{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,19]],"date-time":"2026-10-19T23:22:34Z","timestamp":1792452154087,"version":"4.5.0"},"reference-count":143,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2014,9,1]],"date-time":"2014-09-01T00:00:00Z","timestamp":1409529600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":["epilepsybehavior.com","clinicalkey.jp","clinicalkey.com","clinicalkey.es","clinicalkey.com.au","clinicalkey.fr","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Epilepsy & Behavior"],"published-print":{"date-parts":[[2014,9]]},"DOI":"10.1016\/j.yebeh.2013.10.020","type":"journal-article","created":{"date-parts":[[2013,11,21]],"date-time":"2013-11-21T15:23:04Z","timestamp":1385047384000},"page":"148-159","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":196,"special_numbering":"C","title":["Early-life stress and HPA axis trigger recurrent adulthood depression"],"prefix":"10.1016","volume":"38","author":[{"given":"Mario F.","family":"Juruena","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"4","key":"10.1016\/j.yebeh.2013.10.020_bb0005","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1111\/j.1601-5215.2011.00584.x","article-title":"An integrative science approach: neuroscience in the DSM-V and ICD-11","volume":"23","author":"Juruena","year":"2011","journal-title":"Acta Neuropsychiatr"},{"key":"10.1016\/j.yebeh.2013.10.020_bb0010","doi-asserted-by":"crossref","first-page":"219","DOI":"10.3922\/j.psns.2011.2.007","article-title":"Analysis of the occurrence of early life stress in adult psychiatric patients: a systematic review","volume":"4","author":"Martins","year":"2011","journal-title":"Psychol Neurosci"},{"issue":"2","key":"10.1016\/j.yebeh.2013.10.020_bb0015","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1176\/ajp.141.2.247","article-title":"Correlation between the dexamethasone suppression test in depressed patients and clinical response","volume":"141","author":"Nemeroff","year":"1984","journal-title":"Am J Psychiatry"},{"issue":"7","key":"10.1016\/j.yebeh.2013.10.020_bb0020","doi-asserted-by":"crossref","first-page":"413","DOI":"10.1056\/NEJM198808183190706","article-title":"Clinical and biochemical manifestations of depression. Relation to the neurobiology of stress (2)","volume":"319","author":"Gold","year":"1988","journal-title":"N Engl J Med"},{"issue":"3","key":"10.1016\/j.yebeh.2013.10.020_bb0025","first-page":"269","article-title":"Brain corticosteroid receptor balance in health and disease","volume":"19","author":"de Kloet","year":"1998","journal-title":"Endocr Rev"},{"issue":"2","key":"10.1016\/j.yebeh.2013.10.020_bb0030","doi-asserted-by":"crossref","first-page":"108","DOI":"10.1016\/S0893-133X(99)00129-3","article-title":"Allostasis and allostatic load: implications for neuropsychopharmacology","volume":"22","author":"McEwen","year":"2000","journal-title":"Neuropsychopharmacology"},{"issue":"3","key":"10.1016\/j.yebeh.2013.10.020_bb0035","doi-asserted-by":"crossref","first-page":"459","DOI":"10.1677\/joe.0.1150459","article-title":"Relative occupation of type-I and type-II corticosteroid receptors in rat brain following stress and dexamethasone treatment: functional implications","volume":"115","author":"Reul","year":"1987","journal-title":"J Endocrinol"},{"issue":"9","key":"10.1016\/j.yebeh.2013.10.020_bb0040","doi-asserted-by":"crossref","first-page":"887","DOI":"10.1016\/0896-6273(88)90136-5","article-title":"The neuronal mineralocorticoid receptor as a mediator of glucocorticoid response","volume":"1","author":"Arriza","year":"1988","journal-title":"Neuron"},{"issue":"1","key":"10.1016\/j.yebeh.2013.10.020_bb0045","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/0304-3940(85)90372-6","article-title":"Immunocytochemical studies on the localization of glucocorticoid receptor immunoreactive nerve cells in the lower brain stem and spinal cord of the male rat using a monoclonal antibody against rat liver glucocorticoid receptor","volume":"60","author":"Fuxe","year":"1985","journal-title":"Neurosci Lett"},{"issue":"3","key":"10.1016\/j.yebeh.2013.10.020_bb0050","doi-asserted-by":"crossref","first-page":"216","DOI":"10.1159\/000127275","article-title":"Corticosteroid receptor function is decreased in depressed patients","volume":"65","author":"Modell","year":"1997","journal-title":"Neuroendocrinology"},{"issue":"6","key":"10.1016\/j.yebeh.2013.10.020_bb0055","doi-asserted-by":"crossref","first-page":"354","DOI":"10.1046\/j.1601-5215.2003.00051.x","article-title":"Molecular mechanisms of glucocorticoid receptor sensitivity and relevance to affective disorders","volume":"15","author":"Juruena","year":"2003","journal-title":"Acta Neuropsychiatr"},{"issue":"127","key":"10.1016\/j.yebeh.2013.10.020_bb0060","doi-asserted-by":"crossref","first-page":"1463","DOI":"10.1001\/archsurg.1992.01420120097017","article-title":"The hypothalamic\u2013pituitary\u2013adrenal\u2013immune axis. A critical assessment","author":"Lilly","year":"1992","journal-title":"Arch Surg"},{"issue":"3","key":"10.1016\/j.yebeh.2013.10.020_bb0065","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1590\/S1516-44462004000300009","article-title":"The hypothalamic pituitary adrenal axis, glucocorticoid receptor function and relevance to depression","volume":"26","author":"Juruena","year":"2004","journal-title":"Rev Bras Psiquiatr"},{"key":"10.1016\/j.yebeh.2013.10.020_bb0070","doi-asserted-by":"crossref","first-page":"393","DOI":"10.1111\/j.1365-2826.2006.01429.x","article-title":"Do corticosteroids damage the brain?","volume":"18","author":"Herbert","year":"2006","journal-title":"J Neuroendocrinol"},{"key":"10.1016\/j.yebeh.2013.10.020_bb0075","doi-asserted-by":"crossref","first-page":"1351","DOI":"10.1056\/NEJM199505183322008","article-title":"The hypothalamic\u2013pituitary\u2013adrenal axis and immune-mediated inflammation","volume":"332","author":"Chrousos","year":"1995","journal-title":"N Engl J Med"},{"key":"10.1016\/j.yebeh.2013.10.020_bb0080","doi-asserted-by":"crossref","first-page":"172","DOI":"10.1016\/S0006-291X(05)80189-5","article-title":"Interaction