{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,29]],"date-time":"2026-08-29T08:50:02Z","timestamp":1787993402537,"version":"build-2784847793"},"reference-count":30,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2018,4,1]],"date-time":"2018-04-01T00:00:00Z","timestamp":1522540800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":["epilepsybehavior.com","clinicalkey.jp","clinicalkey.com","clinicalkey.es","clinicalkey.fr","clinicalkey.com.au","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Epilepsy &amp; Behavior"],"published-print":{"date-parts":[[2018,4]]},"DOI":"10.1016\/j.yebeh.2018.01.036","type":"journal-article","created":{"date-parts":[[2018,2,17]],"date-time":"2018-02-17T18:24:16Z","timestamp":1518891856000},"page":"33-40","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":30,"special_numbering":"C","title":["Effects of vagus nerve stimulation on heart rate variability in children with epilepsy"],"prefix":"10.1016","volume":"81","author":[{"given":"Tugba","family":"Hirfanoglu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ayse","family":"Serdaroglu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ilker","family":"Cetin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gokhan","family":"Kurt","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Irem Y.","family":"Capraz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Filiz","family":"Ekici","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ebru","family":"Arhan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Erhan","family":"Bilir","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.yebeh.2018.01.036_bb0005","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1111\/head.12647","article-title":"Vagus nerve and vagus nerve stimulation, a comprehensive review: part I","volume":"56","author":"Yuan","year":"2016","journal-title":"Headache"},{"key":"10.1016\/j.yebeh.2018.01.036_bb0010","doi-asserted-by":"crossref","first-page":"259","DOI":"10.1111\/head.12650","article-title":"Vagus nerve and vagus nerve stimulation, a comprehensive review: part II","volume":"56","author":"Yuan","year":"2016","journal-title":"Headache"},{"key":"10.1016\/j.yebeh.2018.01.036_bb0015","doi-asserted-by":"crossref","first-page":"455","DOI":"10.1016\/j.seizure.2010.07.008","article-title":"Cardiac changes in epilepsy","volume":"19","author":"Jansen","year":"2010","journal-title":"Seizure"},{"key":"10.1016\/j.yebeh.2018.01.036_bb0020","doi-asserted-by":"crossref","first-page":"556","DOI":"10.1111\/j.1528-1167.2006.00467.x","article-title":"Cardiac autonomic control in patients with refractory epilepsy before and during vagus nerve stimulation treatment: a one-year follow-up study","volume":"47","author":"Ronkainen","year":"2006","journal-title":"Epilepsia"},{"key":"10.1016\/j.yebeh.2018.01.036_bb0025","doi-asserted-by":"crossref","first-page":"1143","DOI":"10.1111\/j.1469-8749.2011.04103.x","article-title":"Autonomic effects of refractory epilepsy on heart rate variability in children: influence of intermittent vagus nerve stimulation","volume":"53","author":"Jansen","year":"2011","journal-title":"Dev Med Child Neurol"},{"key":"10.1016\/j.yebeh.2018.01.036_bb0030","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1016\/j.seizure.2014.01.025","article-title":"Can heart rate variability in children with epilepsy be used to predict seizures?","volume":"23","author":"Kolsal","year":"2014","journal-title":"Seizure"},{"key":"10.1016\/j.yebeh.2018.01.036_bb0035","doi-asserted-by":"crossref","first-page":"277","DOI":"10.1016\/j.eplepsyres.2009.08.008","article-title":"Do alterations in inter-ictal heart rate variability predict sudden unexpected death in epilepsy?","volume":"87","author":"Surges","year":"2009","journal-title":"Epilepsy Res"},{"key":"10.1016\/j.yebeh.2018.01.036_bb0040","doi-asserted-by":"crossref","first-page":"255","DOI":"10.4103\/2152-7806.103015","article-title":"Vagus nerve stimulation for epilepsy: a review of central mechanisms","volume":"3","author":"Krahl","year":"2012","journal-title":"Surg