{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,13]],"date-time":"2026-08-13T15:06:42Z","timestamp":1786633602357,"version":"build-2736575974"},"reference-count":28,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2011,6,1]],"date-time":"2011-06-01T00:00:00Z","timestamp":1306886400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2011,6,1]],"date-time":"2011-06-01T00:00:00Z","timestamp":1306886400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2011,6,1]],"date-time":"2011-06-01T00:00:00Z","timestamp":1306886400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2011,6,1]],"date-time":"2011-06-01T00:00:00Z","timestamp":1306886400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2011,6,1]],"date-time":"2011-06-01T00:00:00Z","timestamp":1306886400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2011,6,1]],"date-time":"2011-06-01T00:00:00Z","timestamp":1306886400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2011,6,1]],"date-time":"2011-06-01T00:00:00Z","timestamp":1306886400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","epilepsybehavior.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Epilepsy & Behavior"],"published-print":{"date-parts":[[2011,6]]},"DOI":"10.1016\/j.yebeh.2011.03.015","type":"journal-article","created":{"date-parts":[[2011,4,22]],"date-time":"2011-04-22T19:33:24Z","timestamp":1303500804000},"page":"173-176","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":19,"title":["Lamotrigine improves aggression in patients with temporal lobe epilepsy"],"prefix":"10.1016","volume":"21","author":[{"given":"Hiroko","family":"Kato","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Naofumi","family":"Fukatsu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takahiro","family":"Noguchi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tomohiro","family":"Oshima","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yukari","family":"Tadokoro","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kousuke","family":"Kanemoto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"Pt. 2","key":"10.1016\/j.yebeh.2011.03.015_bb0005","doi-asserted-by":"crossref","first-page":"234","DOI":"10.1093\/brain\/123.2.234","article-title":"Affective aggression in patients with temporal lobe epilepsy: a quantitative MRI study of the amygdala","volume":"123","author":"Van Elst","year":"2000","journal-title":"Brain"},{"key":"10.1016\/j.yebeh.2011.03.015_bb0010","doi-asserted-by":"crossref","first-page":"324","DOI":"10.1097\/00005053-197505000-00002","article-title":"Temporal lobe epilepsy and aggression","volume":"160","author":"Kligman","year":"1975","journal-title":"J Nerv Ment Dis"},{"key":"10.1016\/j.yebeh.2011.03.015_bb0015","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1001\/archneur.1974.00490310003001","article-title":"Brain research and violent behavior: a summary and evaluation of the status of biomedical research on brain and aggressive violent behavior\u2014clinical studies","volume":"30","author":"Goldstein","year":"1974","journal-title":"Arch Neurol"},{"key":"10.1016\/j.yebeh.2011.03.015_bb0020","doi-asserted-by":"crossref","first-page":"354","DOI":"10.1097\/00005053-198306000-00005","article-title":"An empirical analysis of specific syndromes of violent behavior","volume":"171","author":"Mungas","year":"1983","journal-title":"J Nerv Ment Dis"},{"key":"10.1016\/j.yebeh.2011.03.015_bb0025","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1097\/00004583-199703000-00008","article-title":"Subtypes of aggression and their relevance to child psychiatry [review]","volume":"36","author":"Vitiello","year":"1997","journal-title":"J Am Acad Child Adolesc Psychiatry"},{"key":"10.1016\/j.yebeh.2011.03.015_bb0030","doi-asserted-by":"crossref","first-page":"383","DOI":"10.1007\/s11940-009-0043-3","article-title":"Pharmacologic treatment of impulsive aggression with antiepileptic drugs","volume":"11","author":"Stanford","year":"2009","journal-title":"Curr Treat Options