{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,16]],"date-time":"2025-09-16T20:31:43Z","timestamp":1758054703749,"version":"3.44.0"},"reference-count":51,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2020,2,1]],"date-time":"2020-02-01T00:00:00Z","timestamp":1580515200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,2,1]],"date-time":"2020-02-01T00:00:00Z","timestamp":1580515200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2021,2,15]],"date-time":"2021-02-15T00:00:00Z","timestamp":1613347200000},"content-version":"vor","delay-in-days":380,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"funder":[{"name":"Nippon Shinyaku Research"},{"DOI":"10.13039\/501100001691","name":"JSPS KAKENHI, Japan","doi-asserted-by":"publisher","award":["JP26461619","JP16H05359"],"award-info":[{"award-number":["JP26461619","JP16H05359"]}],"id":[{"id":"10.13039\/501100001691","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Developmental Biology"],"published-print":{"date-parts":[[2020,2]]},"DOI":"10.1016\/j.ydbio.2019.11.011","type":"journal-article","created":{"date-parts":[[2019,11,20]],"date-time":"2019-11-20T11:11:38Z","timestamp":1574248298000},"page":"237-245","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":2,"title":["Inositol 1,4,5-trisphosphate receptor 2 as a novel marker of vasculature to delineate processes of cardiopulmonary development"],"prefix":"10.1016","volume":"458","author":[{"given":"Reina","family":"Ishizaki-Asami","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Keiko","family":"Uchida","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Takatoshi","family":"Tsuchihashi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Akimichi","family":"Shibata","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kazuki","family":"Kodo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Katsura","family":"Emoto","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Katsuhiko","family":"Mikoshiba","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Takao","family":"Takahashi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hiroyuki","family":"Yamagishi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.ydbio.2019.11.011_bib1","first-page":"9","article-title":"The fate of the outflow tract septal complex in relation to the classification of ventricular septal defects","volume":"6","author":"Anderson","year":"2019","journal-title":"J.\u00a0Cardiovasc. Dev. Dis."},{"key":"10.1016\/j.ydbio.2019.11.011_bib2","doi-asserted-by":"crossref","first-page":"e1","DOI":"10.1161\/CIR.0000000000000659","article-title":"Heart disease and stroke statistics \u2014 2019 update A report from the American heart association","volume":"139","author":"Benjamin","year":"2019","journal-title":"Circulation"},{"key":"10.1016\/j.ydbio.2019.11.011_bib3","doi-asserted-by":"crossref","first-page":"379","DOI":"10.1002\/(SICI)1097-0177(199608)206:4<379::AID-AJA4>3.0.CO;2-F","article-title":"Expression of the T-box family genes , Tbxl-Tbx5 , during early mouse development","volume":"206","author":"Chapman","year":"1996","journal-title":"Dev. Dynam."},{"key":"10.1016\/j.ydbio.2019.11.011_bib4","doi-asserted-by":"crossref","first-page":"568","DOI":"10.1165\/ajrcmb.16.5.9160839","article-title":"Early fetal development of lung vasculature","volume":"16","author":"deMello","year":"1997","journal-title":"Am. J. Respir. Cell Mol. Biol."