between corticosteroid binding globulin and activated leukocytes in vitro","volume":"172","author":"Hammond","year":"1990","journal-title":"Biochem Biophys Res Commun"},{"key":"10.1016\/j.yebeh.2013.10.020_bb0085","doi-asserted-by":"crossref","first-page":"287","DOI":"10.1111\/j.1749-6632.1988.tb48873.x","article-title":"Influence of naturally occurring and synthetic glucocorticoids on corticosteroid-binding globulin-steroid interaction in human peripheral plasma","volume":"538","author":"Frairia","year":"1988","journal-title":"Ann N Y Acad Sci"},{"key":"10.1016\/j.yebeh.2013.10.020_bb0090","doi-asserted-by":"crossref","first-page":"304","DOI":"10.1097\/00000441-199111000-00009","article-title":"Roles of lipid turnover in transmembrane signal transduction","volume":"302","author":"Ganong","year":"1991","journal-title":"Am J Med Sci"},{"key":"10.1016\/j.yebeh.2013.10.020_bb0095","doi-asserted-by":"crossref","first-page":"671","DOI":"10.1152\/physrev.1989.69.3.671","article-title":"Neurophysiology of the suprachiasmatic circadian pacemaker in rodents","volume":"69","author":"Meijer","year":"1989","journal-title":"Physiol Rev"},{"issue":"127","key":"10.1016\/j.yebeh.2013.10.020_bb0100","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1530\/acta.0.1270193","article-title":"Corticotropin-releasing hormone in health and disease: an update","author":"Ur","year":"1992","journal-title":"Acta Endocrinol (Copenh)"},{"key":"10.1016\/j.yebeh.2013.10.020_bb0105","doi-asserted-by":"crossref","first-page":"124","DOI":"10.1196\/annals.1308.013","article-title":"Puberty, ovarian steroids, and stress","volume":"1021","author":"Young","year":"2004","journal-title":"Ann N Y Acad Sci"},{"key":"10.1016\/j.yebeh.2013.10.020_bb0110","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1038\/icb.1956.11","article-title":"Hydrocortisone and A.C.T.H. release","volume":"34","author":"Rose","year":"1956","journal-title":"Aust J Exp Biol Med Sci"},{"key":"10.1016\/j.yebeh.2013.10.020_bb0115","doi-asserted-by":"crossref","first-page":"58","DOI":"10.1152\/ajplegacy.1957.192.1.58","article-title":"The steroid feedback mechanism","volume":"192","author":"Schapiro","year":"1958","journal-title":"Am J Physiol"},{"key":"10.1016\/j.yebeh.2013.10.020_bb0120","doi-asserted-by":"crossref","first-page":"811","DOI":"10.1210\/endo-76-5-811","article-title":"Effect of hypothalamic and mesencephalic steroid implications on ACTH feedback mechanisms","volume":"76","author":"Corbin","year":"1965","journal-title":"Endocrinology"},{"key":"10.1016\/j.yebeh.2013.10.020_bb0125","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1210\/edrv-5-1-1","article-title":"Corticosteroid inhibition of ACTH secretion","volume":"5","author":"Keller-Wood","year":"1984","journal-title":"Endocr Rev"},{"key":"10.1016\/j.yebeh.2013.10.020_bb0130","doi-asserted-by":"crossref","first-page":"296","DOI":"10.1016\/S1357-4310(97)88908-3","article-title":"Lipocortin 1: a second messenger of glucocorticoid action in the hypothalamo-pituitary-adrenocortical axis","volume":"3","author":"Buckingham","year":"1997","journal-title":"Mol Med Today"},{"key":"10.1016\/j.yebeh.2013.10.020_bb0135","first-page":"E489","article-title":"Interaction between stimulus intensity and corticosteroid feedback in control of ACTH","volume":"247","author":"Keller-Wood","year":"1984","journal-title":"Am J Physiol"},{"key":"10.1016\/j.yebeh.2013.10.020_bb0140","first-page":"113","article-title":"Regulation of ACTH secretion: variations on a theme of B","volume":"43","author":"Dallman","year":"1987","journal-title":"Recent Prog Horm Res"},{"key":"10.1016\/j.yebeh.2013.10.020_bb0145","doi-asserted-by":"crossref","first-page":"2844","DOI":"10.1210\/endo-124-6-2844","article-title":"Pharmacological evidence that the inhibition of diurnal adrenocorticotropin secretion by corticosteroids is mediated via type I corticosterone-preferring receptors","volume":"124","author":"Dallman","year":"1989","journal-title":"Endocrinology"},{"issue":"1","key":"10.1016\/j.yebeh.2013.10.020_bb0150","first-page":"115","article-title":"The development and application of the prednisolone suppression test in psychiatry: a novel tool for assessing glucocorticoid and mineralocorticoid receptor function","volume":"1","author":"Juruena","year":"2010","journal-title":"Mind Brain J Psychiatry"},{"key":"10.1016\/j.yebeh.2013.10.020_bb0155","doi-asserted-by":"crossref","first-page":"2718","DOI":"10.1210\/endo.139.6.6029","article-title":"Evidence for mineralocorticoid receptor facilitation of glucocorticoid receptor-dependent regulation of hypothalamic\u2013pituitary\u2013adrenal axis activity","volume":"139","author":"Spencer","year":"1998","journal-title":"Endocrinology"},{"key":"10.1016\/j.yebeh.2013.10.020_bb0160","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1016\/0960-0760(95)00268-5","article-title":"The Ernst Schering Poster Award. Intracellular traffic of steroid hormone receptors","volume":"56","author":"Guiochon-Mantel","year":"1996","journal-title":"J Steroid Biochem Mol Biol"},{"key":"10.1016\/j.yebeh.2013.10.020_bb0165","doi-asserted-by":"crossref","first-page":"21455","DOI":"10.1016\/S0021-9258(20)80556-0","article-title":"The role of heat shock proteins in regulating the function, folding, and trafficking of the glucocorticoid receptor","volume":"268","author":"Pratt","year":"1993","journal-title":"J Biol Chem"},{"key":"10.1016\/j.yebeh.2013.10.020_bb0170","doi-asserted-by":"crossref","first-page":"2973","DOI":"10.1073\/pnas.95.6.2973","article-title":"Subcellular localization of mineralocorticoid receptors in living cells: effects of receptor agonists and antagonists","volume":"95","author":"Fejes-Toth","year":"1998","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.yebeh.2013.10.020_bb0175","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1016\/0922-4106(93)90072-H","article-title":"Pharmacological and functional characterization of human mineralocorticoid and glucocorticoid receptor ligands","volume":"247","author":"Rupprecht","year":"1993","journal-title":"Eur