{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,19]],"date-time":"2026-03-19T22:23:16Z","timestamp":1773958996103,"version":"3.50.1"},"reference-count":40,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2020,10,1]],"date-time":"2020-10-01T00:00:00Z","timestamp":1601510400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,10,1]],"date-time":"2020-10-01T00:00:00Z","timestamp":1601510400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2020,6,10]],"date-time":"2020-06-10T00:00:00Z","timestamp":1591747200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Qatar National Library"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","epilepsybehavior.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Epilepsy & Behavior"],"published-print":{"date-parts":[[2020,10]]},"DOI":"10.1016\/j.yebeh.2020.107241","type":"journal-article","created":{"date-parts":[[2020,6,23]],"date-time":"2020-06-23T05:49:16Z","timestamp":1592891356000},"page":"107241","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":10,"special_numbering":"C","title":["Unexpected brain imaging findings in patients with seizures"],"prefix":"10.1016","volume":"111","author":[{"given":"Boulenouar","family":"Mesraoua","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Matthias","family":"Koepp","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bernhard","family":"Schuknecht","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dirk","family":"Deleu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hassan J.","family":"Al Hail","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gayane","family":"Melikyan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lubna","family":"Elsheikh","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ali A.","family":"Asadi-Pooya","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"10","key":"10.1016\/j.yebeh.2020.107241_bb0005","doi-asserted-by":"crossref","first-page":"537","DOI":"10.1038\/nrneurol.2010.131","article-title":"Imaging in the surgical treatment of epilepsy","volume":"6","author":"Duncan","year":"2010","journal-title":"Nat Rev Neurol"},{"issue":"2","key":"10.1016\/j.yebeh.2020.107241_bb0010","doi-asserted-by":"crossref","first-page":"384","DOI":"10.1602\/neurorx.2.2.384","article-title":"Neuroimaging of epilepsy: therapeutic implications","volume":"2","author":"Kuzniecky","year":"2005","journal-title":"NeuroRx"},{"issue":"4","key":"10.1016\/j.yebeh.2020.107241_bb0015","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1055\/s-2008-1063979","article-title":"Neuroimaging in epilepsy: contribution of MRI, PET and SPECT","volume":"10","author":"Sperling","year":"1990","journal-title":"Semin Neurol"},{"issue":"Pt 11","key":"10.1016\/j.yebeh.2020.107241_bb0020","doi-asserted-by":"crossref","first-page":"2396","DOI":"10.1093\/brain\/awg239","article-title":"Magnetic brain source imaging of focal epileptic activity: a synopsis of 455 cases","volume":"126","author":"Stefan","year":"2003","journal-title":"Brain"},{"issue":"3","key":"10.1016\/j.yebeh.2020.107241_bb0025","doi-asserted-by":"crossref","first-page":"346","DOI":"10.1001\/archneur.55.3.346","article-title":"Failure of standard magnetic resonance imaging in patients with refractory temporal lobe epilepsy","volume":"55","author":"McBride","year":"1998","journal-title":"Arch Neurol"},{"issue":"6","key":"10.1016\/j.yebeh.2020.107241_bb0030","doi-asserted-by":"crossref","first-page":"643","DOI":"10.1136\/jnnp.73.6.643","article-title":"Standard magnetic resonance imaging is inadequate for patients with refractory focal epilepsy","volume":"73","author":"Von Oertzen","year":"2002","journal-title":"J Neurol Neurosurg Psychiatry"},{"key":"10.1016\/j.yebeh.2020.107241_bb0035","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1001\/jama.282.1.36","article-title":"Incidental findings on brain magnetic resonance imaging from 1000 asymptomatic