{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,29]],"date-time":"2026-08-29T08:49:57Z","timestamp":1787993397096,"version":"build-2784847793"},"reference-count":44,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2008,2,1]],"date-time":"2008-02-01T00:00:00Z","timestamp":1201824000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2008,2,1]],"date-time":"2008-02-01T00:00:00Z","timestamp":1201824000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2008,2,1]],"date-time":"2008-02-01T00:00:00Z","timestamp":1201824000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2008,2,1]],"date-time":"2008-02-01T00:00:00Z","timestamp":1201824000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2008,2,1]],"date-time":"2008-02-01T00:00:00Z","timestamp":1201824000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2008,2,1]],"date-time":"2008-02-01T00:00:00Z","timestamp":1201824000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2008,2,1]],"date-time":"2008-02-01T00:00:00Z","timestamp":1201824000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/100004330","name":"GlaxoSmithKline","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100004330","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","epilepsybehavior.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Epilepsy &amp; Behavior"],"published-print":{"date-parts":[[2008,2]]},"DOI":"10.1016\/j.yebeh.2007.10.007","type":"journal-article","created":{"date-parts":[[2007,12,5]],"date-time":"2007-12-05T13:14:37Z","timestamp":1196860477000},"page":"298-304","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":46,"title":["Lack of effects of vagus nerve stimulation on drug-resistant epilepsy in eight pediatric patients with autism spectrum disorders: A prospective 2-year follow-up study"],"prefix":"10.1016","volume":"12","author":[{"given":"Susanna","family":"Danielsson","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gerd","family":"Viggedal","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christopher","family":"Gillberg","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ingrid","family":"Olsson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.yebeh.2007.10.007_bib1","unstructured":"Diagnostic and statistical manual of mental disorders. 4th ed. Washington, DC: Am. Psychiatric Assoc.; 1994."},{"key":"10.1016\/j.yebeh.2007.10.007_bib2","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1111\/j.1469-8749.1996.tb15081.x","article-title":"Autism and medical disorders: a review of the literature","volume":"38","author":"Gillberg","year":"1996","journal-title":"Dev Med Child Neurol"},{"key":"10.1016\/j.yebeh.2007.10.007_bib3","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1097\/00004583-199001000-00020","article-title":"Seizure disorders in autism","volume":"29","author":"Volkmar","year":"1990","journal-title":"J Am Acad Child Adolesc Psychiatry"},{"key":"10.1016\/j.yebeh.2007.10.007_bib4","doi-asserted-by":"crossref","first-page":"352","DOI":"10.1016\/S1474-4422(02)00160-6","article-title":"Epilepsy in autism","volume":"1","author":"Tuchman","year":"2002","journal-title":"Lancet Neurol"},{"key":"10.1016\/j.yebeh.2007.10.007_bib5","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1007\/BF02098864","article-title":"Autism in Northern Sweden: a population-based follow-up study: psychopathology","volume":"2","author":"Von-Knorring","year":"1993","journal-title":"Eur Child Adolesc Psychiatry"},{"key":"10.1016\/j.yebeh.2007.10.007_bib6","doi-asserted-by":"crossref","first-page":"351","DOI":"10.1007\/s10803-005-3302-5","article-title":"Autism after adolescence: population-based 13\u201322-year follow-up study of 120 individuals with autism diagnosed in childhood","volume":"35","author":"Billstedt","year":"2005","journal-title":"J Autism Dev Disord"},{"key":"10.1016\/j.yebeh.2007.10.007_bib7","doi-asserted-by":"crossref","first-page":"918","DOI":"10.1111\/j.1528-1167.2005.57504.x","article-title":"Epilepsy in young adults with autism: a prospective population-based follow-up study of 120 individuals diagnosed in