J Pharmacol"},{"key":"10.1016\/j.yebeh.2013.10.020_bb0180","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1016\/0306-4530(87)90040-0","article-title":"Feedback action and tonic influence of corticosteroids on brain function: a concept arising from the heterogeneity of brain receptor systems","volume":"12","author":"de Kloet","year":"1987","journal-title":"Psychoneuroendocrinology"},{"key":"10.1016\/j.yebeh.2013.10.020_bb0185","doi-asserted-by":"crossref","first-page":"E1082","DOI":"10.1152\/ajpendo.00521.2004","article-title":"Disruption of mineralocorticoid receptor function increases corticosterone responding to a mild, but not moderate, psychological stressor","volume":"288","author":"Pace","year":"2005","journal-title":"Am J Physiol Endocrinol Metab"},{"key":"10.1016\/j.yebeh.2013.10.020_bb0190","first-page":"296","article-title":"The role of corticotropin-releasing factor in the pathophysiology of affective and anxiety disorders: laboratory and clinical studies","volume":"172","author":"Owens","year":"1993","journal-title":"Ciba Found Symp"},{"key":"10.1016\/j.yebeh.2013.10.020_bb0195","doi-asserted-by":"crossref","first-page":"463","DOI":"10.1038\/nrn1683","article-title":"Stress and the brain: from adaptation to disease","volume":"6","author":"de Kloet","year":"2005","journal-title":"Nat Rev Neurosci"},{"key":"10.1016\/j.yebeh.2013.10.020_bb0200","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1016\/0165-1781(92)90070-J","article-title":"In vivo assessment of pituitary volume with magnetic resonance imaging and systematic stereology: relationship to dexamethasone suppression test results in patients","volume":"44","author":"Axelson","year":"1992","journal-title":"Psychiatry Res"},{"key":"10.1016\/j.yebeh.2013.10.020_bb0205","doi-asserted-by":"crossref","first-page":"423","DOI":"10.1016\/j.psyneuen.2003.10.009","article-title":"Do antidepressants regulate how cortisol affects the brain? 2003 Curt Richter Award Paper","volume":"29","author":"Pariante","year":"2004","journal-title":"Psychoneuroendocrinology"},{"key":"10.1016\/j.yebeh.2013.10.020_bb0210","doi-asserted-by":"crossref","first-page":"477","DOI":"10.1016\/S0893-133X(00)00159-7","article-title":"The corticosteroid receptor hypothesis of depression","volume":"23","author":"Holsboer","year":"2000","journal-title":"Neuropsychopharmacology"},{"key":"10.1016\/j.yebeh.2013.10.020_bb0215","doi-asserted-by":"crossref","first-page":"865","DOI":"10.1016\/S0022-3999(02)00429-4","article-title":"Hypothalamic\u2013pituitary\u2013adrenal axis, neuroendocrine factors and stress","volume":"53","author":"Tsigos","year":"2002","journal-title":"J Psychosom Res"},{"key":"10.1016\/j.yebeh.2013.10.020_bb0220","first-page":"20","article-title":"Overlap between atypical depression, seasonal affective disorder and chronic fatigue syndrome","volume":"29","author":"Juruena","year":"2007","journal-title":"Rev Bras Psiquiatr"},{"key":"10.1016\/j.yebeh.2013.10.020_bb0225","doi-asserted-by":"crossref","first-page":"3545","DOI":"10.1210\/jcem.86.8.7735","article-title":"Hypothalamo-pituitary-adrenal axis dysfunction in chronic fatigue syndrome, and the effects of low-dose hydrocortisone therapy","volume":"86","author":"Cleare","year":"2001","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1016\/j.yebeh.2013.10.020_bb0230","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1038\/nrendo.2011.153","article-title":"Hypothalamic\u2013pituitary\u2013adrenal axis dysfunction in chronic fatigue syndrome","volume":"8","author":"Cleare","year":"2012","journal-title":"Nat Rev Endocrinol"},{"key":"10.1016\/j.yebeh.2013.10.020_bb0235","doi-asserted-by":"crossref","first-page":"254","DOI":"10.1038\/sj.mp.4001032","article-title":"Organization of the stress system and its dysregulation in melancholic and atypical depression: high vs low CRH\/NE states","volume":"7","author":"Gold","year":"2002","journal-title":"Mol Psychiatry"},{"issue":"21","key":"10.1016\/j.yebeh.2013.10.020_bb0240","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1016\/S0193-953X(05)70006-X","article-title":"Psychoneuroendocrinology of depression. Hypothalamic\u2013pituitary\u2013adrenal axis","author":"Plotsky","year":"1998","journal-title":"Psychiatr Clin North Am"},{"key":"10.1016\/j.yebeh.2013.10.020_bb0245","doi-asserted-by":"crossref","first-page":"797","DOI":"10.1016\/0006-3223(95)00064-X","article-title":"Combined dexamethasone\/corticotropin-releasing hormone test in acute and remitted manic patients, in acute depression, and in normal controls: I","volume":"38","author":"Schmider","year":"1995","journal-title":"Biol Psychiatry"},{"key":"10.1016\/j.yebeh.2013.10.020_bb0250","doi-asserted-by":"crossref","first-page":"496","DOI":"10.1192\/bjp.184.6.496","article-title":"Hypothalamic\u2013pituitary\u2013adrenal axis function in patients with bipolar disorder","volume":"184","author":"Watson","year":"2004","journal-title":"Br J Psychiatry"},{"key":"10.1016\/j.yebeh.2013.10.020_bb0255","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1016\/S0022-3956(98)90056-5","article-title":"The rationale for corticotropin-releasing hormone receptor (CRH-R) antagonists to treat depression and anxiety","volume":"33","author":"Holsboer","year":"1999","journal-title":"J Psychiatr Res"},{"key":"10.1016\/j.yebeh.2013.10.020_bb0260","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1111\/j.1365-2826.1994.tb00563.x","article-title":"Similar age related increase of vasopressin colocalization in paraventricular corticotropin-releasing hormone neurons in controls and Alzheimer patients","volume":"6","author":"Raadsheer","year":"1994","journal-title":"J Neuroendocrinol"},{"key":"10.1016\/j.yebeh.2013.10.020_bb0265","doi-asserted-by":"crossref","first-page":"390","DOI":"10.1192\/bjp.177.5.390","article-title":"Future therapeutic targets in mood disorders: the glucocorticoid receptor","volume":"177","author":"McQuade","year":"2000","journal-title":"Br J Psychiatry"},{"key":"10.1016\/j.yebeh.2013.10.020_bb0270","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1016\/0165-0327(86)90011-X","article-title":"Multisteroid