{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,16]],"date-time":"2025-09-16T20:35:15Z","timestamp":1758054915660,"version":"3.44.0"},"reference-count":46,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2022,4,1]],"date-time":"2022-04-01T00:00:00Z","timestamp":1648771200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,4,1]],"date-time":"2022-04-01T00:00:00Z","timestamp":1648771200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2023,4,1]],"date-time":"2023-04-01T00:00:00Z","timestamp":1680307200000},"content-version":"vor","delay-in-days":365,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,4,1]],"date-time":"2022-04-01T00:00:00Z","timestamp":1648771200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2022,4,1]],"date-time":"2022-04-01T00:00:00Z","timestamp":1648771200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2022,4,1]],"date-time":"2022-04-01T00:00:00Z","timestamp":1648771200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2022,4,1]],"date-time":"2022-04-01T00:00:00Z","timestamp":1648771200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2022,4,1]],"date-time":"2022-04-01T00:00:00Z","timestamp":1648771200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Developmental Biology"],"published-print":{"date-parts":[[2022,4]]},"DOI":"10.1016\/j.ydbio.2022.02.002","type":"journal-article","created":{"date-parts":[[2022,2,5]],"date-time":"2022-02-05T10:13:44Z","timestamp":1644056024000},"page":"30-39","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":4,"special_numbering":"C","title":["Endoplasmic reticulum proteins Meigo and Gp93 govern dendrite targeting by regulating Toll-6 localization"],"prefix":"10.1016","volume":"484","author":[{"given":"Kosuke","family":"Kamemura","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hiroyuki","family":"Moriya","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yumiko","family":"Ukita","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Misako","family":"Okumura","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Masayuki","family":"Miura","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9989-3619","authenticated-orcid":false,"given":"Takahiro","family":"Chihara","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.ydbio.2022.02.002_bib1","doi-asserted-by":"crossref","first-page":"1054","DOI":"10.1101\/gad.297424.117","article-title":"Dendritic Eph organizes dendrodendritic segregation in discrete olfactory map formation in Drosophila","volume":"31","author":"Anzo","year":"2017","journal-title":"Genes Dev."},{"key":"10.1016\/j.ydbio.2022.02.002_bib2","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1101\/cshperspect.a015438","article-title":"Protein folding and quality control in the ER","volume":"4","author":"Araki","year":"2012","journal-title":"Cold Spring Harbor Perspect. Biol."},{"key":"10.1016\/j.ydbio.2022.02.002_bib3","doi-asserted-by":"crossref","first-page":"61","DOI":"10.3389\/fncel.2012.00061","article-title":"Molecular mechanisms of dendrite morphogenesis","volume":"6","author":"Arikkath","year":"2012","journal-title":"Front. Cell. Neurosci."},{"key":"10.1016\/j.ydbio.2022.02.002_bib4","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1146\/annurev-neuro-062012-170341","article-title":"Developmental mechanisms of topographic map formation and alignment","volume":"36","author":"Cang","year":"2013","journal-title":"Annu. Rev. Neurosci."},{"key":"10.1016\/j.ydbio.2022.02.002_bib5","doi-asserted-by":"crossref","first-page":"380","DOI":"10.1038\/s41583-019-0168-7","article-title":"Roles of axon guidance molecules in neuronal wiring in the developing spinal cord","volume":"20","author":"Ch\u00e9dotal","year":"2019","journal-title":"Nat. Rev. Neurosci."},{"key":"10.1016\/j.ydbio.2022.02.002_bib6","doi-asserted-by":"crossref","first-page":"156","DOI":"10.1186\/1471-2164-7-156","article-title":"Comparative genomics and evolution of the HSP90 family of genes across all kingdoms of organisms","volume":"7","author":"Chen","year":"2006","journal-title":"BMC Genom."},{"key":"10.1016\/j.ydbio.2022.02.002_bib7","doi-asserted-by":"crossref","first-page":"828","DOI":"10.1038\/nn1910","article-title":"Cytoplasmic and mitochondrial protein translation in axonal and dendritic terminal arborization","volume":"10","author":"Chihara","year":"2007","journal-title":"Nat. Neurosci."