Neurol"},{"key":"10.1016\/j.yebeh.2011.03.015_bb0035","doi-asserted-by":"crossref","first-page":"452","DOI":"10.1037\/0022-3514.63.3.452","article-title":"The Aggression Questionnaire","volume":"63","author":"Buss","year":"1992","journal-title":"J Pers Soc Psychol"},{"key":"10.1016\/j.yebeh.2011.03.015_bb0040","doi-asserted-by":"crossref","first-page":"384","DOI":"10.4992\/jjpsy.70.384","article-title":"Development of the Japanese version of the Buss\u2013Perry Aggression Questionnaire (BAQ)","volume":"70","author":"Ando","year":"1999","journal-title":"Jpn J Psychol"},{"key":"10.1016\/j.yebeh.2011.03.015_bb0045","doi-asserted-by":"crossref","first-page":"853","DOI":"10.1016\/S0005-7967(00)00057-7","article-title":"Psychometric evaluation on the Japanese adaptation of the Aggression Questionnaire","volume":"39","author":"Nakano","year":"2001","journal-title":"Behav Res Ther"},{"key":"10.1016\/j.yebeh.2011.03.015_bb0050","doi-asserted-by":"crossref","first-page":"148","DOI":"10.1016\/j.yebeh.2006.09.008","article-title":"Effect of lamotrigine on depressive symptoms in adult patients with epilepsy","volume":"10","author":"Ettinger","year":"2007","journal-title":"Epilepsy Behav"},{"key":"10.1016\/j.yebeh.2011.03.015_bb0055","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1016\/j.yebeh.2006.11.003","article-title":"Lamotrigine in patients with epilepsy and comorbid depressive symptoms","volume":"10","author":"Fakhoury","year":"2007","journal-title":"Epilepsy Behav"},{"key":"10.1016\/j.yebeh.2011.03.015_bb0060","doi-asserted-by":"crossref","first-page":"955","DOI":"10.2165\/0002512-200825110-00006","article-title":"Effects of lamotrigine on mood in older adults with epilepsy and co-morbid depressive symptoms","volume":"25","author":"Fakhoury","year":"2008","journal-title":"Drugs Aging"},{"key":"10.1016\/j.yebeh.2011.03.015_bb0065","doi-asserted-by":"crossref","first-page":"702","DOI":"10.1016\/j.yebeh.2004.07.005","article-title":"Improved mood states with lamotrigine in patients with epilepsy","volume":"5","author":"Cramer","year":"2004","journal-title":"Epilepsy Behav"},{"key":"10.1016\/j.yebeh.2011.03.015_bb0070","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1006\/ebeh.2000.0143","article-title":"Lamotrigine monotherapy improves depressive symptoms in epilepsy: a double-blind comparison with valproate","volume":"2","author":"Edwards","year":"2001","journal-title":"Epilepsy Behav"},{"key":"10.1016\/j.yebeh.2011.03.015_bb0075","doi-asserted-by":"crossref","first-page":"510","DOI":"10.1016\/S1525-5050(02)00528-0","article-title":"Improvement in depression associated with partial epilepsy in patients treated with lamotrigine","volume":"3","author":"Kalogjera-Sackellares","year":"2002","journal-title":"Epilepsy Behav"},{"key":"10.1016\/j.yebeh.2011.03.015_bb0080","doi-asserted-by":"crossref","first-page":"434","DOI":"10.1111\/j.1528-1167.2008.01792.x","article-title":"Effects of lamotrigine compared with levetiracetam on anger, hostility, and total mood in patients with partial epilepsy","volume":"50","author":"Labiner","year":"2009","journal-title":"Epilepsia"},{"key":"10.1016\/j.yebeh.2011.03.015_bb0085","doi-asserted-by":"crossref","first-page":"343","DOI":"10.1037\/h0046900","article-title":"An inventory for assessing different kinds of hostility","volume":"21","author":"Buss","year":"1957","journal-title":"J Consult Psychol"},{"key":"10.1016\/j.yebeh.2011.03.015_bb0090","doi-asserted-by":"crossref","first-page":"445","DOI":"10.1176\/jnp.7.4.445","article-title":"Psychiatric morbidity in seizure patients on a neurodiagnostic monitoring unit","volume":"7","author":"Blumer","year":"1995","journal-title":"J Neuropsychiatry Clin Neurosci"},{"key":"10.1016\/j.yebeh.2011.03.015_bb0095","doi-asserted-by":"crossref","first-page":"162","DOI":"10.1016\/j.yebeh.2010.06.018","article-title":"Violence and postictal psychosis: a comparison of postictal psychosis, interictal psychosis, and postictal confusion","volume":"19","author":"Kanemoto","year":"2010","journal-title":"Epilepsy