analysis after DST in depressed patients\u2014a controlled study","volume":"10","author":"Holsboer","year":"1986","journal-title":"J Affect Disord"},{"key":"10.1016\/j.yebeh.2013.10.020_bb0275","doi-asserted-by":"crossref","first-page":"1789","DOI":"10.1210\/endo.139.4.5917","article-title":"Penetration of dexamethasone into brain glucocorticoid targets is enhanced in mdr1A P-glycoprotein knockout mice","volume":"139","author":"Meijer","year":"1998","journal-title":"Endocrinology"},{"key":"10.1016\/j.yebeh.2013.10.020_bb0280","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1176\/ajp.141.2.247","article-title":"Correlation between the dexamethasone suppression test in depressed patients and clinical response","volume":"141","author":"Nemeroff","year":"1984","journal-title":"Am J Psychiatry"},{"key":"10.1016\/j.yebeh.2013.10.020_bb0285","doi-asserted-by":"crossref","first-page":"577","DOI":"10.1001\/archpsyc.1988.01800300075009","article-title":"Reduced corticotropin releasing factor binding sites in the frontal cortex of suicide victims","volume":"45","author":"Nemeroff","year":"1988","journal-title":"Arch Gen Psychiatry"},{"key":"10.1016\/j.yebeh.2013.10.020_bb0290","doi-asserted-by":"crossref","first-page":"1372","DOI":"10.1176\/ajp.152.9.1372","article-title":"Corticotropin-releasing hormone mRNA levels in the paraventricular nucleus of patients with Alzheimer's disease and depression","volume":"152","author":"Raadsheer","year":"1995","journal-title":"Am J Psychiatry"},{"key":"10.1016\/j.yebeh.2013.10.020_bb0295","doi-asserted-by":"crossref","first-page":"656","DOI":"10.1176\/ajp.150.4.656","article-title":"Association of fluoxetine treatment with reductions in CSF concentrations of corticotropin-releasing hormone and arginine vasopressin in patients with major depression","volume":"150","author":"De Bellis","year":"1993","journal-title":"Am J Psychiatry"},{"key":"10.1016\/j.yebeh.2013.10.020_bb0300","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1016\/S0893-133X(97)00144-9","article-title":"Hormonal response pattern in the combined DEX-CRH test is stable over time in subjects at high familial risk for affective disorders","volume":"18","author":"Modell","year":"1998","journal-title":"Neuropsychopharmacology"},{"key":"10.1016\/j.yebeh.2013.10.020_bb0305","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1016\/0960-0760(91)90069-H","article-title":"Treatment of major depression with steroid suppressive drugs","volume":"39","author":"Murphy","year":"1991","journal-title":"J Steroid Biochem Mol Biol"},{"key":"10.1016\/j.yebeh.2013.10.020_bb0310","doi-asserted-by":"crossref","first-page":"391","DOI":"10.1016\/S0006-3223(00)01088-X","article-title":"Glucocorticoid receptors in major depression: relevance to pathophysiology and treatment","volume":"49","author":"Pariante","year":"2001","journal-title":"Biol Psychiatry"},{"key":"10.1016\/j.yebeh.2013.10.020_bb0315","doi-asserted-by":"crossref","first-page":"925","DOI":"10.1001\/archpsyc.57.10.925","article-title":"Glucocorticoids and hippocampal atrophy in neuropsychiatric disorders","volume":"57","author":"Sapolsky","year":"2000","journal-title":"Arch Gen Psychiatry"},{"issue":"896","key":"10.1016\/j.yebeh.2013.10.020_bb0320","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1111\/j.1749-6632.1999.tb08103.x","article-title":"Protective and damaging effects of mediators of stress. Elaborating and testing the concepts of allostasis and allostatic load","author":"McEwen","year":"1999","journal-title":"Ann N Y Acad Sci"},{"key":"10.1016\/j.yebeh.2013.10.020_bb0325","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1016\/j.physbeh.2006.08.025","article-title":"Measuring cortisol in human psychobiological studies","volume":"90","author":"Levine","year":"2007","journal-title":"Physiol Behav"},{"key":"10.1016\/j.yebeh.2013.10.020_bb0330","doi-asserted-by":"crossref","first-page":"550","DOI":"10.1016\/j.jpsychires.2005.08.002","article-title":"Assessment of HPA-axis function in posttraumatic stress disorder: pharmacological and non-pharmacological challenge tests, a review","volume":"40","author":"de Kloet","year":"2006","journal-title":"J Psychiatr Res"},{"issue":"7556","key":"10.1016\/j.yebeh.2013.10.020_bb0335","doi-asserted-by":"crossref","first-page":"1373","DOI":"10.1016\/S0140-6736(68)92072-2","article-title":"Pituitary\u2013adrenal function in depression","volume":"1","author":"Carroll","year":"1968","journal-title":"Lancet"},{"issue":"12","key":"10.1016\/j.yebeh.2013.10.020_bb0340","doi-asserted-by":"crossref","first-page":"1193","DOI":"10.1001\/archpsyc.1985.01790350067012","article-title":"The dexamethasone suppression test for diagnosis and prognosis in psychiatry. Commentary and review","volume":"42","author":"Arana","year":"1985","journal-title":"Arch Gen Psychiatry"},{"issue":"11","key":"10.1016\/j.yebeh.2013.10.020_bb0345","doi-asserted-by":"crossref","first-page":"1618","DOI":"10.1176\/ajp.150.11.1618","article-title":"The DST as a predictor of outcome in depression: a meta-analysis","volume":"150","author":"Ribeiro","year":"1993","journal-title":"Am J Psychiatry"},{"issue":"1","key":"10.1016\/j.yebeh.2013.10.020_bb0350","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1001\/archpsyc.1981.01780260017001","article-title":"A specific laboratory test for the diagnosis of melancholia. Standardization, validation, and clinical utility","volume":"38","author":"Carroll","year":"1981","journal-title":"Arch Gen Psychiatry"},{"key":"10.1016\/j.yebeh.2013.10.020_bb0355","doi-asserted-by":"crossref","first-page":"292","DOI":"10.1192\/bjp.140.3.292","article-title":"The dexamethasone suppression test for melancholia","volume":"140","author":"Carroll","year":"1982","journal-title":"Br J Psychiatry"},{"issue":"4","key":"10.1016\/j.yebeh.2013.10.020_bb0360","doi-asserted-by":"crossref","first-page":"489","DOI":"10.1176\/ajp.151.4.489","article-title":"Melancholic symptom features and DSM-IV","volume":"151","author":"Rush","year":"1994","journal-title":"Am