{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T01:37:09Z","timestamp":1777513029298,"version":"3.51.4"},"reference-count":63,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2023,4,1]],"date-time":"2023-04-01T00:00:00Z","timestamp":1680307200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,4,1]],"date-time":"2023-04-01T00:00:00Z","timestamp":1680307200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,4,1]],"date-time":"2024-04-01T00:00:00Z","timestamp":1711929600000},"content-version":"vor","delay-in-days":366,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,4,1]],"date-time":"2023-04-01T00:00:00Z","timestamp":1680307200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2023,4,1]],"date-time":"2023-04-01T00:00:00Z","timestamp":1680307200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2023,4,1]],"date-time":"2023-04-01T00:00:00Z","timestamp":1680307200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2023,4,1]],"date-time":"2023-04-01T00:00:00Z","timestamp":1680307200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2023,4,1]],"date-time":"2023-04-01T00:00:00Z","timestamp":1680307200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100007129","name":"Natural Science Foundation of Shandong Province","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100007129","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81974333"],"award-info":[{"award-number":["81974333"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82172414"],"award-info":[{"award-number":["82172414"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["ZR2022QH252"],"award-info":[{"award-number":["ZR2022QH252"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004912","name":"Sichuan University","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004912","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Developmental Biology"],"published-print":{"date-parts":[[2023,4]]},"DOI":"10.1016\/j.ydbio.2023.02.004","type":"journal-article","created":{"date-parts":[[2023,2,19]],"date-time":"2023-02-19T20:23:00Z","timestamp":1676838180000},"page":"73-86","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":6,"special_numbering":"C","title":["Connexin43 overexpression promotes bone regeneration by osteogenesis and angiogenesis in rat glucocorticoid-induced osteonecrosis of the femoral head"],"prefix":"10.1016","volume":"496","author":[{"given":"Xin","family":"Zhao","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Changjun","family":"Chen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yue","family":"Luo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Donghai","family":"Li","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Qiuru","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yuying","family":"Fang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pengde","family":"Kang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"23","key":"10.1016\/j.ydbio.2023.02.004_bib1","doi-asserted-by":"crossref","first-page":"4429","DOI":"10.1038\/s41388-019-0741-6","article-title":"Connexins in cancer: bridging the gap to the clinic","volume":"38","author":"Aasen","year":"2019","journal-title":"Oncogene"},{"key":"10.1016\/j.ydbio.2023.02.004_bib2","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1016\/j.brainres.2012.08.042","article-title":"Connexin and pannexin hemichannels in inflammatory responses of glia and neurons","volume":"1487","author":"Bennett","year":"2012","journal-title":"Brain Res."