{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,26]],"date-time":"2025-10-26T21:09:57Z","timestamp":1761512997738,"version":"build-2065373602"},"reference-count":97,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2011,8,1]],"date-time":"2011-08-01T00:00:00Z","timestamp":1312156800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2011,8,1]],"date-time":"2011-08-01T00:00:00Z","timestamp":1312156800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/100011110","name":"UCB","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100011110","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","epilepsybehavior.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Epilepsy &amp; Behavior"],"published-print":{"date-parts":[[2011,8]]},"DOI":"10.1016\/j.yebeh.2011.04.056","type":"journal-article","created":{"date-parts":[[2011,6,26]],"date-time":"2011-06-26T00:06:16Z","timestamp":1309046776000},"page":"344-351","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":43,"title":["Sudden unexpected death in epilepsy"],"prefix":"10.1016","volume":"21","author":[{"given":"Susan","family":"Duncan","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Martin J.","family":"Brodie","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"Suppl. 11","key":"10.1016\/j.yebeh.2011.04.056_bb0005","first-page":"s6","article-title":"Sudden unexpected death in epilepsy: terminology and definitions","volume":"38","author":"Nashef","year":"1997","journal-title":"Epilepsia"},{"issue":"Suppl. 11","key":"10.1016\/j.yebeh.2011.04.056_bb0010","first-page":"s9","article-title":"United States perspective on definitions and classifications","volume":"38","author":"Annegers","year":"1997","journal-title":"Epilepsia"},{"key":"10.1016\/j.yebeh.2011.04.056_bb0015","doi-asserted-by":"crossref","first-page":"1021","DOI":"10.1016\/S1474-4422(08)70202-3","article-title":"Sudden unexpected death in epilepsy: current knowledge and future directions","volume":"7","author":"Tomson","year":"2008","journal-title":"Lancet Neurol"},{"key":"10.1016\/j.yebeh.2011.04.056_bb0020","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1016\/j.eplepsyres.2005.05.004","article-title":"Sudden unexpected death in epilepsy: evidence\u2013based analysis of incidence and risk factors","volume":"65","author":"Tellez-Zenteno","year":"2005","journal-title":"Epilepsy Res"},{"key":"10.1016\/j.yebeh.2011.04.056_bb0025","doi-asserted-by":"crossref","first-page":"1270","DOI":"10.1212\/WNL.51.5.1270","article-title":"Population-based study of the incidence of sudden unexplained death in epilepsy","volume":"51","author":"Ficker","year":"1998","journal-title":"Neurology"},{"key":"10.1016\/j.yebeh.2011.04.056_bb0030","doi-asserted-by":"crossref","first-page":"84","DOI":"10.1111\/j.1528-1157.1984.tb04159.x","article-title":"Sudden unexpected death associated with seizures: analysis of 66 cases","volume":"25","author":"Leestma","year":"1984","journal-title":"Epilepsia"},{"key":"10.1016\/j.yebeh.2011.04.056_bb0035","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1002\/ana.410260203","article-title":"A prospective study on sudden unexpected death in epilepsy","volume":"26","author":"Leestma","year":"1989","journal-title":"Ann Neurol"},{"key":"10.1016\/j.yebeh.2011.04.056_bb0040","doi-asserted-by":"crossref","first-page":"456","DOI":"10.1016\/S1059-1311(02)00352-7","article-title":"Risk factors of sudden unexpected death in epilepsy: a controlled prospective study based on coroners cases","volume":"12","author":"Opeskin","year":"2003","journal-title":"Seizure"},{"key":"10.1016\/j.yebeh.2011.04.056_bb0045","doi-asserted-by":"crossref","first-page":"336","DOI":"10.1002\/ana.70","article-title":"Mortality in epilepsy in the first 11\u201314years after diagnosis: multivariate analysis of a long-term prospective population based cohort","volume":"49","author":"Lhattoo","year":"2001","journal-title":"Ann