J Psychiatry"},{"issue":"10","key":"10.1016\/j.yebeh.2013.10.020_bb0365","doi-asserted-by":"crossref","first-page":"470","DOI":"10.4088\/JCP.v57n1006","article-title":"The dexamethasone suppression test in patients with mood disorders","volume":"57","author":"Rush","year":"1996","journal-title":"J Clin Psychiatry"},{"issue":"11","key":"10.1016\/j.yebeh.2013.10.020_bb0370","doi-asserted-by":"crossref","first-page":"1497","DOI":"10.1176\/ajp.154.11.1497","article-title":"DST studies in psychotic depression: a meta-analysis","volume":"154","author":"Nelson","year":"1997","journal-title":"Am J Psychiatry"},{"issue":"10","key":"10.1016\/j.yebeh.2013.10.020_bb0375","doi-asserted-by":"crossref","first-page":"1042","DOI":"10.1016\/0006-3223(91)90360-X","article-title":"Effect of age on the cortisol response to human corticotropin-releasing hormone in depressed patients pretreated with dexamethasone","volume":"29","author":"von Bardeleben","year":"1991","journal-title":"Biol Psychiatry"},{"issue":"17","key":"10.1016\/j.yebeh.2013.10.020_bb0380","doi-asserted-by":"crossref","first-page":"1613","DOI":"10.1016\/0024-3205(85)90480-1","article-title":"Combined administration of human corticotropin-releasing factor and lysine vasopressin induces cortisol escape from dexamethasone suppression in healthy subjects","volume":"37","author":"von Bardeleben","year":"1985","journal-title":"Life Sci"},{"issue":"4","key":"10.1016\/j.yebeh.2013.10.020_bb0385","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1016\/0022-3956(94)90017-5","article-title":"The combined dexamethasone\/CRH test: a refined laboratory test for psychiatric disorders","volume":"28","author":"Heuser","year":"1994","journal-title":"J Psychiatr Res"},{"issue":"7","key":"10.1016\/j.yebeh.2013.10.020_bb0390","doi-asserted-by":"crossref","first-page":"889","DOI":"10.1016\/j.psyneuen.2006.03.001","article-title":"The dex\/CRH test\u2014is it better than the DST?","volume":"31","author":"Watson","year":"2006","journal-title":"Psychoneuroendocrinology"},{"issue":"11","key":"10.1016\/j.yebeh.2013.10.020_bb0395","doi-asserted-by":"crossref","first-page":"922","DOI":"10.1016\/S0006-3223(01)01314-2","article-title":"A novel prednisolone suppression test for the hypothalamic\u2013pituitary\u2013adrenal axis","volume":"51","author":"Pariante","year":"2002","journal-title":"Biol Psychiatry"},{"key":"10.1016\/j.yebeh.2013.10.020_bb0400","series-title":"Williams textbook of endocrinology","first-page":"517","article-title":"The adrenal cortex","author":"Orth","year":"1998"},{"issue":"1\u20132","key":"10.1016\/j.yebeh.2013.10.020_bb0405","doi-asserted-by":"crossref","first-page":"200","DOI":"10.1007\/s00213-004-1925-4","article-title":"Four days of citalopram increase suppression of cortisol secretion by prednisolone in healthy volunteers","volume":"177","author":"Pariante","year":"2004","journal-title":"Psychopharmacology (Berl)"},{"issue":"6","key":"10.1016\/j.yebeh.2013.10.020_bb0410","doi-asserted-by":"crossref","first-page":"1963","DOI":"10.1210\/endo-109-6-1963","article-title":"Mineralocorticoid receptor-like aldosterone-binding protein in cell culture","volume":"109","author":"Lan","year":"1981","journal-title":"Endocrinology"},{"issue":"6","key":"10.1016\/j.yebeh.2013.10.020_bb0415","doi-asserted-by":"crossref","first-page":"998","DOI":"10.1001\/archinte.1958.00260230144018","article-title":"Aldosterone antagonists","volume":"102","author":"Liddle","year":"1958","journal-title":"AMA Arch Intern Med"},{"key":"10.1016\/j.yebeh.2013.10.020_bb0420","doi-asserted-by":"crossref","first-page":"931","DOI":"10.1016\/S0140-6736(59)91584-3","article-title":"Clinical and metabolic effects of aldosterone antagonism","volume":"2","author":"Slater","year":"1959","journal-title":"Lancet"},{"issue":"2","key":"10.1016\/j.yebeh.2013.10.020_bb0425","doi-asserted-by":"crossref","first-page":"290","DOI":"10.1210\/jcem-41-2-290","article-title":"A radioreceptor assay for evaluation of the plasma glucocorticoid activity of natural and synthetic steroids in man","volume":"41","author":"Ballard","year":"1975","journal-title":"J Clin Endocrinol Metab"},{"issue":"2","key":"10.1016\/j.yebeh.2013.10.020_bb0430","doi-asserted-by":"crossref","first-page":"332","DOI":"10.1210\/jcem-54-2-332","article-title":"Binding of steroids to mineralocorticoid receptors: implications for in vivo occupancy by glucocorticoids","volume":"54","author":"Lan","year":"1982","journal-title":"J Clin Endocrinol Metab"},{"issue":"3","key":"10.1016\/j.yebeh.2013.10.020_bb0435","doi-asserted-by":"crossref","first-page":"397","DOI":"10.1530\/eje.0.1510397","article-title":"Transactivation via the human glucocorticoid and mineralocorticoid receptor by therapeutically used steroids in CV-1 cells: a comparison of their glucocorticoid and mineralocorticoid properties","volume":"151","author":"Grossmann","year":"2004","journal-title":"Eur J Endocrinol"},{"issue":"4","key":"10.1016\/j.yebeh.2013.10.020_bb0440","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1016\/0306-4530(94)90013-2","article-title":"Salivary cortisol in psychoneuroendocrine research: recent developments and applications","volume":"19","author":"Kirschbaum","year":"1994","journal-title":"Psychoneuroendocrinology"},{"issue":"3","key":"10.1016\/j.yebeh.2013.10.020_bb0445","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1046\/j.1365-2265.1998.00549.x","article-title":"Reproducibility of the low dose dexamethasone suppression test: comparison between direct plasma and salivary cortisol assays","volume":"49","author":"Reynolds","year":"1998","journal-title":"Clin Endocrinol (Oxf)"},{"key":"10.1016\/j.yebeh.2013.10.020_bb0450","first-page":"P71","article-title":"New direct salivary cortisol and cortisone assays using the \u201cDelfia\u201d system","volume":"155","author":"Wood","year":"1997","journal-title":"J Endocrinol"},{"issue":"4","key":"10.1016\/j.yebeh.2013.10.020_bb0455","doi-asserted-by":"crossref","first-page":"342","DOI":"10.1192\/bjp.bp.108.050278","article-title":"Prednisolone suppression test in