{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,16]],"date-time":"2026-04-16T00:21:50Z","timestamp":1776298910761,"version":"3.50.1"},"reference-count":35,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2018,9,1]],"date-time":"2018-09-01T00:00:00Z","timestamp":1535760000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2018,9,1]],"date-time":"2018-09-01T00:00:00Z","timestamp":1535760000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2019,9,15]],"date-time":"2019-09-15T00:00:00Z","timestamp":1568505600000},"content-version":"vor","delay-in-days":379,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/100011796","name":"Mount Saint Vincent University","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100011796","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000038","name":"Natural Sciences and Engineering Research Council of Canada","doi-asserted-by":"publisher","award":["328376"],"award-info":[{"award-number":["328376"]}],"id":[{"id":"10.13039\/501100000038","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000038","name":"Natural Sciences and Engineering Research Council of Canada","doi-asserted-by":"publisher","award":["WISU413497"],"award-info":[{"award-number":["WISU413497"]}],"id":[{"id":"10.13039\/501100000038","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100009989","name":"Nova Scotia Research Innovation Trust","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100009989","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Developmental Biology"],"published-print":{"date-parts":[[2018,9]]},"DOI":"10.1016\/j.ydbio.2018.07.008","type":"journal-article","created":{"date-parts":[[2018,7,11]],"date-time":"2018-07-11T12:51:01Z","timestamp":1531313461000},"page":"235-241","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":15,"title":["Genetic linkage between altered tooth and eye development in lens-ablated Astyanax mexicanus"],"prefix":"10.1016","volume":"441","author":[{"given":"Atukorallaya Devi Sewvandini","family":"Atukorala","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tamara Anne","family":"Franz-Odendaal","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.ydbio.2018.07.008_bib1","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1186\/2041-9139-4-28","article-title":"Adaptive evolution of the lower jaw dentition in Mexican tetra (Astyanax mexicanus)","volume":"4","author":"Atukorala","year":"2013","journal-title":"Evodevo"},{"key":"10.1016\/j.ydbio.2018.07.008_bib2","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1016\/j.mod.2014.09.002","article-title":"Spatial and temporal events in tooth development of Astyanax mexicanus","volume":"134","author":"Atukorala","year":"2014","journal-title":"Mech. Dev."},{"key":"10.1016\/j.ydbio.2018.07.008_bib3","series-title":"Biology and Evolution of the MexicanCavefish","first-page":"209","article-title":"Evolution and develoment of the cavefish oral jaws: adaptations for feeding","author":"Atukorala","year":"2015"},{"key":"10.1016\/j.ydbio.2018.07.008_bib4","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1167\/iovs.11-8494","article-title":"A zebrafish model of Axenfeld-Rieger Syndrome reveals that pitx2 regulation by retinoic acid is essential for ocular and craniofacial development","volume":"53","author":"Bohnsack","year":"2012","journal-title":"Investig. Ophthalmol. Vis. Sci."},{"key":"10.1016\/j.ydbio.2018.07.008_bib5","doi-asserted-by":"crossref","first-page":"1974","DOI":"10.1177\/00220345010800110501","article-title":"Sonic hedgehog regulates epithelial proliferation and cell survival in the developing tooth germ","volume":"80","author":"Cobourne","year":"2001","journal-title":"J. Dent. Res."},{"key":"10.1016\/j.ydbio.2018.07.008_bib6","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/S0003-9969(02)00208-X","article-title":"Tooth and jaw: molecular mechanisms of patterning in the first branchial arch","volume":"48","author":"Cobourne","year":"2003","journal-title":"Arch. Oral. Biol."},{"key":"10.1016\/j.ydbio.2018.07.008_bib7","doi-asserted-by":"crossref","first-page":"e50308","DOI":"10.1371\/journal.pone.0050308","article-title":"Early lens ablation causes dramatic long-term effects on the shape of bones in the craniofacial skeleton of Astyanax mexicanus","volume":"7","author":"Dufton","year":"2012","journal-title":"PLoS One"},{"issue":"9","key":"10.1016\/j.ydbio.2018.07.008_bib8","doi-asserted-by":"crossref","first-page":"1109","DOI":"10.1002\/dvdy.24278","article-title":"Morphological diversity in the orbital bones of two teleosts with experimental and natural variation in eye size","volume":"244","author":"Dufton","year":"2015","journal-title":"Dev. Dyn."