},{"issue":"10","key":"10.1016\/j.ydbio.2023.02.004_bib3","doi-asserted-by":"crossref","first-page":"1107","DOI":"10.1002\/sctm.18-0218","article-title":"Gene modification and three-dimensional scaffolds as novel tools to allow the use of postnatal thymic epithelial cells for thymus regeneration approaches","volume":"8","author":"Bortolomai","year":"2019","journal-title":"Stem Cells Transl Med"},{"key":"10.1016\/j.ydbio.2023.02.004_bib4","doi-asserted-by":"crossref","first-page":"210","DOI":"10.1186\/s13287-015-0200-4","article-title":"Aspirin promotes bone marrow mesenchymal stem cell-based calvarial bone regeneration in mini swine","volume":"6","author":"Cao","year":"2015","journal-title":"Stem Cell Res. Ther."},{"key":"10.1016\/j.ydbio.2023.02.004_bib5","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1016\/j.actbio.2020.02.031","article-title":"Scaffold-Free tissue engineering with aligned bone marrow stromal cell sheets to recapitulate the microstructural and biochemical composition of annulus fibrosus","volume":"107","author":"Chuah","year":"2020","journal-title":"Acta Biomater."},{"issue":"1","key":"10.1016\/j.ydbio.2023.02.004_bib6","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1016\/j.mce.2010.04.005","article-title":"The anti-inflammatory and immunosuppressive effects of glucocorticoids, recent developments and mechanistic insights","volume":"335","author":"Coutinho","year":"2011","journal-title":"Mol. Cell. Endocrinol."},{"issue":"3","key":"10.1016\/j.ydbio.2023.02.004_bib7","doi-asserted-by":"crossref","first-page":"377","DOI":"10.18388\/abp.2017_1592","article-title":"Connexin-dependent intercellular stress signaling in tissue homeostasis and tumor development","volume":"64","author":"Czy\u017c","year":"2017","journal-title":"Acta Biochim. Pol."},{"issue":"1","key":"10.1016\/j.ydbio.2023.02.004_bib8","doi-asserted-by":"crossref","first-page":"226","DOI":"10.1186\/s13018-019-1279-6","article-title":"Impairment of circulating endothelial progenitor cells (EPCs) in patients with glucocorticoid-induced avascular necrosis of the femoral head and changes of EPCs after glucocorticoid treatment in vitro","volume":"14","author":"Ding","year":"2019","journal-title":"J.\u00a0Orthop. Surg. Res."},{"key":"10.1016\/j.ydbio.2023.02.004_bib9","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1186\/s12891-015-0511-8","article-title":"Mesenchymal stem cells in rabbit meniscus and bone marrow exhibit a similar feature but a heterogeneous multi-differentiation potential: superiority of meniscus as a cell source for meniscus repair","volume":"16","author":"Ding","year":"2015","journal-title":"BMC Muscoskel. Disord."},{"key":"10.1016\/j.ydbio.2023.02.004_bib10","doi-asserted-by":"crossref","DOI":"10.1089\/scd.2020.0019","article-title":"Longtime outcome after intraosseous application of autologous mesenchymal stromal cells in pediatric patients and young adults with avascular necrosis after steroid or chemotherapy","author":"D\u00f6ring","year":"2020","journal-title":"Stem Cell. Dev."},{"issue":"13","key":"10.1016\/j.ydbio.2023.02.004_bib11","doi-asserted-by":"crossref","DOI":"10.1242\/jcs.216135","article-title":"The effect of gap junction-mediated transfer of miR-200b on osteogenesis and angiogenesis in a co-culture of MSCs and HUVECs","volume":"131","author":"Fan","year":"2018","journal-title":"J.\u00a0Cell Sci."},{"issue":"5","key":"10.1016\/j.ydbio.2023.02.004_bib12","doi-asserted-by":"crossref","first-page":"1005","DOI":"10.1016\/j.bone.2011.07.032","article-title":"Autologous bone marrow cell implantation in the treatment of non-traumatic osteonecrosis of the femoral head: five year follow-up of a prospective controlled study","volume":"49","author":"Gangji","year":"2011","journal-title":"Bone"},{"key":"10.1016\/j.ydbio.2023.02.004_bib13","article-title":"Harnessing stem cell potential for the treatment of erectile function with diabetes mellitus: from preclinical\/clinical perspectives to penile tissue engineering","author":"Gur","year":"2019","journal-title":"Curr. Stem Cell Res. Ther."