},{"key":"10.1016\/j.ydbio.2022.02.002_bib8","doi-asserted-by":"crossref","first-page":"325","DOI":"10.1038\/nsmb.2793","article-title":"Cleaning up in the endoplasmic reticulum: ubiquitin in charge","volume":"21","author":"Christianson","year":"2014","journal-title":"Nat. Struct. Mol. Biol."},{"key":"10.1016\/j.ydbio.2022.02.002_bib9","doi-asserted-by":"crossref","first-page":"791","DOI":"10.1016\/j.celrep.2013.09.046","article-title":"Xbp1-independent Ire1 signaling is required for photoreceptor differentiation and rhabdomere morphogenesis in Drosophila","volume":"5","author":"Coelho","year":"2013","journal-title":"Cell Rep."},{"key":"10.1016\/j.ydbio.2022.02.002_bib10","doi-asserted-by":"crossref","first-page":"479","DOI":"10.1016\/j.semcdb.2010.03.004","article-title":"GRP94 in ER quality control and stress responses","volume":"21","author":"Eletto","year":"2010","journal-title":"Semin. Cell Dev. Biol."},{"key":"10.1016\/j.ydbio.2022.02.002_bib11","doi-asserted-by":"crossref","first-page":"64","DOI":"10.1016\/j.neuron.2011.10.036","article-title":"Integrins regulate repulsion-mediated dendritic patterning of Drosophila sensory neurons by restricting dendrites in a 2D space","volume":"73","author":"Han","year":"2012","journal-title":"Neuron"},{"key":"10.1016\/j.ydbio.2022.02.002_bib12","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1038\/nature10926","article-title":"Teneurins instruct synaptic partner matching in an olfactory map","volume":"484","author":"Hong","year":"2012","journal-title":"Nature"},{"key":"10.1016\/j.ydbio.2022.02.002_bib13","doi-asserted-by":"crossref","first-page":"1542","DOI":"10.1038\/nn.2442","article-title":"Leucine-rich repeat transmembrane proteins instruct discrete dendrite targeting in an olfactory map","volume":"12","author":"Hong","year":"2009","journal-title":"Nat. Neurosci."},{"key":"10.1016\/j.ydbio.2022.02.002_bib14","doi-asserted-by":"crossref","first-page":"2337","DOI":"10.1242\/dev.004242","article-title":"Crk-associated substrate (Cas) signaling protein functions with integrins to specify axon guidance during development","volume":"134","author":"Huang","year":"2007","journal-title":"Development"},{"key":"10.1016\/j.ydbio.2022.02.002_bib15","doi-asserted-by":"crossref","first-page":"50","DOI":"10.1016\/j.semcdb.2005.12.002","article-title":"Wiring specificity in the olfactory system","volume":"17","author":"Jefferis","year":"2006","journal-title":"Semin. Cell Dev. Biol."},{"key":"10.1016\/j.ydbio.2022.02.002_bib16","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1242\/dev.00896","article-title":"Developmental origin of wiring specificity in the olfactory system of Drosophila","volume":"131","author":"Jefferis","year":"2004","journal-title":"Development"},{"key":"10.1016\/j.ydbio.2022.02.002_bib17","doi-asserted-by":"crossref","first-page":"230","DOI":"10.1111\/gtc.12835","article-title":"Amyotrophic lateral sclerosis-associated Vap33 is required for maintaining neuronal dendrite morphology and organelle distribution in Drosophila","volume":"26","author":"Kamemura","year":"2021","journal-title":"Gene Cell."},{"key":"10.1016\/j.ydbio.2022.02.002_bib18","doi-asserted-by":"crossref","first-page":"1294","DOI":"10.1038\/nn1763","article-title":"NGL family PSD-95-interacting adhesion molecules regulate excitatory synapse formation","volume":"9","author":"Kim","year":"2006","journal-title":"Nat. Neurosci."},{"key":"10.1016\/j.ydbio.2022.02.002_bib19","doi-asserted-by":"crossref","first-page":"3489","DOI":"10.1038\/s41467-018-06003-9","article-title":"AXER is an ATP\/ADP exchanger in the membrane of the endoplasmic reticulum","volume":"9","author":"Klein","year":"2018","journal-title":"Nat. Commun."},{"key":"10.1016\/j.ydbio.2022.02.002_bib20","doi-asserted-by":"crossref","first-page":"399","DOI":"10.1016\/j.cell.2006.12.028","article-title":"Graded expression of Semaphorin-1a cell-autonomously directs dendritic targeting of olfactory projection neurons","volume":"128","author":"Komiyama","year":"2007","journal-title":"Cell"},{"key":"10.1016\/j.ydbio.2022.02.002_bib21","doi-asserted-by":"crossref","first-page":"462","DOI":"10.1038\/332462a0","article-title":"The presence of malfolded proteins in the endoplasmic reticulum signals the induction of glucose-regulated proteins","volume":"332","author":"Kozutsumi","year":"1988","journal-title":"Nature"},{"key":"10.1016\/j.ydbio.2022.02.002_bib22","doi-asserted-by":"crossref","first-page":"1223","DOI":"10.1182\/blood-2008-03-143107","article-title":"Endoplasmic reticulum HSP90bl (gp96, grp94) optimizes B-cell function via chaperoning integrin and TLR but not immunoglobulin","volume":"112","author":"Liu","year":"2008","journal-title":"Blood"},{"key":"10.1016\/j.ydbio.2022.02.002_bib23","first-page":"2583","article-title":"A\u00a0protocol for mosaic analysis with a repressible cell marker (MARCM) in Drosophila","volume":"1","author":"Luo","year":"2007","journal-title":"Nat. Protoc."