},{"key":"10.1016\/j.ydbio.2019.11.011_bib5","doi-asserted-by":"crossref","first-page":"4398","DOI":"10.1242\/dev.098079","article-title":"Derivation of lung mesenchymal lineages from the fetal mesothelium requires hedgehog signaling for mesothelial cell entry","volume":"140","author":"Dixit","year":"2013","journal-title":"Development"},{"key":"10.1016\/j.ydbio.2019.11.011_bib6","doi-asserted-by":"crossref","first-page":"296","DOI":"10.1242\/dev.099747","article-title":"Fgf10-positive cells represent a progenitor cell population during lung development and postnatally","volume":"141","author":"El Agha","year":"2014","journal-title":"Development"},{"key":"10.1016\/j.ydbio.2019.11.011_bib7","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0006049","article-title":"Tbx1 regulates the BMP-smad1 pathway in a transcription independent manner","volume":"4","author":"Fulcoli","year":"2009","journal-title":"PLoS One"},{"key":"10.1016\/j.ydbio.2019.11.011_bib8","doi-asserted-by":"crossref","first-page":"2232","DOI":"10.1126\/science.1114110","article-title":"IP3 receptor types 2 and 3 mediate exocrine secretion underlying energy metabolism","volume":"309","author":"Futatsugi","year":"2005","journal-title":"Science"},{"key":"10.1016\/j.ydbio.2019.11.011_bib9","doi-asserted-by":"crossref","first-page":"7058","DOI":"10.1073\/pnas.1007293108","article-title":"Follistatin-like 1 (Fstl1) is a bone morphogenetic protein (BMP) 4 signaling antagonist in controlling mouse lung development","volume":"108","author":"Geng","year":"2011","journal-title":"Pnas"},{"key":"10.1016\/j.ydbio.2019.11.011_bib10","doi-asserted-by":"crossref","first-page":"482","DOI":"10.1016\/j.devcel.2012.07.009","article-title":"Radial construction of an arterial wall","volume":"23","author":"Greif","year":"2012","journal-title":"Dev. Cell"},{"key":"10.1016\/j.ydbio.2019.11.011_bib11","doi-asserted-by":"crossref","first-page":"862","DOI":"10.1002\/dvg.22721","article-title":"Nkx2-5 lineage tracing visualizes the distribution of second heart field-derived aortic smooth muscle","volume":"51","author":"Harmon","year":"2013","journal-title":"Genesis"},{"key":"10.1016\/j.ydbio.2019.11.011_bib12","first-page":"15","article-title":"Development of pharyngeal arch arteries in early mouse embryo","volume":"201","author":"Hiruma","year":"2002","journal-title":"J.\u00a0Anat."},{"key":"10.1016\/j.ydbio.2019.11.011_bib13","doi-asserted-by":"crossref","first-page":"5491","DOI":"10.1242\/dev.01399","article-title":"Tbx1 regulates fibroblast growth factors in the anterior heart field through a reinforcing autoregulatory loop involving forkhead transcription factors","volume":"131","author":"Hu","year":"2004","journal-title":"Development"},{"key":"10.1016\/j.ydbio.2019.11.011_bib14","doi-asserted-by":"crossref","first-page":"470","DOI":"10.1002\/dvg.20317","article-title":"A\u00a0fate map of Tbx1 expressing cells reveals heterogeneity in the second cardiac field","volume":"45","author":"Huynh","year":"2007","journal-title":"Genesis"},{"key":"10.1016\/j.ydbio.2019.11.011_bib15","doi-asserted-by":"crossref","first-page":"1607","DOI":"10.1242\/dev.127.8.1607","article-title":"Fate of the mammalian cardiac neural crest","volume":"127","author":"Jiang","year":"2000","journal-title":"Development"},{"key":"10.1016\/j.ydbio.2019.11.011_bib16","doi-asserted-by":"crossref","first-page":"435","DOI":"10.1016\/S1534-5807(01)00040-5","article-title":"The arterial pole of the mouse heart forms from Fgf10-expressing cells in pharyngeal mesoderm","volume":"1","author":"Kelly","year":"2001","journal-title":"Dev. Cell"},{"key":"10.1016\/j.ydbio.2019.11.011_bib17","doi-asserted-by":"crossref","first-page":"821","DOI":"10.1002\/dvdy.21063","article-title":"Visualization of outflow tract development in the absence of Tbx1 using an Fgf10 enhancer trap transgene","volume":"236","author":"Kelly","year":"2007","journal-title":"Dev. Dynam."},{"key":"10.1016\/j.ydbio.2019.11.011_bib18","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1002\/bdrc.21076","article-title":"Evolutionary and developmental origins of the cardiac neural crest: building a divided outflow tract","volume":"102","author":"Keyte","year":"2014","journal-title":"Birth Defects Res. Part C"},{"key":"10.1016\/j.ydbio.2019.11.011_bib19","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1038\/s41598-017-06964-9","article-title":"Regulation of Sema3c and the interaction between cardiac neural crest and second heart field during outflow tract development","volume":"7","author":"Kodo","year":"2017","journal-title":"Sci. Rep."