},{"issue":"16","key":"10.1016\/j.ydbio.2023.02.004_bib14","doi-asserted-by":"crossref","first-page":"1603","DOI":"10.2174\/1389450120666190726155733","article-title":"Recent progress in gene therapy and other targeted therapeutic approaches for beta thalassemia","volume":"20","author":"Hamed","year":"2019","journal-title":"Curr. Drug Targets"},{"issue":"1","key":"10.1016\/j.ydbio.2023.02.004_bib15","doi-asserted-by":"crossref","first-page":"377","DOI":"10.1186\/s13287-019-1498-0","article-title":"The shift in the balance between osteoblastogenesis and adipogenesis of mesenchymal stem cells mediated by glucocorticoid receptor","volume":"10","author":"Han","year":"2019","journal-title":"Stem Cell Res. Ther."},{"issue":"11","key":"10.1016\/j.ydbio.2023.02.004_bib16","doi-asserted-by":"crossref","first-page":"2173","DOI":"10.1111\/jcmm.12917","article-title":"P-glycoprotein overexpression in bone marrow-derived multipotent stromal cells decreases the risk of steroid-induced osteonecrosis in the femoral head","volume":"20","author":"Han","year":"2016","journal-title":"J.\u00a0Cell Mol. Med."},{"issue":"6","key":"10.1016\/j.ydbio.2023.02.004_bib17","doi-asserted-by":"crossref","first-page":"495","DOI":"10.1159\/000329502","article-title":"Treatment of osteonecrosis of the femoral head with VEGF165 transgenic bone marrow mesenchymal stem cells in mongrel dogs","volume":"195","author":"Hang","year":"2012","journal-title":"Cells Tissues Organs"},{"key":"10.1016\/j.ydbio.2023.02.004_bib18","doi-asserted-by":"crossref","first-page":"106","DOI":"10.1016\/j.reth.2019.06.002","article-title":"Transplantation of autologous bone marrow-derived mesenchymal stem cells under arthroscopic surgery with microfracture versus microfracture alone for articular cartilage lesions in the knee: a multicenter prospective randomized control clinical trial","volume":"11","author":"Hashimoto","year":"2019","journal-title":"Regen Ther"},{"issue":"12","key":"10.1016\/j.ydbio.2023.02.004_bib19","doi-asserted-by":"crossref","first-page":"2949","DOI":"10.1007\/s00264-017-3716-7","article-title":"Stem cell therapy in early post-traumatic talus osteonecrosis","volume":"42","author":"Hernigou","year":"2018","journal-title":"Int. Orthop."},{"issue":"1","key":"10.1016\/j.ydbio.2023.02.004_bib20","doi-asserted-by":"crossref","first-page":"1","DOI":"10.4055\/cios.2016.8.1.1","article-title":"Stem cell therapy for the treatment of hip osteonecrosis: a 30-year review of progress","volume":"8","author":"Hernigou","year":"2016","journal-title":"Clin. Orthop. Surg."},{"issue":"1","key":"10.1016\/j.ydbio.2023.02.004_bib21","doi-asserted-by":"crossref","first-page":"169","DOI":"10.7150\/thno.21234","article-title":"Exosomes from human umbilical cord blood accelerate cutaneous wound healing through miR-21-3p-mediated promotion of angiogenesis and fibroblast function","volume":"8","author":"Hu","year":"2018","journal-title":"Theranostics"},{"key":"10.1016\/j.ydbio.2023.02.004_bib22","doi-asserted-by":"crossref","DOI":"10.1016\/j.jsbmb.2019.04.012","article-title":"IGF-1 reverses the osteogenic inhibitory effect of dexamethasone on BMP9-induced osteogenic differentiation in mouse embryonic fibroblasts via PI3K\/AKT\/COX-2 pathway","volume":"191","author":"Jiang","year":"2019","journal-title":"J.\u00a0Steroid Biochem. Mol. Biol."},{"key":"10.1016\/j.ydbio.2023.02.004_bib23","doi-asserted-by":"crossref","first-page":"1450","DOI":"10.2741\/2159","article-title":"Roles of gap junctions and hemichannels in bone cell functions and in signal transmission of mechanical stress","volume":"12","author":"Jiang","year":"2007","journal-title":"Front. Biosci."