{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,23]],"date-time":"2026-05-23T05:04:35Z","timestamp":1779512675826,"version":"3.53.1"},"reference-count":65,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,3,24]],"date-time":"2026-03-24T00:00:00Z","timestamp":1774310400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100011858","name":"African Academy of Sciences","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100011858","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000288","name":"Royal Society","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000288","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000833","name":"Rosetrees Trust","doi-asserted-by":"publisher","award":["PGL24\/100179"],"award-info":[{"award-number":["PGL24\/100179"]}],"id":[{"id":"10.13039\/501100000833","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000848","name":"University of Edinburgh","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000848","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Developmental Biology"],"published-print":{"date-parts":[[2026,6]]},"DOI":"10.1016\/j.ydbio.2026.03.011","type":"journal-article","created":{"date-parts":[[2026,3,17]],"date-time":"2026-03-17T06:17:49Z","timestamp":1773728269000},"page":"160-172","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"C","title":["Chick gonad explant electroporation reveals enhancers for testes determining factor, DMRT1"],"prefix":"10.1016","volume":"534","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6794-6963","authenticated-orcid":false,"given":"Zane","family":"Oberholzer","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0579-9416","authenticated-orcid":false,"given":"G\u00fcne\u015f","family":"Taylor","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2613-6216","authenticated-orcid":false,"given":"Dorit","family":"Hockman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9122-9721","authenticated-orcid":false,"given":"Natalya V.","family":"Nikitina","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"1","key":"10.1016\/j.ydbio.2026.03.011_bib1","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pgen.1009296","article-title":"A regulatory sub-circuit downstream of Wnt signaling controls developmental transitions in neural crest formation","volume":"17","author":"Azambuja","year":"2021","journal-title":"PLoS Genet."},{"key":"10.1016\/j.ydbio.2026.03.011_bib2","author":"Betancur"},{"issue":"1","key":"10.1016\/j.ydbio.2026.03.011_bib3","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1101\/gr.789803","article-title":"AVID: a global alignment program","volume":"13","author":"Bray","year":"2003","journal-title":"Genome Res."},{"key":"10.1016\/j.ydbio.2026.03.011_bib4","article-title":"The khmer software package: enabling efficient nucleotide sequence analysis","volume":"4","author":"Brown","year":"2015","journal-title":"F1000Research"},{"issue":"2","key":"10.1016\/j.ydbio.2026.03.011_bib5","doi-asserted-by":"crossref","DOI":"10.1002\/imt2.107","article-title":"Ultrafast one-pass FASTQ data preprocessing, quality control, and deduplication using fastp","volume":"2","author":"Chen","year":"2023","journal-title":"iMeta"},{"issue":"1","key":"10.1016\/j.ydbio.2026.03.011_bib6","doi-asserted-by":"crossref","first-page":"134","DOI":"10.1080\/713655025","article-title":"Sexing chick embryos : a rapid and simple protocol","volume":"42","author":"Clinton","year":"2001","journal-title":"Br. Poult. Sci."