},{"key":"10.1016\/j.ydbio.2019.11.011_bib20","doi-asserted-by":"crossref","first-page":"999","DOI":"10.1002\/stem.1911","article-title":"Progenitors of secondary crest myofibroblasts are developmentally committed in early lung mesoderm","volume":"33","author":"Li","year":"2015","journal-title":"Stem Cells"},{"key":"10.1016\/j.ydbio.2019.11.011_bib21","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1152\/ajplung.00391.2015","article-title":"BMP signaling is essential in neonatal surfactant production during respiratory adaptation","volume":"311","author":"Luo","year":"2016","journal-title":"Am. J. Physiol. Lung Cell Mol. Physiol."},{"key":"10.1016\/j.ydbio.2019.11.011_bib22","doi-asserted-by":"crossref","first-page":"701","DOI":"10.1002\/dvdy.20686","article-title":"Tbx1 is regulated by forkhead proteins in the secondary heart field","volume":"235","author":"Maeda","year":"2006","journal-title":"Dev. Dynam."},{"key":"10.1016\/j.ydbio.2019.11.011_bib23","doi-asserted-by":"crossref","first-page":"2157","DOI":"10.1242\/dev.01795","article-title":"Fgf10 expression identifies parabronchial smooth muscle cell progenitors and is required for their entry into the smooth muscle cell lineage","volume":"132","author":"Mailleux","year":"2005","journal-title":"Development"},{"key":"10.1016\/j.ydbio.2019.11.011_bib24","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0211170","article-title":"Left pulmonary artery in 22q11.2 deletion syndrome. Echocardiographic evaluation in patients without cardiac defects and role of Tbx1 in mice","volume":"14","author":"Mastromoro","year":"2019","journal-title":"PLoS One"},{"key":"10.1016\/j.ydbio.2019.11.011_bib25","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1016\/j.jbior.2014.10.001","article-title":"Role of IP3 receptor signaling in cell functions and diseases","volume":"57","author":"Mikoshiba","year":"2015","journal-title":"Adv. Biol. Regul."},{"key":"10.1016\/j.ydbio.2019.11.011_bib26","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1006\/dbio.2001.0409","article-title":"The outflow tract of the heart is recruited from a novel heart-forming field","volume":"238","author":"Mjaatvedt","year":"2001","journal-title":"Dev. Biol."},{"key":"10.1016\/j.ydbio.2019.11.011_bib27","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1016\/j.devcel.2009.12.010","article-title":"Preparing for the first Breath\u00a0\u200b: genetic and cellular mechanisms in lung development","volume":"18","author":"Morrisey","year":"2010","journal-title":"Dev. Cell"},{"key":"10.1016\/j.ydbio.2019.11.011_bib28","doi-asserted-by":"crossref","first-page":"58","DOI":"10.1016\/j.yjmcc.2011.02.014","article-title":"Inositol 1,4,5-trisphosphate receptors are essential for the development of the second heart field","volume":"51","author":"Nakazawa","year":"2011","journal-title":"J.\u00a0Mol. Cell. Cardiol."},{"key":"10.1016\/j.ydbio.2019.11.011_bib29","doi-asserted-by":"crossref","first-page":"L141","DOI":"10.1152\/ajplung.00148.2004","article-title":"Distal angiogenesis\u00a0\u200b: a new concept for lung vascular morphogenesis","volume":"288","author":"Parera","year":"2005","journal-title":"Am. J. Physiol. Lung Cell Mol. Physiol."},{"key":"10.1016\/j.ydbio.2019.11.011_bib30","doi-asserted-by":"crossref","first-page":"589","DOI":"10.1038\/nature12358","article-title":"Coordination of heart and lung co-development by a multipotent cardiopulmonary progenitor","volume":"500","author":"Peng","year":"2013","journal-title":"Nature"},{"key":"10.1016\/j.ydbio.2019.11.011_bib31","doi-asserted-by":"crossref","first-page":"16626","DOI":"10.1073\/pnas.0808649105","article-title":"Mesothelium contributes to vascular smooth muscle and mesenchyme during lung development","volume":"105","author":"Que","year":"2008","journal-title":"Proc. Natl. Acad. Sci."