},{"issue":"2","key":"10.1016\/j.ydbio.2023.02.004_bib24","doi-asserted-by":"crossref","first-page":"510","DOI":"10.3349\/ymj.2013.54.2.510","article-title":"Clinical results of auto-iliac cancellous bone grafts combined with implantation of autologous bone marrow cells for osteonecrosis of the femoral head: a minimum 5-year follow-up","volume":"54","author":"Kang","year":"2013","journal-title":"Yonsei Med. J."},{"issue":"1","key":"10.1016\/j.ydbio.2023.02.004_bib25","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1016\/j.abb.2012.03.008","article-title":"Biological role of connexin intercellular channels and hemichannels","volume":"524","author":"Kar","year":"2012","journal-title":"Arch. Biochem. Biophys."},{"issue":"4","key":"10.1016\/j.ydbio.2023.02.004_bib26","doi-asserted-by":"crossref","DOI":"10.1172\/jci.insight.126268","article-title":"Genetic modification increases the survival and the neuroregenerative properties of transplanted neural stem cells","volume":"5","author":"Korshunova","year":"2020","journal-title":"JCI Insight"},{"issue":"4","key":"10.1016\/j.ydbio.2023.02.004_bib27","doi-asserted-by":"crossref","first-page":"407","DOI":"10.1016\/j.jos.2016.03.008","article-title":"Clinical and basic research on steroid-induced osteonecrosis of the femoral head in Japan","volume":"21","author":"Kubo","year":"2016","journal-title":"J.\u00a0Orthop. Sci."},{"issue":"3","key":"10.1016\/j.ydbio.2023.02.004_bib28","doi-asserted-by":"crossref","first-page":"438","DOI":"10.1111\/bjh.16205","article-title":"Pre- and post-serial metagenomic analysis of gut microbiota as a prognostic factor in patients undergoing haematopoietic stem cell transplantation","volume":"188","author":"Kusakabe","year":"2020","journal-title":"Br. J. Haematol."},{"issue":"1","key":"10.1016\/j.ydbio.2023.02.004_bib29","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1016\/j.bbamem.2017.05.008","article-title":"The connexin 43 C-terminus: a tail of many tales","volume":"1860","author":"Leithe","year":"2018","journal-title":"Biochim. Biophys. Acta Biomembr."},{"issue":"1","key":"10.1016\/j.ydbio.2023.02.004_bib30","first-page":"128","article-title":"Efficacy of autologous bone marrow mesenchymal stem cells in the treatment of knee osteoarthritis and their effects on the expression of serum TNF-\u03b1 and IL-6","volume":"20","author":"Li","year":"2020","journal-title":"J.\u00a0Musculoskelet. Neuronal Interact."},{"issue":"7","key":"10.1016\/j.ydbio.2023.02.004_bib31","doi-asserted-by":"crossref","first-page":"1008","DOI":"10.1002\/jor.22830","article-title":"Connexin 43 and ERK regulate tension-induced signal transduction in human periodontal ligament fibroblasts","volume":"33","author":"Li","year":"2015","journal-title":"J.\u00a0Orthop. Res."},{"issue":"1","key":"10.1016\/j.ydbio.2023.02.004_bib32","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1159\/000489763","article-title":"Connexin 43 modulates osteogenic differentiation of bone marrow stromal cells through GSK-3beta\/beta-catenin signaling pathways","volume":"47","author":"Lin","year":"2018","journal-title":"Cell. Physiol. Biochem."},{"key":"10.1016\/j.ydbio.2023.02.004_bib33","doi-asserted-by":"crossref","first-page":"354","DOI":"10.1016\/j.intimp.2019.03.002","article-title":"Risk of infection with different immunosuppressive drugs combined with glucocorticoids for the treatment of idiopathic membranous nephropathy: a pairwise and network meta-analysis","volume":"70","author":"Liu","year":"2019","journal-title":"Int. Immunopharm."},{"issue":"9","key":"10.1016\/j.ydbio.2023.02.004_bib34","doi-asserted-by":"crossref","first-page":"1681","DOI":"10.1007\/s00018-019-03019-2","article-title":"Therapeutic potential of menstrual blood-derived endometrial stem cells in cardiac diseases","volume":"76","author":"Liu","year":"2019","journal-title":"Cell. Mol. Life Sci."