{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T16:02:17Z","timestamp":1791388937147,"version":"4.3.3"},"reference-count":46,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2007,5,1]],"date-time":"2007-05-01T00:00:00Z","timestamp":1177977600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Epilepsy &amp; Behavior"],"published-print":{"date-parts":[[2007,5]]},"DOI":"10.1016\/j.yebeh.2007.01.004","type":"journal-article","created":{"date-parts":[[2007,2,16]],"date-time":"2007-02-16T12:23:05Z","timestamp":1171628585000},"page":"417-425","source":"Crossref","is-referenced-by-count":102,"title":["Sertraline and fluoxetine: Safe treatments for children and adolescents with epilepsy and depression"],"prefix":"10.1016","volume":"10","author":[{"given":"M.S.","family":"Thom\u00e9-Souza","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"E.","family":"Kuczynski","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"K.D.","family":"Valente","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.yebeh.2007.01.004_bib1","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1016\/0920-1211(96)00017-4","article-title":"The associations of psychopathology in epilepsy: a community study","volume":"25","author":"Baker","year":"1996","journal-title":"Epilepsy Res"},{"key":"10.1016\/j.yebeh.2007.01.004_bib2","series-title":"Epilepsy: a comprehensive textbook","first-page":"2083","article-title":"Affective disorders","author":"Blumer","year":"1997"},{"key":"10.1016\/j.yebeh.2007.01.004_bib3","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1192\/bjp.151.1.95","article-title":"Relationship between interictal psychopathology and the type of epilepsy: results of a survey in general practice","volume":"151","author":"Edeh","year":"1987","journal-title":"Br J Psychiatry"},{"key":"10.1016\/j.yebeh.2007.01.004_bib4","doi-asserted-by":"crossref","first-page":"785","DOI":"10.1097\/00004583-199706000-00015","article-title":"Recurrence of major depressive disorder in hospitalized children and adolescents","volume":"36","author":"Emslie","year":"1997","journal-title":"J Am Acad Child Adolesc Psychiatry"},{"key":"10.1016\/j.yebeh.2007.01.004_bib5","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1016\/0920-1211(92)90090-G","article-title":"Interictal depression in epilepsy","volume":"12","author":"Indaco","year":"1992","journal-title":"Epilepsy Res"},{"key":"10.1016\/j.yebeh.2007.01.004_bib6","doi-asserted-by":"crossref","first-page":"148","DOI":"10.1111\/j.1528-1157.1996.tb00006.x","article-title":"The clinical course of epilepsy and its psychosocial correlates: findings from a UK community study","volume":"37","author":"Jacoby","year":"1996","journal-title":"Epilepsia"},{"key":"10.1016\/j.yebeh.2007.01.004_bib7","doi-asserted-by":"crossref","first-page":"643","DOI":"10.1001\/archpsyc.1984.01790180013001","article-title":"Depressive disorders in childhood: II. A longitudinal study of the risk for a subsequent major depression","volume":"41","author":"Kovacs","year":"1984","journal-title":"Arch Gen Psychiatry"},{"issue":"Suppl. 10","key":"10.1016\/j.yebeh.2007.01.004_bib8","doi-asserted-by":"crossref","first-page":"S21","DOI":"10.1111\/j.1528-1157.1999.tb00884.x","article-title":"Depression in epilepsy: etiology, phenomenology, and treatment","volume":"40","author":"Lambert","year":"1999","journal-title":"Epilepsia"},{"key":"10.1016\/j.yebeh.2007.01.004_bib9","doi-asserted-by":"crossref","first-page":"766","DOI":"10.1001\/archneur.1986.00520080014012","article-title":"Depression in epilepsy: significance and phenomenology","volume":"43","author":"Mendez","year":"1986","journal-title":"Arch Neurol"},{"key":"10.1016\/j.yebeh.2007.01.004_bib10","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1038\/scientificamerican0698-42","article-title":"The neurobiology of depression","volume":"278","author":"Nemeroff","year":"1998","journal-title":"Sci Am"},{"key":"10.1016\/j.yebeh.2007.01.004_bib11","doi-asserted-by":"crossref","first-page":"100","DOI":"10.1006\/ebeh.2000.0050","article-title":"The use of sertraline in patients with epilepsy: is it safe?","volume":"1","author":"Kanner","year":"2000","journal-title":"Epilepsy Behav"},{"issue":"Suppl. 