},{"issue":"52","key":"10.1016\/j.ydbio.2026.03.011_bib7","doi-asserted-by":"crossref","first-page":"33305","DOI":"10.1073\/pnas.2009997117","article-title":"Post-transcriptional tuning of FGF signaling mediates neural crest induction","volume":"117","author":"Copeland","year":"2020","journal-title":"Proc. Natl. Acad. Sci. USA"},{"issue":"5319","key":"10.1016\/j.ydbio.2026.03.011_bib8","article-title":"Human sex reversal is caused by duplication or deletion of core enhancers upstream of SOX9","volume":"9","author":"Croft","year":"2018","journal-title":"Nat. Commun."},{"issue":"2","key":"10.1016\/j.ydbio.2026.03.011_bib9","doi-asserted-by":"crossref","DOI":"10.1093\/gigascience\/giab008","article-title":"Twelve years of SAMtools and BCFtools","volume":"10","author":"Danecek","year":"2021","journal-title":"GigaScience"},{"issue":"1","key":"10.1016\/j.ydbio.2026.03.011_bib10","doi-asserted-by":"crossref","DOI":"10.1038\/s41598-023-39536-1","article-title":"Enhanced cultivation of chicken primordial germ cells","volume":"13","author":"Dehdilani","year":"2023","journal-title":"Sci. Rep."},{"issue":"22","key":"10.1016\/j.ydbio.2026.03.011_bib11","doi-asserted-by":"crossref","DOI":"10.1016\/j.jmb.2024.168766","article-title":"The enigma of transcriptional activation domains","volume":"436","author":"Erkine","year":"2024","journal-title":"J. Mol. Biol."},{"issue":"1","key":"10.1016\/j.ydbio.2026.03.011_bib12","doi-asserted-by":"crossref","DOI":"10.1016\/j.celrep.2020.03.055","article-title":"Insights into gonadal sex differentiation provided by single-cell transcriptomics in the chicken embryo","volume":"31","author":"Estermann","year":"2020","journal-title":"Cell Rep."},{"issue":"5","key":"10.1016\/j.ydbio.2026.03.011_bib13","article-title":"DMRT1-mediated regulation of TOX3 modulates expansion of the gonadal steroidogenic cell lineage in the chicken embryo","volume":"150","author":"Estermann","year":"2023","journal-title":"Development (Camb.)"},{"key":"10.1016\/j.ydbio.2026.03.011_bib14","doi-asserted-by":"crossref","DOI":"10.1093\/nar\/gkh458","article-title":"VISTA: computational tools for comparative genomics","volume":"32","author":"Frazer","year":"2004","journal-title":"Nucleic Acids Res."},{"issue":"5","key":"10.1016\/j.ydbio.2026.03.011_bib15","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pgen.1007895","article-title":"CBX2 is required to stabilize the testis pathway by repressing wnt signaling","volume":"15","author":"Garcia-Moreno","year":"2019","journal-title":"PLoS Genet."},{"key":"10.1016\/j.ydbio.2026.03.011_bib16","doi-asserted-by":"crossref","first-page":"1469","DOI":"10.1126\/science.aas9408","article-title":"Sex reversal following deletion of a single distal enhancer of Sox9","volume":"360","author":"Gonen","year":"2018","journal-title":"Science"},{"key":"10.1016\/j.ydbio.2026.03.011_bib17","doi-asserted-by":"crossref","first-page":"797","DOI":"10.1002\/dvdy.21907","article-title":"The RCAS retroviral expression system in the study of skeletal development","author":"Gordon","year":"2009","journal-title":"Dev. Dyn."},{"issue":"4","key":"10.1016\/j.ydbio.2026.03.011_bib18","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1002\/aja.1001950404","article-title":"A series of normal stages in the development of the chick embryo","volume":"195","author":"Hamburger","year":"1992","journal-title":"Dev. Dyn."},{"issue":"8","key":"10.1016\/j.ydbio.2026.03.011_bib19","doi-asserted-by":"crossref","first-page":"895","DOI":"10.1038\/ng.3605","article-title":"Genetic dissection of the \u03b1-globin super-enhancer in vivo","volume":"48","author":"Hay","year":"2016","journal-title":"Nat. Genet."},{"key":"10.1016\/j.ydbio.2026.03.011_bib20","doi-asserted-by":"crossref","first-page":"107","DOI":"10.14712\/fb2004050030107","article-title":"The RCAS vector system","volume":"50","author":"Hughes","year":"2004","journal-title":"Folia Biol."