Neurol"},{"key":"10.1016\/j.yebeh.2011.04.056_bb0050","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1016\/j.eplepsyres.2005.10.004","article-title":"Coroner and medical examiner documentation of sudden unexplained death in epilepsy","volume":"68","author":"Schraeder","year":"2006","journal-title":"Epilepsy Res"},{"key":"10.1016\/j.yebeh.2011.04.056_bb0055","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1002\/pds.2630010203","article-title":"Sudden unexpected death in young persons with primary epilepsy","volume":"1","author":"Jick","year":"1992","journal-title":"Pharmacoepidemiol Drug Saf"},{"key":"10.1016\/j.yebeh.2011.04.056_bb0060","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1111\/j.1528-1157.1995.tb01661.x","article-title":"Cohort study of incidence of sudden unexplained death in persons with seizure disorder treated with anti-epileptic drugs in Saskatchewan, Canada","volume":"36","author":"Tennis","year":"1995","journal-title":"Epilepsia"},{"key":"10.1016\/j.yebeh.2011.04.056_bb0065","doi-asserted-by":"crossref","first-page":"287","DOI":"10.1016\/S1059-1311(05)80142-6","article-title":"Sudden unexpected death in epilepsy: a local audit","volume":"2","author":"Timmings","year":"1993","journal-title":"Seizure"},{"key":"10.1016\/j.yebeh.2011.04.056_bb0070","doi-asserted-by":"crossref","first-page":"1187","DOI":"10.1111\/j.1528-1157.1995.tb01061.x","article-title":"Mortality in patients with epilepsy: a study of incidence in a young cohort with epilepsy and learning difficulties","volume":"36","author":"Nashef","year":"1995","journal-title":"Epilepsia"},{"key":"10.1016\/j.yebeh.2011.04.056_bb0075","doi-asserted-by":"crossref","first-page":"462","DOI":"10.1136\/jnnp.58.4.462","article-title":"Incidence of sudden unexpected death in an adult outpatient cohort with epilepsy at a tertiary referral centre","volume":"58","author":"Nashef","year":"1995","journal-title":"J Neurol Neurosurg Psychiatry"},{"key":"10.1016\/j.yebeh.2011.04.056_bb0080","doi-asserted-by":"crossref","first-page":"481","DOI":"10.1016\/S1474-4422(06)70448-3","article-title":"Mortality in adults with newly diagnosed and chronic epilepsy: a retrospective comparative study","volume":"5","author":"Mohanraj","year":"2006","journal-title":"Lancet Neurol"},{"issue":"Suppl. 11","key":"10.1016\/j.yebeh.2011.04.056_bb0085","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1111\/j.1528-1167.2005.00410.x","article-title":"Mortality after epilepsy surgery","volume":"46","author":"Sperling","year":"2005","journal-title":"Epilepsia"},{"key":"10.1016\/j.yebeh.2011.04.056_bb0090","doi-asserted-by":"crossref","first-page":"573","DOI":"10.1046\/j.1528-1157.2003.03302.x","article-title":"Mortality in a population based cohort of epilepsy surgery patients","volume":"44","author":"Nilsson","year":"2003","journal-title":"Epilepsia"},{"key":"10.1016\/j.yebeh.2011.04.056_bb0095","doi-asserted-by":"crossref","first-page":"1276","DOI":"10.1212\/WNL.53.6.1276","article-title":"A study of mortality after temporal lobe epilepsy surgery","volume":"53","author":"Hennessy","year":"1999","journal-title":"Neurology"},{"key":"10.1016\/j.yebeh.2011.04.056_bb0100","doi-asserted-by":"crossref","first-page":"1445","DOI":"10.1016\/S0140-6736(95)92470-1","article-title":"Outcomes in 248 patients who had diagnostic evaluations for epilepsy surgery","volume":"346","author":"Vickrey","year":"1995","journal-title":"Lancet"},{"key":"10.1016\/j.yebeh.2011.04.056_bb0105","doi-asserted-by":"crossref","first-page":"888","DOI":"10.1016\/S0140-6736(98)05114-9","article-title":"Risk factors for sudden unexpected death in epilepsy","volume":"353","author":"Nilsson","year":"1999","journal-title":"Lancet"},{"key":"10.1016\/j.yebeh.2011.04.056_bb0110","doi-asserted-by":"crossref","first-page":"519","DOI":"10.1212\/WNL.56.4.519","article-title":"Incidence and risk factors in sudden unexpected death in epilepsy: a prospective cohort