volunteers","volume":"282","author":"Katzman","year":"1999","journal-title":"JAMA"},{"key":"10.1016\/j.yebeh.2020.107241_bb0040","doi-asserted-by":"crossref","first-page":"60","DOI":"10.1016\/j.yebeh.2015.03.015","article-title":"Epidemiology of psychogenic non-epileptic seizures","volume":"46","author":"Asadi-Pooya","year":"2015","journal-title":"Epilepsy Behav"},{"key":"10.1016\/j.yebeh.2020.107241_bb0045","doi-asserted-by":"crossref","first-page":"256","DOI":"10.1016\/j.yebeh.2015.09.020","article-title":"Neurobiological origin of psychogenic nonepileptic seizures: a review of imaging studies","volume":"52","author":"Asadi-Pooya","year":"2015","journal-title":"Epilepsy Behav"},{"key":"10.1016\/j.yebeh.2020.107241_bb0050","doi-asserted-by":"crossref","first-page":"555","DOI":"10.1007\/s10072-019-04108-7","article-title":"Structural brain abnormalities in patients with psychogenic nonepileptic seizures","volume":"41","author":"Asadi-Pooya","year":"2020","journal-title":"Neurol Sci"},{"key":"10.1016\/j.yebeh.2020.107241_bb0055","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1016\/j.yebeh.2018.06.015","article-title":"Utilization of brain imaging in evaluating patients with psychogenic nonepileptic spells","volume":"85","author":"Wei","year":"2018","journal-title":"Epilepsy Behav"},{"key":"10.1016\/j.yebeh.2020.107241_bb0060","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1016\/j.yebeh.2016.02.036","article-title":"Prevalence and distribution of MRI abnormalities in patients with psychogenic nonepileptic events","volume":"59","author":"Bolen","year":"2016","journal-title":"Epilepsy Behav"},{"key":"10.1016\/j.yebeh.2020.107241_bb0065","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1016\/S1525-5050(02)00004-5","article-title":"Evidence of brain abnormality in patients with psychogenic nonepileptic seizures","volume":"3","author":"Reuber","year":"2002","journal-title":"Epilepsy Behav"},{"key":"10.1016\/j.yebeh.2020.107241_bb0070","doi-asserted-by":"crossref","first-page":"210","DOI":"10.1016\/j.nicl.2017.07.025","article-title":"Neuroimaging studies in patients with psychogenic non-epileptic seizures: a systematic meta-review","volume":"16","author":"Mcsweeney","year":"2017","journal-title":"Neuroimage Clin"},{"key":"10.1016\/j.yebeh.2020.107241_bb0075","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1016\/j.jns.2012.10.014","article-title":"A clinical study of syndromes of idiopathic (genetic) generalized epilepsy","volume":"324","author":"Asadi-Pooya","year":"2013","journal-title":"J Neurol Sci"},{"issue":"Suppl. 2","key":"10.1016\/j.yebeh.2020.107241_bb0080","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1046\/j.1528-1157.44.s.2.2.x","article-title":"From molecules to networks: cortical\/subcortical interactions in the pathophysiology of idiopathic generalized epilepsy","volume":"44","author":"Blumenfeld","year":"2003","journal-title":"Epilepsia"},{"key":"10.1016\/j.yebeh.2020.107241_bb0085","doi-asserted-by":"crossref","first-page":"373","DOI":"10.1016\/j.neuroimage.2009.01.055","article-title":"Thalamo\u2013cortical network pathology in idiopathic generalized epilepsy: insights from MRI-based morphometric correlation analysis","volume":"46","author":"Bernhardt","year":"2009","journal-title":"NeuroImage"},{"key":"10.1016\/j.yebeh.2020.107241_bb0090","doi-asserted-by":"crossref","first-page":"2912","DOI":"10.1093\/brain\/awr223","article-title":"Altered functional\u2013structural coupling of large-scale brain networks in idiopathic generalized epilepsy","volume":"134","author":"Zhang","year":"2011","journal-title":"Brain"},{"issue":"42","key":"10.1016\/j.yebeh.2020.107241_bb0095","doi-asserted-by":"crossref","first-page":"15236","DOI":"10.1073\/pnas.0504935102","article-title":"Generalized epileptic discharges show thalamocortical activation and suspension of the default state of the brain","volume":"102","author":"Gotman","year":"2005","journal-title":"Proc Natl Acad Sci U S