},{"issue":"4","key":"10.1016\/j.ydbio.2026.03.011_bib21","doi-asserted-by":"crossref","first-page":"242","DOI":"10.1111\/gtc.12753","article-title":"Sox2 gene regulation via the D1 enhancer in embryonic neural tube and neural crest by the combined action of SOX2 and ZIC2","volume":"25","author":"Iida","year":"2020","journal-title":"Genes Cells"},{"issue":"9","key":"10.1016\/j.ydbio.2026.03.011_bib22","doi-asserted-by":"crossref","first-page":"1049","DOI":"10.1111\/j.1365-2443.2007.01114.x","article-title":"PAX6 and SOX2-dependent regulation of the Sox2 enhancer N-3 involved in embryonic visual system development","volume":"12","author":"Inoue","year":"2007","journal-title":"Genes Cells"},{"issue":"10","key":"10.1016\/j.ydbio.2026.03.011_bib23","doi-asserted-by":"crossref","DOI":"10.1073\/pnas.2020909118","article-title":"Primary sex determination in birds depends on DMRT1 dosage, but gonadal sex does not determine adult secondary sex characteristics","volume":"118","author":"Ioannidis","year":"2021","journal-title":"Proc. Natl. Acad. Sci. U. S. A"},{"issue":"DATABASE ISS","key":"10.1016\/j.ydbio.2026.03.011_bib24","article-title":"The UCSC table browser data retrieval tool","volume":"32","author":"Karolchik","year":"2004","journal-title":"Nucleic Acids Res."},{"issue":"17","key":"10.1016\/j.ydbio.2026.03.011_bib25","doi-asserted-by":"crossref","first-page":"2204","DOI":"10.1093\/bioinformatics\/btq351","article-title":"BigWig and BigBed: enabling browsing of large distributed datasets","volume":"26","author":"Kent","year":"2010","journal-title":"Bioinformatics"},{"key":"10.1016\/j.ydbio.2026.03.011_bib26","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1038\/351117a0","article-title":"Male development of chromosomally female mice transgenic for sry","volume":"351","author":"Koopman","year":"1991","journal-title":"Nature"},{"issue":"2","key":"10.1016\/j.ydbio.2026.03.011_bib27","doi-asserted-by":"crossref","first-page":"160","DOI":"10.1016\/j.ydbio.2014.02.012","article-title":"Over-expression of DMRT1 induces the Male pathway in embryonic chicken gonads","volume":"389","author":"Lambeth","year":"2014","journal-title":"Dev. Biol."},{"issue":"7","key":"10.1016\/j.ydbio.2026.03.011_bib28","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0101811","article-title":"Development of retroviral vectors for tissue-restricted expression in chicken embryonic gonads","volume":"9","author":"Lambeth","year":"2014","journal-title":"PLoS One"},{"issue":"4","key":"10.1016\/j.ydbio.2026.03.011_bib29","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1038\/nmeth.1923","article-title":"Fast gapped-read alignment with bowtie 2","volume":"9","author":"Langmead","year":"2012","journal-title":"Nat. Methods"},{"issue":"3","key":"10.1016\/j.ydbio.2026.03.011_bib30","doi-asserted-by":"crossref","first-page":"394","DOI":"10.1002\/elps.201000392","article-title":"A PCR amplification method without DNA extraction","volume":"32","author":"Li","year":"2011","journal-title":"Electrophoresis"},{"key":"10.1016\/j.ydbio.2026.03.011_bib31","article-title":"Time-course transcriptional and chromatin accessibility profiling reveals genes associated with asymmetrical gonadal development in chicken embryos","volume":"10","author":"Li","year":"2022","journal-title":"Front. Cell Dev. Biol."},{"key":"10.1016\/j.ydbio.2026.03.011_bib32","article-title":"Single-nucleus transcriptional and chromatin accessible profiles reveal critical cell types and molecular architecture underlying chicken sex determination","author":"Li","year":"2024","journal-title":"J. Adv. Res."