study","volume":"56","author":"Walczak","year":"2001","journal-title":"Neurology"},{"key":"10.1016\/j.yebeh.2011.04.056_bb0115","doi-asserted-by":"crossref","first-page":"1131","DOI":"10.1212\/01.WNL.0000156352.61328.CB","article-title":"Case control study of SUDEP","volume":"64","author":"Langan","year":"2005","journal-title":"Neurology"},{"key":"10.1016\/j.yebeh.2011.04.056_bb0120","doi-asserted-by":"crossref","first-page":"138","DOI":"10.1016\/j.yebeh.2006.11.010","article-title":"Sudden unexpected death in epilepsy: a search for risk factors","volume":"10","author":"Hitiris","year":"2007","journal-title":"Epilepsy Behav"},{"key":"10.1016\/j.yebeh.2011.04.056_bb0125","doi-asserted-by":"crossref","unstructured":"Hesdorffer DC, Tomson T, Benn E, et al. Combined analysis for risk factors in SUDEP. Epilepsia. Published, online 28 January 2011.","DOI":"10.1111\/j.1528-1167.2010.02952.x"},{"key":"10.1016\/j.yebeh.2011.04.056_bb0130","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1136\/jnnp.64.3.349","article-title":"Circumstances of death in sudden death in epilepsy: interviews of bereaved relatives","volume":"64","author":"Nashef","year":"1998","journal-title":"J Neurol Neurosurg Psychiatry"},{"key":"10.1016\/j.yebeh.2011.04.056_bb0135","doi-asserted-by":"crossref","first-page":"481","DOI":"10.1136\/jnnp.2005.067777","article-title":"Variability of anti-epileptic medication taking behaviour in sudden unexplained death in epilepsy: hair analysis at autopsy","volume":"77","author":"Williams","year":"2006","journal-title":"J Neurol Neurosurg Psychiatry"},{"key":"10.1016\/j.yebeh.2011.04.056_bb0140","doi-asserted-by":"crossref","first-page":"1795","DOI":"10.1111\/j.1528-1157.1999.tb01600.x","article-title":"Comparison of antiepileptic drug levels in sudden unexpected deaths in epilepsy with deaths from other causes","volume":"40","author":"Opeskin","year":"1999","journal-title":"Epilepsia"},{"key":"10.1016\/j.yebeh.2011.04.056_bb0145","doi-asserted-by":"crossref","first-page":"598","DOI":"10.1520\/JFS16186J","article-title":"Comparison of anti-epileptic drug levels in different cases of sudden death","volume":"43","author":"Davis","year":"1998","journal-title":"J Forens Sci"},{"key":"10.1016\/j.yebeh.2011.04.056_bb0150","doi-asserted-by":"crossref","first-page":"439","DOI":"10.1136\/jnnp.67.4.439","article-title":"Sudden expected death in epilepsy (SUDEP): a clinical perspective and search for risk factors","volume":"67","author":"Kloster","year":"1999","journal-title":"J Neurol Neurosurg Psychiatry"},{"key":"10.1016\/j.yebeh.2011.04.056_bb0155","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1111\/j.1528-1157.1997.tb01076.x","article-title":"Sudden unexplained death in epilepsy: observations from a large clinical development program","volume":"38","author":"Leestma","year":"1997","journal-title":"Epilepsia"},{"key":"10.1016\/j.yebeh.2011.04.056_bb0160","doi-asserted-by":"crossref","first-page":"338","DOI":"10.1016\/S1525-5050(02)00037-9","article-title":"The relationship between poor medication compliance and seizures","volume":"3","author":"Cramer","year":"2002","journal-title":"Epilepsy Behav"},{"key":"10.1016\/j.yebeh.2011.04.056_bb0165","doi-asserted-by":"crossref","first-page":"117","DOI":"10.2147\/nedt.2007.3.1.117","article-title":"Managing patient adherence and quality of life in epilepsy","volume":"3","author":"Eatock","year":"2007","journal-title":"Neuropsychiatr Dis Treat"},{"key":"10.1016\/j.yebeh.2011.04.056_bb0170","doi-asserted-by":"crossref","first-page":"1572","DOI":"10.1212\/01.wnl.0000319693.10338.b9","article-title":"Nonadherence to antiepileptic drugs and increased mortality: findings from the RANSOM study","volume":"71","author":"Faught","year":"2008","journal-title":"Neurology"},{"key":"10.1016\/j.yebeh.2011.04.056_bb0175","doi-asserted-by":"crossref","first-page":"194","DOI":"10.1001\/archneur.1986.00520020080028","article-title":"Sudden unexpected death of epileptic patient due to cardiac arrhythmia","volume":"43","author":"Dasheiff","year":"1986","journal-title":"Arch Neurol"},{"issue":"Suppl. 