A"},{"issue":"3","key":"10.1016\/j.yebeh.2020.107241_bb0100","doi-asserted-by":"crossref","first-page":"515","DOI":"10.1111\/j.1528-1167.2010.02938.x","article-title":"Functional connectivity in patients with idiopathic generalized epilepsy","volume":"52","author":"Moeller","year":"2011","journal-title":"Epilepsia"},{"issue":"4","key":"10.1016\/j.yebeh.2020.107241_bb0105","doi-asserted-by":"crossref","first-page":"592","DOI":"10.1111\/epi.12580","article-title":"Altered thalamocortical functional connectivity in idiopathic generalized epilepsy","volume":"55","author":"Kim","year":"2014","journal-title":"Epilepsia"},{"issue":"3","key":"10.1016\/j.yebeh.2020.107241_bb0110","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1016\/S1525-5050(02)00029-X","article-title":"The role of subcortical structures in human epilepsy","volume":"3","author":"Norden","year":"2002","journal-title":"Epilepsy Behav"},{"issue":"12","key":"10.1016\/j.yebeh.2020.107241_bb0115","doi-asserted-by":"crossref","first-page":"3635","DOI":"10.1093\/brain\/aws296","article-title":"Abnormal thalamocortical structural and functional connectivity in juvenile myoclonic epilepsy","volume":"135","author":"O'Muircheartaigh","year":"2012","journal-title":"Brain"},{"issue":"12","key":"10.1016\/j.yebeh.2020.107241_bb0120","doi-asserted-by":"crossref","first-page":"2091","DOI":"10.1111\/epi.12003","article-title":"Frontal lobe function and structure in juvenile myoclonic epilepsy: a comprehensive review of neuropsychological and imaging data","volume":"53","author":"Wandschneider","year":"2012","journal-title":"Epilepsia"},{"issue":"6","key":"10.1016\/j.yebeh.2020.107241_bb0125","doi-asserted-by":"crossref","first-page":"1710","DOI":"10.1093\/brain\/awr098","article-title":"Motor system hyperconnectivity in juvenile myoclonic epilepsy: a cognitive functional magnetic resonance imaging study","volume":"134","author":"Vollmar","year":"2011","journal-title":"Brain"},{"issue":"20","key":"10.1016\/j.yebeh.2020.107241_bb0130","doi-asserted-by":"crossref","first-page":"1555","DOI":"10.1212\/WNL.0b013e3182563b44","article-title":"Altered microstructural connectivity in juvenile myoclonic epilepsy: the missing link","volume":"78","author":"Vollmar","year":"2012","journal-title":"Neurology"},{"issue":"3","key":"10.1016\/j.yebeh.2020.107241_bb0135","doi-asserted-by":"crossref","first-page":"471","DOI":"10.1111\/epi.12062","article-title":"The relationship between the localization of the generalized spike and wave discharge generators and the response to valproate","volume":"54","author":"Szaflarski","year":"2013","journal-title":"Epilepsia"},{"issue":"2","key":"10.1016\/j.yebeh.2020.107241_bb0140","doi-asserted-by":"crossref","first-page":"256","DOI":"10.1111\/epi.12486","article-title":"Differences in paracingulate connectivity associated with epileptiform discharges and uncontrolled seizures in genetic generalized epilepsy","volume":"55","author":"Kay","year":"2014","journal-title":"Epilepsia"},{"key":"10.1016\/j.yebeh.2020.107241_bb0145","doi-asserted-by":"crossref","first-page":"660","DOI":"10.1002\/ana.24240","article-title":"Neurodevelopment in new-onset juvenile myoclonic epilepsy over the first 2 years","volume":"76","author":"Lin","year":"2014","journal-title":"Ann Neurol"},{"key":"10.1016\/j.yebeh.2020.107241_bb0150","doi-asserted-by":"crossref","first-page":"2670","DOI":"10.1093\/brain\/awz215","article-title":"Abnormal hippocampal structure and function in juvenile myoclonic epilepsy and unaffected siblings","volume":"142","author":"Caciagli","year":"2019","journal-title":"Brain"},{"key":"10.1016\/j.yebeh.2020.107241_bb0155","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0015219","article-title":"Cerebellum abnormalities in idiopathic generalized epilepsy with generalized tonic-clonic seizures revealed by diffusion tensor imaging","volume":"5","author":"Li","year":"2010","journal-title":"PLoS