},{"issue":"1","key":"10.1016\/j.ydbio.2023.02.004_bib35","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1007\/s11914-017-0345-4","article-title":"Connexin43 and the intercellular signaling network regulating skeletal remodeling","volume":"15","author":"Moorer","year":"2017","journal-title":"Curr. Osteoporos. Rep."},{"issue":"12","key":"10.1016\/j.ydbio.2023.02.004_bib36","doi-asserted-by":"crossref","first-page":"3381","DOI":"10.1074\/mcp.M114.040691","article-title":"O-GlcNAc modification of the runt-related transcription factor 2 (Runx2) links osteogenesis and nutrient metabolism in bone marrow mesenchymal stem cells","volume":"13","author":"Nagel","year":"2014","journal-title":"Mol. Cell. Proteomics"},{"issue":"3","key":"10.1016\/j.ydbio.2023.02.004_bib37","doi-asserted-by":"crossref","DOI":"10.3390\/cells9030757","article-title":"Effect of chemically induced hypoxia on osteogenic and angiogenic differentiation of bone marrow mesenchymal stem cells and human umbilical vein endothelial cells in Direct coculture","volume":"9","author":"Nguyen","year":"2020","journal-title":"Cells"},{"issue":"1","key":"10.1016\/j.ydbio.2023.02.004_bib38","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1186\/s13287-020-01595-w","article-title":"Prognosis after autologous peripheral blood stem cell transplantation for osteonecrosis of the femoral head in the pre-collapse stage: a retrospective cohort study","volume":"11","author":"Pan","year":"2020","journal-title":"Stem Cell Res. Ther."},{"issue":"4","key":"10.1016\/j.ydbio.2023.02.004_bib39","doi-asserted-by":"crossref","first-page":"1648","DOI":"10.1159\/000484026","article-title":"Adenovirus-Mediated expression of BMP-2 and BFGF in bone marrow mesenchymal stem cells combined with demineralized bone matrix for repair of femoral head osteonecrosis in beagle dogs","volume":"43","author":"Peng","year":"2017","journal-title":"Cell. Physiol. Biochem."},{"issue":"Suppl. 1","key":"10.1016\/j.ydbio.2023.02.004_bib40","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1186\/s12860-016-0088-6","article-title":"Role of connexins and pannexins during ontogeny, regeneration, and pathologies of bone","volume":"17","author":"Plotkin","year":"2016","journal-title":"BMC Cell Biol."},{"issue":"2","key":"10.1016\/j.ydbio.2023.02.004_bib41","doi-asserted-by":"crossref","first-page":"525","DOI":"10.1152\/physrev.00010.2019","article-title":"Connexins: key players in the control of vascular plasticity and function","volume":"100","author":"Pohl","year":"2020","journal-title":"Physiol. Rev."},{"issue":"4","key":"10.1016\/j.ydbio.2023.02.004_bib42","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1080\/10495398.2017.1279169","article-title":"Use of pig as a model for mesenchymal stem cell therapies for bone regeneration","volume":"28","author":"Rubessa","year":"2017","journal-title":"Anim. Biotechnol."},{"issue":"4","key":"10.1016\/j.ydbio.2023.02.004_bib43","doi-asserted-by":"crossref","first-page":"801","DOI":"10.1002\/jbmr.3947","article-title":"Involvement of the gut microbiota and barrier function in glucocorticoid-induced osteoporosis","volume":"35","author":"Schepper","year":"2020","journal-title":"J.\u00a0Bone Miner. Res."},{"issue":"1","key":"10.1016\/j.ydbio.2023.02.004_bib44","doi-asserted-by":"crossref","first-page":"88","DOI":"10.1007\/s00223-016-0121-y","article-title":"Glucocorticoid suppresses connexin 43 expression by inhibiting the akt\/mTOR signaling pathway in osteoblasts","volume":"99","author":"Shen","year":"2016","journal-title":"Calcif. Tissue Int."},{"issue":"1","key":"10.1016\/j.ydbio.2023.02.004_bib45","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1186\/s12916-016-0673-8","article-title":"Risk of serious infections with immunosuppressive drugs and glucocorticoids for lupus nephritis: a systematic review and network meta-analysis","volume":"14","author":"Singh","year":"2016","journal-title":"BMC Med."