11","key":"10.1016\/j.yebeh.2011.04.056_bb0180","first-page":"S52","article-title":"Sudden unexplained death in epilepsy: an intracranially monitored case","volume":"38","author":"Bird","year":"1997","journal-title":"Epilepsia"},{"key":"10.1016\/j.yebeh.2011.04.056_bb0185","doi-asserted-by":"crossref","first-page":"1828","DOI":"10.1111\/j.1528-1157.1999.tb01606.x","article-title":"Partial seizures manifesting as apnoea only in an adult","volume":"40","author":"Lee","year":"1999","journal-title":"Epilepsia"},{"key":"10.1016\/j.yebeh.2011.04.056_bb0190","doi-asserted-by":"crossref","first-page":"1395","DOI":"10.1136\/jnnp.2006.088492","article-title":"Sudden death in epilepsy recorded on ambulatory EEG","volume":"78","author":"Mclean","year":"2007","journal-title":"J Neurol Neurosurg Psychiatry"},{"key":"10.1016\/j.yebeh.2011.04.056_bb0195","doi-asserted-by":"crossref","first-page":"2344","DOI":"10.1111\/j.1528-1167.2010.02719.x","article-title":"SUDEP, suspected positional airway obstruction, and hypoventilation in postictal coma","volume":"51","author":"Tao","year":"2010","journal-title":"Epilepsia"},{"key":"10.1016\/j.yebeh.2011.04.056_bb0200","doi-asserted-by":"crossref","first-page":"1494","DOI":"10.1111\/j.1528-1157.2000.tb00128.x","article-title":"Postictal central apnoea as a cause of SUDEP: evidence from near-SUDEP incident","volume":"41","author":"So","year":"2000","journal-title":"Epilepsia"},{"key":"10.1016\/j.yebeh.2011.04.056_bb0205","first-page":"339","article-title":"Syncope anoxo-ischaemique par dyspnee obstructive au cours d'un crise partielle complexe temporal droite","volume":"8","author":"Thomas","year":"1996","journal-title":"Epilepsies"},{"key":"10.1016\/j.yebeh.2011.04.056_bb0210","doi-asserted-by":"crossref","first-page":"492","DOI":"10.1038\/nrneurol.2009.118","article-title":"Sudden unexpected death in epilepsy: risk factors and potential pathomechanisms","volume":"5","author":"Sturges","year":"2009","journal-title":"Nat Rev Neurol"},{"key":"10.1016\/j.yebeh.2011.04.056_bb0215","doi-asserted-by":"crossref","first-page":"1051","DOI":"10.1016\/S0140-6736(86)91328-0","article-title":"Electrocardiographic accompaniments of temporal lobe epileptic seizures","volume":"327","author":"Blumhardt","year":"1986","journal-title":"Lancet"},{"key":"10.1016\/j.yebeh.2011.04.056_bb0220","doi-asserted-by":"crossref","first-page":"2212","DOI":"10.1016\/S0140-6736(04)17594-6","article-title":"Cardiac arrhythmias in focal epilepsy: a prospective long term study","volume":"364","author":"Rugg-Gunn","year":"2004","journal-title":"Lancet"},{"key":"10.1016\/j.yebeh.2011.04.056_bb0225","doi-asserted-by":"crossref","first-page":"542","DOI":"10.1111\/j.1528-1157.2000.tb00207.x","article-title":"EKG abnormalities during partial seizures in refractory epilepsy","volume":"41","author":"Nei","year":"2000","journal-title":"Epilepsia"},{"key":"10.1016\/j.yebeh.2011.04.056_bb0230","doi-asserted-by":"crossref","first-page":"1169","DOI":"10.1001\/archneur.1989.00520470023018","article-title":"Electrocardiographic changes during electrographic seizures","volume":"46","author":"Keilson","year":"1989","journal-title":"Arch Neurol"},{"key":"10.1016\/j.yebeh.2011.04.056_bb0235","doi-asserted-by":"crossref","first-page":"1117","DOI":"10.1016\/S0920-1211(02)00215-2","article-title":"Heart rate and EKG changes in 102 seizures: analysis of influencing factors","volume":"52","author":"Opherk","year":"2002","journal-title":"Epilepsy Res"},{"key":"10.1016\/j.yebeh.2011.04.056_bb0240","doi-asserted-by":"crossref","first-page":"847","DOI":"10.1046\/j.1528-1157.2002.37801.x","article-title":"Heart rate changes and ECG abnormalities during epileptic seizures: prevalence and definition of an objective clinical