Neurol Int"},{"key":"10.1016\/j.yebeh.2018.01.036_bb0045","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1113\/expphysiol.2014.082842","article-title":"Vagus nerve stimulation reverses ventricular electrophysiological changes induced by hypersympathetic nerve activity","volume":"100","author":"Huang","year":"2015","journal-title":"Exp Physiol"},{"key":"10.1016\/j.yebeh.2018.01.036_bb0050","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1111\/j.1600-0404.2007.00944.x","article-title":"Effects of vagus nerve stimulation on cardiovascular regulation in patients with epilepsy","volume":"117","author":"Stemper","year":"2008","journal-title":"Acta Neurol Scand"},{"key":"10.1016\/j.yebeh.2018.01.036_bb0055","doi-asserted-by":"crossref","first-page":"479","DOI":"10.1111\/head.12649","article-title":"Vagus nerve and vagus nerve stimulation, a comprehensive review: part III","volume":"56","author":"Yuan","year":"2016","journal-title":"Headache"},{"key":"10.1016\/j.yebeh.2018.01.036_bb0060","doi-asserted-by":"crossref","first-page":"923","DOI":"10.1111\/j.1528-1167.2006.01019.x","article-title":"Vagus nerve stimulation therapy induces changes in heart rate of children during sleep","volume":"48","author":"Zaaimi","year":"2007","journal-title":"Epilepsia"},{"key":"10.1016\/j.yebeh.2018.01.036_bb0065","doi-asserted-by":"crossref","first-page":"1579","DOI":"10.1152\/ajpheart.00558.2015","article-title":"Vagal nerve stimulation activates vagal afferent fibers that reduce cardiac efferent parasympathetic effects","volume":"309","author":"Yamakawa","year":"2015","journal-title":"Am J Physiol Heart Circ Physiol"},{"key":"10.1016\/j.yebeh.2018.01.036_bb0070","doi-asserted-by":"crossref","first-page":"338","DOI":"10.1007\/s11517-006-0041-5","article-title":"Cardiorespiratory effects induced by vagus nerve stimulation in epileptic children","volume":"44","author":"Pruvost","year":"2006","journal-title":"Med Biol Eng Comput"},{"key":"10.1016\/j.yebeh.2018.01.036_bb0075","doi-asserted-by":"crossref","first-page":"602","DOI":"10.1007\/s003810100505","article-title":"Power spectrum analysis of heart rate variability in children with epilepsy","volume":"17","author":"Yang","year":"2001","journal-title":"Childs Nerv Syst"},{"key":"10.1016\/j.yebeh.2018.01.036_bb0080","doi-asserted-by":"crossref","first-page":"2473","DOI":"10.1111\/j.1528-1167.2009.02190.x","article-title":"Vagus nerve stimulation induces changes in respiratory sinus arrhythmia of epileptic children during sleep","volume":"50","author":"Zaaimi","year":"2009","journal-title":"Epilepsia"},{"key":"10.1016\/j.yebeh.2018.01.036_bb0085","doi-asserted-by":"crossref","first-page":"52","DOI":"10.1016\/S1566-0702(03)00081-X","article-title":"Analysis of RR variability in drug-resistant epilepsy patients chronically treated with vagus nerve stimulation","volume":"107","author":"Galli","year":"2003","journal-title":"Auton Neurosci"},{"key":"10.1016\/j.yebeh.2018.01.036_bb0090","doi-asserted-by":"crossref","first-page":"1015","DOI":"10.1111\/epi.13738","article-title":"Heart-rate variability indices as predictors of the response to vagus nerve stimulation in patients with drug-resistant epilepsy","volume":"58","author":"Liu","year":"2017","journal-title":"Epilepsia"},{"key":"10.1016\/j.yebeh.2018.01.036_bb0095","first-page":"551996","article-title":"Vagus nerve stimulation reduces cardiac electrical instability assessed by quantitative T-wave alternans analysis in patients with drug-resistant focal epilepsy","author":"Schomer","year":"2014","journal-title":"Epilepsia"},{"key":"10.1016\/j.yebeh.2018.01.036_bb0100","doi-asserted-by":"crossref","first-page":"316","DOI":"10.1111\/ane.12009","article-title":"Long-term vagus nerve stimulation in children with focal epilepsy","volume":"127","author":"Ryz\u00ed","year":"2013","journal-title":"Acta Neurol Scand"},{"key":"10.1016\/j.yebeh.2018.01.036_bb0105","doi-asserted-by":"crossref","first-page":"334","DOI":"10.1016\/j.ejpn.2009.09.010","article-title":"The