},{"issue":"7","key":"10.1016\/j.ydbio.2026.03.011_bib33","doi-asserted-by":"crossref","first-page":"3237","DOI":"10.1210\/en.2002-0095","article-title":"Etiology of ovarian failure in blepharophimosis ptosis epicanthus inversus syndrome: FOXL2 is a conserved, early-acting gene in vertebrate ovarian development","volume":"144","author":"Loffler","year":"2003","journal-title":"Endocrinology"},{"issue":"1","key":"10.1016\/j.ydbio.2026.03.011_bib34","doi-asserted-by":"crossref","DOI":"10.1038\/s41467-021-21426-7","article-title":"Characterising open chromatin in chick embryos identifies cis-regulatory elements important for paraxial mesoderm formation and axis extension","volume":"12","author":"Mok","year":"2021","journal-title":"Nat. Commun."},{"key":"10.1016\/j.ydbio.2026.03.011_bib35","doi-asserted-by":"crossref","DOI":"10.1038\/ncomms8720","article-title":"Evolution of dosage compensation under sexual selection differs between X and Z chromosomes","volume":"6","author":"Mullon","year":"2015","journal-title":"Nat. Commun."},{"issue":"1","key":"10.1016\/j.ydbio.2026.03.011_bib36","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1016\/j.ydbio.2016.12.004","article-title":"Tissue specific regulation of the chick Sox10E1 enhancer by different sox family members","volume":"422","author":"Murko","year":"2017","journal-title":"Dev. Biol."},{"issue":"3","key":"10.1016\/j.ydbio.2026.03.011_bib37","doi-asserted-by":"crossref","first-page":"714","DOI":"10.3390\/biology1030714","article-title":"A systematic survey and characterization of enhancers that regulate Sox3 in neuro-sensory development in comparison with Sox2 enhancers","volume":"1","author":"Nishimura","year":"2012","journal-title":"Biology"},{"key":"10.1016\/j.ydbio.2026.03.011_bib38","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1111\/dgd.12427","article-title":"Cooperation of Sall4 and Sox8 transcription factors in the regulation of the chicken Sox3 gene during otic placode development","volume":"60","author":"Okamoto","year":"2018","journal-title":"Dev. Growth Differ."},{"key":"10.1016\/j.ydbio.2026.03.011_bib39","doi-asserted-by":"crossref","first-page":"9123","DOI":"10.1073\/pnas.84.24.9123","article-title":"Detection in situ of genomic regulatory elements in drosophila","volume":"84","author":"O\u2019kane","year":"1987","journal-title":"Proc. Natl. Acad. Sci. USA"},{"issue":"14","key":"10.1016\/j.ydbio.2026.03.011_bib40","doi-asserted-by":"crossref","first-page":"2053","DOI":"10.1093\/hmg\/ddi210","article-title":"Foxl2 is required for commitment to ovary differentiation","volume":"14","author":"Ottolenghi","year":"2005","journal-title":"Hum. Mol. Genet."},{"issue":"D1","key":"10.1016\/j.ydbio.2026.03.011_bib41","doi-asserted-by":"crossref","first-page":"D1243","DOI":"10.1093\/nar\/gkae974","article-title":"The UCSC genome browser database: 2025 update","volume":"53","author":"Perez","year":"2025","journal-title":"Nucleic Acids Res."},{"issue":"W1","key":"10.1016\/j.ydbio.2026.03.011_bib42","doi-asserted-by":"crossref","first-page":"W160","DOI":"10.1093\/nar\/gkw257","article-title":"deepTools2: a next generation web server for deep-sequencing data analysis","volume":"44","author":"Ram\u00edrez","year":"2016","journal-title":"Nucleic Acids Res."},{"issue":"1","key":"10.1016\/j.ydbio.2026.03.011_bib43","doi-asserted-by":"crossref","first-page":"D174","DOI":"10.1093\/nar\/gkad1059","article-title":"Jaspar 2024: 20th anniversary of the open-access database of transcription factor binding profiles","volume":"52","author":"Rauluseviciute","year":"2024","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.ydbio.2026.03.011_bib44","doi-asserted-by":"crossref","first-page":"1654","DOI":"10.1016\/j.csbj.2022.03.040","article-title":"Dissecting chicken germ cell dynamics by combining a germ cell tracing transgenic chicken model with single-cell RNA sequencing","volume":"20","author":"Rengaraj","year":"2022","journal-title":"Comput. Struct. Biotechnol. J."