sign","volume":"43","author":"Ziljmans","year":"2002","journal-title":"Epilepsia"},{"key":"10.1016\/j.yebeh.2011.04.056_bb0245","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1111\/j.1528-1167.2009.02281.x","article-title":"Lengthening of corrected QT during epileptic seizures","volume":"51","author":"Brotherstone","year":"2010","journal-title":"Epilepsia"},{"key":"10.1016\/j.yebeh.2011.04.056_bb0250","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1016\/S0920-1211(97)00094-6","article-title":"Heart rate variability in patients with epilepsy","volume":"30","author":"Tomson","year":"1998","journal-title":"Epilepsy Res"},{"key":"10.1016\/j.yebeh.2011.04.056_bb0255","doi-asserted-by":"crossref","first-page":"1382","DOI":"10.1136\/jnnp.2004.053777","article-title":"Suppressed circadian heart rate dynamics in temporal lobe epilepsy","volume":"76","author":"Ronkainen","year":"2005","journal-title":"J Neurol Neurosurg Psychiatry"},{"key":"10.1016\/j.yebeh.2011.04.056_bb0260","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1146\/annurev.med.50.1.249","article-title":"Insights from the study of heart rate variability","volume":"50","author":"Stein","year":"1999","journal-title":"Annu Rev Med"},{"key":"10.1016\/j.yebeh.2011.04.056_bb0265","doi-asserted-by":"crossref","first-page":"2372","DOI":"10.1093\/brain\/124.12.2372","article-title":"Interictal cardiac autonomic dysfunction in temporal lobe epilepsy demonstrated by [123]metaiodobenzylguanidine SPECT","volume":"124","author":"Druschky","year":"2001","journal-title":"Brain"},{"key":"10.1016\/j.yebeh.2011.04.056_bb0270","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1111\/j.1600-0404.2008.01135.x","article-title":"Relationship between ictal asytole and cardiac sympathetic dysfunction shown by MIGB\u2013SPECT","volume":"120","author":"Kerling","year":"2009","journal-title":"Acta Neurol Scand"},{"key":"10.1016\/j.yebeh.2011.04.056_bb0275","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1016\/j.jns.2003.07.004","article-title":"Outcome of epilepsy surgery correlates with sympathetic modulation and neuroimaging of the heart","volume":"216","author":"Hilz","year":"2003","journal-title":"J Neurol Sci"},{"key":"10.1016\/j.yebeh.2011.04.056_bb0280","doi-asserted-by":"crossref","first-page":"857","DOI":"10.1001\/archneur.55.6.857","article-title":"Patients with epilepsy who die suddenly have cardiac disease","volume":"55","author":"Natelson","year":"1998","journal-title":"Arch Neurol"},{"key":"10.1016\/j.yebeh.2011.04.056_bb0285","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1016\/S0920-1211(00)00098-X","article-title":"Does cardiac conduction pathology contribute to sudden unexpected death in epilepsy?","volume":"40","author":"Opeskin","year":"2000","journal-title":"Epilepsy Res"},{"key":"10.1016\/j.yebeh.2011.04.056_bb0290","doi-asserted-by":"crossref","first-page":"408","DOI":"10.1016\/j.ahj.2007.11.008","article-title":"Apical ballooning syndrome (Tako-Tsubo or stress cardiomyopathy): a mimic of acute myocardial infarction","volume":"155","author":"Prasad","year":"2008","journal-title":"Am Heart J"},{"key":"10.1016\/j.yebeh.2011.04.056_bb0295","doi-asserted-by":"crossref","first-page":"1977","DOI":"10.1212\/01.WNL.0000163858.77494.7A","article-title":"Postictal neurogenic stunned myocardium","volume":"64","author":"Chin","year":"2005","journal-title":"Neurology"},{"key":"10.1016\/j.yebeh.2011.04.056_bb0300","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1016\/0013-4694(87)90023-X","article-title":"Synchronisation of cardiac autonomic neural discharge with epileptogenic activity: the lock step phenonmenon","volume":"67","author":"Lathers","year":"1987","journal-title":"Electroencephalogr Clin Neurophysiol"},{"key":"10.1016\/j.yebeh.2011.04.056_bb0305","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1016\/j.yebeh.2007.09.016","article-title":"The mystery of sudden death: mechanisms for risks","volume":"12","author":"Lathers","year":"2008","journal-title":"Epilepsy