childhood","volume":"46","author":"Danielsson","year":"2005","journal-title":"Epilepsia"},{"key":"10.1016\/j.yebeh.2007.10.007_bib8","doi-asserted-by":"crossref","first-page":"S21","DOI":"10.1212\/WNL.59.6_suppl_4.S21","article-title":"Vagus nerve stimulation therapy in patients younger than 18 years","volume":"59","author":"Wheless","year":"2002","journal-title":"Neurology"},{"key":"10.1016\/j.yebeh.2007.10.007_bib9","doi-asserted-by":"crossref","first-page":"S15","DOI":"10.1212\/WNL.59.6_suppl_4.S15","article-title":"Vagus nerve stimulation therapy summary: five years after FDA approval","volume":"59","author":"Schachter","year":"2002","journal-title":"Neurology"},{"key":"10.1016\/j.yebeh.2007.10.007_bib10","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1111\/1469-7610.00006","article-title":"Childhood epilepsy in relation to mental handicap and behavioural disorders","volume":"43","author":"Besag","year":"2002","journal-title":"J Child Psychol Psychiatry"},{"key":"10.1016\/j.yebeh.2007.10.007_bib11","doi-asserted-by":"crossref","first-page":"S2","DOI":"10.1016\/j.yebeh.2003.10.002","article-title":"Psychiatric comorbidity in patients with epilepsy: implications for diagnosis and treatment","volume":"4","author":"Devinsky","year":"2003","journal-title":"Epilepsy Behav"},{"key":"10.1016\/j.yebeh.2007.10.007_bib12","doi-asserted-by":"crossref","first-page":"666","DOI":"10.1017\/S0012162205001362","article-title":"Psychopathology in children with epilepsy before and after temporal lobe resection","volume":"47","author":"McLellan","year":"2005","journal-title":"Dev Med Child Neurol"},{"key":"10.1016\/j.yebeh.2007.10.007_bib13","doi-asserted-by":"crossref","first-page":"809","DOI":"10.1111\/j.1528-1157.1998.tb01173.x","article-title":"Vagus nerve stimulation in 16 children with refractory epilepsy","volume":"39","author":"Lundgren","year":"1998","journal-title":"Epilepsia"},{"key":"10.1016\/j.yebeh.2007.10.007_bib14","doi-asserted-by":"crossref","first-page":"368","DOI":"10.1016\/S0887-8994(01)00319-8","article-title":"Vagus nerve stimulation in pediatric epilepsy: a review","volume":"25","author":"Valencia","year":"2001","journal-title":"Pediatr Neurol"},{"key":"10.1016\/j.yebeh.2007.10.007_bib15","doi-asserted-by":"crossref","first-page":"343","DOI":"10.1006\/ebeh.2001.0218","article-title":"Effects of 6 months of treatment with vagus nerve stimulation on behavior in children with Lennox\u2013Gastaut syndrome in an open clinical and nonrandomized study","volume":"2","author":"Aldenkamp","year":"2001","journal-title":"Epilepsy Behav"},{"key":"10.1016\/j.yebeh.2007.10.007_bib16","doi-asserted-by":"crossref","first-page":"504","DOI":"10.1016\/j.seizure.2005.08.007","article-title":"Vagus nerve stimulation in 15 children with therapy resistant epilepsy; its impact on cognition, quality of life, behaviour and mood","volume":"14","author":"Hallb\u00f6\u00f6k","year":"2005","journal-title":"Seizure"},{"key":"10.1016\/j.yebeh.2007.10.007_bib17","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1016\/S0887-8994(00)00170-3","article-title":"Left vagal nerve stimulation in six patients with hypothalamic hamartomas","volume":"23","author":"Murphy","year":"2000","journal-title":"Pediatr Neurol"},{"key":"10.1016\/j.yebeh.2007.10.007_bib18","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1016\/S0887-8994(01)00312-5","article-title":"Vagal nerve stimulation in tuberous sclerosis complex patients","volume":"25","author":"Parain","year":"2001","journal-title":"Pediatr Neurol"},{"key":"10.1016\/j.yebeh.2007.10.007_bib19","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1034\/j.1600-0404.2002.00129.x","article-title":"VNS therapy in clinical practice in children with refractory epilepsy","volume":"105","author":"Nagarajan","year":"2002","journal-title":"Acta Neurol Scand"},{"key":"10.1016\/j.yebeh.2007.10.007_bib20","doi-asserted-by":"crossref","first-page":"483","DOI":"10.1016\/j.seizure.2006.06.001","article-title":"Vagus nerve stimulation: clinical experience in drug-resistant pediatric epileptic patients","volume":"15","author":"Rychlicki","year":"2006","journal-title":"Seizure"},{"key":"10.1016\/j.yebeh.2007.10.007_bib21","doi-asserted-by":"crossref","first-page":"344","DOI":"10.1016\/j.yebeh.2007.01.001","article-title":"Effects