},{"key":"10.1016\/j.ydbio.2019.11.011_bib32","doi-asserted-by":"crossref","first-page":"790","DOI":"10.1161\/CIRCRESAHA.115.305020","article-title":"Tbx1 coordinates addition of posterior second heart field progenitor cells to the arterial and venous poles of the heart","volume":"115","author":"Rana","year":"2014","journal-title":"Circ. Res."},{"key":"10.1016\/j.ydbio.2019.11.011_bib33","doi-asserted-by":"crossref","first-page":"L743","DOI":"10.1152\/ajplung.00146.2004","article-title":"Surfactant lipid synthesis and lamellar body formation in glycogen-laden type II cells","volume":"287","author":"Ridsdale","year":"2004","journal-title":"Am. J. Physiol. Lung Cell Mol. Physiol."},{"key":"10.1016\/j.ydbio.2019.11.011_bib34","series-title":"Theory and Practice of Histological Techniques","first-page":"585","article-title":"Electron microscopy 2: practical procedures","author":"Robinson","year":"1996"},{"key":"10.1016\/j.ydbio.2019.11.011_bib35","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1016\/j.ijporl.2017.02.012","article-title":"Association of airway abnormalities with 22q11.2 deletion syndrome","volume":"96","author":"Sacca","year":"2017","journal-title":"Int. J. Pediatr. Otorhinolaryngol."},{"key":"10.1016\/j.ydbio.2019.11.011_bib36","doi-asserted-by":"crossref","first-page":"395","DOI":"10.1177\/0192623309335060","article-title":"Histology atlas of the developing mouse heart with emphasis on E11.5 to E18.5","volume":"37","author":"Savolainen","year":"2009","journal-title":"Toxicol. Pathol."},{"key":"10.1016\/j.ydbio.2019.11.011_bib37","doi-asserted-by":"crossref","first-page":"1722","DOI":"10.1161\/ATVBAHA.117.309599","article-title":"Smooth muscle cells derived from second heart field and cardiac neural crest reside in spatially distinct domains in the media of the ascending aorta - brief report","volume":"37","author":"Sawada","year":"2017","journal-title":"Arterioscler. Thromb. Vasc. Biol."},{"key":"10.1016\/j.ydbio.2019.11.011_bib38","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1165\/ajrcmb.22.2.3766","article-title":"Qualitative and quantitative analysis of embryonic pulmonary vessel formation","volume":"22","author":"Schachtner","year":"2000","journal-title":"Am. J. Respir. Cell Mol. Biol."},{"key":"10.1016\/j.ydbio.2019.11.011_bib39","doi-asserted-by":"crossref","first-page":"1413","DOI":"10.1002\/dvdy.23833","article-title":"Morphogenesis of outflow tract rotation during cardiac development: the pulmonary push concept","volume":"241","author":"Scherptong","year":"2012","journal-title":"Dev. Dynam."},{"key":"10.1016\/j.ydbio.2019.11.011_bib40","doi-asserted-by":"crossref","first-page":"724","DOI":"10.1007\/s00380-018-1304-4","article-title":"Type 2 inositol 1,4,5-trisphosphate receptor inhibits the progression of pulmonary arterial hypertension via calcium signaling and apoptosis","volume":"34","author":"Shibata","year":"2019","journal-title":"Heart Vessel."},{"key":"10.1016\/j.ydbio.2019.11.011_bib41","doi-asserted-by":"crossref","first-page":"142","DOI":"10.1161\/CIRCRESAHA.108.172189","article-title":"The del22q11.2 candidate gene tbx1 controls regional outflow tract identity and coronary artery patterning","volume":"103","author":"Th\u00e9veniau-Ruissy","year":"2008","journal-title":"Circ. Res."},{"key":"10.1016\/j.ydbio.2019.11.011_bib42","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1002\/dvdy.1124","article-title":"Spatial and temporal distribution of nerves, ganglia, and smooth muscle during the early pseudoglandular stage of fetal mouse lung development","volume":"221","author":"Tollet","year":"2001","journal-title":"Dev. Dynam."