Behav"},{"key":"10.1016\/j.yebeh.2011.03.015_bb0100","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1006\/ebeh.2000.0030","article-title":"Depression in epilepsy: a common but often unrecognized comorbid malady","volume":"1","author":"Kanner","year":"2000","journal-title":"Epilepsy Behav"},{"key":"10.1016\/j.yebeh.2011.03.015_bb0105","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1016\/j.yebeh.2009.06.009","article-title":"Amygdala volume loss in patients with dysphoric disorder of epilepsy","volume":"16","author":"Van Elst","year":"2009","journal-title":"Epilepsy Behav"},{"key":"10.1016\/j.yebeh.2011.03.015_bb0110","doi-asserted-by":"crossref","first-page":"1067","DOI":"10.1111\/j.1528-1167.2008.01883.x","article-title":"Temporal lobe epilepsy, depression, and hippocampal volume","volume":"50","author":"Shamim","year":"2009","journal-title":"Epilepsia"},{"key":"10.1016\/j.yebeh.2011.03.015_bb0115","doi-asserted-by":"crossref","first-page":"287","DOI":"10.1177\/0269881105051540","article-title":"Lamotrigine treatment of aggression in female borderline-patients: a randomized, double-blind, placebo-controlled study","volume":"19","author":"Tritt","year":"2005","journal-title":"J Psychopharmacol"},{"key":"10.1016\/j.yebeh.2011.03.015_bb0120","doi-asserted-by":"crossref","first-page":"1645","DOI":"10.1176\/ajp.155.11.1626ai","article-title":"Treatment of borderline personality disorder","volume":"155","author":"Shapiro","year":"1998","journal-title":"Am J Psychiatry"},{"key":"10.1016\/j.yebeh.2011.03.015_bb0125","doi-asserted-by":"crossref","first-page":"333","DOI":"10.1016\/S0165-0327(99)00007-5","article-title":"Lamotrigine as a promising approach to borderline personality: an open case series without concurrent DSM-IV major mood disorder","volume":"51","author":"Pinto","year":"1998","journal-title":"J Affect Disord"},{"key":"10.1016\/j.yebeh.2011.03.015_bb0130","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1016\/S0165-0327(02)00358-0","article-title":"Borderline personality disorder in patients with bipolar disorder and response to lamotrigine","volume":"79","author":"Preston","year":"2004","journal-title":"J Affect Disord"},{"key":"10.1016\/j.yebeh.2011.03.015_bb0135","doi-asserted-by":"crossref","first-page":"484","DOI":"10.1097\/01.jcp.0000088915.02635.e8","article-title":"Potential mechanisms of action of lamotrigine in the treatment of bipolar disorders","volume":"23","author":"Ketter","year":"2003","journal-title":"J Clin Psychopharmacol"},{"key":"10.1016\/j.yebeh.2011.03.015_bb0140","doi-asserted-by":"crossref","first-page":"2134","DOI":"10.1176\/appi.ajp.160.12.2134","article-title":"Agitated depression in bipolar I disorder: prevalence, phenomenology, and outcome","volume":"160","author":"Maj","year":"2003","journal-title":"Am J Psychiatry"}],"container-title":["Epilepsy & Behavior"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1525505011001193?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1525505011001193?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,26]],"date-time":"2025-10-26T18:23:04Z","timestamp":1761502984000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1525505011001193"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,6]]},"references-count":28,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2011,6]]}},"alternative-id":["S1525505011001193"],"URL":"https:\/\/doi.org\/10.1016\/j.yebeh.2011.03.015","relation":{},"ISSN":["1525-5050"],"issn-type":[{"value":"1525-5050","type":"print"}],"subject":[],"published":{"date-parts":[[2011,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Lamotrigine improves aggression in patients with temporal lobe epilepsy","name":"articletitle","label":"Article Title"},{"value":"Epilepsy & Behavior","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.yebeh.2011.03.015","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2011 Published by Elsevier Inc.","name":"copyright","label":"Copyright"}]}}