Behav"},{"key":"10.1016\/j.yebeh.2011.04.056_bb0310","doi-asserted-by":"crossref","first-page":"1300","DOI":"10.1007\/s00415-006-0210-3","article-title":"Impaired baroreceptor function in temporal lobe epilepsy","volume":"253","author":"Dutsch","year":"2006","journal-title":"J Neurol"},{"key":"10.1016\/j.yebeh.2011.04.056_bb0315","doi-asserted-by":"crossref","first-page":"1190","DOI":"10.1007\/s00415-004-0501-5","article-title":"Cerebral autoregulation improves in epilepsy patients after temporal lobe surgery","volume":"251","author":"Dutsch","year":"2004","journal-title":"J Neurol"},{"key":"10.1016\/j.yebeh.2011.04.056_bb0320","doi-asserted-by":"crossref","first-page":"1727","DOI":"10.1212\/WNL.42.9.1727","article-title":"Cardiovascular effects of human insular cortex stimulation","volume":"42","author":"Oppenheimer","year":"1992","journal-title":"Neurology"},{"key":"10.1016\/j.yebeh.2011.04.056_bb0325","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1136\/jnnp.56.2.141","article-title":"Ictal\/post-ictal SPECT in the pre-surgical localisation of complex partial seizures","volume":"56","author":"Duncan","year":"1993","journal-title":"J Neurol Neurosurg Psychiatry"},{"key":"10.1016\/j.yebeh.2011.04.056_bb0330","doi-asserted-by":"crossref","first-page":"104","DOI":"10.1159\/000114609","article-title":"Circulatory and respiratory changes in spontaneous epileptic seizures in man","volume":"12","author":"Magnaes","year":"1974","journal-title":"Eur Neurol"},{"key":"10.1016\/j.yebeh.2011.04.056_bb0335","doi-asserted-by":"crossref","first-page":"743","DOI":"10.1111\/j.1528-1157.1988.tb04229.x","article-title":"Persistence of impaired auto-regulation of cerebral blood flow in the post-ictal period in piglets","volume":"29","author":"Hascoet","year":"1988","journal-title":"Epilepsia"},{"key":"10.1016\/j.yebeh.2011.04.056_bb0340","doi-asserted-by":"crossref","first-page":"3239","DOI":"10.1093\/brain\/awn277","article-title":"Ictal hypoxaemia in localisation related epilepsy: analysis of incidence, severity and risk factors","volume":"131","author":"Bateman","year":"2008","journal-title":"Brain"},{"key":"10.1016\/j.yebeh.2011.04.056_bb0345","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1136\/jnnp.60.3.297","article-title":"Apnoea and bradycardia during epileptic seizures: relation to sudden death in epilepsy","volume":"60","author":"Nashef","year":"1996","journal-title":"J Neurol Neurosurg Psychiatry"},{"key":"10.1016\/j.yebeh.2011.04.056_bb0350","doi-asserted-by":"crossref","first-page":"588","DOI":"10.1002\/ana.410420409","article-title":"Central apnea and acute cardiac ischemia in a sheep model of epileptic sudden death","volume":"42","author":"Johnston","year":"1997","journal-title":"Ann Neurol"},{"key":"10.1016\/j.yebeh.2011.04.056_bb0355","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1016\/j.seizure.2006.02.007","article-title":"Sudden death in epilepsy: an experimental animal model","volume":"15","author":"Mameli","year":"2006","journal-title":"Seizure"},{"key":"10.1016\/j.yebeh.2011.04.056_bb0360","doi-asserted-by":"crossref","first-page":"993","DOI":"10.1111\/j.0013-9580.2004.02304.x","article-title":"Oxygenation prevents sudden death in seizure-prone mice","volume":"45","author":"Venit","year":"2004","journal-title":"Epilepsia"},{"key":"10.1016\/j.yebeh.2011.04.056_bb0365","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1111\/j.1528-1167.2006.00365.x","article-title":"Evidence supporting a role of serotonin in modulation of sudden death induced by seizures in DBA\/2 mice","volume":"47","author":"Tupal","year":"2006","journal-title":"Epilepsia"},{"key":"10.1016\/j.yebeh.2011.04.056_bb0370","doi-asserted-by":"crossref","first-page":"2211","DOI":"10.1111\/j.1528-1167.2010.02594.x","article-title":"Serotonin reuptake inhibitors are associated with reduced severity of ictal hypoxemia in medically refractory partial