},{"key":"10.1016\/j.ydbio.2019.11.011_bib43","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0012500","article-title":"Gene knock-outs of inositol 1,4,5-trisphosphate receptors types 1 and 2 result in perturbation of cardiogenesis","volume":"5","author":"Uchida","year":"2010","journal-title":"PLoS One"},{"key":"10.1016\/j.ydbio.2019.11.011_bib44","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1016\/j.ydbio.2016.08.007","article-title":"Type 1 and 3 inositol trisphosphate receptors are required for extra-embryonic vascular development","volume":"418","author":"Uchida","year":"2016","journal-title":"Dev. Biol."},{"key":"10.1016\/j.ydbio.2019.11.011_bib45","doi-asserted-by":"crossref","first-page":"3731","DOI":"10.1242\/dev.096560","article-title":"Localized Fgf10 expression is not required for lung branching morphogenesis but prevents differentiation of epithelial progenitors","volume":"140","author":"Volckaert","year":"2013","journal-title":"Development"},{"key":"10.1016\/j.ydbio.2019.11.011_bib46","doi-asserted-by":"crossref","first-page":"3179","DOI":"10.1242\/dev.128.16.3179","article-title":"Conotruncal myocardium arises from a secondary heart field","volume":"128","author":"Waldo","year":"2001","journal-title":"Development"},{"key":"10.1016\/j.ydbio.2019.11.011_bib47","doi-asserted-by":"crossref","first-page":"3217","DOI":"10.1242\/dev.01174","article-title":"Tbx1 has a dual role in the morphogenesis of the cardiac outflow tract","volume":"131","author":"Xu","year":"2004","journal-title":"Dev. Dis."},{"key":"10.1016\/j.ydbio.2019.11.011_bib48","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1172\/JCI8856","article-title":"The basic helix-loop-helix transcription factor, dHAND, is required for vascular development","volume":"105","author":"Yamagishi","year":"2000","journal-title":"J.\u00a0Clin. Investig."},{"key":"10.1016\/j.ydbio.2019.11.011_bib49","doi-asserted-by":"crossref","first-page":"383","DOI":"10.1016\/S1471-4914(03)00141-2","article-title":"Unraveling the genetic and developmental mysteries of 22q11 deletion syndrome","volume":"9","author":"Yamagishi","year":"2003","journal-title":"Trends Mol. Med."},{"key":"10.1016\/j.ydbio.2019.11.011_bib50","doi-asserted-by":"crossref","first-page":"418","DOI":"10.3389\/fgene.2018.00418","article-title":"Fgf10 signaling in lung development, homeostasis, disease, and repair after injury","volume":"9","author":"Yuan","year":"2018","journal-title":"Front. Genet."},{"key":"10.1016\/j.ydbio.2019.11.011_bib51","doi-asserted-by":"crossref","first-page":"1019","DOI":"10.1016\/j.celrep.2017.01.002","article-title":"Temporally distinct six2-positive second heart field progenitors regulate mammalian heart development and disease","volume":"18","author":"Zhou","year":"2017","journal-title":"Cell Rep."}],"container-title":["Developmental Biology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0012160619304774?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0012160619304774?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,15]],"date-time":"2025-09-15T04:41:24Z","timestamp":1757911284000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0012160619304774"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,2]]},"references-count":51,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2020,2]]}},"alternative-id":["S0012160619304774"],"URL":"https:\/\/doi.org\/10.1016\/j.ydbio.2019.11.011","relation":{},"ISSN":["0012-1606"],"issn-type":[{"type":"print","value":"0012-1606"}],"subject":[],"published":{"date-parts":[[2020,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Inositol 1,4,5-trisphosphate receptor 2 as a novel marker of vasculature to delineate processes of cardiopulmonary development","name":"articletitle","label":"Article Title"},{"value":"Developmental Biology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ydbio.2019.11.011","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2019 Elsevier Inc.","name":"copyright","label":"Copyright"}]}}