depression: prospective study of the role of HPA axis dysfunction in treatment resistance","volume":"194","author":"Juruena","year":"2009","journal-title":"Br J Psychiatry"},{"issue":"1\u20132","key":"10.1016\/j.yebeh.2013.10.020_bb0460","doi-asserted-by":"crossref","first-page":"279","DOI":"10.1016\/j.cca.2005.07.011","article-title":"Assessment of subtle changes in glucocorticoid negative feedback using prednisolone: comparison of salivary free cortisol and urinary cortisol metabolites as endpoints","volume":"364","author":"Jerjes","year":"2006","journal-title":"Clin Chim Acta"},{"issue":"4","key":"10.1016\/j.yebeh.2013.10.020_bb0465","doi-asserted-by":"crossref","first-page":"373","DOI":"10.1067\/mcp.2000.105762","article-title":"Effect of an oral contraceptive on the plasma levels of budesonide and prednisolone and the influence on plasma cortisol","volume":"67","author":"Seidegard","year":"2000","journal-title":"Clin Pharmacol Ther"},{"issue":"2","key":"10.1016\/j.yebeh.2013.10.020_bb0470","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1007\/s00213-006-0555-4","article-title":"Different responses to dexamethasone and prednisolone in the same depressed patients","volume":"189","author":"Juruena","year":"2006","journal-title":"Psychopharmacology (Berl)"},{"issue":"12","key":"10.1016\/j.yebeh.2013.10.020_bb0475","doi-asserted-by":"crossref","DOI":"10.1097\/NMD.0000000000000049","article-title":"The role of early life stress in adult psychiatric disorders. A systematic review according to childhood trauma subtypes","volume":"201","author":"Carr","year":"2013","journal-title":"J Nerv Ment Dis"},{"issue":"2","key":"10.1016\/j.yebeh.2013.10.020_bb0480","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1016\/S0145-2134(02)00541-0","article-title":"Development and validation of a brief screening version of the Childhood Trauma Questionnaire","volume":"27","author":"Bernstein","year":"2003","journal-title":"Child Abuse Negl"},{"issue":"Suppl. 2","key":"10.1016\/j.yebeh.2013.10.020_bb0485","first-page":"S41:8","article-title":"Childhood maltreatment and adult psychopathology: pathways to hypothalamic\u2013pituitary\u2013adrenal axis dysfunction","volume":"31","author":"Mello","year":"2009","journal-title":"Rev Bras Psiquiatr"},{"issue":"2","key":"10.1016\/j.yebeh.2013.10.020_bb0490","doi-asserted-by":"crossref","first-page":"229","DOI":"10.3922\/j.psns.2011.2.008","article-title":"Early life stress, HPA axis, and depression","volume":"4","author":"Tofoli","year":"2011","journal-title":"Psychol Neurosci"},{"issue":"24","key":"10.1016\/j.yebeh.2013.10.020_bb0495","doi-asserted-by":"crossref","first-page":"14293","DOI":"10.1073\/pnas.2336126100","article-title":"Differential responses to psychotherapy versus pharmacotherapy in patients with chronic forms of major depression and childhood trauma","volume":"100","author":"Nemeroff","year":"2003","journal-title":"Proc Natl Acad Sci (PNAS)"},{"key":"10.1016\/j.yebeh.2013.10.020_bb0500","doi-asserted-by":"crossref","first-page":"693","DOI":"10.1016\/j.psyneuen.2008.03.008","article-title":"The link between childhood trauma and depression: insights from HPA axis studies in humans","volume":"33","author":"Heim","year":"2008","journal-title":"Psychoneuroendocrinology"},{"issue":"1","key":"10.1016\/j.yebeh.2013.10.020_bb0505","doi-asserted-by":"crossref","first-page":"4","DOI":"10.1111\/j.1601-5215.2011.00610.x","article-title":"Assessment of the hypothalamic\u2013pituitary\u2013adrenal axis activity: glucocorticoid receptor and mineralocorticoid receptor function in depression with early life stress \u2014 a systematic review","volume":"24","author":"Von Werne Baes","year":"2012","journal-title":"Acta Neuropsychiatr"},{"key":"10.1016\/j.yebeh.2013.10.020_bb0510","doi-asserted-by":"crossref","first-page":"644","DOI":"10.1111\/j.1530-0277.2000.tb02035.x","article-title":"Rearing experiences and stress-induced plasma cortisol as early risk factors for excessive alcohol consumption in nonhuman primates","volume":"24","author":"Fahlke","year":"2000","journal-title":"Alcohol Clin Exp Res"},{"key":"10.1016\/j.yebeh.2013.10.020_bb0515","doi-asserted-by":"crossref","first-page":"433","DOI":"10.1002\/dev.420260802","article-title":"Social rearing effects on HPA axis activity over early development and in response to stress in rhesus monkeys","volume":"26","author":"Clarke","year":"1993","journal-title":"Dev Psychobiol"},{"key":"10.1016\/j.yebeh.2013.10.020_bb0520","doi-asserted-by":"crossref","first-page":"283","DOI":"10.2190\/N00C-HVD6-W8J8-7KXY","article-title":"Aims, organization, and initial studies of the Cross-National Project","volume":"7","author":"Gurland","year":"1976","journal-title":"Int J Aging Hum Dev"},{"key":"10.1016\/j.yebeh.2013.10.020_bb0525","series-title":"Diagnostic and Statistical Manual of Mental Disorders","author":"American Psychiatric Association","year":"1994"},{"issue":"Suppl. 1","key":"10.1016\/j.yebeh.2013.10.020_bb0530","first-page":"s13-8","article-title":"Depression and stress: is there an endophenotype?","volume":"29","author":"Mello","year":"2007","journal-title":"Rev Bras Psiquiatr"},{"issue":"8","key":"10.1016\/j.yebeh.2013.10.020_bb0535","doi-asserted-by":"crossref","first-page":"985","DOI":"10.1177\/0269881108092121","article-title":"Improved residual symptoms in bipolar affective disorder with adjunctive spironolactone (mineralocorticoid receptor antagonist): case series","volume":"23","author":"Juruena","year":"2009","journal-title":"J Psychopharmacol (Oxford)"},{"key":"10.1016\/j.yebeh.2013.10.020_bb0540","doi-asserted-by":"crossref","first-page":"3095","DOI":"10.1001\/jama.289.23.3095","article-title":"The epidemiology of major depressive disorder: results from the National Comorbidity Survey Replication (NCS-R)","volume":"289","author":"Kessler","year":"2003","journal-title":"JAMA"},{"issue":"67 Suppl. 