of vagus nerve stimulation in a patient with temporal lobe epilepsy and Asperger syndrome: case report and review of the literature","volume":"10","author":"Warwick","year":"2007","journal-title":"Epilepsy Behav"},{"key":"10.1016\/j.yebeh.2007.10.007_bib22","doi-asserted-by":"crossref","first-page":"286","DOI":"10.1016\/S1525-5050(03)00080-5","article-title":"The effects of vagus nerve stimulation therapy on patients with intractable seizures and either Landau\u2013Kleffner syndrome or autism","volume":"4","author":"Park","year":"2003","journal-title":"Epilepsy Behav"},{"key":"10.1016\/j.yebeh.2007.10.007_bib23","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1023\/A:1005592401947","article-title":"The Autism Diagnostic Observation Schedule\u2014Generic: a standard measure of social and communication deficits associated with the spectrum of autism","volume":"30","author":"Lord","year":"2000","journal-title":"J Autism Dev Disord"},{"key":"10.1016\/j.yebeh.2007.10.007_bib24","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1111\/1469-7610.00023","article-title":"The Diagnostic Interview for Social and Communication Disorders: background, inter-rater reliability and clinical use","volume":"43","author":"Wing","year":"2002","journal-title":"J Child Psychol Psychiatry"},{"key":"10.1016\/j.yebeh.2007.10.007_bib25","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1111\/j.1469-7610.1980.tb01797.x","article-title":"Behavior checklist for identifying severely handicapped individuals with high levels of autistic behavior","volume":"21","author":"Krug","year":"1980","journal-title":"J Child Psychol Psychiatry"},{"key":"10.1016\/j.yebeh.2007.10.007_bib26","unstructured":"Diagnostic and statistical manual of mental disorders. 4th ed. Text revision. Washington, DC: Am. Psychiatric Assoc.; 2000."},{"key":"10.1016\/j.yebeh.2007.10.007_bib27","doi-asserted-by":"crossref","first-page":"530","DOI":"10.4088\/JCP.v62n07a05","article-title":"An open trial of divalproex sodium in autism spectrum disorders","volume":"62","author":"Hollander","year":"2001","journal-title":"J Clin Psychiatry"},{"key":"10.1016\/j.yebeh.2007.10.007_bib28","unstructured":"Griffiths R. The abilities of young children: a comprehensive system of mental measurement for the first eight years of life. London: Child Development Research Centre; 1970. [Griffiths R. Griffiths utvecklingsskalor. H\u00e4gersten: Psykologif\u00f6rlaget; 1980.]."},{"key":"10.1016\/j.yebeh.2007.10.007_bib29","series-title":"Wechsler Intelligence Scale for Children","author":"Wechsler","year":"1999"},{"key":"10.1016\/j.yebeh.2007.10.007_bib30","series-title":"Wechsler Adult Intelligence Scale","author":"Wechsler","year":"2003"},{"key":"10.1016\/j.yebeh.2007.10.007_bib31","series-title":"The ICD-10 Classification of Mental and Behavioural Disorders: diagnostic criteria for research","author":"World Health Organization","year":"1993"},{"key":"10.1016\/j.yebeh.2007.10.007_bib32","doi-asserted-by":"crossref","first-page":"560","DOI":"10.1001\/archpedi.157.6.560","article-title":"Vagal nerve stimulation in refractory epilepsy: the first 100 patients receiving vagal nerve stimulation at a pediatric epilepsy center","volume":"157","author":"Murphy","year":"2003","journal-title":"Arch Pediatr Adolesc Med"},{"key":"10.1016\/j.yebeh.2007.10.007_bib33","doi-asserted-by":"crossref","first-page":"491","DOI":"10.1016\/j.seizure.2006.06.002","article-title":"Long-term results with vagus nerve stimulation in children with pharmacoresistant epilepsy","volume":"15","author":"Alexopoulos","year":"2006","journal-title":"Seizure"},{"key":"10.1016\/j.yebeh.2007.10.007_bib34","doi-asserted-by":"crossref","first-page":"469","DOI":"10.1111\/j.1469-8749.2000.tb00356.x","article-title":"Vagus nerve stimulation for intractable epilepsy in children","volume":"42","author":"Labar","year":"2000","journal-title":"Dev Med Child Neurol"},{"key":"10.1016\/j.yebeh.2007.10.007_bib35","doi-asserted-by":"crossref","first-page":"1353","DOI":"10.1097\/00006123-200012000-00016","article-title":"Efficacy of vagal nerve stimulation in children