},{"issue":"1","key":"10.1016\/j.ydbio.2026.03.011_bib45","doi-asserted-by":"crossref","first-page":"346","DOI":"10.1002\/dvdy.22174","article-title":"Real-time observation of Wnt \u03b2-catenin signaling in the chick embryo","volume":"239","author":"Rios","year":"2010","journal-title":"Dev. Dyn."},{"key":"10.1016\/j.ydbio.2026.03.011_bib46","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1038\/nbt.1754","article-title":"Integrative genomics viewer","author":"Robinson","year":"2011","journal-title":"Nat. Biotechnol."},{"key":"10.1016\/j.ydbio.2026.03.011_bib47","doi-asserted-by":"crossref","DOI":"10.7554\/eLife.68068","article-title":"Simple biochemical features underlie transcriptional activation domain diversity and dynamic, fuzzy binding to mediator","volume":"10","author":"Sanborn","year":"2021","journal-title":"eLife"},{"key":"10.1016\/j.ydbio.2026.03.011_bib48","series-title":"Avian Embryology. 2nd Editio","first-page":"237","article-title":"Gain - and loss-of-function approaches in the chick embryo","author":"Sauka-spengler","year":"2008"},{"key":"10.1016\/j.ydbio.2026.03.011_bib49","doi-asserted-by":"crossref","first-page":"676","DOI":"10.1038\/nmeth.2019","article-title":"Fiji: an open-source platform for biological-image analysis","author":"Schindelin","year":"2012","journal-title":"Nat. Methods"},{"issue":"7197","key":"10.1016\/j.ydbio.2026.03.011_bib50","doi-asserted-by":"crossref","first-page":"930","DOI":"10.1038\/nature06944","article-title":"Sex determination involves synergistic action of SRY and SF1 on a specific Sox9 enhancer","volume":"453","author":"Sekido","year":"2008","journal-title":"Nature"},{"key":"10.1016\/j.ydbio.2026.03.011_bib51","doi-asserted-by":"crossref","first-page":"240","DOI":"10.1038\/346240a0","article-title":"A gene from the human sex-determining region encodes a protein with homology to a conserved DNA-binding motif","volume":"346","author":"Sinclair","year":"1990","journal-title":"Nature"},{"issue":"2","key":"10.1016\/j.ydbio.2026.03.011_bib52","doi-asserted-by":"crossref","first-page":"337","DOI":"10.1016\/j.ydbio.2005.05.030","article-title":"Male-specific cell migration into the developing gonad is a conserved process involving PDGF signalling","volume":"284","author":"Smith","year":"2005","journal-title":"Dev. Biol."},{"issue":"7261","key":"10.1016\/j.ydbio.2026.03.011_bib53","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1038\/nature08298","article-title":"The avian Z-linked gene DMRT1 is required for male sex determination in the chicken","volume":"461","author":"Smith","year":"2009","journal-title":"Nature"},{"issue":"1","key":"10.1016\/j.ydbio.2026.03.011_bib54","article-title":"Dmrt1 is required for primary male sexual differentiation in Chinese soft-shelled turtle Pelodiscus sinensis","volume":"7","author":"Sun","year":"2017","journal-title":"Sci. Rep."},{"issue":"3","key":"10.1016\/j.ydbio.2026.03.011_bib55","first-page":"69","article-title":"Enhancer activation by FGF signalling during otic induction","volume":"9","author":"Tambalo","year":"2020","journal-title":"Mol. Cells"},{"issue":"3","key":"10.1016\/j.ydbio.2026.03.011_bib56","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1002\/gene.1015","article-title":"The use of in ovo electroporation for the rapid analysis of neural-specific murine enhancers","volume":"29","author":"Timmer","year":"2001","journal-title":"Genesis"},{"issue":"4","key":"10.1016\/j.ydbio.2026.03.011_bib57","doi-asserted-by":"crossref","first-page":"509","DOI":"10.1016\/S1534-5807(03)00088-1","article-title":"Functional analysis of chicken Sox2 enhancers highlights an array of diverse regulatory elements that are conserved in mammals","volume":"4","author":"Uchikawa","year":"2003","journal-title":"Dev. Cell"},{"key":"10.1016\/j.ydbio.2026.03.011_bib58","doi-asserted-by":"crossref","DOI":"10.1016\/j.sbi.2023.102732","article-title":"Commonly asked questions about transcriptional activation domains","volume":"84","author":"Udupa","year":"2024","journal-title":"Curr. Opin. Struct. Biol."