epilepsy","volume":"51","author":"Bateman","year":"2010","journal-title":"Epilepsia"},{"key":"10.1016\/j.yebeh.2011.04.056_bb0375","doi-asserted-by":"crossref","first-page":"302","DOI":"10.1016\/j.sleep.2007.03.005","article-title":"Neurobiology of REM and NREM sleep","volume":"8","author":"McCarley","year":"2007","journal-title":"Sleep Med"},{"key":"10.1016\/j.yebeh.2011.04.056_bb0380","doi-asserted-by":"crossref","first-page":"618","DOI":"10.1002\/ana.410320504","article-title":"Adenosine: a potential mediator of seizure arrest and postictal refractoriness","volume":"32","author":"During","year":"1992","journal-title":"Ann Neurol"},{"key":"10.1016\/j.yebeh.2011.04.056_bb0385","doi-asserted-by":"crossref","first-page":"465","DOI":"10.1111\/j.1528-1167.2009.02248.x","article-title":"A novel mouse model for sudden unexpected death in epilepsy (SUDEP): role of impaired adenosine clearance","volume":"51","author":"Shen","year":"2010","journal-title":"Epilepsia"},{"key":"10.1016\/j.yebeh.2011.04.056_bb0390","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1111\/j.1600-0404.1983.tb04814.x","article-title":"Cardiac conduction disturbances during carbamazepine therapy","volume":"68","author":"Boesin","year":"1983","journal-title":"Acta Neurol Scand"},{"key":"10.1016\/j.yebeh.2011.04.056_bb0395","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1111\/j.1600-0404.2006.00730.x","article-title":"Lamotrigine in idiopathic epilepsy: increased risk of cardiac death?","volume":"115","author":"Aurlien","year":"2007","journal-title":"Acta Neurol Scand"},{"year":"2010","series-title":"Increased incidence of sudden unexpected death in epilepsy (SUDEP) with lamotrigine in Rogoland County, Norway","author":"Aurlien","key":"10.1016\/j.yebeh.2011.04.056_bb0400"},{"key":"10.1016\/j.yebeh.2011.04.056_bb0405","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1016\/j.eplepsyres.2004.10.002","article-title":"Effects of the antiepileptic drugs lamotrigine, topiramate and gabapentin on hERG potassium currents","volume":"63","author":"Danielsson","year":"2005","journal-title":"Epilepsy Res"},{"key":"10.1016\/j.yebeh.2011.04.056_bb0410","doi-asserted-by":"crossref","first-page":"463","DOI":"10.1038\/nature04710","article-title":"hERG potassium channels and cardiac arrhythmia","volume":"440","author":"Sanguinetti","year":"2006","journal-title":"Nature"},{"key":"10.1016\/j.yebeh.2011.04.056_bb0415","doi-asserted-by":"crossref","first-page":"396","DOI":"10.1111\/j.1365-2125.2008.03250.x","article-title":"Lamotrigine does not prolong QTc in a thorough QT\/QTc study in healthy subjects","volume":"66","author":"Dixon","year":"2008","journal-title":"Br J Clin Pharm"},{"key":"10.1016\/j.yebeh.2011.04.056_bb0420","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1016\/0387-7604(95)00139-5","article-title":"Hematologic manifestations and impaired liver synthetic function during valproate monotherapy","volume":"18","author":"Hauser","year":"1996","journal-title":"Brain Dev"},{"key":"10.1016\/j.yebeh.2011.04.056_bb0425","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1016\/j.yebeh.2007.10.015","article-title":"Erythrocyte and plasma fatty acid profiles in patients with epilepsy: does carbamazepine affect omega-3 fatty acid concentrations?","volume":"12","author":"Yuen","year":"2008","journal-title":"Epilepsy Behav"},{"key":"10.1016\/j.yebeh.2011.04.056_bb0430","doi-asserted-by":"crossref","first-page":"1178","DOI":"10.1161\/01.CIR.102.10.1178","article-title":"Spectrum of mutations on long QT syndrome genes: KVLQT1, HERG, SCN5A, KCNEI, KCNE2","volume":"102","author":"Splawski","year":"2000","journal-title":"Circulation"},{"key":"10.1016\/j.yebeh.2011.04.056_bb0435","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1111\/j.1750-3639.2010.00438.x","article-title":"Post mortem review and genetic analysis of sudden unexpected death in epilepsy (SUDEP) cases","volume":"21","author":"Tu","year":"2011","journal-title":"Brain