6","key":"10.1016\/j.yebeh.2013.10.020_bb0545","first-page":"16","article-title":"Treatment-resistant depression","author":"Souery","year":"2006","journal-title":"J Clin Psychiatry"},{"key":"10.1016\/j.yebeh.2013.10.020_bb0550","doi-asserted-by":"crossref","first-page":"1486","DOI":"10.1016\/j.psyneuen.2010.04.016","article-title":"The prednisolone suppression test in depression: dose\u2013response and changes with antidepressant treatment","volume":"35","author":"Juruena","year":"2010","journal-title":"Psychoneuroendocrinology"},{"key":"10.1016\/j.yebeh.2013.10.020_bb0555","doi-asserted-by":"crossref","first-page":"23S","DOI":"10.1097\/00004714-199202001-00005","article-title":"Mechanisms of action of anticonvulsants in affective disorders: comparisons with lithium","volume":"12","author":"Post","year":"1992","journal-title":"J Clin Psychopharmacol"},{"key":"10.1016\/j.yebeh.2013.10.020_bb0560","doi-asserted-by":"crossref","first-page":"1020","DOI":"10.1038\/2141020a0","article-title":"Development of epileptic seizures through brain stimulation at low intensity","author":"Goddard","year":"1967","journal-title":"Nature"},{"key":"10.1016\/j.yebeh.2013.10.020_bb0565","doi-asserted-by":"crossref","first-page":"601","DOI":"10.1136\/jnnp.61.6.601","article-title":"Interictal mood and personality disorders in temporal lobe epilepsy and juvenile myoclonic epilepsy","volume":"61","author":"Perini","year":"1996","journal-title":"J Neurol Neurosurg Psychiatry"},{"key":"10.1016\/j.yebeh.2013.10.020_bb0570","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1016\/S0920-1211(99)00117-5","article-title":"Depression in patients with temporal lobe epilepsy is related to mesial temporal sclerosis","volume":"39","author":"Quiske","year":"2000","journal-title":"Epilepsy Res"},{"key":"10.1016\/j.yebeh.2013.10.020_bb0575","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1016\/0896-6974(94)00008-N","article-title":"Relationship of site of seizure focus to psychiatric morbidity","volume":"8","author":"Manchanda","year":"1995","journal-title":"J Epilepsy"},{"key":"10.1016\/j.yebeh.2013.10.020_bb0580","doi-asserted-by":"crossref","first-page":"441","DOI":"10.1006\/ebeh.2001.0242","article-title":"Prevalence of psychopathology in Dutch epilepsy patients: a comparative study","volume":"2","author":"Swinkels","year":"2001","journal-title":"Epilepsy Behav"},{"key":"10.1016\/j.yebeh.2013.10.020_bb0585","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1016\/S0091-3057(02)00791-8","article-title":"Multiple feedback mechanisms activating corticotropin-releasing hormone system in the brain during stress","volume":"73","author":"Makino","year":"2002","journal-title":"Pharmacol Biochem Behav"},{"key":"10.1016\/j.yebeh.2013.10.020_bb0590","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/S0165-1781(02)00243-3","article-title":"Dexamethasone-induced effects on lymphocyte distribution and expression of adhesion molecules in treatment-resistant depression","volume":"113","author":"Bauer","year":"2002","journal-title":"Psychiatry Res"},{"key":"10.1016\/j.yebeh.2013.10.020_bb0595","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1016\/S0306-4530(02)00009-4","article-title":"Altered glucocorticoid immunoregulation in treatment resistant depression","volume":"28","author":"Bauer","year":"2003","journal-title":"Psychoneuroendocrinology"},{"key":"10.1016\/j.yebeh.2013.10.020_bb0600","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1159\/000125210","article-title":"On the role of brain mineralocorticoid (Type I) and glucocorticoid (Type II) receptors in neuroendocrine regulation","volume":"50","author":"Ratka","year":"1989","journal-title":"Neuroendocrinology"},{"key":"10.1016\/j.yebeh.2013.10.020_bb0605","doi-asserted-by":"crossref","first-page":"655","DOI":"10.1016\/0306-4530(95)00003-7","article-title":"Corticosterone, brain mineralocorticoid receptors (MRs) and the activity of the hypothalamic\u2013pituitary\u2013adrenal (HPA) axis: the Lewis rat as an example of increased central MR capacity and a hyporesponsive HPA axis","volume":"20","author":"Oitzl","year":"1995","journal-title":"Psychoneuroendocrinology"},{"key":"10.1016\/j.yebeh.2013.10.020_bb0610","doi-asserted-by":"crossref","first-page":"2897","DOI":"10.1523\/JNEUROSCI.10-09-02897.1990","article-title":"Hippocampal damage associated with prolonged glucocorticoid exposure in primates","volume":"10","author":"Sapolsky","year":"1990","journal-title":"J Neurosci"},{"key":"10.1016\/j.yebeh.2013.10.020_bb0615","first-page":"3339","article-title":"The role of mineralocorticoid receptors in hypothalamic\u2013pituitary\u2013adrenal axis regulation in humans","volume":"83","author":"Young","year":"1998","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1016\/j.yebeh.2013.10.020_bb0620","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1001\/archpsyc.60.1.24","article-title":"Mineralocorticoid receptor function in major depression","volume":"60","author":"Young","year":"2003","journal-title":"Arch Gen Psychiatry"},{"key":"10.1016\/j.yebeh.2013.10.020_bb0625","doi-asserted-by":"crossref","first-page":"790","DOI":"10.1038\/sj.mp.4001679","article-title":"Direct targeting of hippocampal neurons for apoptosis by glucocorticoids is reversible by mineralocorticoid receptor activation","volume":"10","author":"Crochemore","year":"2005","journal-title":"Mol Psychiatry"},{"issue":"180","key":"10.1016\/j.yebeh.2013.10.020_bb0630","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1192\/bjp.180.2.99","article-title":"Cortisol, serotonin and depression: all stressed out?","author":"Cowen","year":"2002","journal-title":"Br J Psychiatry"},{"key":"10.1016\/j.yebeh.2013.10.020_bb0635","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1017\/S1461145701002218","article-title":"Corticosterone selectively attenuates 8-OH-DPAT-mediated hypothermia in mice","volume":"4","author":"McAllister-Williams","year":"2001","journal-title":"Int J Neuropsychopharmacol"},{"issue":"173","key":"10.1016\/j.yebeh.2013.10.020_bb0640","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/s00213-004-1774-1","article-title":"Corticosteroid\u2013serotonin interactions in depression: a review of the human evidence","author":"Porter","year":"2004","journal-title":"Psychopharmacology (Berl)"},{"issue":"143","key":"10.1016\/j.yebeh.2013.10.020_bb0645","doi-asserted-by":"crossref","first-page":"64","DOI":"10.1007\/s002130050920","article-title":"Effects of dexamethasone on neuroendocrine and psychological responses to l-tryptophan infusion","author":"Porter","year":"1999","journal-title":"Psychopharmacology (Berl)"},{"issue":"139","key":"10.1016\/j.yebeh.2013.10.020_bb0650","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1007\/s002130050711","article-title":"5-Hydroxytryptamine receptor function in humans is reduced by acute administration of hydrocortisone","author":"Porter","year":"1998","journal-title":"Psychopharmacology (Berl)"},{"key":"10.1016\/j.yebeh.2013.10.020_bb0655","doi-asserted-by":"crossref","first-page":"367","DOI":"10.1016\/j.biopsych.2003.10.007","article-title":"Long-term adaptations in glucocorticoid receptor and mineralocorticoid receptor mRNA and negative feedback on the hypothalamo-pituitary-adrenal axis following neonatal maternal separation","volume":"55","author":"Ladd","year":"2004","journal-title":"Biol Psychiatry"},{"key":"10.1016\/j.yebeh.2013.10.020_bb0660","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1017\/S1461145703004000","article-title":"Decreased expression of mineralocorticoid receptor mRNA in the prefrontal cortex in schizophrenia and bipolar disorder","volume":"7","author":"Xing","year":"2004","journal-title":"Int J Neuropsychopharmacol"},{"issue":"7","key":"10.1016\/j.yebeh.2013.10.020_bb0665","doi-asserted-by":"crossref","first-page":"985","DOI":"10.1038\/sj.mp.4001139","article-title":"Regional specificity of brain glucocorticoid receptor mRNA alterations in subjects with schizophrenia and mood disorders","author":"Webster","year":"2002","journal-title":"Mol Psychiatry"},{"key":"10.1016\/j.yebeh.2013.10.020_bb0670","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1016\/j.jad.2005.01.009","article-title":"Defining the boundaries of atypical depression: evidence from the HPA axis supports course of illness distinctions","volume":"86","author":"Stewart","year":"2005","journal-title":"J Affect Disord"},{"key":"10.1016\/j.yebeh.2013.10.020_bb0675","doi-asserted-by":"crossref","DOI":"10.1177\/0269881113499205","article-title":"The role of mineralocorticoid receptor function in treatment-resistant depression","author":"Juruena","year":"2013","journal-title":"J Psychopharmacol"},{"key":"10.1016\/j.yebeh.2013.10.020_bb0685","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.tins.2007.10.005","article-title":"The coming out of the brain mineralocorticoid receptor","volume":"31","author":"Joels","year":"2008","journal-title":"Trends Neurosci"},{"key":"10.1016\/j.yebeh.2013.10.020_bb0690","doi-asserted-by":"crossref","unstructured":"Otte C, Hinkelmann K, Moritz S, Yassouridis A, Jahn H, Wiedemann K, et al. Modulation of the mineralocorticoid receptor as add-on treatment in depression: a randomized, double-blind, placebo-controlled proof-of-concept study. J Psychiatr Res 44 (6): 339\u2014346.","DOI":"10.1016\/j.jpsychires.2009.10.006"},{"key":"10.1016\/j.yebeh.2013.10.020_bb0695","first-page":"S48","article-title":"Melancholia in Latin American studies: a distinct mood disorder for the ICD-11","volume":"33","author":"Juruena","year":"2011","journal-title":"Rev Bras Psiquiatr"},{"key":"10.1016\/j.yebeh.2013.10.020_bb9000","doi-asserted-by":"crossref","first-page":"1208","DOI":"10.1016\/j.psyneuen.2009.03.009","article-title":"Dex\/CRH test cortisol response in outpatients with major depression and matched healthy controls","volume":"34","author":"Carpenter","year":"2009","journal-title":"Psychoneuroendocrinology"},{"key":"10.1016\/j.yebeh.2013.10.020_bb9900","doi-asserted-by":"crossref","first-page":"889","DOI":"10.1016\/j.pnpbp.2009.04.011","article-title":"Effects of childhood trauma on HPA-axis reactivity in women free of lifetime psychopathology","volume":"33","author":"Klaassens","year":"2009","journal-title":"Prog Neuropsychopharmacology Biol Psychiatry"},{"key":"10.1016\/j.yebeh.2013.10.020_bb9800","doi-asserted-by":"crossref","first-page":"1147","DOI":"10.1016\/j.biopsych.2008.01.011","article-title":"Childhood parental loss and adult hypothalamic-pituitary-adrenal function","volume":"63","author":"Tyrka","year":"2008","journal-title":"Biol Psychiatry"},{"key":"10.1016\/j.yebeh.2013.10.020_bb9700","doi-asserted-by":"crossref","first-page":"617","DOI":"10.1001\/archgenpsychiatry.2009.50","article-title":"Major depressive disorder and hypothalamic-pituitary-adrenal axis activity: results from a large cohort study","volume":"66","author":"Vreeburg","year":"2009","journal-title":"Arch Gen Psychiatry"},{"key":"10.1016\/j.yebeh.2013.10.020_bb9600","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1016\/S0006-3223(03)00692-9","article-title":"Pituitary-adrenal responses to standard and low-dose dexamethasone suppression tests in adult survivors of child abuse","volume":"55","author":"Newport","year":"2004","journal-title":"Biol Psychiatry"}],"container-title":["Epilepsy & Behavior"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1525505013005532?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1525505013005532?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2022,3,17]],"date-time":"2022-03-17T00:34:03Z","timestamp":1647477243000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1525505013005532"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,9]]},"references-count":143,"alternative-id":["S1525505013005532"],"URL":"https:\/\/doi.org\/10.1016\/j.yebeh.2013.10.020","relation":{},"ISSN":["1525-5050"],"issn-type":[{"value":"1525-5050","type":"print"}],"subject":[],"published":{"date-parts":[[2014,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Early-life stress and HPA axis trigger recurrent adulthood depression","name":"articletitle","label":"Article Title"},{"value":"Epilepsy & Behavior","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.yebeh.2013.10.020","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2013 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}