},{"issue":"26","key":"10.1016\/j.ydbio.2023.02.004_bib46","doi-asserted-by":"crossref","first-page":"E5934","DOI":"10.1073\/pnas.1803907115","article-title":"Suppression of connexin 43 phosphorylation promotes astrocyte survival and vascular regeneration in proliferative retinopathy","volume":"115","author":"Slavi","year":"2018","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"10.1016\/j.ydbio.2023.02.004_bib47","doi-asserted-by":"crossref","DOI":"10.1038\/s41435-020-0096-6","article-title":"Extra-adrenal glucocorticoid biosynthesis: implications for autoimmune and inflammatory disorders","author":"Slominski","year":"2020","journal-title":"Gene Immun."},{"issue":"3","key":"10.1016\/j.ydbio.2023.02.004_bib48","doi-asserted-by":"crossref","first-page":"733","DOI":"10.7150\/thno.17450","article-title":"Exosomes derived from human platelet-rich plasma prevent apoptosis induced by glucocorticoid-associated endoplasmic reticulum stress in rat osteonecrosis of the femoral head via the Akt\/Bad\/Bcl-2 signal pathway","volume":"7","author":"Tao","year":"2017","journal-title":"Theranostics"},{"issue":"4","key":"10.1016\/j.ydbio.2023.02.004_bib49","doi-asserted-by":"crossref","first-page":"1095","DOI":"10.3892\/mmr.2014.1923","article-title":"Cx43 in mesenchymal stem cells promotes angiogenesis of the infarcted heart independent of gap junctions","volume":"9","author":"Wang","year":"2014","journal-title":"Mol. Med. Rep."},{"issue":"3","key":"10.1016\/j.ydbio.2023.02.004_bib50","doi-asserted-by":"crossref","first-page":"553","DOI":"10.1007\/s10456-013-9335-z","article-title":"Reduction of connexin43 in human endothelial progenitor cells impairs the angiogenic potential","volume":"16","author":"Wang","year":"2013","journal-title":"Angiogenesis"},{"issue":"9","key":"10.1016\/j.ydbio.2023.02.004_bib51","doi-asserted-by":"crossref","first-page":"2200","DOI":"10.1177\/0363546519854219","article-title":"Chondrogenic progenitor cells exhibit superiority over mesenchymal stem cells and chondrocytes in platelet-rich plasma scaffold-based cartilage regeneration","volume":"47","author":"Wang","year":"2019","journal-title":"Am. J. Sports Med."},{"issue":"1","key":"10.1016\/j.ydbio.2023.02.004_bib52","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1186\/s12891-020-3064-4","article-title":"Correlation between the efficacy of stem cell therapy for osteonecrosis of the femoral head and cell viability","volume":"21","author":"Wu","year":"2020","journal-title":"BMC Muscoskel. Disord."},{"key":"10.1016\/j.ydbio.2023.02.004_bib53","article-title":"Dexamethasone interferes with osteoblasts formation during osteogenesis through altering IGF-1-mediated angiogenesis","author":"Xu","year":"2019","journal-title":"J.\u00a0Cell. Physiol."},{"issue":"6","key":"10.1016\/j.ydbio.2023.02.004_bib54","doi-asserted-by":"crossref","first-page":"2561","DOI":"10.1159\/000489684","article-title":"Stromal-cell-derived factor (SDF) 1-alpha overexpression promotes bone regeneration by osteogenesis and angiogenesis in osteonecrosis of the femoral head","volume":"46","author":"Yang","year":"2018","journal-title":"Cell. Physiol. Biochem."},{"issue":"1","key":"10.1016\/j.ydbio.2023.02.004_bib55","doi-asserted-by":"crossref","first-page":"277","DOI":"10.1186\/s12891-020-03225-1","article-title":"Decreased angiogenic and increased apoptotic activities of bone microvascular endothelial cells in patients with glucocorticoid-induced osteonecrosis of the femoral head","volume":"21","author":"Yu","year":"2020","journal-title":"BMC Muscoskel. Disord."