efficacy of vagal nerve stimulation in children with pharmacoresistant epilepsy: practical experience at a Turkish tertiary referral center","volume":"14","author":"Arhan","year":"2010","journal-title":"Eur J Paediatr Neurol"},{"key":"10.1016\/j.yebeh.2018.01.036_bb0110","doi-asserted-by":"crossref","first-page":"272","DOI":"10.1111\/j.1528-1167.2011.03361.x","article-title":"A systematic review and meta-analysis of heart rate variability in epilepsy and antiepileptic drugs","volume":"53","author":"Lotufo","year":"2012","journal-title":"Epilepsia"},{"key":"10.1016\/j.yebeh.2018.01.036_bb0115","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1016\/j.eplepsyres.2007.12.020","article-title":"Effects of antiepileptic drug therapy on heart rate variability in children with epilepsy","volume":"79","author":"Hallioglu","year":"2008","journal-title":"Epilepsy Res"},{"key":"10.1016\/j.yebeh.2018.01.036_bb0120","doi-asserted-by":"crossref","first-page":"419","DOI":"10.1016\/j.pediatrneurol.2014.11.018","article-title":"Cardiac autonomic balance in children with epilepsy: value of antiepileptic drugs","volume":"52","author":"El-Rashidy","year":"2015","journal-title":"Pediatr Neurol"},{"key":"10.1016\/j.yebeh.2018.01.036_bb0125","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1016\/j.eplepsyres.2005.02.001","article-title":"Time and frequency domain analyses of heart rate variability in patients with epilepsy","volume":"63","author":"Evreng\u00fcl","year":"2005","journal-title":"Epilepsy Res"},{"key":"10.1016\/j.yebeh.2018.01.036_bb0130","doi-asserted-by":"crossref","first-page":"641","DOI":"10.1007\/s00381-015-3004-z","article-title":"Long term effect of vagus nerve stimulation in pediatric intractable epilepsy: an extended follow-up","volume":"32","author":"Serdaroglu","year":"2016","journal-title":"Childs Nerv Syst"},{"key":"10.1016\/j.yebeh.2018.01.036_bb0135","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1016\/j.eplepsyres.2009.03.021","article-title":"Cardiovascular autonomic functions in well-controlled and intractable partial epilepsies","volume":"85","author":"Mukherjee","year":"2009","journal-title":"Epilepsy Res"},{"key":"10.1016\/j.yebeh.2018.01.036_bb0140","doi-asserted-by":"crossref","first-page":"379","DOI":"10.1016\/B978-0-444-53491-0.00031-6","article-title":"Heart rate variability","volume":"117","author":"Cygankiewicz","year":"2013","journal-title":"Handb Clin Neurol"},{"key":"10.1016\/j.yebeh.2018.01.036_bb0145","doi-asserted-by":"crossref","first-page":"1043","DOI":"10.1161\/01.CIR.93.5.1043","volume":"93","year":"1996","journal-title":"Circulation"},{"key":"10.1016\/j.yebeh.2018.01.036_bb0150","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1016\/j.seizure.2016.11.018","article-title":"Cardiovascular autonomic and hemodynamic responses to vagus nerve stimulation in drug-resistant epilepsy","volume":"45","author":"Garamendi","year":"2017","journal-title":"Seizure"}],"container-title":["Epilepsy &amp; Behavior"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1525505017309861?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1525505017309861?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2018,8,23]],"date-time":"2018-08-23T20:55:58Z","timestamp":1535057758000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1525505017309861"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,4]]},"references-count":30,"alternative-id":["S1525505017309861"],"URL":"https:\/\/doi.org\/10.1016\/j.yebeh.2018.01.036","relation":{},"ISSN":["1525-5050"],"issn-type":[{"value":"1525-5050","type":"print"}],"subject":[],"published":{"date-parts":[[2018,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Effects of vagus nerve stimulation on heart rate variability in children with epilepsy","name":"articletitle","label":"Article Title"},{"value":"Epilepsy & Behavior","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.yebeh.2018.01.036","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2018 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}