalian enteric nervous system","volume":"9","author":"Taraviras","year":"1999","journal-title":"Curr. Opin. Genet. Dev."},{"key":"10.1016\/j.ydbio.2015.11.023_bib62","doi-asserted-by":"crossref","first-page":"2785","DOI":"10.1242\/dev.126.12.2785","article-title":"Signalling by the RET receptor tyrosine kinase and its role in the development of the mammalian enteric nervous system","volume":"126","author":"Taraviras","year":"1999","journal-title":"Development"},{"key":"10.1016\/j.ydbio.2015.11.023_bib63","doi-asserted-by":"crossref","first-page":"1615","DOI":"10.1242\/dev.012179","article-title":"Requirement for Foxd3 in the maintenance of neural crest progenitors","volume":"135","author":"Teng","year":"2008","journal-title":"Development"},{"key":"10.1016\/j.ydbio.2015.11.023_bib64","doi-asserted-by":"crossref","first-page":"722","DOI":"10.1242\/dev.111997","article-title":"Snail2\/Slug cooperates with Polycomb repressive complex 2 (PRC2) to regulate neural crest development","volume":"142","author":"Tien","year":"2015","journal-title":"Development"},{"key":"10.1016\/j.ydbio.2015.11.023_bib65","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1016\/S0925-4773(00)00457-3","article-title":"Regulation of Hoxb3 expression in the hindbrain and pharyngeal arches by rae28, a member of the mammalian Polycomb group of genes","volume":"98","author":"Tomotsune","year":"2000","journal-title":"Mech. Dev."},{"key":"10.1016\/j.ydbio.2015.11.023_bib66","doi-asserted-by":"crossref","first-page":"2309","DOI":"10.1126\/science.290.5500.2309","article-title":"Inhibition of eukaryotic DNA replication by geminin binding to Cdt1","volume":"290","author":"Wohlschlegel","year":"2000","journal-title":"Science"},{"key":"10.1016\/j.ydbio.2015.11.023_bib67","doi-asserted-by":"crossref","first-page":"3368","DOI":"10.1111\/j.1432-1033.2004.04271.x","article-title":"Cdt1 and geminin are down-regulated upon cell cycle exit and are over-expressed in cancer-derived cell lines","volume":"271","author":"Xouri","year":"2004","journal-title":"Eur. J. Biochem."},{"key":"10.1016\/j.ydbio.2015.11.023_bib68","doi-asserted-by":"crossref","first-page":"515","DOI":"10.1002\/cne.901010212","article-title":"The origin of intrinsic ganglia of trunk viscera from vagal neural crest in the chick embryo","volume":"101","author":"Yntema","year":"1954","journal-title":"J. Comp. Neurol."},{"key":"10.1016\/j.ydbio.2015.11.023_bib69","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1002\/cne.10448","article-title":"Acquisition of neuronal and glial markers by neural crest-derived cells in the mouse intestine","volume":"456","author":"Young","year":"2003","journal-title":"J. Comp. Neurol."},{"key":"10.1016\/j.ydbio.2015.11.023_bib70","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/s00441-004-1057-5","article-title":"The location and phenotype of proliferating neural-crest-derived cells in the developing mouse gut","volume":"320","author":"Young","year":"2005","journal-title":"Cell Tissue Res."},{"key":"10.1016\/j.ydbio.2015.11.023_bib71","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1006\/dbio.1998.8987","article-title":"A single rostrocaudal colonization of the rodent intestine by enteric neuron precursors is revealed by the expression of Phox2b, Ret, and p75 and by explants grown under the kidney capsule or in organ culture","volume":"202","author":"Young","year":"1998","journal-title":"Dev. Biol."},{"key":"10.1016\/j.ydbio.2015.11.023_bib72","doi-asserted-by":"crossref","first-page":"455","DOI":"10.1016\/j.ydbio.2004.03.015","article-title":"Dynamics of neural crest-derived cell migration in the embryonic mouse gut","volume":"270","author":"Young","year":"2004","journal-title":"Dev. Biol."}],"container-title":["Developmental Biology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0012160615301652?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0012160615301652?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2022,5,28]],"date-time":"2022-05-28T10:17:24Z","timestamp":1653733044000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0012160615301652"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,1]]},"references-count":72,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2016,1]]}},"alternative-id":["S0012160615301652"],"URL":"https:\/\/doi.org\/10.1016\/j.ydbio.2015.11.023","relation":{},"ISSN":["0012-1606"],"issn-type":[{"value":"0012-1606","type":"print"}],"subject":[],"published":{"date-parts":[[2016,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Inactivation of Geminin in neural crest cells affects the generation and maintenance of enteric progenitor cells, leading to enteric aganglionosis","name":"articletitle","label":"Article Title"},{"value":"Developmental Biology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ydbio.2015.11.023","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2015 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}