2","key":"10.1016\/j.yebeh.2007.01.004_bib12","first-page":"S3","article-title":"Co-morbid psychiatric disorder in chronic epilepsy: recognition and etiology of depression","volume":"53","author":"Wiegartz","year":"1999","journal-title":"Neurology"},{"key":"10.1016\/j.yebeh.2007.01.004_bib13","doi-asserted-by":"crossref","first-page":"809","DOI":"10.1097\/00004583-199407000-00006","article-title":"Major depression in community adolescents: age at onset, episode duration, and time to recurrence","volume":"33","author":"Lewinsohn","year":"1994","journal-title":"J Am Acad Child Adolesc Psychiatry"},{"key":"10.1016\/j.yebeh.2007.01.004_bib14","doi-asserted-by":"crossref","first-page":"988","DOI":"10.1016\/j.yebeh.2004.09.001","article-title":"Which factors may play a pivotal role in determining the type of psychiatric disorder in children and adolescents with epilepsy?","volume":"5","author":"Thome-Souza","year":"2004","journal-title":"Epilepsy Behav"},{"issue":"62","key":"10.1016\/j.yebeh.2007.01.004_bib15","doi-asserted-by":"crossref","first-page":"258","DOI":"10.1212\/01.WNL.0000103282.62353.85","article-title":"Depression but not seizure frequency predicts quality of life in treatment-resistant epilepsy","volume":"27","author":"Boylan","year":"2004","journal-title":"Neurology"},{"key":"10.1016\/j.yebeh.2007.01.004_bib16","doi-asserted-by":"crossref","unstructured":"Gilliam F. Optimizing health outcomes in active epilepsy. Neurology 2002;23;58(8, Suppl. 5):S9\u201320.","DOI":"10.1212\/WNL.58.8_suppl_5.S9"},{"issue":"Suppl. 2","key":"10.1016\/j.yebeh.2007.01.004_bib17","doi-asserted-by":"crossref","first-page":"S109","DOI":"10.1111\/j.1528-1157.1983.tb04647.x","article-title":"Depressive illness in patients with epilepsy: a review","volume":"24","author":"Robertson","year":"1983","journal-title":"Epilepsia"},{"key":"10.1016\/j.yebeh.2007.01.004_bib18","doi-asserted-by":"crossref","first-page":"666","DOI":"10.1016\/S0002-7138(09)60292-2","article-title":"Psychopathology and its relationship to suicidal ideation in childhood and adolescence","volume":"25","author":"Brent","year":"1986","journal-title":"J Am Acad Child Psychiatry"},{"key":"10.1016\/j.yebeh.2007.01.004_bib19","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1097\/00004583-198701000-00017","article-title":"Correlates of the medical lethality of suicide attempts in children and adolescents","volume":"26","author":"Brent","year":"1987","journal-title":"J Am Acad Child Adolesc Psychiatry"},{"key":"10.1016\/j.yebeh.2007.01.004_bib20","doi-asserted-by":"crossref","first-page":"587","DOI":"10.1097\/00004583-199007000-00012","article-title":"Suicidality in affectively disordered adolescent inpatients","volume":"29","author":"Brent","year":"1990","journal-title":"J Am Acad Child Adolesc Psychiatry"},{"issue":"Suppl. 5","key":"10.1016\/j.yebeh.2007.01.004_bib21","doi-asserted-by":"crossref","first-page":"S27","DOI":"10.1212\/WNL.58.8_suppl_5.S27","article-title":"Depression and epilepsy: how close are they?","volume":"58","author":"Kanner","year":"2002","journal-title":"Neurology"},{"key":"10.1016\/j.yebeh.2007.01.004_bib22","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1176\/appi.ajp.158.1.125","article-title":"Bipolar disorder at prospective follow-up of adults who had prepubertal major depressive disorder","volume":"158","author":"Geller","year":"2001","journal-title":"Am J Psychiatry"},{"key":"10.1016\/j.yebeh.2007.01.004_bib23","doi-asserted-by":"crossref","first-page":"1287","DOI":"10.1111\/j.1469-7610.1992.tb00950.x","article-title":"The natural history and treatment of child and adolescent affective disorders","volume":"33","author":"Harrington","year":"1992","journal-title":"J Child Psychol Psychiatry"},{"issue":"Suppl. 