},{"issue":"1","key":"10.1016\/j.ydbio.2018.07.008_bib9","doi-asserted-by":"crossref","first-page":"94","DOI":"10.1111\/j.1525-142X.2006.05078.x","article-title":"Modularity and sense organs in the blind cavefish, Astyanax mexicanus","volume":"8","author":"Franz-Odendaal","year":"2006","journal-title":"Evol. Dev."},{"key":"10.1016\/j.ydbio.2018.07.008_bib10","doi-asserted-by":"crossref","first-page":"266","DOI":"10.14219\/jada.archive.1978.0054","article-title":"Congenital absence of teeth: a review with emphasis on inheritance patterns","volume":"96","author":"Graber","year":"1978","journal-title":"J. Am. Dent. Assoc."},{"issue":"6","key":"10.1016\/j.ydbio.2018.07.008_bib11","doi-asserted-by":"crossref","first-page":"265","DOI":"10.3727\/000000001783992515","article-title":"Antagonistic regulation of Dlx2 expression by Pitx2 and MSx2: implications for tooth development","volume":"9","author":"Green","year":"2001","journal-title":"Gene Expr."},{"key":"10.1016\/j.ydbio.2018.07.008_bib12","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1111\/ceo.12152","article-title":"Genomics and anterior segment dysgenesis: a review","volume":"42","author":"Ito","year":"2014","journal-title":"Clin. Exp. Ophthalmol."},{"key":"10.1016\/j.ydbio.2018.07.008_bib13","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1006\/dbio.2000.0121","article-title":"Cavefish as a model system in evolutionary developmental biology","volume":"231","author":"Jeffery","year":"2001","journal-title":"Dev. Biol."},{"key":"10.1016\/j.ydbio.2018.07.008_bib14","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1146\/annurev-genet-102108-134216","article-title":"Regressive evolution in Astyanax cavefish","volume":"43","author":"Jeffery","year":"2009","journal-title":"Annu. Rev. Genet."},{"key":"10.1016\/j.ydbio.2018.07.008_bib15","series-title":"Biology and Evolution of the Mexican Cavefish","author":"Keene","year":"2015"},{"key":"10.1016\/j.ydbio.2018.07.008_bib16","doi-asserted-by":"crossref","first-page":"194","DOI":"10.1093\/hmg\/ddt411","article-title":"A model for the molecular underpinnings of tooth defects in Axenfeld-Rieger syndrome","volume":"23","author":"Li","year":"2014","journal-title":"Hum. Mol. Genet."},{"key":"10.1016\/j.ydbio.2018.07.008_bib17","doi-asserted-by":"crossref","first-page":"e30896","DOI":"10.1371\/journal.pone.0030896","article-title":"pitx2 Deficiency results in abnormal ocular and craniofacial development in zebrafish","volume":"7","author":"Liu","year":"2012","journal-title":"PLoS One"},{"key":"10.1016\/j.ydbio.2018.07.008_bib18","doi-asserted-by":"crossref","first-page":"5307","DOI":"10.1038\/ncomms6307","article-title":"The cavefish genome reveals candidate genes for eye loss","volume":"5","author":"McGaugh","year":"2014","journal-title":"Nat. Commun."},{"key":"10.1016\/j.ydbio.2018.07.008_bib19","doi-asserted-by":"crossref","first-page":"2467","DOI":"10.1242\/dev.054106","article-title":"Restoring eye size in Astyanax mexicanus blind cavefish embryos through modulation of the Shh and Fgf8 forebrain organising centres","volume":"138","author":"Pottin","year":"2011","journal-title":"Development"},{"key":"10.1016\/j.ydbio.2018.07.008_bib20","series-title":"Biology and Evolution of the MexicanCavefish","first-page":"227","article-title":"Neural Development and Evolution in Astyanax mexicanus: comparing Cavefish and Surface Fish Brains","author":"R\u00e9taux","year":"2015"},{"key":"10.1016\/j.ydbio.2018.07.008_bib21","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1016\/S0925-4773(99)00095-7","article-title":"Expression of Wnt signalling pathway genes during tooth development","volume":"85","author":"Sarkar","year":"1999","journal-title":"Mech. Dev."},{"key":"10.1016\/j.ydbio.2018.07.008_bib22","doi-asserted-by":"crossref","first-page":"515","DOI":"10.1002\/jez.b.22749","article-title":"A Comparative transcriptomic analysis of development in two Astyanax cavefish populations","volume":"328","author":"Stahl","year":"2017","journal-title":"J. Exp. Zool. Part B"},{"key":"10.1016\/j.ydbio.2018.07.008_bib23","doi-asserted-by":"crossref","first-page":"3127","DOI":"10.1242\/dev.02459","article-title":"Developmental genetic mechanisms of evolutionary tooth loss in cypriniform fishes","volume":"133","author":"Stock","year":"2006","journal-title":"Development"},{"key":"10.1016\/j.ydbio.2018.07.008_bib24","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1038\/nprot.2007.514","article-title":"High-resolution in situ hybridization to whole-mount zebrafish embryos","volume":"3","author":"Thisse","year":"2008","journal-title":"Nat. Protoc."