},{"issue":"Suppl. 1","key":"10.1016\/j.ydbio.2026.03.011_bib59","doi-asserted-by":"crossref","first-page":"88","DOI":"10.1093\/nar\/gkl822","article-title":"VISTA enhancer browser - a database of tissue-specific human enhancers","volume":"35","author":"Visel","year":"2007","journal-title":"Nucleic Acids Res."},{"issue":"1","key":"10.1016\/j.ydbio.2026.03.011_bib60","doi-asserted-by":"crossref","first-page":"88","DOI":"10.1093\/nar\/gkr734","article-title":"Transcription factor Sox10 orchestrates activity of a neural crest-specific enhancer in the vicinity of its gene","volume":"40","author":"Wahlbuhl","year":"2012","journal-title":"Nucleic Acids Res."},{"issue":"10","key":"10.1016\/j.ydbio.2026.03.011_bib61","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pbio.3002786","article-title":"Chromatin remodeller Chd7 is developmentally regulated in the neural crest by tissue-specific transcription factors","volume":"22","author":"Williams","year":"2024","journal-title":"PLoS Biol."},{"key":"10.1016\/j.ydbio.2026.03.011_bib62","doi-asserted-by":"crossref","DOI":"10.1186\/1471-2164-12-91","article-title":"General lack of global dosage compensation in ZZ\/ZW systems? Broadening the perspective with RNA-seq","volume":"12","author":"Wolf","year":"2011","journal-title":"BMC Genom."},{"key":"10.1016\/j.ydbio.2026.03.011_bib63","doi-asserted-by":"crossref","DOI":"10.3389\/fcell.2023.1215406","article-title":"Sox, fox, and Lmx1b binding sites differentially regulate a Gdf5-Associated regulatory region during elbow development","volume":"11","author":"Yeboah","year":"2023","journal-title":"Front. Cell Dev. Biol."},{"issue":"1","key":"10.1016\/j.ydbio.2026.03.011_bib64","doi-asserted-by":"crossref","DOI":"10.1186\/s13072-022-00476-1","article-title":"ATAC-seq and RNA-seq analysis unravel the mechanism of sex differentiation and infertility in sex reversal chicken","volume":"16","author":"Zhang","year":"2023","journal-title":"Epigenetics Chromatin"},{"issue":"9","key":"10.1016\/j.ydbio.2026.03.011_bib65","doi-asserted-by":"crossref","DOI":"10.1186\/gb-2008-9-9-r137","article-title":"Model-based analysis of ChIP-Seq (MACS)","volume":"9","author":"Zhang","year":"2008","journal-title":"Genome Biol."}],"container-title":["Developmental Biology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0012160626000679?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0012160626000679?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,5,23]],"date-time":"2026-05-23T04:11:14Z","timestamp":1779509474000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0012160626000679"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,6]]},"references-count":65,"alternative-id":["S0012160626000679"],"URL":"https:\/\/doi.org\/10.1016\/j.ydbio.2026.03.011","relation":{},"ISSN":["0012-1606"],"issn-type":[{"value":"0012-1606","type":"print"}],"subject":[],"published":{"date-parts":[[2026,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Chick gonad explant electroporation reveals enhancers for testes determining factor, DMRT1","name":"articletitle","label":"Article Title"},{"value":"Developmental Biology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ydbio.2026.03.011","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 The Authors. Published by Elsevier Inc.","name":"copyright","label":"Copyright"}]}}