2","key":"10.1016\/j.yebeh.2007.01.004_bib24","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1046\/j.1528-1157.2002.043s2014.x","article-title":"Antidepressant drugs: indications and guidelines for use in epilepsy","volume":"43","author":"Schmitz","year":"2002","journal-title":"Epilepsia"},{"key":"10.1016\/j.yebeh.2007.01.004_bib25","doi-asserted-by":"crossref","first-page":"1423","DOI":"10.1016\/0024-3205(67)90190-7","article-title":"Audiogenic seizure data in mice supporting new theories of biogenic amines mechanisms in the central nervous system","volume":"6","author":"Lehmann","year":"1967","journal-title":"Life Sci"},{"key":"10.1016\/j.yebeh.2007.01.004_bib26","doi-asserted-by":"crossref","first-page":"212","DOI":"10.1007\/BF00432547","article-title":"Anticonvulsant and proconvulsant properties of viloxazine hydrochloride: pharmacological and pharmacokinetic studies in rodents and epileptic baboon","volume":"76","author":"Meldrum","year":"1982","journal-title":"Psychopharmacology (Berlin)"},{"key":"10.1016\/j.yebeh.2007.01.004_bib27","doi-asserted-by":"crossref","first-page":"1926","DOI":"10.1212\/WNL.45.10.1926","article-title":"Anticonvulsant effect of fluoxetine in humans","volume":"45","author":"Favale","year":"1995","journal-title":"Neurology"},{"key":"10.1016\/j.yebeh.2007.01.004_bib28","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1097\/00002826-200405000-00009","article-title":"Citalopram as treatment of depression in patients with epilepsy","volume":"27","author":"Specchio","year":"2004","journal-title":"Clin Neuropharmacol"},{"key":"10.1016\/j.yebeh.2007.01.004_bib29","doi-asserted-by":"crossref","first-page":"471","DOI":"10.1016\/j.pnpbp.2005.11.016","article-title":"Symptoms of depression as possible markers of bipolar II disorder","volume":"30","author":"Benazzi","year":"2006","journal-title":"Prog Neuropsychopharmacol Biol Psychiatry"},{"key":"10.1016\/j.yebeh.2007.01.004_bib30","doi-asserted-by":"crossref","first-page":"591","DOI":"10.1046\/j.1528-1157.2003.25002.x","article-title":"Behavioral disorders in pediatric epilepsy: unmet psychiatric need","volume":"4","author":"Ott","year":"2003","journal-title":"Epilepsia"},{"key":"10.1016\/j.yebeh.2007.01.004_bib31","doi-asserted-by":"crossref","first-page":"3","DOI":"10.4088\/JCP.v58n0101","article-title":"Antidepressant and double antidepressant treatment for the affective disorder of epilepsy","volume":"58","author":"Blumer","year":"1997","journal-title":"J Clin Psychiatry"},{"key":"10.1016\/j.yebeh.2007.01.004_bib32","doi-asserted-by":"crossref","first-page":"S39","DOI":"10.1016\/j.yebeh.2003.08.016","article-title":"Depression in children and adolescents with epilepsy","volume":"4","author":"Plioplys","year":"2003","journal-title":"Epilepsy Behav"},{"key":"10.1016\/j.yebeh.2007.01.004_bib33","doi-asserted-by":"crossref","first-page":"1043","DOI":"10.1016\/j.pnpbp.2006.03.037","article-title":"A continuity between bipolar II depression and major depressive disorder?","volume":"30","author":"Benazzi","year":"2006","journal-title":"Prog Neuropsychopharmacol Biol Psychiatry"},{"key":"10.1016\/j.yebeh.2007.01.004_bib34","doi-asserted-by":"crossref","first-page":"1598","DOI":"10.1056\/NEJMp048228","article-title":"Antidepressants and pediatric depression: the risk of doing nothing","volume":"351","author":"Brent","year":"2004","journal-title":"N Engl J Med."