{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,2]],"date-time":"2026-06-02T17:38:46Z","timestamp":1780421926423,"version":"3.54.1"},"reference-count":14,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2005,3,1]],"date-time":"2005-03-01T00:00:00Z","timestamp":1109635200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Epilepsy & Behavior"],"published-print":{"date-parts":[[2005,3]]},"DOI":"10.1016\/j.yebeh.2004.11.014","type":"journal-article","created":{"date-parts":[[2005,1,15]],"date-time":"2005-01-15T12:30:36Z","timestamp":1105792236000},"page":"260-263","source":"Crossref","is-referenced-by-count":25,"title":["Add-on therapy with topiramate in progressive myoclonic epilepsy"],"prefix":"10.1016","volume":"6","author":[{"given":"Ebru","family":"Aykutlu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bet\u00fcl","family":"Baykan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Candan","family":"G\u00fcrses","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nerses","family":"Bebek","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nesimi","family":"B\u00fcy\u00fckbabani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ay\u015fen","family":"G\u00f6kyig\u02c7it","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.yebeh.2004.11.014_bib1","series-title":"Epileptic syndromes in infancy, childhood and adolescence","first-page":"407","article-title":"Progressive myoclonus epilepsies","author":"Genton","year":"2002"},{"key":"10.1016\/j.yebeh.2004.11.014_bib2","series-title":"Epilepsy and movement disorders","first-page":"227","article-title":"Seizures, myoclonus and cerebellar dysfunction in progressive myoclonus epilepsies","author":"Michelucci","year":"2002"},{"issue":"Suppl. 3","key":"10.1016\/j.yebeh.2004.11.014_bib3","first-page":"S19","article-title":"Progressive myoclonus epilepsies: clinical and genetic aspects","volume":"34","author":"Berkovic","year":"1993","journal-title":"Epilepsia"},{"key":"10.1016\/j.yebeh.2004.11.014_bib4","doi-asserted-by":"crossref","first-page":"334","DOI":"10.1136\/jnnp.64.3.344","article-title":"Piracetam relieves symptoms in progressive myoclonus epilepsy: a multicentre, randomised, double blind, crossover study comparing the efficacy and safety of three dosages of oral piracetam with placebo","volume":"64","author":"Koskiniemi","year":"1998","journal-title":"J Neurol Neurosurg Psychiatry"},{"key":"10.1016\/j.yebeh.2004.11.014_bib5","doi-asserted-by":"crossref","first-page":"781","DOI":"10.1001\/archneur.58.5.781","article-title":"Long-term efficacy and safety of piracetam in the treatment of progressive myoclonus epilepsy","volume":"58","author":"Fedi","year":"2001","journal-title":"Arch Neurol"},{"key":"10.1016\/j.yebeh.2004.11.014_bib6","doi-asserted-by":"crossref","first-page":"640","DOI":"10.1212\/01.WNL.0000110193.78872.DD","article-title":"Levetiracetam in progressive myoclonic epilepsy: an exploratory study in 9 patients","volume":"62","author":"Crest","year":"2004","journal-title":"Neurology"},{"key":"10.1016\/j.yebeh.2004.11.014_bib7","doi-asserted-by":"crossref","first-page":"678","DOI":"10.1111\/j.0013-9580.2004.56902.x","article-title":"Antimyoclonic effect of levetiracetam in 13 patients with Unverricht\u2013Lundborg disease: clinical observations","volume":"45","author":"Magaudda","year":"2004","journal-title":"Epilepsia"},{"key":"10.1016\/j.yebeh.2004.11.014_bib8","doi-asserted-by":"crossref","first-page":"928","DOI":"10.1212\/WNL.38.6.928","article-title":"Progressive myoclonus epilepsy treated with zonisamide","volume":"38","author":"Henry","year":"1988","journal-title":"Neurology"},{"key":"10.1016\/j.yebeh.2004.11.014_bib9","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1016\/S0920-1211(97)00069-7","article-title":"Zonisamide for progressive myoclonus epilepsy: long-term observations in seven patients","volume":"29","author":"Kyllerman","year":"1998","journal-title":"Epilepsy Res"},{"key":"10.1016\/j.yebeh.2004.11.014_bib10","doi-asserted-by":"crossref","unstructured":"Topiramate YTC\/YTCE Study Group. Nonfocal generalized tonic\u2013clonic seizures: response during long-term topiramate treatment. Epilepsia 2000;41(Suppl. 1): S77\u201381","DOI":"10.1111\/j.1528-1157.2000.tb02177.x"},{"key":"10.1016\/j.yebeh.2004.11.014_bib11","doi-asserted-by":"crossref","first-page":"1264","DOI":"10.1212\/WNL.47.5.1264","article-title":"Treatment of four siblings with progressive myoclonus epilepsy of the Unverricht\u2013Lundborg type with N-acetylcysteine","volume":"47","author":"Hurd","year":"1996","journal-title":"Neurology"},{"key":"10.1016\/j.yebeh.2004.11.014_bib12","first-page":"11","article-title":"Pharmacokinetic properties of current antiepileptic drugs: what improvements are needed?","volume":"55","author":"Bourgeois","year":"2000","journal-title":"Neurology"},{"key":"10.1016\/j.yebeh.2004.11.014_bib13","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1111\/j.1528-1157.1997.tb04512.x","article-title":"Pharmacokinetics and interaction profile of topiramate: review and comparison with other newer antiepileptic drugs","volume":"38","author":"Johannessen","year":"1997","journal-title":"Epilepsia"},{"key":"10.1016\/j.yebeh.2004.11.014_bib14","doi-asserted-by":"crossref","first-page":"277","DOI":"10.1016\/S0387-7604(01)00230-3","article-title":"Newer antiepileptic drugs: advantages and disadvantages","volume":"23","author":"Wallace","year":"2001","journal-title":"Brain Dev"}],"container-title":["Epilepsy & Behavior"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1525505004003579?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1525505004003579?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,1,30]],"date-time":"2019-01-30T07:20:22Z","timestamp":1548832822000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1525505004003579"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2005,3]]},"references-count":14,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2005,3]]}},"alternative-id":["S1525505004003579"],"URL":"https:\/\/doi.org\/10.1016\/j.yebeh.2004.11.014","relation":{},"ISSN":["1525-5050"],"issn-type":[{"value":"1525-5050","type":"print"}],"subject":[],"published":{"date-parts":[[2005,3]]}}}