with medically refractory epilepsy","volume":"47","author":"Patwardhan","year":"2000","journal-title":"Neurosurgery"},{"key":"10.1016\/j.yebeh.2007.10.007_bib36","doi-asserted-by":"crossref","first-page":"475","DOI":"10.1016\/S1525-5050(02)00517-6","article-title":"Long-term effects of 24-month treatment with vagus nerve stimulation on behaviour in children with Lennox\u2013Gastaut syndrome","volume":"3","author":"Aldenkamp","year":"2002","journal-title":"Epilepsy Behav"},{"key":"10.1016\/j.yebeh.2007.10.007_bib37","doi-asserted-by":"crossref","first-page":"778","DOI":"10.1542\/peds.103.4.778","article-title":"Vagal nerve stimulation in epileptic encephalopathies","volume":"103","author":"Parker","year":"1999","journal-title":"Pediatrics"},{"key":"10.1016\/j.yebeh.2007.10.007_bib38","doi-asserted-by":"crossref","first-page":"1148","DOI":"10.1046\/j.1528-1157.2001.23900.x","article-title":"Vagus nerve stimulation in children with refractory seizures associated with Lennox\u2013Gastaut syndrome","volume":"42","author":"Frost","year":"2001","journal-title":"Epilepsia"},{"key":"10.1016\/j.yebeh.2007.10.007_bib39","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1007\/s00381-001-0548-x","article-title":"Intermittent vagal nerve stimulation in paediatric patients: 1-year follow-up","volume":"18","author":"Zamponi","year":"2002","journal-title":"Childs Nerv Syst"},{"key":"10.1016\/j.yebeh.2007.10.007_bib40","doi-asserted-by":"crossref","first-page":"843","DOI":"10.1177\/08830738010160111101","article-title":"Vagus nerve stimulation therapy in pediatric patients with refractory epilepsy: retrospective study","volume":"16","author":"Helmers","year":"2001","journal-title":"J Child Neurol"},{"key":"10.1016\/j.yebeh.2007.10.007_bib41","doi-asserted-by":"crossref","first-page":"597","DOI":"10.1016\/j.yebeh.2003.09.013","article-title":"When did neurologists and psychiatrists stop talking to each other?","volume":"4","author":"Kanner","year":"2003","journal-title":"Epilepsy Behav"},{"key":"10.1016\/j.yebeh.2007.10.007_bib42","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1016\/j.seizure.2004.02.003","article-title":"Vagus nerve stimulation in patients with catastrophic childhood epilepsy, a 2-year follow-up study","volume":"14","author":"Majoie","year":"2005","journal-title":"Seizure"},{"key":"10.1016\/j.yebeh.2007.10.007_bib43","doi-asserted-by":"crossref","first-page":"561","DOI":"10.1111\/j.0013-9580.2005.03504.x","article-title":"Cognitive function in preschool children after epilepsy surgery: Rationale for early intervention","volume":"46","author":"Freitag","year":"2005","journal-title":"Epilepsia"},{"key":"10.1016\/j.yebeh.2007.10.007_bib44","doi-asserted-by":"crossref","first-page":"94","DOI":"10.1038\/4600","article-title":"Enhanced recognition memory following vagus nerve stimulation in human subjects","volume":"2","author":"Clark","year":"1999","journal-title":"Nat Neurosci"}],"container-title":["Epilepsy &amp; Behavior"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1525505007003605?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1525505007003605?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,26]],"date-time":"2025-10-26T18:19:42Z","timestamp":1761502782000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1525505007003605"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,2]]},"references-count":44,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2008,2]]}},"alternative-id":["S1525505007003605"],"URL":"https:\/\/doi.org\/10.1016\/j.yebeh.2007.10.007","relation":{},"ISSN":["1525-5050"],"issn-type":[{"value":"1525-5050","type":"print"}],"subject":[],"published":{"date-parts":[[2008,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Lack of effects of vagus nerve stimulation on drug-resistant epilepsy in eight pediatric patients with autism spectrum disorders: A prospective 2-year follow-up study","name":"articletitle","label":"Article Title"},{"value":"Epilepsy & Behavior","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.yebeh.2007.10.007","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2007 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}