},{"issue":"1","key":"10.1016\/j.ydbio.2023.02.004_bib56","doi-asserted-by":"crossref","first-page":"417","DOI":"10.1002\/jor.23613","article-title":"Regulatory effect of microRNA-34a on osteogenesis and angiogenesis in glucocorticoid-induced osteonecrosis of the femoral head","volume":"36","author":"Zha","year":"2018","journal-title":"J.\u00a0Orthop. Res."},{"issue":"1","key":"10.1016\/j.ydbio.2023.02.004_bib57","doi-asserted-by":"crossref","first-page":"325","DOI":"10.1016\/j.bone.2011.11.002","article-title":"Treatment of early stage osteonecrosis of the femoral head with autologous implantation of bone marrow-derived and cultured mesenchymal stem cells","volume":"50","author":"Zhao","year":"2012","journal-title":"Bone"},{"issue":"10","key":"10.1016\/j.ydbio.2023.02.004_bib58","doi-asserted-by":"crossref","first-page":"1099","DOI":"10.2174\/1381612825666190527092948","article-title":"A\u00a0mini review: stem cell therapy for osteonecrosis of the femoral head and pharmacological aspects","volume":"25","author":"Zhao","year":"2019","journal-title":"Curr. Pharmaceut. Des."},{"issue":"2","key":"10.1016\/j.ydbio.2023.02.004_bib59","doi-asserted-by":"crossref","first-page":"725","DOI":"10.1089\/ten.tea.2009.0495","article-title":"Transforming growth factor beta1 induces osteogenic differentiation of murine bone marrow stromal cells","volume":"16","author":"Zhao","year":"2010","journal-title":"Tissue Eng."},{"key":"10.1016\/j.ydbio.2023.02.004_bib60","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.neuroscience.2017.08.027","article-title":"Expression of Ski and its role in astrocyte proliferation and migration","volume":"362","author":"Zhao","year":"2017","journal-title":"Neuroscience"},{"issue":"5","key":"10.1016\/j.ydbio.2023.02.004_bib61","doi-asserted-by":"crossref","first-page":"506","DOI":"10.1007\/s00223-019-00592-3","article-title":"Glucocorticoid enhanced the expression of ski in osteonecrosis of femoral head: the effect on adipogenesis of rabbit BMSCs","volume":"105","author":"Zhao","year":"2019","journal-title":"Calcif. Tissue Int."},{"issue":"6","key":"10.1016\/j.ydbio.2023.02.004_bib62","first-page":"3433","article-title":"Valproic acid prevents glucocorticoid-induced osteonecrosis of the femoral head of rats","volume":"41","author":"Zhou","year":"2018","journal-title":"Int. J. Mol. Med."},{"key":"10.1016\/j.ydbio.2023.02.004_bib63","article-title":"Efficiency of cell therapy to GC-induced ONFH: BMSCs with dkk-1 interference is not superior to unmodified BMSCs","volume":"2018","author":"Zhun","year":"2018","journal-title":"Stem Cell. Int."}],"container-title":["Developmental Biology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0012160623000313?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0012160623000313?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T15:46:44Z","timestamp":1777391204000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0012160623000313"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,4]]},"references-count":63,"alternative-id":["S0012160623000313"],"URL":"https:\/\/doi.org\/10.1016\/j.ydbio.2023.02.004","relation":{"has-preprint":[{"id-type":"doi","id":"10.1101\/2022.06.13.496037","asserted-by":"object"}]},"ISSN":["0012-1606"],"issn-type":[{"value":"0012-1606","type":"print"}],"subject":[],"published":{"date-parts":[[2023,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Connexin43 overexpression promotes bone regeneration by osteogenesis and angiogenesis in rat glucocorticoid-induced osteonecrosis of the femoral head","name":"articletitle","label":"Article Title"},{"value":"Developmental Biology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ydbio.2023.02.004","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2023 Elsevier Inc.","name":"copyright","label":"Copyright"}]}}