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Chem."},{"key":"10.1016\/j.ydbio.2026.04.004_bib95","doi-asserted-by":"crossref","first-page":"585","DOI":"10.3109\/00365518209168134","article-title":"Thyroid hormone resistance in a 35-year old man with recurrent goitre","volume":"42","author":"Lindstedt","year":"1982","journal-title":"Scand. J. Clin. Lab. Invest."},{"key":"10.1016\/j.ydbio.2026.04.004_bib96","doi-asserted-by":"crossref","first-page":"749","DOI":"10.1523\/JNEUROSCI.4832-07.2008","article-title":"NeuroD1 regulates expression of thyroid hormone receptor \u03b22 and cone opsins in the developing mouse retina","volume":"28","author":"Liu","year":"2008","journal-title":"J. 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A."},{"key":"10.1016\/j.ydbio.2026.04.004_bib101","doi-asserted-by":"crossref","DOI":"10.1242\/dev.198549","article-title":"Cis-regulatory dissection of cone development reveals a broad role for Otx2 and Oc transcription factors","volume":"148","author":"Lonfat","year":"2021","journal-title":"Development"},{"key":"10.1016\/j.ydbio.2026.04.004_bib102","doi-asserted-by":"crossref","first-page":"1536","DOI":"10.1210\/en.2008-1092","article-title":"Retarded developmental expression and patterning of retinal cone opsins in hypothyroid mice","volume":"150","author":"Lu","year":"2009","journal-title":"Endocrinology"},{"key":"10.1016\/j.ydbio.2026.04.004_bib103","doi-asserted-by":"crossref","DOI":"10.15252\/embj.2018100811","article-title":"A single-cell transcriptome atlas of the adult human retina","volume":"38","author":"Lukowski","year":"2019","journal-title":"EMBO J."},{"key":"10.1016\/j.ydbio.2026.04.004_bib104","doi-asserted-by":"crossref","first-page":"442","DOI":"10.1523\/JNEUROSCI.19-01-00442.1999","article-title":"UV- and midwave-sensitive cone-driven retinal responses of the mouse: a possible phenotype for coexpression of cone photopigments","volume":"19","author":"Lyubarsky","year":"1999","journal-title":"J. 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A."},{"key":"10.1016\/j.ydbio.2026.04.004_bib109","doi-asserted-by":"crossref","first-page":"1240","DOI":"10.3390\/genes16101240","article-title":"Mutation of the thyroid hormone receptor beta gene (THRB) causes vitelliform macular dystrophy with high intrafamilial variability","volume":"16","author":"Mahler","year":"2025","journal-title":"Genes"},{"key":"10.1016\/j.ydbio.2026.04.004_bib110","doi-asserted-by":"crossref","first-page":"835","DOI":"10.1016\/0092-8674(95)90199-X","article-title":"The nuclear receptor superfamily: the second decade","volume":"83","author":"Mangelsdorf","year":"1995","journal-title":"Cell"},{"key":"10.1016\/j.ydbio.2026.04.004_bib111","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1038\/ng0598-87","article-title":"Follicular cells of the thyroid gland require Pax8 gene function","volume":"19","author":"Mansouri","year":"1998","journal-title":"Nat. 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