},{"key":"10.1016\/j.ydbio.2022.02.002_bib24","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1016\/j.ydbio.2009.12.023","article-title":"Gp93, the Drosophila GRP94 ortholog, is required for gut epithelial homeostasis and nutrient assimilation-coupled growth control","volume":"339","author":"Maynard","year":"2010","journal-title":"Dev. Biol."},{"key":"10.1016\/j.ydbio.2022.02.002_bib25","first-page":"5121","article-title":"Substrate (Cas) signaling protein functions with integrins to specify axon guidance during development. pd. Space.pdfShuang I.R.R.D.P. of D.S.N. by R.D. in a T., Yang, Y., Hao, B., Li, Z","volume":"183","author":"Morales","year":"2009","journal-title":"Drosophila Glycoprotein 93 Is an Ortholog of Mammalian Heat Shock Protein gp96 (grp94, HSP90b1, HSPC4) and Retains Disulfide Bond-Independent Chaperone Function for TLRs and Integrins. J. Immunol."},{"key":"10.1016\/j.ydbio.2022.02.002_bib26","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1093\/jb\/mvx047","article-title":"Role of the unfolded protein response in the development of central nervous system","volume":"162","author":"Murao","year":"2017","journal-title":"J.\u00a0Biochem."},{"key":"10.1016\/j.ydbio.2022.02.002_bib27","doi-asserted-by":"crossref","first-page":"1033","DOI":"10.1016\/S0092-8674(00)00207-5","article-title":"Selecting a longitudinal pathway: Robo receptors specify the lateral position of axons in the Drosophila CNS","volume":"103","author":"Rajagopalan","year":"2000","journal-title":"Cell"},{"key":"10.1016\/j.ydbio.2022.02.002_bib28","doi-asserted-by":"crossref","first-page":"891","DOI":"10.1038\/ncb1001-891","article-title":"Endoplasmic reticulum chaperone gp96 is required for innate immunity but not cell viability","volume":"3","author":"Randow","year":"2001","journal-title":"Nat. Cell Biol."},{"key":"10.1016\/j.ydbio.2022.02.002_bib29","doi-asserted-by":"crossref","first-page":"423","DOI":"10.1111\/j.1365-313X.2009.04066.x","article-title":"The nucleotide sugar transporters AtUTr1 and AtUTr3 are required for the incorporation of UDP-glucose into the endoplasmic reticulum, are essential for pollen development and are needed for embryo sac progress in Arabidopsis thaliana","volume":"61","author":"Reyes","year":"2010","journal-title":"Plant J."},{"key":"10.1016\/j.ydbio.2022.02.002_bib30","doi-asserted-by":"crossref","first-page":"873","DOI":"10.1083\/jcb.200202032","article-title":"Drosophila EB1 is important for proper assembly, dynamics, and positioning of the mitotic spindle","volume":"158","author":"Rogers","year":"2002","journal-title":"J.\u00a0Cell Biol."},{"key":"10.1016\/j.ydbio.2022.02.002_bib31","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1266\/ggs.89.17","article-title":"Development of olfactory projection neuron dendrites that contribute to wiring specificity of the Drosophila olfactory circuit","volume":"89","author":"Sakuma","year":"2014","journal-title":"Genes Genet. Syst."},{"key":"10.1016\/j.ydbio.2022.02.002_bib32","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1016\/j.mrfmmm.2004.06.056","article-title":"ER stress and the unfolded protein response","volume":"569","author":"Schr\u00f6der","year":"2005","journal-title":"Mutat. Res."},{"key":"10.1016\/j.ydbio.2022.02.002_bib33","doi-asserted-by":"crossref","first-page":"683","DOI":"10.1038\/nn.3389","article-title":"Meigo governs dendrite targeting specificity by modulating Ephrin level and N -glycosylation","volume":"16","author":"Sekine","year":"2013","journal-title":"Nat. Neurosci."},{"key":"10.1016\/j.ydbio.2022.02.002_bib34","doi-asserted-by":"crossref","first-page":"2118","DOI":"10.1126\/science.280.5372.2118","article-title":"Drosophila synapse formation: regulation by transmembrane protein with leu-rich repeats, Capricious","volume":"280","author":"Shishido","year":"1998","journal-title":"Science"},{"key":"10.1016\/j.ydbio.2022.02.002_bib35","doi-asserted-by":"crossref","first-page":"1019","DOI":"10.1016\/S0092-8674(00)00206-3","article-title":"Short-range and long-range guidance by Slit and its Robo receptors: a combinatorial code of Robo receptors controls lateral position 103","volume":"103","author":"Simpson","year":"2000","journal-title":"Cell"},{"key":"10.1016\/j.ydbio.2022.02.002_bib36","doi-asserted-by":"crossref","first-page":"364","DOI":"10.1111\/j.1550-7408.2004.tb00580.x","article-title":"Evolutionary origins of Hsp90 chaperones and a deep paralog in their bacterial ancestors","volume":"51","author":"Stechmann","year":"2004","journal-title":"J.