Pathol"},{"key":"10.1016\/j.yebeh.2011.04.056_bb0440","doi-asserted-by":"crossref","first-page":"1063","DOI":"10.1016\/j.ncl.2009.08.003","article-title":"Sudden unexplained death in epilepsy: update and reflections","volume":"27","author":"Nashef","year":"2009","journal-title":"Neurol Clin"},{"key":"10.1016\/j.yebeh.2011.04.056_bb0445","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1016\/S0735-1097(00)00700-2","article-title":"Misdiagnosis of epilepsy: many seizure like attacks have a cardiovascular cause","volume":"36","author":"Zaidi","year":"2000","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.yebeh.2011.04.056_bb0450","doi-asserted-by":"crossref","DOI":"10.1136\/bmj.b4815","article-title":"Easily missed? Long QT syndrome","volume":"340","author":"Abrams","year":"2010","journal-title":"BMJ"},{"issue":"Suppl. 9","key":"10.1016\/j.yebeh.2011.04.056_bb0455","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1111\/j.1528-1167.2008.01933.x","article-title":"Should all patients be told about sudden unexplained death in epilepsy (SUDEP?): pros and cons","volume":"49","author":"Brodie","year":"2008","journal-title":"Epilepsia"},{"year":"2004","series-title":"Clinical guidelines and evidence review for the epilepsies: diagnosis and management in adults and children in primary and secondary care","author":"Stokes","key":"10.1016\/j.yebeh.2011.04.056_bb0460"},{"year":"2003","series-title":"Diagnosis and management of epilepsy in adults: a national clinical guideline","key":"10.1016\/j.yebeh.2011.04.056_bb0465"},{"key":"10.1016\/j.yebeh.2011.04.056_bb0470","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1136\/jnnp.2005.066852","article-title":"Sudden unexpected death in epilepsy: Don't ask? Don't tell?","volume":"77","author":"Morton","year":"1996","journal-title":"J Neurol Neurosurg Psychiatry"},{"key":"10.1016\/j.yebeh.2011.04.056_bb0475","doi-asserted-by":"crossref","first-page":"331","DOI":"10.1007\/s10072-010-0365-7","article-title":"Sudden unexpected death in epilepsy (SUDEP): a pilot study on truth telling among Italian epileptologists","volume":"32","author":"Vegni","year":"2011","journal-title":"Neurol Sci"},{"key":"10.1016\/j.yebeh.2011.04.056_bb0480","doi-asserted-by":"crossref","first-page":"917","DOI":"10.1111\/j.1528-1167.2008.01906.x","article-title":"Report of the American Epilepsy Society and the Epilepsy Foundation Joint Task Force on Sudden Unexplained Death in Epilepsy","volume":"50","author":"So","year":"2009","journal-title":"Epilepsia"},{"key":"10.1016\/j.yebeh.2011.04.056_bb0485","doi-asserted-by":"crossref","first-page":"1069","DOI":"10.1111\/j.1528-1167.2009.02397.x","article-title":"Definition of drug resistant epilepsy: consensus proposal by the ad hoc Task Force of the ILAE Commission on Therapeutic Strategies","volume":"151","author":"Kwan","year":"2010","journal-title":"Epilepsia"}],"container-title":["Epilepsy &amp; Behavior"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1525505011002265?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1525505011002265?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,26]],"date-time":"2025-10-26T18:22:59Z","timestamp":1761502979000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1525505011002265"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,8]]},"references-count":97,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2011,8]]}},"alternative-id":["S1525505011002265"],"URL":"https:\/\/doi.org\/10.1016\/j.yebeh.2011.04.056","relation":{},"ISSN":["1525-5050"],"issn-type":[{"type":"print","value":"1525-5050"}],"subject":[],"published":{"date-parts":[[2011,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Sudden unexpected death in epilepsy","name":"articletitle","label":"Article Title"},{"value":"Epilepsy & Behavior","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.yebeh.2011.04.056","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2011 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}