},{"key":"10.1016\/j.yebeh.2007.01.004_bib35","doi-asserted-by":"crossref","first-page":"461","DOI":"10.1097\/00004583-199405000-00003","article-title":"Rate and predictors of prepubertal bipolarity during follow-up of 6- to 12-year-old depressed children","volume":"33","author":"Geller","year":"1994","journal-title":"J Am Acad Child Adolesc Psychiatry"},{"key":"10.1016\/j.yebeh.2007.01.004_bib36","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1097\/00004583-199301000-00006","article-title":"The course of major depressive disorder in adolescents: 1. Recovery and risk of manic switching in a follow-up study of psychotic and nonpsychotic subtypes","volume":"32","author":"Strober","year":"1993","journal-title":"J Am Acad Child Adolesc Psychiatry"},{"key":"10.1016\/j.yebeh.2007.01.004_bib37","doi-asserted-by":"crossref","first-page":"456","DOI":"10.1046\/j.1399-5618.2003.00073.x","article-title":"Clinical consequences of under-recognized bipolar spectrum disorder","volume":"5","author":"Dunner","year":"2003","journal-title":"Bipolar Disord"},{"key":"10.1016\/j.yebeh.2007.01.004_bib38","doi-asserted-by":"crossref","first-page":"53","DOI":"10.4088\/JCP.v64n0111","article-title":"Screening for bipolar disorder in the community","volume":"64","author":"Hirschfeld","year":"2003","journal-title":"J Clin Psychiatry"},{"key":"10.1016\/j.yebeh.2007.01.004_bib39","doi-asserted-by":"crossref","first-page":"1201","DOI":"10.4088\/JCP.v64n1010","article-title":"Economic consequences of not recognizing bipolar disorder patients: a cross-sectional descriptive analysis","volume":"64","author":"Howard","year":"2003","journal-title":"J Clin Psychiatry"},{"key":"10.1016\/j.yebeh.2007.01.004_bib40","doi-asserted-by":"crossref","first-page":"1119","DOI":"10.2165\/00023210-200418150-00006","article-title":"Antidepressant treatment and risk of suicide attempt by adolescents with major depressive disorder","volume":"18","author":"Valuck","year":"2004","journal-title":"CNS Drugs"},{"key":"10.1016\/j.yebeh.2007.01.004_bib41","doi-asserted-by":"crossref","first-page":"1959","DOI":"10.1016\/S0140-6736(06)68860-0","article-title":"How have the SSRI antidepressants affected suicide risk?","volume":"367","author":"Hall","year":"2006","journal-title":"Lancet"},{"key":"10.1016\/j.yebeh.2007.01.004_bib42","doi-asserted-by":"crossref","first-page":"807","DOI":"10.1001\/jama.292.7.807","article-title":"Fluoxetine, cognitive-behavioural therapy, and their combination for adolescents with depression: Treatment for Adolescents with Depression Study (TADS) randomized controlled trial","volume":"292","author":"March","year":"2004","journal-title":"JAMA"},{"key":"10.1016\/j.yebeh.2007.01.004_bib43","doi-asserted-by":"crossref","first-page":"879","DOI":"10.1136\/bmj.328.7444.879","article-title":"Efficacy and safety of antidepressants for children and adolescents","volume":"328","author":"Jureidini","year":"2004","journal-title":"BMJ"},{"key":"10.1016\/j.yebeh.2007.01.004_bib44","doi-asserted-by":"crossref","first-page":"473","DOI":"10.1038\/sj.npp.1300958","article-title":"ACNP Task Force report on SSRIs and suicidal behavior in youth","volume":"31","author":"Mann","year":"2006","journal-title":"Neuropsychopharmacology"},{"key":"10.1016\/j.yebeh.2007.01.004_bib45","doi-asserted-by":"crossref","first-page":"332","DOI":"10.1001\/archpsyc.63.3.332","article-title":"Suicidality in pediatric patients treated with antidepressant drugs","volume":"63","author":"Hammad","year":"2006","journal-title":"Arch Gen Psychiatry"},{"key":"10.1016\/j.yebeh.2007.01.004_bib46","doi-asserted-by":"crossref","first-page":"1595","DOI":"10.1056\/NEJMp048279","article-title":"A black-box warning for antidepressants in children?","volume":"351","author":"Newman","year":"2004","journal-title":"N Engl J Med"}],"container-title":["Epilepsy &amp; Behavior"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1525505007000121?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1525505007000121?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,4,24]],"date-time":"2019-04-24T17:39:11Z","timestamp":1556127551000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1525505007000121"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007,5]]},"references-count":46,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2007,5]]}},"alternative-id":["S1525505007000121"],"URL":"https:\/\/doi.org\/10.1016\/j.yebeh.2007.01.004","relation":{},"ISSN":["1525-5050"],"issn-type":[{"value":"1525-5050","type":"print"}],"subject":[],"published":{"date-parts":[[2007,5]]}}}