},{"key":"10.1016\/j.ydbio.2018.07.008_bib25","doi-asserted-by":"crossref","first-page":"523","DOI":"10.1111\/j.1096-3642.2005.00193.x","article-title":"Ontogenetic transition from unicuspid to multicuspid oral dentition in a teleost fish: Astyanax mexicanus, the Mexican tetra (Ostariophysi: characidae)","volume":"145","author":"Trapani","year":"2005","journal-title":"Zool. J. Linn. Soc."},{"key":"10.1016\/j.ydbio.2018.07.008_bib26","doi-asserted-by":"crossref","first-page":"499","DOI":"10.1038\/nrg1380","article-title":"The cutting-edge of mammalian development; how the embryo makes teeth","volume":"5","author":"Tucker","year":"2004","journal-title":"Nat. Rev. Genet."},{"key":"10.1016\/j.ydbio.2018.07.008_bib27","first-page":"b115","article-title":"Hypodontia and microdontia: clinical features of a rare syndrome","volume":"77","author":"Villa","year":"2011","journal-title":"J. Can. Dent. Assoc."},{"key":"10.1016\/j.ydbio.2018.07.008_bib28","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1080\/10520290701333558","article-title":"A two-color acid-free cartilage and bone stain for zebrafish larvae","volume":"82","author":"Walker","year":"2007","journal-title":"Biotech. Histochem."},{"key":"10.1016\/j.ydbio.2018.07.008_bib29","doi-asserted-by":"crossref","first-page":"287","DOI":"10.1111\/j.1095-8312.2007.00840.x","article-title":"Regressive evolution: ontogeny and genetics of cavefish eye rudimentation","volume":"92","author":"Wilkens","year":"2007","journal-title":"Biol. J. Linn. Soc."},{"key":"10.1016\/j.ydbio.2018.07.008_bib30","doi-asserted-by":"crossref","first-page":"511","DOI":"10.1111\/j.1525-142X.2006.00124.x","article-title":"Conservation and divergence of Bmp2a, Bmp2b, and Bmp4 expression patterns within and between dentitions of teleost fishes","volume":"8","author":"Wise","year":"2006","journal-title":"Evol. Dev."},{"key":"10.1016\/j.ydbio.2018.07.008_bib31","doi-asserted-by":"crossref","first-page":"2534","DOI":"10.1002\/dvdy.22411","article-title":"bmp2b and bmp4 are dispensable for zebrafish tooth development","volume":"239","author":"Wise","year":"2010","journal-title":"Dev. Dyn."},{"key":"10.1016\/j.ydbio.2018.07.008_bib32","doi-asserted-by":"crossref","first-page":"200","DOI":"10.1016\/j.ydbio.2009.03.003","article-title":"Pleiotropic functions of embryonic sonic hedgehog expression link jaw and taste bud amplification with eye loss during cavefish evolution","volume":"330","author":"Yamamoto","year":"2009","journal-title":"Dev. Biol."},{"key":"10.1016\/j.ydbio.2018.07.008_bib33","doi-asserted-by":"crossref","first-page":"435","DOI":"10.1046\/j.1525-142X.2003.03050.x","article-title":"Development and evolution of craniofacial patterning is mediated by eye-dependent and -independent processes in the cavefish Astyanax","volume":"5","author":"Yamamoto","year":"2003","journal-title":"Evol. Dev."},{"key":"10.1016\/j.ydbio.2018.07.008_bib34","doi-asserted-by":"crossref","first-page":"631","DOI":"10.1126\/science.289.5479.631","article-title":"Central role for the lens in cave fish eye degeneration","volume":"289","author":"Yamamoto","year":"2000","journal-title":"Science"},{"key":"10.1016\/j.ydbio.2018.07.008_bib35","doi-asserted-by":"crossref","first-page":"420","DOI":"10.1016\/S1046-2023(02)00261-X","article-title":"Probing teleost eye development by lens transplantation","volume":"28","author":"Yamamoto","year":"2002","journal-title":"Methods"}],"container-title":["Developmental Biology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0012160618300666?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0012160618300666?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,2]],"date-time":"2025-11-02T22:48:49Z","timestamp":1762123729000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0012160618300666"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,9]]},"references-count":35,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2018,9]]}},"alternative-id":["S0012160618300666"],"URL":"https:\/\/doi.org\/10.1016\/j.ydbio.2018.07.008","relation":{},"ISSN":["0012-1606"],"issn-type":[{"value":"0012-1606","type":"print"}],"subject":[],"published":{"date-parts":[[2018,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Genetic linkage between altered tooth and eye development in lens-ablated Astyanax mexicanus","name":"articletitle","label":"Article Title"},{"value":"Developmental Biology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ydbio.2018.07.008","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2018 Elsevier Inc.","name":"copyright","label":"Copyright"}]}}