ONE"},{"key":"10.1016\/j.yebeh.2020.107241_bb0160","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1016\/j.yebeh.2009.02.033","article-title":"Neuropathology of focal epilepsies: a critical review","volume":"15","author":"Bl\u00fcmke","year":"2009","journal-title":"Epilepsy Behav"},{"key":"10.1016\/j.yebeh.2020.107241_bb0165","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1038\/nrneurol.2010.199","article-title":"Advances in MR for \u2018cryptogenic\u2019 epilepsies","volume":"7","author":"Bernasconi","year":"2011","journal-title":"Nat Rev Neurol"},{"key":"10.1016\/j.yebeh.2020.107241_bb0170","doi-asserted-by":"crossref","first-page":"346","DOI":"10.1001\/archneur.55.3.346","article-title":"Failure of standard magnetic resonance imaging in patients with refractory temporal lobe epilepsy","volume":"553","author":"McBride","year":"1998","journal-title":"Arch Neurol"},{"key":"10.1016\/j.yebeh.2020.107241_bb0175","doi-asserted-by":"crossref","first-page":"542","DOI":"10.1148\/radiol.12112638","article-title":"Temporal lobe epilepsy quantitative MR volumetry in detection of hippocampal atrophy","volume":"264","author":"Farid","year":"2012","journal-title":"Radiology"},{"key":"10.1016\/j.yebeh.2020.107241_bb0180","doi-asserted-by":"crossref","first-page":"77","DOI":"10.3174\/ajnr.A3640","article-title":"3T MRI quantification of hippocampal volume and signal in mesial temporal lobe epilepsy improves detection of hippocampal sclerosis","volume":"35","author":"Coan","year":"2014","journal-title":"AJNR"},{"key":"10.1016\/j.yebeh.2020.107241_bb0185","doi-asserted-by":"crossref","first-page":"294","DOI":"10.1016\/j.neuroimage.2017.06.002","article-title":"Preferential susceptibility of limbic cortices to microstructural damage intemporal lobe epilepsy: a quantitative T1 mapping study","volume":"182","author":"Bernhardt","year":"2018","journal-title":"NeuroImage"},{"key":"10.1016\/j.yebeh.2020.107241_bb0190","doi-asserted-by":"crossref","first-page":"126","DOI":"10.1034\/j.1600-0404.2003.00183.x","article-title":"Temporal lobe epilepsy: analysis of patients with dual pathology","volume":"109","author":"Salanova","year":"2004","journal-title":"Acta Neurol Scand"},{"key":"10.1016\/j.yebeh.2020.107241_bb0195","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1111\/epi.13615","article-title":"Temporal lobe epilepsy and focal cortical dysplasia in children: a tip to find the abnormality","volume":"58","author":"Bartolini","year":"2017","journal-title":"Epilepsia"},{"key":"10.1016\/j.yebeh.2020.107241_bb0200","doi-asserted-by":"crossref","first-page":"82","DOI":"10.1093\/brain\/awh687","article-title":"Epileptogenicity of cortical dysplasia in temporal lobe dual pathology: an electrophysiological study with invasive recordings","volume":"129","author":"Fauser","year":"2006","journal-title":"Brain"}],"container-title":["Epilepsy & Behavior"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1525505020304200?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1525505020304200?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,26]],"date-time":"2025-10-26T18:37:26Z","timestamp":1761503846000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1525505020304200"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,10]]},"references-count":40,"alternative-id":["S1525505020304200"],"URL":"https:\/\/doi.org\/10.1016\/j.yebeh.2020.107241","relation":{},"ISSN":["1525-5050"],"issn-type":[{"value":"1525-5050","type":"print"}],"subject":[],"published":{"date-parts":[[2020,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Unexpected brain imaging findings in patients with seizures","name":"articletitle","label":"Article Title"},{"value":"Epilepsy & Behavior","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.yebeh.2020.107241","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2020 The Authors. Published by Elsevier Inc.","name":"copyright","label":"Copyright"}],"article-number":"107241"}}