\u00a0Eukaryot. Microbiol."},{"key":"10.1016\/j.ydbio.2022.02.002_bib37","doi-asserted-by":"crossref","DOI":"10.1242\/dev.151415","article-title":"Understanding axon guidance: are we nearly there yet?","volume":"145","author":"Stoeckli","year":"2018","journal-title":"Development"},{"key":"10.1016\/j.ydbio.2022.02.002_bib38","doi-asserted-by":"crossref","first-page":"944","DOI":"10.1038\/nrm2546","article-title":"One step at a time: endoplasmic reticulum-associated degradation","volume":"9","author":"Vembar","year":"2008","journal-title":"Nat. Rev. Mol. Cell Biol."},{"key":"10.1016\/j.ydbio.2022.02.002_bib39","doi-asserted-by":"crossref","first-page":"1013","DOI":"10.1016\/j.neuron.2015.02.003","article-title":"Toll receptors instruct axon and dendrite targeting and participate in synaptic partner matching in a Drosophila olfactory circuit","volume":"85","author":"Ward","year":"2015","journal-title":"Neuron"},{"key":"10.1016\/j.ydbio.2022.02.002_bib40","doi-asserted-by":"crossref","DOI":"10.7554\/eLife.06963","article-title":"The unfolded protein response is required for dendrite morphogenesis","volume":"4","author":"Wei","year":"2015","journal-title":"Elife"},{"key":"10.1016\/j.ydbio.2022.02.002_bib41","doi-asserted-by":"crossref","first-page":"771","DOI":"10.1111\/j.1440-169X.2010.01213.x","article-title":"Functional analysis of Toll-related genes in Drosophila","volume":"52","author":"Yagi","year":"2010","journal-title":"Dev. Growth Differ."},{"key":"10.1016\/j.ydbio.2022.02.002_bib42","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1016\/S1016-8478(23)13214-6","article-title":"Roles of heat shock protein gp96 in the ER quality control: redundant or unique function?","volume":"20","author":"Yang","year":"2005","journal-title":"Mol. Cell"},{"key":"10.1016\/j.ydbio.2022.02.002_bib43","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1016\/j.immuni.2006.12.005","article-title":"Heat shock protein gp96 is a master chaperone for toll-like receptors and is important in the innate function of macrophages","volume":"26","author":"Yang","year":"2007","journal-title":"Immunity"},{"key":"10.1016\/j.ydbio.2022.02.002_bib44","doi-asserted-by":"crossref","first-page":"71","DOI":"10.3389\/fnmol.2012.00071","article-title":"Semaphorin signaling in vertebrate neural circuit assembly","volume":"5","author":"Yoshida","year":"2012","journal-title":"Front. Mol. Neurosci."},{"key":"10.1016\/j.ydbio.2022.02.002_bib45","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1038\/nn1652","article-title":"Dendritic patterning by Dscam and synaptic partner matching in the Drosophila antennal lobe","volume":"9","author":"Zhu","year":"2006","journal-title":"Nat. Neurosci."},{"key":"10.1016\/j.ydbio.2022.02.002_bib46","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1016\/S0896-6273(04)00142-4","article-title":"Diverse functions of N-cadherin in dendritic and axonal terminal arborization of olfactory projection Neurons 42, 63\u201375","volume":"42","author":"Zhu","year":"2004","journal-title":"Neuron"}],"container-title":["Developmental Biology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0012160622000161?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0012160622000161?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,15]],"date-time":"2025-09-15T05:57:07Z","timestamp":1757915827000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0012160622000161"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,4]]},"references-count":46,"alternative-id":["S0012160622000161"],"URL":"https:\/\/doi.org\/10.1016\/j.ydbio.2022.02.002","relation":{},"ISSN":["0012-1606"],"issn-type":[{"type":"print","value":"0012-1606"}],"subject":[],"published":{"date-parts":[[2022,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Endoplasmic reticulum proteins Meigo and Gp93 govern dendrite targeting by regulating Toll-6 localization","name":"articletitle","label":"Article Title"},{"value":"Developmental Biology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ydbio.2022.02.002","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2022 Elsevier Inc.","name":"copyright","label":"Copyright"}]}}